BR0006909A - Sequências de nucleotìdeos que codificam o gene de opca - Google Patents
Sequências de nucleotìdeos que codificam o gene de opcaInfo
- Publication number
- BR0006909A BR0006909A BR0006909-4A BR0006909A BR0006909A BR 0006909 A BR0006909 A BR 0006909A BR 0006909 A BR0006909 A BR 0006909A BR 0006909 A BR0006909 A BR 0006909A
- Authority
- BR
- Brazil
- Prior art keywords
- seq
- polynucleotide
- gene
- amino acid
- nucleotide sequences
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 9
- 239000002157 polynucleotide Substances 0.000 abstract 9
- 102000040430 polynucleotide Human genes 0.000 abstract 9
- 150000008575 L-amino acids Chemical class 0.000 abstract 4
- 150000001413 amino acids Chemical group 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 230000003321 amplification Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 101150110333 opcA gene Proteins 0.000 abstract 1
- 101150104606 pgl gene Proteins 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 108700004027 tat Genes Proteins 0.000 abstract 1
- 101150098170 tat gene Proteins 0.000 abstract 1
- 101150078419 zwf gene Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Patente de Invenção: <B>"SEQUêNCIAS DE NUCLEOTìDEOS QUE CODIFICAM O GENE DE OPCA"<D>. A invenção refere-se a um polinucleotídeo isolado de bactérias corinoformes, compreendendo pelo menos uma sequência de polinucleotídeos escolhida do grupo que consiste em a) polinucleotídeo que é idêntico na extensão de pelo menos 70% a um polinucleotídeo que codifica polipeptídeos que compreendem pelo menos uma das sequências de aminoácidos de acordo com SEQ ID NO: 3 ou SEQ ID NO: 5 ou SEQ ID NO: 8 ou SEQ ID NO: 10, b) polinucleotídeo que codifica polipeptídeos que compreendem sequências de aminoácidos que são idênticas na extensão de pelo menos 70% às sequências de aminoácidos de acordo com SEQ ID NO: 3 ou SEQ ID NO: 5 ou de acordo com SEQ ID NO: 8 ou SEQ ID NO: 10, c) polinucleotídeo que é complementar aos polinucleotídeos de a) ou b), ou d) polinucleotídeo compreendendo pelo menos 15 nucleotídeos sucessivos das sequências de polinucleotídeos de a), b) ou c) e um processo para a preparação fermentativa de L-aminóacidos, que compreende nos microorganismos corinoformes que em particular já produzem L-aminoácidos, a) ampliação, em particular ultra-expressão, além do gene de opcA, pelo menos uma das sequências de nucleotídeos que codificam o gene de tat, gene de tkl, gene de zwf ou o gene de devB, b) concentração do L-aminoácido desejado no meio ou nas células das bactérias e c) isolamento do L-aminoácido.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14291599P | 1999-07-09 | 1999-07-09 | |
| US53126700A | 2000-03-20 | 2000-03-20 | |
| PCT/EP2000/006300 WO2001004322A1 (en) | 1999-07-09 | 2000-07-05 | Nucleotide sequences which code for the opca gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0006909A true BR0006909A (pt) | 2001-06-12 |
Family
ID=26840529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0006909-4A BR0006909A (pt) | 1999-07-09 | 2000-07-05 | Sequências de nucleotìdeos que codificam o gene de opca |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6825029B2 (pt) |
| EP (1) | EP1109913B1 (pt) |
| JP (1) | JP2003504065A (pt) |
| KR (1) | KR100731525B1 (pt) |
| CN (1) | CN100352926C (pt) |
| AT (1) | ATE338131T1 (pt) |
| AU (1) | AU772563B2 (pt) |
| BR (1) | BR0006909A (pt) |
| CA (1) | CA2348365A1 (pt) |
| DE (1) | DE60030400T2 (pt) |
| DK (1) | DK1109913T3 (pt) |
| HU (1) | HUP0104068A3 (pt) |
| ID (1) | ID29569A (pt) |
| MX (1) | MX240992B (pt) |
| PL (1) | PL206384B1 (pt) |
| SK (1) | SK3012001A3 (pt) |
| WO (1) | WO2001004322A1 (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI9813021B1 (pt) * | 1997-10-04 | 2016-04-05 | Degussa | processo para a preparação microbiana de aminoácidos de l-lisina, l-treonina, l-homosserina e glutamato, vetor, e célula transformada |
| US6822084B1 (en) * | 1999-06-25 | 2004-11-23 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins |
| US7270984B1 (en) * | 1999-06-25 | 2007-09-18 | Basf Aktiengesellschaft | Polynucleotides encoding a 6-phosphogluconolactonase polypeptide from corynebacterium glutamicum |
| US6797509B1 (en) * | 1999-07-09 | 2004-09-28 | Degussa-Huls Ag | Nucleotide sequences which code for the tal gene |
| US20060014259A9 (en) * | 1999-07-09 | 2006-01-19 | Kevin Burke | Process for the preparation of L-amino acids with amplification of the zwf gene |
| DE19947791A1 (de) * | 1999-10-05 | 2001-04-12 | Degussa | Neue für das eno-Gen codierende Nukleotidsequenzen |
| US6713289B2 (en) | 1999-10-05 | 2004-03-30 | Degussa Ag | Nucleotide sequences which code for the eno gene |
| BR0010817A (pt) * | 2000-03-20 | 2002-03-05 | Degussa | Processo para a preparação fermentativa de l-aminoácidos com amplificação do gene gnd |
| US20050112733A1 (en) * | 2000-03-20 | 2005-05-26 | Degussa Ag | Process for the preparation of L-amino acids with amplification of the zwf gene |
| ATE461997T1 (de) | 2000-06-21 | 2010-04-15 | Kyowa Hakko Bio Co Ltd | Neuartige glukose-6-phosphat dehydrogenase |
| US20030017554A1 (en) * | 2000-11-15 | 2003-01-23 | Mechthild Rieping | Process for the fermentative preparation of L-amino acids using strains of the enterobacteriaceae family |
| DE10154180A1 (de) * | 2001-11-05 | 2003-05-15 | Basf Ag | gene die für genetische Stabilitäts-, genexpressions-und Faltungsproteine codieren |
| DE10155505A1 (de) * | 2001-11-13 | 2003-05-22 | Basf Ag | Gene die für Glucose-6-Phosphat-Dehydrogenase Proteine codieren |
| DE10210527A1 (de) | 2002-03-09 | 2003-09-18 | Degussa | Allele des aceA-Gens aus coryneformen Bakterien |
| US20070092951A1 (en) * | 2005-03-24 | 2007-04-26 | Degussa Ag | Alleles of the zwf gene from coryneform bacteria |
| DE102005023829A1 (de) | 2005-05-24 | 2006-11-30 | Degussa Ag | Allele des opcA-Gens aus coryneformen Bakterien |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| CN102482649B (zh) * | 2009-06-23 | 2014-09-03 | 江南大学 | 立体专一性羰基还原酶 |
| CN104845923B (zh) * | 2014-02-14 | 2018-03-23 | 中国科学院微生物研究所 | 生产l‑组氨酸的方法及其专用重组菌 |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| BR112020018947B1 (pt) | 2018-03-23 | 2023-05-02 | Cj Cheiljedang Corporation | Grânulos que compreendem l-aminoácido e método para preparar os mesmos |
| WO2020051420A1 (en) | 2018-09-07 | 2020-03-12 | Archer Daniels Midland Company | Engineered strains of corynebacteria |
| CN116254242B (zh) * | 2022-12-21 | 2024-01-30 | 江南大学 | 一种atp磷酸核苷转移酶突变体及产l-组氨酸的谷氨酸棒杆菌 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07121227B2 (ja) * | 1986-10-17 | 1995-12-25 | 協和醗酵工業株式会社 | Ｌ−グルタミン酸の製造法 |
| JP3336162B2 (ja) * | 1995-07-11 | 2002-10-21 | 株式会社リコー | デジタル複写機のネットワークシステム |
| JPH09224661A (ja) * | 1996-02-23 | 1997-09-02 | Mitsubishi Chem Corp | グルコース−６−リン酸デヒドロゲナーゼおよびそれをコードするｄｎａ |
| KR20070087093A (ko) | 1999-06-25 | 2007-08-27 | 바스프 악티엔게젤샤프트 | 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자 |
| US6962989B1 (en) * | 1999-07-08 | 2005-11-08 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding novel proteins |
| JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
-
2000
- 2000-07-05 ID IDW20010559A patent/ID29569A/id unknown
- 2000-07-05 DK DK00945874T patent/DK1109913T3/da active
- 2000-07-05 MX MXPA01002410 patent/MX240992B/es active IP Right Grant
- 2000-07-05 EP EP00945874A patent/EP1109913B1/en not_active Expired - Lifetime
- 2000-07-05 CA CA002348365A patent/CA2348365A1/en not_active Abandoned
- 2000-07-05 AT AT00945874T patent/ATE338131T1/de not_active IP Right Cessation
- 2000-07-05 KR KR1020017003075A patent/KR100731525B1/ko not_active IP Right Cessation
- 2000-07-05 JP JP2001509526A patent/JP2003504065A/ja active Pending
- 2000-07-05 WO PCT/EP2000/006300 patent/WO2001004322A1/en active IP Right Grant
- 2000-07-05 CN CNB008013349A patent/CN100352926C/zh not_active Expired - Fee Related
- 2000-07-05 SK SK301-2001A patent/SK3012001A3/sk unknown
- 2000-07-05 HU HU0104068A patent/HUP0104068A3/hu unknown
- 2000-07-05 PL PL346563A patent/PL206384B1/pl unknown
- 2000-07-05 DE DE60030400T patent/DE60030400T2/de not_active Expired - Lifetime
- 2000-07-05 BR BR0006909-4A patent/BR0006909A/pt not_active Application Discontinuation
- 2000-07-05 AU AU59821/00A patent/AU772563B2/en not_active Ceased
-
2002
- 2002-05-03 US US10/137,655 patent/US6825029B2/en not_active Expired - Lifetime
-
2004
- 2004-11-01 US US10/976,768 patent/US7504242B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0104068A2 (hu) | 2002-03-28 |
| EP1109913B1 (en) | 2006-08-30 |
| CA2348365A1 (en) | 2001-01-18 |
| AU5982100A (en) | 2001-01-30 |
| US7504242B2 (en) | 2009-03-17 |
| PL206384B1 (pl) | 2010-08-31 |
| DE60030400D1 (de) | 2006-10-12 |
| KR20010086398A (ko) | 2001-09-10 |
| SK3012001A3 (en) | 2002-07-02 |
| US6825029B2 (en) | 2004-11-30 |
| CN100352926C (zh) | 2007-12-05 |
| WO2001004322A9 (en) | 2002-09-12 |
| EP1109913A1 (en) | 2001-06-27 |
| AU772563B2 (en) | 2004-04-29 |
| CN1317049A (zh) | 2001-10-10 |
| MXPA01002410A (es) | 2003-09-10 |
| HUP0104068A3 (en) | 2003-09-29 |
| DK1109913T3 (da) | 2007-01-02 |
| ATE338131T1 (de) | 2006-09-15 |
| US20030138917A1 (en) | 2003-07-24 |
| US20050112730A1 (en) | 2005-05-26 |
| PL346563A1 (en) | 2002-02-11 |
| ID29569A (id) | 2001-09-06 |
| DE60030400T2 (de) | 2007-09-13 |
| JP2003504065A (ja) | 2003-02-04 |
| WO2001004322A1 (en) | 2001-01-18 |
| MX240992B (es) | 2006-10-10 |
| KR100731525B1 (ko) | 2007-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |