BR0005092A - Sequências de nucleotìdeo codificando a exportação de aminoácidos de cadeia ramificada, processo para isolamento e uso dos mesmos - Google Patents
Sequências de nucleotìdeo codificando a exportação de aminoácidos de cadeia ramificada, processo para isolamento e uso dos mesmosInfo
- Publication number
- BR0005092A BR0005092A BR0005092-0A BR0005092A BR0005092A BR 0005092 A BR0005092 A BR 0005092A BR 0005092 A BR0005092 A BR 0005092A BR 0005092 A BR0005092 A BR 0005092A
- Authority
- BR
- Brazil
- Prior art keywords
- polynucleotide
- amino acids
- export
- isolation
- branched chain
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000005693 branched-chain amino acids Chemical class 0.000 title abstract 2
- 238000002955 isolation Methods 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 abstract 9
- 102000040430 polynucleotide Human genes 0.000 abstract 9
- 108091033319 polynucleotide Proteins 0.000 abstract 9
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 150000008575 L-amino acids Chemical class 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Patente de Invenção: <B>"SEQuêNCIAS DE NUCLEOTìDEO CODIFICANDO A EXPORTAçãO DE AMINOáCIDOS DE CADEIA RAMIFICADA, PROCESSO PARA ISOLAMENTO E USO DOS MESMOS"<D>. Esta invenção refere-se aos polinucleotídeos isolados contendo, pelo menos, uma das seq³ências de polinucleotídeos selecionadas do grupo: a) polinucleotídeo que é pelo menos 70% idêntico ao polinucleotídeo que codifica um polipeptídeo contendo, pelo menos, uma seq³ência de aminoácido SEQ ID n° 3 ou 5, b) polinucleotídeo que codifica um polipeptídeo que contém uma seq³ência de aminoácido que é pelo menos 70% idêntica à seq³ência de aminoácido da SEQ ID n° 3 ou 5, c) polinucleotídeo que é complementar aos polinucleotídeos de a), b) ou c), e d) polinucleotídeo contendo pelo menos 15 bases sucessivas das seq³ências de polinucleotídeo de a), b) ou c) onde os polipeptídeos exibem atividade biológica das enzimas para as quais o gene brnE ou brnF condifica e um processo para produção fermentativa de L-aminoácidos de cadeia ramificada com ampliação dos genes citados.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19951708A DE19951708A1 (de) | 1999-10-27 | 1999-10-27 | Für den Export verzweigtkettiger Aminosäuren kodierende Nikleotidsequenzen, Verfahren zu deren Isolierung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0005092A true BR0005092A (pt) | 2001-06-19 |
Family
ID=7927025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0005092-0A BR0005092A (pt) | 1999-10-27 | 2000-10-27 | Sequências de nucleotìdeo codificando a exportação de aminoácidos de cadeia ramificada, processo para isolamento e uso dos mesmos |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6613545B1 (pt) |
| EP (1) | EP1096010B1 (pt) |
| JP (1) | JP2001169788A (pt) |
| KR (1) | KR20010051233A (pt) |
| CN (1) | CN1302873A (pt) |
| AT (1) | ATE481489T1 (pt) |
| AU (1) | AU6542600A (pt) |
| BR (1) | BR0005092A (pt) |
| CA (1) | CA2321975A1 (pt) |
| DE (2) | DE19951708A1 (pt) |
| ES (1) | ES2352183T3 (pt) |
| HU (1) | HUP0004168A2 (pt) |
| ID (1) | ID27957A (pt) |
| MX (1) | MXPA00010420A (pt) |
| PL (1) | PL343541A1 (pt) |
| SK (1) | SK15742000A3 (pt) |
| ZA (1) | ZA200006041B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6480510B1 (en) * | 1998-07-28 | 2002-11-12 | Serconet Ltd. | Local area network of serial intelligent cells |
| ES2331956T3 (es) | 2004-01-30 | 2010-01-21 | Ajinomoto Co., Inc. | Microorganismo que produce l-aminoacidos y procedimiento para producir l-aminoacidos. |
| BRPI0611909A2 (pt) * | 2005-06-17 | 2009-01-20 | Microbia Inc | biossÍntese aperfeiÇoada de aminoÁcido e metabàlito |
| EP1801117A1 (en) * | 2005-12-21 | 2007-06-27 | Friesland Brands B.V. | Means and methods for regulating amino acid pools and/or transport |
| JP2010017082A (ja) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| KR100832740B1 (ko) | 2007-01-17 | 2008-05-27 | 한국과학기술원 | 분지쇄 아미노산 생성능이 개선된 변이 미생물 및 이를이용한 분지쇄 아미노산의 제조방법 |
| JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | Ｌ−アミノ酸または核酸の製造方法 |
| JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| EP2248906A4 (en) | 2008-01-23 | 2012-07-11 | Ajinomoto Kk | PROCESS FOR THE PREPARATION OF L-AMINO ACID |
| EP2460883A4 (en) | 2009-07-29 | 2013-01-16 | Ajinomoto Kk | PROCESS FOR THE PREPARATION OF L-AMINO ACID |
| WO2014185430A1 (ja) | 2013-05-13 | 2014-11-20 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| HUE032752T2 (en) * | 2013-06-03 | 2017-10-30 | Evonik Degussa Gmbh | A method for the preparation of L-valine using recombinant corynebacteria containing propionate-inducible ilvBN operon |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| BR112016007286B1 (pt) | 2013-10-02 | 2021-07-20 | Ajinomoto Co., Inc | Métodos de controle de amônia e para produção de uma substância alvo, e, aparelho para controle de amônia |
| JP6519476B2 (ja) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | 目的物質の製造法 |
| CN105907692A (zh) * | 2016-04-27 | 2016-08-31 | 齐鲁工业大学 | 一种高产l-赖氨酸的重组谷氨酸棒状杆菌及其构建方法 |
| JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| KR20220092182A (ko) * | 2020-12-24 | 2022-07-01 | 씨제이제일제당 (주) | L-히스티딘 배출 단백질 및 이를 이용한 l-히스티딘 생산 방법 |
| CN117106042A (zh) * | 2021-08-23 | 2023-11-24 | 黑龙江伊品生物科技有限公司 | Yh66-rs07020突变体蛋白及其相关生物材料在制备缬氨酸中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19548222A1 (de) | 1995-12-22 | 1997-06-26 | Forschungszentrum Juelich Gmbh | Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern |
| DE19947792A1 (de) * | 1999-10-05 | 2001-04-12 | Degussa | Neue für das Irp Gen codierende Nukleotidsequenzen |
| JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
-
1999
- 1999-10-27 DE DE19951708A patent/DE19951708A1/de not_active Withdrawn
- 1999-12-23 US US09/471,803 patent/US6613545B1/en not_active Expired - Lifetime
-
2000
- 2000-10-11 ES ES00122057T patent/ES2352183T3/es not_active Expired - Lifetime
- 2000-10-11 DE DE50015992T patent/DE50015992D1/de not_active Expired - Lifetime
- 2000-10-11 AT AT00122057T patent/ATE481489T1/de active
- 2000-10-11 AU AU65426/00A patent/AU6542600A/en not_active Abandoned
- 2000-10-11 EP EP00122057A patent/EP1096010B1/de not_active Expired - Lifetime
- 2000-10-20 ID IDP20000904D patent/ID27957A/id unknown
- 2000-10-20 SK SK1574-2000A patent/SK15742000A3/sk unknown
- 2000-10-24 JP JP2000324315A patent/JP2001169788A/ja active Pending
- 2000-10-24 MX MXPA00010420A patent/MXPA00010420A/es unknown
- 2000-10-24 CN CN00129891A patent/CN1302873A/zh active Pending
- 2000-10-25 KR KR1020000062857A patent/KR20010051233A/ko not_active Application Discontinuation
- 2000-10-25 CA CA002321975A patent/CA2321975A1/en not_active Abandoned
- 2000-10-26 ZA ZA200006041A patent/ZA200006041B/xx unknown
- 2000-10-26 HU HU0004168A patent/HUP0004168A2/hu unknown
- 2000-10-27 BR BR0005092-0A patent/BR0005092A/pt not_active Application Discontinuation
- 2000-10-27 PL PL00343541A patent/PL343541A1/xx unknown
-
2003
- 2003-06-30 US US10/608,504 patent/US6841360B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200006041B (en) | 2001-05-18 |
| AU6542600A (en) | 2001-05-03 |
| US6613545B1 (en) | 2003-09-02 |
| CN1302873A (zh) | 2001-07-11 |
| DE19951708A1 (de) | 2001-05-03 |
| SK15742000A3 (sk) | 2001-12-03 |
| US6841360B2 (en) | 2005-01-11 |
| PL343541A1 (en) | 2001-05-07 |
| KR20010051233A (ko) | 2001-06-25 |
| JP2001169788A (ja) | 2001-06-26 |
| ATE481489T1 (de) | 2010-10-15 |
| MXPA00010420A (es) | 2002-06-04 |
| HUP0004168A2 (en) | 2002-09-28 |
| CA2321975A1 (en) | 2001-04-27 |
| EP1096010B1 (de) | 2010-09-15 |
| US20040014123A1 (en) | 2004-01-22 |
| ID27957A (id) | 2001-05-03 |
| ES2352183T3 (es) | 2011-02-16 |
| DE50015992D1 (de) | 2010-10-28 |
| EP1096010A1 (de) | 2001-05-02 |
| HU0004168D0 (pt) | 2001-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |