BR0013754A - Formulação veterinaria para administração de uma droga insolúvel em água a um animal alvo através de um sistema de distribuição de água - Google Patents

Formulação veterinaria para administração de uma droga insolúvel em água a um animal alvo através de um sistema de distribuição de água

Info

Publication number
BR0013754A
BR0013754A BR0013754-5A BR0013754A BR0013754A BR 0013754 A BR0013754 A BR 0013754A BR 0013754 A BR0013754 A BR 0013754A BR 0013754 A BR0013754 A BR 0013754A
Authority
BR
Brazil
Prior art keywords
water
distribution system
formulation
drug
target animal
Prior art date
Application number
BR0013754-5A
Other languages
English (en)
Inventor
Peter Frank Ekhart
Mario Van Wandelen
Jan Matthijs Jetten
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BR0013754A publication Critical patent/BR0013754A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Colloid Chemistry (AREA)
  • Fodder In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"FORMULAçãO VETERINáRIA PARA ADMINISTRAçãO DE UMA DROGA INSOLúVEL EM áGUA A UM ANIMAL ALVO ATRAVéS DE UM SISTEMA DE DISTRIBUIçãO DE áGUA". Esta invenção refere-se a um método para a preparação de uma formulação de suspoemulsão, a qual pode ser facilmente produzida em uma escala industrial e que permite a administração reproduzível e eficaz de uma ou mais drogas veterinárias insolúveis em água através de sistemas de distribuição de água. A droga veterinária insolúvel em água, na forma finamente moída, é dispersa em um líquido não-miscível em água, seguido por homogeneização deste sistema em uma fase de água. Para facilitar a preparação de uma formulação estável, um ou mais agentes de estabilização tal como emulsificantes, espessantes, antioxidantes e antimicrobianos podem ser usados. A suspoemulsão resultante mostra excelente estabilidade em armazenamento a longo prazo e em uma boa estabilidade "em uso" após diluição em um recipiente e durante todo o manuseamento e transporte no sistema de distribuição de água.
BR0013754-5A 1999-09-03 2000-08-28 Formulação veterinaria para administração de uma droga insolúvel em água a um animal alvo através de um sistema de distribuição de água BR0013754A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202876 1999-09-03
PCT/NL2000/000596 WO2001017504A1 (en) 1999-09-03 2000-08-28 Veterinary formulation for administration of a water-insoluble drug to a target animal through a water distribution system

Publications (1)

Publication Number Publication Date
BR0013754A true BR0013754A (pt) 2002-05-21

Family

ID=8240608

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013754-5A BR0013754A (pt) 1999-09-03 2000-08-28 Formulação veterinaria para administração de uma droga insolúvel em água a um animal alvo através de um sistema de distribuição de água

Country Status (35)

Country Link
US (1) US9040571B2 (pt)
EP (1) EP1214052B1 (pt)
JP (1) JP4754139B2 (pt)
KR (1) KR100702540B1 (pt)
CN (1) CN1165289C (pt)
AR (1) AR025470A1 (pt)
AT (1) ATE273000T1 (pt)
AU (1) AU775216B2 (pt)
BG (1) BG65673B1 (pt)
BR (1) BR0013754A (pt)
CA (1) CA2383164C (pt)
CZ (1) CZ301938B6 (pt)
DE (1) DE60012947T2 (pt)
EA (1) EA004785B1 (pt)
EE (1) EE05052B1 (pt)
ES (1) ES2226914T3 (pt)
HK (1) HK1049628B (pt)
HR (1) HRP20020173B1 (pt)
HU (1) HU229311B1 (pt)
IL (2) IL148438A0 (pt)
MA (1) MA25432A1 (pt)
ME (1) ME00132B (pt)
MX (1) MXPA02002360A (pt)
MY (1) MY128072A (pt)
NZ (1) NZ517024A (pt)
PL (1) PL201484B1 (pt)
PT (1) PT1214052E (pt)
RS (1) RS50341B (pt)
SI (1) SI1214052T1 (pt)
SK (1) SK285825B6 (pt)
TR (1) TR200200532T2 (pt)
TW (1) TWI234468B (pt)
UA (1) UA72933C2 (pt)
WO (1) WO2001017504A1 (pt)
ZA (1) ZA200201708B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050038022A1 (en) * 2001-03-26 2005-02-17 Unisearch Limited Method for treatment of cancer and compositions for use therein
US7893271B2 (en) 2005-07-28 2011-02-22 Intervet International B.V. Benzimidazole carbamates and (thio) carbamates, and the synthesis and use thereof
CA2660647C (en) 2006-06-14 2015-07-28 Intervet International B.V. A suspension comprising benzimidazole carbamate and a polysorbate
TWI400243B (zh) 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾（ｃｅｆｑｕｉｎｏｍｅ）粒子的方法
EP2409683A1 (en) 2010-07-06 2012-01-25 KRKA, D.D., Novo Mesto Stable aqueous formulations comprising poorly water soluble active ingredients
RU2522267C2 (ru) * 2012-08-28 2014-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Способ инкапсуляции фенбендазола
RU2522229C1 (ru) * 2013-03-26 2014-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Юго-Западный государственный университет" (ЮЗ ГУ) Способ инкапсуляции фенбендазола
RU2545742C2 (ru) * 2013-07-23 2015-04-10 Александр Александрович Кролевец Способ инкапсуляции лактобифадола
RU2555782C1 (ru) * 2014-03-03 2015-07-10 Александр Александрович Кролевец Способ получения нанокапсул сульфата глюкозамина в конжаковой камеди в гексане
RU2555055C1 (ru) * 2014-03-18 2015-07-10 Александр Александрович Кролевец Способ получения нанокапсул сульфата глюкозамина в ксантановой камеди
RU2558084C1 (ru) * 2014-03-18 2015-07-27 Александр Александрович Кролевец Способ получения нанокапсул аспирина в каррагинане
RU2557941C1 (ru) * 2014-03-20 2015-07-27 Александр Александрович Кролевец Способ получения нанокапсул аспирина в альгинате натрия
RU2554759C1 (ru) * 2014-04-07 2015-06-27 Александр Александрович Кролевец Способ получения нанокапсул лозартана калия
ES2925656T3 (es) * 2016-04-29 2022-10-19 Rousselot B V Excipiente basado en proteínas para principios farmacéuticos activos
CN110151692A (zh) * 2019-06-21 2019-08-23 石家庄九鼎动物药业有限公司 一种兽用抗寄生虫药物阿苯达唑混悬液制备方法
CN110693830B (zh) * 2019-10-10 2021-09-17 华中农业大学 一种兽用奥芬达唑纳米混悬液及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2336931A1 (fr) * 1975-12-30 1977-07-29 Dick Pierre Compositions anthelminthiques a base de benzimidazoles
US5538989A (en) * 1993-11-10 1996-07-23 Hoechst-Roussel Agri-Vet Company Fenbendazole formulations
NZ260018A (en) * 1994-03-03 1995-10-26 Bomac Lab Ltd Benzimidazole compositions and anthelmintic compositions

Also Published As

Publication number Publication date
IL148438A (en) 2006-12-10
CN1372462A (zh) 2002-10-02
JP2003508482A (ja) 2003-03-04
HRP20020173A2 (en) 2004-04-30
CZ301938B6 (cs) 2010-08-04
EA200200325A1 (ru) 2002-08-29
CA2383164A1 (en) 2001-03-15
ES2226914T3 (es) 2005-04-01
BG65673B1 (bg) 2009-06-30
ATE273000T1 (de) 2004-08-15
HUP0202686A3 (en) 2004-06-28
CA2383164C (en) 2008-07-08
EE05052B1 (et) 2008-08-15
TR200200532T2 (tr) 2002-07-22
EP1214052B1 (en) 2004-08-11
MY128072A (en) 2007-01-31
EA004785B1 (ru) 2004-08-26
KR100702540B1 (ko) 2007-04-04
DE60012947D1 (de) 2004-09-16
CZ2002630A3 (cs) 2002-09-11
MXPA02002360A (es) 2002-07-30
JP4754139B2 (ja) 2011-08-24
UA72933C2 (uk) 2005-05-16
HK1049628B (zh) 2005-05-13
ME00132B (me) 2010-10-10
HUP0202686A2 (hu) 2004-05-28
CN1165289C (zh) 2004-09-08
AU7322900A (en) 2001-04-10
SK285825B6 (sk) 2007-09-06
TWI234468B (en) 2005-06-21
MA25432A1 (fr) 2002-04-01
DE60012947T2 (de) 2005-08-25
US20090062362A1 (en) 2009-03-05
KR20020063844A (ko) 2002-08-05
HRP20020173B1 (en) 2005-02-28
EE200200094A (et) 2003-04-15
PL201484B1 (pl) 2009-04-30
WO2001017504A1 (en) 2001-03-15
PL353481A1 (en) 2003-11-17
MEP9108A (en) 2010-06-10
AU775216B2 (en) 2004-07-22
HK1049628A1 (en) 2003-05-23
RS50341B (sr) 2009-11-10
HU229311B1 (en) 2013-10-28
IL148438A0 (en) 2002-09-12
YU14302A (sh) 2004-11-25
AR025470A1 (es) 2002-11-27
US9040571B2 (en) 2015-05-26
EP1214052A1 (en) 2002-06-19
PT1214052E (pt) 2004-12-31
SI1214052T1 (en) 2005-02-28
NZ517024A (en) 2003-05-30
ZA200201708B (en) 2003-08-27
BG106448A (en) 2002-09-30
SK2642002A3 (en) 2002-12-03

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 13 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25C Requirement related to requested transfer of rights

Owner name: JANSSEN PHARMACEUTICA N.V. (BE)

Free format text: A FIM DE ATENDER A TRANSFERENCIA REQUERIDA ATRAVES DA PETICAO NO 020120000070/RJ DE 02/01/2012, E NECESSARIO COMPLEMENTAR A GUIA RELATIVA A CESSAO, BEM COMO RECOLHER A GUIA REFERENTE A ESTA EXIGENCIA.

B25B Requested transfer of rights rejected

Owner name: JANSSEN PHARMACEUTICA N.V. (BE)

Free format text: INDEFERIDO O PEDIDO DE TRANSFERENCIA CONTIDO NA PETICAO 020120000070 DE 02/01/2012, CONFORME DISPOSTO NO ART. 59 DA LEI 9279 DE 14/05/1996, PELO FATO DO PEDIDO DE PATENTE TER SIDO INDEFERIDO NA RPI 2048 DE 06/04/2010 COM DECISAO MANTIDA EM GRAU DE RECURSO PUBLICADO NA RPI 2199 DE 26/02/2013.

Owner name: JANSSEN PHARMACEUTICA N.V. (BE)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]