BR0004208A - Sequências de nucleotìdeos codificando gene pgi - Google Patents
Sequências de nucleotìdeos codificando gene pgiInfo
- Publication number
- BR0004208A BR0004208A BR0004208-0A BR0004208A BR0004208A BR 0004208 A BR0004208 A BR 0004208A BR 0004208 A BR0004208 A BR 0004208A BR 0004208 A BR0004208 A BR 0004208A
- Authority
- BR
- Brazil
- Prior art keywords
- polynucleotide
- nucleotide sequences
- pgi gene
- sequences encoding
- amino acid
- Prior art date
Links
- 101150053253 pgi gene Proteins 0.000 title abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 9
- 239000002157 polynucleotide Substances 0.000 abstract 9
- 102000040430 polynucleotide Human genes 0.000 abstract 9
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 150000002972 pentoses Chemical class 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
- C12Y503/01009—Glucose-6-phosphate isomerase (5.3.1.9)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Patente de Invenção: <B>"SEQuêNCIAS DE NUCLEOTìDEOS CODIFICANDO GENE PGI"<D>. Polinucleotídeo isolado contendo uma seq³ência de polinucleotídeos selecionada do grupo a) polinucleotídeo que é pelo menos 70% idêntico a um polinucleotídeo que codifica um polipeptídio contendo a seq³ência de aminoácidos de SEQ ID NO:2, b) polinucleotídeo que codifica um polipeptídio que contém uma seq³ência de aminoácidos que é pelo menos 70% idêntica à seq³ência de aminoácidos de SEQ ID NO:2, c) polinucleotídeo que é complementar aos polinucleotídeos de a) ou b), e d) polinucleotídeos contendo pelo menos 15 bases sucessivas da seq³ência de polinucleotídeos de a), b) ou c), e processo para aumento de fluxo metabólico através de ciclo pentose fosfato através de atenuação de gene pgi.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/396,478 US6586214B1 (en) | 1999-09-15 | 1999-09-15 | Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene) |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0004208A true BR0004208A (pt) | 2001-04-10 |
Family
ID=23567336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0004208-0A BR0004208A (pt) | 1999-09-15 | 2000-09-15 | Sequências de nucleotìdeos codificando gene pgi |
Country Status (16)
Country | Link |
---|---|
US (1) | US6586214B1 (pt) |
EP (1) | EP1087015B1 (pt) |
JP (1) | JP2001136988A (pt) |
KR (1) | KR20010050449A (pt) |
CN (1) | CN1288058A (pt) |
AT (1) | ATE486942T1 (pt) |
AU (1) | AU5505500A (pt) |
BR (1) | BR0004208A (pt) |
CA (1) | CA2318507A1 (pt) |
DE (1) | DE60045180D1 (pt) |
HU (1) | HUP0003651A3 (pt) |
ID (1) | ID27238A (pt) |
MX (1) | MXPA00008965A (pt) |
RU (1) | RU2261912C2 (pt) |
SK (1) | SK13362000A3 (pt) |
ZA (1) | ZA200004911B (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20070087093A (ko) * | 1999-06-25 | 2007-08-27 | 바스프 악티엔게젤샤프트 | 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자 |
CA2377693C (en) * | 1999-07-23 | 2016-11-08 | Archer-Daniels-Midland Company | Methods for producing l-amino acids |
US6586214B1 (en) * | 1999-09-15 | 2003-07-01 | Degussa Ag | Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene) |
US6818432B2 (en) | 2000-01-13 | 2004-11-16 | Degussa Ag | Nucleotide sequences encoding the ptsH gene |
US20030175911A1 (en) * | 2000-03-20 | 2003-09-18 | Stephen Hans | Process for the preparation of L-amino acids with amplification of the zwf gene |
US20050112733A1 (en) * | 2000-03-20 | 2005-05-26 | Degussa Ag | Process for the preparation of L-amino acids with amplification of the zwf gene |
EP1174520A3 (en) * | 2000-07-18 | 2004-02-18 | Degussa AG | Method for monitoring a fermentation process using an expression array |
US20030017554A1 (en) * | 2000-11-15 | 2003-01-23 | Mechthild Rieping | Process for the fermentative preparation of L-amino acids using strains of the enterobacteriaceae family |
JP2005510999A (ja) | 2001-04-04 | 2005-04-28 | ジェネンコー・インターナショナル・インク | 宿主細胞における生成物の生産方法 |
US7241587B2 (en) * | 2001-04-04 | 2007-07-10 | Genencor International, Inc. | Method of uncoupling the catabolic pathway of glycolysis from the oxidative membrane bound pathway of glucose conversion |
CA2462641A1 (en) * | 2001-10-01 | 2003-04-10 | Diversa Corporation | Whole cell engineering using real-time metabolic flux analysis |
DE10163167A1 (de) * | 2001-12-21 | 2003-07-03 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren und Verwendung coryneformer Bakterien |
DE10220574A1 (de) * | 2002-05-08 | 2003-11-20 | Degussa | Verfahren zur Herstellung von Aminosäuren mit coryneformen Bakterien unter Verwendung von Phosphoglucose-Isomerasen aus coryneformen Bakterien |
WO2005059139A2 (en) * | 2003-12-18 | 2005-06-30 | Basf Aktiengesellschaft | Methods for the preparation of lysine by fermentation of corynebacterium glutamicum |
US20050181488A1 (en) * | 2004-02-12 | 2005-08-18 | Akhverdian Valery Z. | Method for producing L-threonine using bacteria belonging to the genus Escherichia |
DE102005013676A1 (de) | 2005-03-24 | 2006-09-28 | Degussa Ag | Allele des zwf-Gens aus coryneformen Bakterien |
US20070092951A1 (en) * | 2005-03-24 | 2007-04-26 | Degussa Ag | Alleles of the zwf gene from coryneform bacteria |
DE102005023829A1 (de) | 2005-05-24 | 2006-11-30 | Degussa Ag | Allele des opcA-Gens aus coryneformen Bakterien |
RU2396336C2 (ru) * | 2007-09-27 | 2010-08-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia |
KR101049023B1 (ko) | 2008-03-05 | 2011-07-12 | 씨제이제일제당 (주) | 5'-이노신산 생산능이 향상된 코리네박테리움암모니아게네스 및 그를 이용한 5'-이노신산의 생산방법 |
US7821360B2 (en) * | 2008-08-28 | 2010-10-26 | Northrop Grumman Systems Corporation | Multi-channel surface acoustic wave filter device with voltage controlled tunable frequency response |
KR101166027B1 (ko) | 2009-04-01 | 2012-07-19 | 씨제이제일제당 (주) | 5'-이노신산 생산성이 향상된 코리네박테리움 속 미생물 및 이를 이용한 핵산의 생산방법 |
DE102011006716A1 (de) * | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung |
CN104845923B (zh) | 2014-02-14 | 2018-03-23 | 中国科学院微生物研究所 | 生产l‑组氨酸的方法及其专用重组菌 |
CA3007635A1 (en) | 2015-12-07 | 2017-06-15 | Zymergen Inc. | Promoters from corynebacterium glutamicum |
US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
KR102345898B1 (ko) | 2016-06-30 | 2022-01-03 | 지머젠 인코포레이티드 | 글루코오스 투과 효소 라이브러리를 생성하는 방법 및 이의 용도 |
WO2018005655A2 (en) | 2016-06-30 | 2018-01-04 | Zymergen Inc. | Methods for generating a bacterial hemoglobin library and uses thereof |
KR20200026881A (ko) | 2017-06-07 | 2020-03-11 | 지머젠 인코포레이티드 | 코리네박테리움 글루타미컴으로부터의 프로모터 및 보조 유전자 발현을 조절하는 데 이의 용도 |
CN109423504B (zh) * | 2017-08-24 | 2022-10-04 | 廊坊梅花生物技术开发有限公司 | 生产l-色氨酸的菌株及用途 |
EP3824093A4 (en) * | 2018-07-16 | 2022-06-01 | Manus Bio, Inc. | PRODUCTION OF STEVIOL GLYCOSIDES BY WHOLE-CELL BIOTRANSFORMATION |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58126789A (ja) | 1981-12-29 | 1983-07-28 | Kyowa Hakko Kogyo Co Ltd | レースレオニンの製造法 |
JP3369231B2 (ja) * | 1992-12-03 | 2003-01-20 | 協和醗酵工業株式会社 | 芳香族アミノ酸の製造法 |
KR20070087093A (ko) | 1999-06-25 | 2007-08-27 | 바스프 악티엔게젤샤프트 | 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자 |
CA2377693C (en) | 1999-07-23 | 2016-11-08 | Archer-Daniels-Midland Company | Methods for producing l-amino acids |
US6586214B1 (en) * | 1999-09-15 | 2003-07-01 | Degussa Ag | Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene) |
JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
PL205611B1 (pl) * | 2000-03-20 | 2010-05-31 | Degussa | Wyizolowany gen zwf z Corynebacterium glutamicum, rekombinowana bakteria coryneform wytwarzająca L-lizynę lub L-treoninę oraz sposób wytwarzania L-lizyny lub L-treoniny przez fermentację bakterii |
-
1999
- 1999-09-15 US US09/396,478 patent/US6586214B1/en not_active Expired - Lifetime
-
2000
- 2000-08-23 DE DE60045180T patent/DE60045180D1/de not_active Expired - Lifetime
- 2000-08-23 AT AT00118052T patent/ATE486942T1/de active
- 2000-08-23 EP EP00118052A patent/EP1087015B1/en not_active Expired - Lifetime
- 2000-09-01 AU AU55055/00A patent/AU5505500A/en not_active Abandoned
- 2000-09-08 SK SK1336-2000A patent/SK13362000A3/sk unknown
- 2000-09-12 ID IDP20000772D patent/ID27238A/id unknown
- 2000-09-13 CA CA002318507A patent/CA2318507A1/en not_active Abandoned
- 2000-09-13 MX MXPA00008965A patent/MXPA00008965A/es unknown
- 2000-09-14 HU HU0003651A patent/HUP0003651A3/hu unknown
- 2000-09-14 KR KR1020000054019A patent/KR20010050449A/ko not_active Application Discontinuation
- 2000-09-14 ZA ZA200004911A patent/ZA200004911B/xx unknown
- 2000-09-15 CN CN00124519A patent/CN1288058A/zh active Pending
- 2000-09-15 RU RU2000123636/13A patent/RU2261912C2/ru not_active IP Right Cessation
- 2000-09-15 BR BR0004208-0A patent/BR0004208A/pt not_active IP Right Cessation
- 2000-09-18 JP JP2000282681A patent/JP2001136988A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE60045180D1 (de) | 2010-12-16 |
ATE486942T1 (de) | 2010-11-15 |
EP1087015A2 (en) | 2001-03-28 |
CN1288058A (zh) | 2001-03-21 |
RU2261912C2 (ru) | 2005-10-10 |
JP2001136988A (ja) | 2001-05-22 |
ZA200004911B (en) | 2002-03-13 |
HUP0003651A3 (en) | 2005-07-28 |
EP1087015A3 (en) | 2003-07-09 |
HUP0003651A2 (hu) | 2003-04-28 |
MXPA00008965A (es) | 2002-12-16 |
US6586214B1 (en) | 2003-07-01 |
KR20010050449A (ko) | 2001-06-15 |
EP1087015B1 (en) | 2010-11-03 |
SK13362000A3 (sk) | 2003-01-09 |
CA2318507A1 (en) | 2001-03-15 |
AU5505500A (en) | 2001-03-22 |
ID27238A (id) | 2001-03-15 |
HU0003651D0 (en) | 2000-09-14 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |