BR0116123A - Carbazóis antitumorais - Google Patents
Carbazóis antitumoraisInfo
- Publication number
- BR0116123A BR0116123A BR0116123-7A BR0116123A BR0116123A BR 0116123 A BR0116123 A BR 0116123A BR 0116123 A BR0116123 A BR 0116123A BR 0116123 A BR0116123 A BR 0116123A
- Authority
- BR
- Brazil
- Prior art keywords
- carbazoles
- antitumor
- medicine
- relates
- carbazois
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
"CARBAZóIS ANTITUMORAIS". A invenção provê um composto da fórmula (I). Esta invenção refere-se a compostos heterocíclicos. Ela refere-se ainda a métodos para sua preparação, composições contendo-os e seu uso como um medicamento, particularmente como medicamento para o tratamento e profilaxia de câncer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0030417.0A GB0030417D0 (en) | 2000-12-13 | 2000-12-13 | An anticancer lead compound isolated from a New Zealand ascidian |
PCT/GB2001/005523 WO2002048107A1 (en) | 2000-12-13 | 2001-12-13 | Antitumoral carbazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0116123A true BR0116123A (pt) | 2003-10-14 |
Family
ID=9905016
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0116123-7A BR0116123A (pt) | 2000-12-13 | 2001-12-13 | Carbazóis antitumorais |
Country Status (11)
Country | Link |
---|---|
US (1) | US7135494B2 (pt) |
EP (1) | EP1349837A1 (pt) |
JP (1) | JP2004518650A (pt) |
AU (1) | AU2002217266A1 (pt) |
BR (1) | BR0116123A (pt) |
CA (1) | CA2431107A1 (pt) |
GB (1) | GB0030417D0 (pt) |
IL (1) | IL156372A0 (pt) |
MX (1) | MXPA03005374A (pt) |
NZ (1) | NZ526399A (pt) |
WO (1) | WO2002048107A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8530496B2 (en) | 2008-07-08 | 2013-09-10 | Trustees Of Dartmouth College | Compositions and methods for treating cancer |
US8765781B2 (en) * | 2008-07-08 | 2014-07-01 | Trustees Of Dartmouth College | Bis-carbazole DNA intercalating agents for antitumor therapy |
US8975274B2 (en) | 2011-09-20 | 2015-03-10 | Trustees Of Dartmouth College | Compositions and methods for treating cancer |
SG10201704588XA (en) | 2012-09-25 | 2017-07-28 | Chugai Pharmaceutical Co Ltd | Ret inhibitor |
CA2946518C (en) | 2014-04-25 | 2022-07-26 | Chugai Seiyaku Kabushiki Kaisha | Preparation containing tetracyclic compound at high dose |
TWI752901B (zh) | 2015-01-16 | 2022-01-21 | 日商中外製藥股份有限公司 | 合併用醫藥 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
CA3107270A1 (en) | 2018-09-04 | 2020-03-12 | Chugai Seiyaku Kabushiki Kaisha | Method for producing tetracyclic compound |
WO2023220558A1 (en) * | 2022-05-09 | 2023-11-16 | Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center | Combination of curaxins and immune checkpoint inhibitors for treating cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0331257A (ja) | 1989-06-28 | 1991-02-12 | Kissei Pharmaceut Co Ltd | インドール誘導体の製造方法 |
CA2108889A1 (en) | 1991-05-29 | 1992-11-30 | Robert Lee Dow | Tricyclic polyhydroxylic tyrosine kinase inhibitors |
JPH08157475A (ja) | 1994-11-29 | 1996-06-18 | Kissei Pharmaceut Co Ltd | 1−ヒドロキシインドール誘導体 |
-
2000
- 2000-12-13 GB GBGB0030417.0A patent/GB0030417D0/en not_active Ceased
-
2001
- 2001-12-13 BR BR0116123-7A patent/BR0116123A/pt not_active IP Right Cessation
- 2001-12-13 WO PCT/GB2001/005523 patent/WO2002048107A1/en active IP Right Grant
- 2001-12-13 JP JP2002549638A patent/JP2004518650A/ja active Pending
- 2001-12-13 US US10/450,594 patent/US7135494B2/en not_active Expired - Fee Related
- 2001-12-13 AU AU2002217266A patent/AU2002217266A1/en not_active Abandoned
- 2001-12-13 EP EP01270529A patent/EP1349837A1/en not_active Withdrawn
- 2001-12-13 IL IL15637201A patent/IL156372A0/xx unknown
- 2001-12-13 CA CA002431107A patent/CA2431107A1/en not_active Abandoned
- 2001-12-13 MX MXPA03005374A patent/MXPA03005374A/es unknown
- 2001-12-13 NZ NZ526399A patent/NZ526399A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2431107A1 (en) | 2002-06-20 |
IL156372A0 (en) | 2004-01-04 |
US7135494B2 (en) | 2006-11-14 |
JP2004518650A (ja) | 2004-06-24 |
WO2002048107A1 (en) | 2002-06-20 |
AU2002217266A1 (en) | 2002-06-24 |
MXPA03005374A (es) | 2004-03-26 |
US20040072890A1 (en) | 2004-04-15 |
GB0030417D0 (en) | 2001-01-24 |
EP1349837A1 (en) | 2003-10-08 |
NZ526399A (en) | 2005-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 7A. E 8A. ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2021 DE 29/09/2009. |