CN102316876A - 高剂量多拉菌素制剂 - Google Patents
高剂量多拉菌素制剂 Download PDFInfo
- Publication number
- CN102316876A CN102316876A CN2010800079297A CN201080007929A CN102316876A CN 102316876 A CN102316876 A CN 102316876A CN 2010800079297 A CN2010800079297 A CN 2010800079297A CN 201080007929 A CN201080007929 A CN 201080007929A CN 102316876 A CN102316876 A CN 102316876A
- Authority
- CN
- China
- Prior art keywords
- compositions
- vitamin
- doractin
- antiseptic
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
多拉菌素 | 3.5g |
苄醇 | 6.0mL |
生育酚乙酸酯 | 0.050g |
棉籽油 | 55.0mL |
苯甲酸苄酯q.s.p. | 100.0mL |
多拉菌素 | 3.5g |
棉籽油 | 55.0mL |
苯甲酸苄酯q.s.p. | 100.0mL |
多拉菌素 | 1.0g |
伊维菌素 | 1.0g |
苄醇 | 6.0mL |
棉籽油 | 55.0mL |
生育酚乙酸酯 | 0.050g |
苯甲酸苄酯q.s.p. | 100.0mL |
多拉菌素 | 1.0g |
伊维菌素 | 1.0g |
阿巴美丁 | 1.0g |
苄醇 | 6.0mL |
棉籽油 | 55.0mL |
生育酚乙酸酯 | 0.050g |
苯甲酸苄酯q.s.p. | 100.0mL |
药物/赋形剂 | IU/mL | |
多拉菌素 | 1.0g | na |
阿巴美丁 | 1.0g | na |
棕榈酸视黄酯(A) | 8.8g | 160000 |
维生素D3(D) | 0.1125g | 45000 |
dl-α-生育酚乙酸酯(E) | 4.5g | 45 |
BHA | 0.2g | na |
BHT | 0.2g | na |
苯甲酸苄酯q.s.p. | 25mL | na |
棉籽油 | qs 100mL | na |
Claims (15)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15291109P | 2009-02-16 | 2009-02-16 | |
US61/152,911 | 2009-02-16 | ||
US21983709P | 2009-06-24 | 2009-06-24 | |
US61/219,837 | 2009-06-24 | ||
PCT/IB2010/050443 WO2010116267A1 (en) | 2009-02-16 | 2010-02-02 | High dosage doramectin formulation |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102316876A true CN102316876A (zh) | 2012-01-11 |
CN102316876B CN102316876B (zh) | 2013-07-17 |
Family
ID=42060687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800079297A Active CN102316876B (zh) | 2009-02-16 | 2010-02-02 | 高剂量多拉菌素制剂 |
Country Status (20)
Country | Link |
---|---|
US (1) | US8551962B2 (zh) |
EP (1) | EP2396006B1 (zh) |
JP (1) | JP2012517994A (zh) |
KR (1) | KR101326428B1 (zh) |
CN (1) | CN102316876B (zh) |
AR (1) | AR075428A1 (zh) |
AU (1) | AU2010233409B2 (zh) |
BR (1) | BRPI1008822B1 (zh) |
CA (1) | CA2750626C (zh) |
CL (1) | CL2011001775A1 (zh) |
CO (1) | CO6410307A2 (zh) |
DK (1) | DK2396006T3 (zh) |
ES (1) | ES2399228T3 (zh) |
HK (1) | HK1161087A1 (zh) |
MX (1) | MX2011008614A (zh) |
NZ (1) | NZ594389A (zh) |
PL (1) | PL2396006T3 (zh) |
PT (1) | PT2396006E (zh) |
WO (1) | WO2010116267A1 (zh) |
ZA (1) | ZA201105310B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103977017A (zh) * | 2014-06-03 | 2014-08-13 | 重庆布尔动物药业有限公司 | 一种兽用抗寄生虫注射液及其制备方法 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9616044B2 (en) | 2012-03-13 | 2017-04-11 | Bayer New Zealand Ltd | Long acting compositions |
ES2436249B1 (es) * | 2012-06-25 | 2014-06-23 | Javier Alberto ALONSO-VAQUERO VELASCO | Composición antiparasitaria para el control y tratamiento de parásitos de diferentes especies animales, caracterizada por combinar Moxidectina con las vitaminas: A, D3, y E |
WO2014098623A1 (en) * | 2012-12-20 | 2014-06-26 | Alleva Animal Health Limited | Injectable eprinomectin formulation and anthelmintic use thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0393890A1 (en) * | 1989-04-11 | 1990-10-24 | Pfizer Limited | Injectable compositions containing 25-cyclohexyl-avermectin B1 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8800986A1 (es) | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
US6001822A (en) | 1989-04-11 | 1999-12-14 | Pfizer Inc. | Antiparasitic formulations |
WO1997011709A1 (en) * | 1995-09-25 | 1997-04-03 | Ashmont Holdings Limited | Anthelmintic macrocyclic lactone compositions |
DE19613972A1 (de) | 1996-04-09 | 1997-10-16 | Bayer Ag | Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl |
AU728221B2 (en) | 1996-06-05 | 2001-01-04 | Ashmont Holdings Limited | Injectable compositions |
DE19638045A1 (de) * | 1996-09-18 | 1998-03-19 | Bayer Ag | Injektionsformulierungen von Avermectinen und Milbemycinen |
US6174540B1 (en) | 1998-09-14 | 2001-01-16 | Merck & Co., Inc. | Long acting injectable formulations containing hydrogenated caster oil |
KR20000025762A (ko) * | 1998-10-14 | 2000-05-06 | 유충식 | 이버멕틴류의 가용화 조성물 |
GB9825402D0 (en) * | 1998-11-19 | 1999-01-13 | Pfizer Ltd | Antiparasitic formulations |
GB9827727D0 (en) | 1998-12-16 | 1999-02-10 | Pfizer Ltd | Antiparasitic formulations |
CN1304727A (zh) * | 2000-10-20 | 2001-07-25 | 王玉万 | 一种以苯甲酸苄酯或氮酮为助溶剂的含阿维菌素或伊维菌素的注射液 |
-
2010
- 2010-02-02 PL PL10703519T patent/PL2396006T3/pl unknown
- 2010-02-02 AU AU2010233409A patent/AU2010233409B2/en active Active
- 2010-02-02 WO PCT/IB2010/050443 patent/WO2010116267A1/en active Application Filing
- 2010-02-02 CA CA2750626A patent/CA2750626C/en not_active Expired - Fee Related
- 2010-02-02 BR BRPI1008822-9A patent/BRPI1008822B1/pt active IP Right Grant
- 2010-02-02 KR KR1020117021507A patent/KR101326428B1/ko not_active IP Right Cessation
- 2010-02-02 ES ES10703519T patent/ES2399228T3/es active Active
- 2010-02-02 CN CN2010800079297A patent/CN102316876B/zh active Active
- 2010-02-02 DK DK10703519.8T patent/DK2396006T3/da active
- 2010-02-02 EP EP10703519A patent/EP2396006B1/en not_active Not-in-force
- 2010-02-02 PT PT107035198T patent/PT2396006E/pt unknown
- 2010-02-02 NZ NZ594389A patent/NZ594389A/xx not_active IP Right Cessation
- 2010-02-02 MX MX2011008614A patent/MX2011008614A/es active IP Right Grant
- 2010-02-02 JP JP2011549707A patent/JP2012517994A/ja active Pending
- 2010-02-02 US US13/147,600 patent/US8551962B2/en not_active Expired - Fee Related
- 2010-02-15 AR ARP100100431A patent/AR075428A1/es active IP Right Grant
-
2011
- 2011-07-19 ZA ZA2011/05310A patent/ZA201105310B/en unknown
- 2011-07-21 CL CL2011001775A patent/CL2011001775A1/es unknown
- 2011-08-30 CO CO11111108A patent/CO6410307A2/es not_active Application Discontinuation
-
2012
- 2012-02-16 HK HK12101546.3A patent/HK1161087A1/xx not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0393890A1 (en) * | 1989-04-11 | 1990-10-24 | Pfizer Limited | Injectable compositions containing 25-cyclohexyl-avermectin B1 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103977017A (zh) * | 2014-06-03 | 2014-08-13 | 重庆布尔动物药业有限公司 | 一种兽用抗寄生虫注射液及其制备方法 |
CN103977017B (zh) * | 2014-06-03 | 2016-09-07 | 重庆布尔动物药业有限公司 | 一种兽用抗寄生虫注射液及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
EP2396006A1 (en) | 2011-12-21 |
NZ594389A (en) | 2012-09-28 |
ES2399228T3 (es) | 2013-03-26 |
US20110294751A1 (en) | 2011-12-01 |
PL2396006T3 (pl) | 2013-06-28 |
KR20110116231A (ko) | 2011-10-25 |
CA2750626A1 (en) | 2010-10-14 |
US8551962B2 (en) | 2013-10-08 |
HK1161087A1 (en) | 2012-08-24 |
AR075428A1 (es) | 2011-03-30 |
BRPI1008822B1 (pt) | 2019-04-09 |
CN102316876B (zh) | 2013-07-17 |
CO6410307A2 (es) | 2012-03-30 |
CL2011001775A1 (es) | 2011-10-28 |
DK2396006T3 (da) | 2013-02-11 |
WO2010116267A1 (en) | 2010-10-14 |
PT2396006E (pt) | 2013-02-13 |
CA2750626C (en) | 2013-10-01 |
AU2010233409B2 (en) | 2012-05-17 |
AU2010233409A1 (en) | 2011-08-11 |
EP2396006B1 (en) | 2012-12-19 |
JP2012517994A (ja) | 2012-08-09 |
KR101326428B1 (ko) | 2013-11-20 |
ZA201105310B (en) | 2012-09-26 |
MX2011008614A (es) | 2011-09-09 |
BRPI1008822A2 (pt) | 2016-03-08 |
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