BG64540B1 - Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия - Google Patents
Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия Download PDFInfo
- Publication number
- BG64540B1 BG64540B1 BG104797A BG10479700A BG64540B1 BG 64540 B1 BG64540 B1 BG 64540B1 BG 104797 A BG104797 A BG 104797A BG 10479700 A BG10479700 A BG 10479700A BG 64540 B1 BG64540 B1 BG 64540B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- dexmedetomidine
- patient
- patients
- dose
- sedation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8028798P | 1998-04-01 | 1998-04-01 | |
US11094498P | 1998-12-04 | 1998-12-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
BG104797A BG104797A (en) | 2001-07-31 |
BG64540B1 true BG64540B1 (bg) | 2005-07-29 |
Family
ID=26763325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104797A BG64540B1 (bg) | 1998-04-01 | 2000-09-26 | Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP1069893B1 (ja) |
JP (1) | JP4606581B2 (ja) |
KR (1) | KR20010034728A (ja) |
CN (1) | CN1168441C (ja) |
AR (1) | AR015744A1 (ja) |
AT (1) | ATE347359T1 (ja) |
AU (1) | AU754484B2 (ja) |
BG (1) | BG64540B1 (ja) |
BR (1) | BR9909872A (ja) |
CA (1) | CA2326339C (ja) |
CZ (1) | CZ301013B6 (ja) |
DE (1) | DE69934305T2 (ja) |
DK (1) | DK1069893T3 (ja) |
EA (1) | EA005524B1 (ja) |
ES (1) | ES2278441T3 (ja) |
GB (1) | GB2352972B (ja) |
HU (1) | HU229162B1 (ja) |
IL (1) | IL138416A (ja) |
NO (1) | NO329194B1 (ja) |
NZ (1) | NZ507203A (ja) |
PL (1) | PL192517B1 (ja) |
PT (1) | PT1069893E (ja) |
SI (1) | SI1069893T1 (ja) |
SK (1) | SK286160B6 (ja) |
TR (1) | TR200002837T2 (ja) |
TW (1) | TW552136B (ja) |
WO (1) | WO1999049854A2 (ja) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001030347A1 (en) | 1999-10-29 | 2001-05-03 | Orion Corporation | Treatment or prevention of hypotension and shock |
RU2297216C2 (ru) * | 2002-04-08 | 2007-04-20 | Эм-Джи-Ай Джи-Пи,Инк. | Фармацевтические композиции, содержащие растворимые в воде пролекарства пропофола, и способы их применения |
US7141597B2 (en) * | 2003-09-12 | 2006-11-28 | Allergan, Inc. | Nonsedating α-2 agonists |
US20060058700A1 (en) * | 2004-08-26 | 2006-03-16 | Marro Dominic P | Patient sedation monitor |
JP2010504359A (ja) | 2006-09-20 | 2010-02-12 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 局部麻酔および/または疼痛緩和のための、揮発性麻酔剤を送達するための方法 |
DK2244737T3 (da) | 2008-01-22 | 2019-07-08 | Univ Texas | Flygtige anæstetiske sammensætninger omfattende ekstraktionsopløsningsmidler til regional anæstesi og/eller smertelindring |
KR101859486B1 (ko) * | 2009-05-15 | 2018-06-28 | 레크로파마, 인코포레이티드 | 설하용 덱스메데토미딘 조성물과 그의 사용 방법 |
DE102009050016A1 (de) | 2009-05-27 | 2011-05-05 | Modine Manufacturing Co., Racine | Wärmeübertragereinheit |
US20130096170A1 (en) * | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
AU2012352528B9 (en) | 2011-12-11 | 2017-11-02 | Baudax Bio, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
US8242158B1 (en) * | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
JP5921928B2 (ja) * | 2012-03-28 | 2016-05-24 | テルモ株式会社 | 既希釈デクスメデトミジン製剤 |
NZ706990A (en) * | 2012-10-15 | 2017-12-22 | Orion Corp | A veterinary method of alleviating noise aversion |
CN105473669A (zh) | 2013-07-24 | 2016-04-06 | I-技术有限公司 | 作为抑制剂的对映异构体左旋美托咪啶在海洋生物污损表面附着的应用 |
US10772871B2 (en) | 2013-10-07 | 2020-09-15 | Teikoku Pharma Usa, Inc. | Dexmedetomidine transdermal delivery devices and methods for using the same |
TWI709417B (zh) * | 2013-10-07 | 2020-11-11 | 美商帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
EP3054930B1 (en) | 2013-10-07 | 2020-12-02 | Teikoku Pharma USA, Inc. | Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine |
CN113975273B (zh) * | 2020-07-27 | 2023-07-11 | 宜昌人福药业有限责任公司 | 一种抗焦虑用纳米混悬鼻腔喷雾剂及其制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4544664A (en) * | 1981-07-10 | 1985-10-01 | Farmos Group, Ltd. | Antihypertensive substituted imidazole derivatives |
US4670455A (en) * | 1984-12-04 | 1987-06-02 | Farmos-Yhtyma Oy | Method of bringing about sedation and/or analgesia in a mammal |
US4910214A (en) * | 1987-07-16 | 1990-03-20 | Farmos Yhtyma Oy | Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist |
US5344840A (en) * | 1988-02-29 | 1994-09-06 | Orion-Yhtyma Oy | 4-substituted imidazole derivatives useful in perioperative care |
US5712301A (en) * | 1993-08-25 | 1998-01-27 | Orion-yhtyma Oy | Use of dexmedetomidine for treating ethanol-induced neurodegeneration |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2215206B (en) * | 1988-02-29 | 1991-07-03 | Farmos Oy | 4-substituted imidazole derivatives useful in perioperative care |
US5217718A (en) * | 1989-08-18 | 1993-06-08 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
US5124157A (en) * | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
FI894911A0 (fi) * | 1989-10-17 | 1989-10-17 | Farmos Oy | En terapeutiskt vaerdefull foerening. |
-
1999
- 1999-03-30 AR ARP990101414A patent/AR015744A1/es unknown
- 1999-03-31 JP JP2000540820A patent/JP4606581B2/ja not_active Expired - Lifetime
- 1999-03-31 CZ CZ20003484A patent/CZ301013B6/cs not_active IP Right Cessation
- 1999-03-31 HU HU0101498A patent/HU229162B1/hu unknown
- 1999-03-31 AT AT99913332T patent/ATE347359T1/de active
- 1999-03-31 WO PCT/FI1999/000266 patent/WO1999049854A2/en active IP Right Grant
- 1999-03-31 CN CNB998046272A patent/CN1168441C/zh not_active Ceased
- 1999-03-31 NZ NZ507203A patent/NZ507203A/xx not_active IP Right Cessation
- 1999-03-31 CA CA002326339A patent/CA2326339C/en not_active Expired - Lifetime
- 1999-03-31 KR KR1020007010991A patent/KR20010034728A/ko not_active Application Discontinuation
- 1999-03-31 SK SK1436-2000A patent/SK286160B6/sk not_active IP Right Cessation
- 1999-03-31 DK DK99913332T patent/DK1069893T3/da active
- 1999-03-31 EP EP99913332A patent/EP1069893B1/en not_active Expired - Lifetime
- 1999-03-31 DE DE69934305T patent/DE69934305T2/de not_active Expired - Lifetime
- 1999-03-31 ES ES99913332T patent/ES2278441T3/es not_active Expired - Lifetime
- 1999-03-31 GB GB0024932A patent/GB2352972B/en not_active Expired - Lifetime
- 1999-03-31 AU AU31494/99A patent/AU754484B2/en not_active Expired
- 1999-03-31 IL IL13841699A patent/IL138416A/xx not_active IP Right Cessation
- 1999-03-31 TR TR2000/02837T patent/TR200002837T2/xx unknown
- 1999-03-31 PL PL343553A patent/PL192517B1/pl unknown
- 1999-03-31 SI SI9930941T patent/SI1069893T1/sl unknown
- 1999-03-31 EA EA200001010A patent/EA005524B1/ru not_active IP Right Cessation
- 1999-03-31 PT PT99913332T patent/PT1069893E/pt unknown
- 1999-03-31 BR BRPI9909872-5A patent/BR9909872A/pt not_active Application Discontinuation
- 1999-04-01 TW TW088105188A patent/TW552136B/zh not_active IP Right Cessation
-
2000
- 2000-09-26 BG BG104797A patent/BG64540B1/bg unknown
- 2000-09-29 NO NO20004931A patent/NO329194B1/no not_active IP Right Cessation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4544664A (en) * | 1981-07-10 | 1985-10-01 | Farmos Group, Ltd. | Antihypertensive substituted imidazole derivatives |
US4670455A (en) * | 1984-12-04 | 1987-06-02 | Farmos-Yhtyma Oy | Method of bringing about sedation and/or analgesia in a mammal |
US4910214A (en) * | 1987-07-16 | 1990-03-20 | Farmos Yhtyma Oy | Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist |
US5344840A (en) * | 1988-02-29 | 1994-09-06 | Orion-Yhtyma Oy | 4-substituted imidazole derivatives useful in perioperative care |
US5712301A (en) * | 1993-08-25 | 1998-01-27 | Orion-yhtyma Oy | Use of dexmedetomidine for treating ethanol-induced neurodegeneration |
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