BG99594A - Метод за получаване на енантиомерно чист 6-/(4-хлорофенил)- (1н-1,2,4-триазол-1-ил)метил/-1-метил-1н-бензотриазол, междинни продукти и методи за получаването им - Google Patents
Метод за получаване на енантиомерно чист 6-/(4-хлорофенил)- (1н-1,2,4-триазол-1-ил)метил/-1-метил-1н-бензотриазол, междинни продукти и методи за получаването им Download PDFInfo
- Publication number
- BG99594A BG99594A BG99594A BG9959495A BG99594A BG 99594 A BG99594 A BG 99594A BG 99594 A BG99594 A BG 99594A BG 9959495 A BG9959495 A BG 9959495A BG 99594 A BG99594 A BG 99594A
- Authority
- BG
- Bulgaria
- Prior art keywords
- formula
- acid
- reaction
- product
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92203443 | 1992-11-10 | ||
| PCT/EP1993/003066 WO1994011364A1 (en) | 1992-11-10 | 1993-11-02 | Process for preparing enantiomerically pure 6-[(4-chlorophenyl)(1h^_-triazol-1,2,4-triazol-1-yl)methyl]-1-methyl-1h^_-benzotriazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG99594A true BG99594A (bg) | 1996-01-31 |
Family
ID=8211029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG99594A BG99594A (bg) | 1992-11-10 | 1995-04-20 | Метод за получаване на енантиомерно чист 6-/(4-хлорофенил)- (1н-1,2,4-триазол-1-ил)метил/-1-метил-1н-бензотриазол, междинни продукти и методи за получаването им |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5663354A (ro) |
| EP (1) | EP0668861A1 (ro) |
| JP (1) | JPH08502990A (ro) |
| AU (1) | AU679704B2 (ro) |
| BG (1) | BG99594A (ro) |
| BR (1) | BR9307409A (ro) |
| CA (1) | CA2148489A1 (ro) |
| CZ (1) | CZ115195A3 (ro) |
| FI (1) | FI952251A (ro) |
| HU (1) | HUT72073A (ro) |
| NO (1) | NO951808L (ro) |
| NZ (1) | NZ257551A (ro) |
| PL (1) | PL176059B1 (ro) |
| RO (1) | RO114327B1 (ro) |
| RU (1) | RU95112576A (ro) |
| SG (1) | SG50476A1 (ro) |
| SK (1) | SK59995A3 (ro) |
| WO (1) | WO1994011364A1 (ro) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ257551A (en) * | 1992-11-10 | 1995-10-26 | Janssen Pharmaceutica Nv | Preparation of 6-[(4-chlorophenyl)(1h-1,2,4-triazol-1-yl)methyl]-1-methyl-1h-benzotriazole in enantiomerically pure form;intermediates |
| US8795629B2 (en) * | 2009-02-13 | 2014-08-05 | Brookhaven Science Associates, Llc | Radio-methyl vorozole and methods for making and using the same |
| US8207352B2 (en) * | 2009-10-08 | 2012-06-26 | Drug Process Licensing Associates LLC | Process for the manufacture of enantiomerically pure antifungal azoles as ravuconazole and isavuconazole |
| TWI794385B (zh) | 2018-01-03 | 2023-03-01 | 美商藝康美國公司 | 作為腐蝕抑制劑之苯并三唑衍生物 |
| CN115650962B (zh) * | 2022-10-31 | 2024-07-30 | 吉林大学 | 一种用于钯催化偶联反应的荧光配体化合物及制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ224714A (en) * | 1987-06-01 | 1990-03-27 | Janssen Pharmaceutica Nv | Substituted benzotriazole derivatives and pharmaceutical compositions |
| US4943574A (en) * | 1987-06-01 | 1990-07-24 | Janssen Pharmaceutica N.V. | (1H-azol-1-ylmethyl) substituted benzotriazole derivatives and pharmaceutical compositions containing them |
| CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
| NZ257551A (en) * | 1992-11-10 | 1995-10-26 | Janssen Pharmaceutica Nv | Preparation of 6-[(4-chlorophenyl)(1h-1,2,4-triazol-1-yl)methyl]-1-methyl-1h-benzotriazole in enantiomerically pure form;intermediates |
-
1993
- 1993-11-02 NZ NZ257551A patent/NZ257551A/en unknown
- 1993-11-02 CZ CZ951151A patent/CZ115195A3/cs unknown
- 1993-11-02 RU RU95112576/04A patent/RU95112576A/ru unknown
- 1993-11-02 HU HU9501361A patent/HUT72073A/hu unknown
- 1993-11-02 CA CA002148489A patent/CA2148489A1/en not_active Abandoned
- 1993-11-02 AU AU54203/94A patent/AU679704B2/en not_active Ceased
- 1993-11-02 JP JP6511672A patent/JPH08502990A/ja active Pending
- 1993-11-02 WO PCT/EP1993/003066 patent/WO1994011364A1/en not_active Application Discontinuation
- 1993-11-02 US US08/424,295 patent/US5663354A/en not_active Expired - Lifetime
- 1993-11-02 EP EP93924577A patent/EP0668861A1/en not_active Withdrawn
- 1993-11-02 BR BR9307409A patent/BR9307409A/pt not_active Application Discontinuation
- 1993-11-02 PL PL93308905A patent/PL176059B1/pl unknown
- 1993-11-02 SK SK599-95A patent/SK59995A3/sk unknown
- 1993-11-02 RO RO95-00876A patent/RO114327B1/ro unknown
- 1993-11-02 SG SG1996002244A patent/SG50476A1/en unknown
-
1995
- 1995-04-20 BG BG99594A patent/BG99594A/bg unknown
- 1995-05-09 FI FI952251A patent/FI952251A/fi unknown
- 1995-05-09 NO NO951808A patent/NO951808L/no unknown
-
1997
- 1997-03-28 US US08/827,204 patent/US5746840A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2148489A1 (en) | 1994-05-26 |
| BR9307409A (pt) | 1999-08-24 |
| HUT72073A (en) | 1996-03-28 |
| WO1994011364A1 (en) | 1994-05-26 |
| CZ115195A3 (en) | 1995-11-15 |
| JPH08502990A (ja) | 1996-04-02 |
| PL176059B1 (pl) | 1999-03-31 |
| US5663354A (en) | 1997-09-02 |
| NO951808D0 (no) | 1995-05-09 |
| RO114327B1 (ro) | 1999-03-30 |
| AU679704B2 (en) | 1997-07-10 |
| SK59995A3 (en) | 1995-10-11 |
| SG50476A1 (en) | 1998-07-20 |
| FI952251A0 (fi) | 1995-05-09 |
| AU5420394A (en) | 1994-06-08 |
| RU95112576A (ru) | 1997-03-20 |
| EP0668861A1 (en) | 1995-08-30 |
| NO951808L (no) | 1995-05-09 |
| FI952251A (fi) | 1995-05-09 |
| NZ257551A (en) | 1995-10-26 |
| US5746840A (en) | 1998-05-05 |
| PL308905A1 (en) | 1995-09-04 |
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