BG64540B1 - Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия - Google Patents

Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия Download PDF

Info

Publication number
BG64540B1
BG64540B1 BG104797A BG10479700A BG64540B1 BG 64540 B1 BG64540 B1 BG 64540B1 BG 104797 A BG104797 A BG 104797A BG 10479700 A BG10479700 A BG 10479700A BG 64540 B1 BG64540 B1 BG 64540B1
Authority
BG
Bulgaria
Prior art keywords
dexmedetomidine
patient
patients
dose
sedation
Prior art date
Application number
BG104797A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104797A (en
Inventor
Riku Aantaa
Romeo Bachand
Esa Heinonen
Original Assignee
Orion Corporation
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26763325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG64540(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Corporation, Abbott Laboratories filed Critical Orion Corporation
Publication of BG104797A publication Critical patent/BG104797A/xx
Publication of BG64540B1 publication Critical patent/BG64540B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG104797A 1998-04-01 2000-09-26 Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия BG64540B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8028798P 1998-04-01 1998-04-01
US11094498P 1998-12-04 1998-12-04

Publications (2)

Publication Number Publication Date
BG104797A BG104797A (en) 2001-07-31
BG64540B1 true BG64540B1 (bg) 2005-07-29

Family

ID=26763325

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104797A BG64540B1 (bg) 1998-04-01 2000-09-26 Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия

Country Status (27)

Country Link
EP (1) EP1069893B1 (fr)
JP (1) JP4606581B2 (fr)
KR (1) KR20010034728A (fr)
CN (1) CN1168441C (fr)
AR (1) AR015744A1 (fr)
AT (1) ATE347359T1 (fr)
AU (1) AU754484B2 (fr)
BG (1) BG64540B1 (fr)
BR (1) BR9909872A (fr)
CA (1) CA2326339C (fr)
CZ (1) CZ301013B6 (fr)
DE (1) DE69934305T2 (fr)
DK (1) DK1069893T3 (fr)
EA (1) EA005524B1 (fr)
ES (1) ES2278441T3 (fr)
GB (1) GB2352972B (fr)
HU (1) HU229162B1 (fr)
IL (1) IL138416A (fr)
NO (1) NO329194B1 (fr)
NZ (1) NZ507203A (fr)
PL (1) PL192517B1 (fr)
PT (1) PT1069893E (fr)
SI (1) SI1069893T1 (fr)
SK (1) SK286160B6 (fr)
TR (1) TR200002837T2 (fr)
TW (1) TW552136B (fr)
WO (1) WO1999049854A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030347A1 (fr) 1999-10-29 2001-05-03 Orion Corporation Traitement ou prevention de l'hypotension et de l'etat de choc
KR20070087004A (ko) * 2002-04-08 2007-08-27 엠쥐아이 쥐피, 아이엔씨. 프로포폴의 수용성 프로드럭을 함유하는 약제학적 조성물및 그것을 투여하는 방법
US7141597B2 (en) * 2003-09-12 2006-11-28 Allergan, Inc. Nonsedating α-2 agonists
US20060058700A1 (en) * 2004-08-26 2006-03-16 Marro Dominic P Patient sedation monitor
WO2008036858A2 (fr) 2006-09-20 2008-03-27 The Board Of Regents Of The University Of Texas System procédé pour administrer des anesthésiants volatils pour une anesthésie locale et/ou le soulagement de la douleur
WO2009094459A1 (fr) 2008-01-22 2009-07-30 The Board Of Regents Of The University Of Texas System Compositions anesthésiques volatiles comprenant des solvants d'extraction pour une anesthésie régionale et/ou un soulagement de la douleur
KR101859486B1 (ko) * 2009-05-15 2018-06-28 레크로파마, 인코포레이티드 설하용 덱스메데토미딘 조성물과 그의 사용 방법
DE102009050016A1 (de) 2009-05-27 2011-05-05 Modine Manufacturing Co., Racine Wärmeübertragereinheit
US20130096170A1 (en) * 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
EP2787970B1 (fr) 2011-12-11 2018-04-11 Recro Pharma, Inc. Compositions intranasales de dexmédétomidine et leurs procédés d'utilisation
US8242158B1 (en) * 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
JP5921928B2 (ja) * 2012-03-28 2016-05-24 テルモ株式会社 既希釈デクスメデトミジン製剤
US10780079B2 (en) * 2012-10-15 2020-09-22 Orion Corporation Veterinary method of alleviating noise aversion
WO2015011177A1 (fr) 2013-07-24 2015-01-29 I-Tech Ab Utilisation de la lévomédétomidine énantiomère comme inhibitrice des bio-salissures marines des surfaces
RU2648449C2 (ru) * 2013-10-07 2018-03-26 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина
EP3054935B1 (fr) * 2013-10-07 2020-12-09 Teikoku Pharma USA, Inc. Méthodes et compositions permettant de traiter le trouble d'hyperactivité avec déficit de l'attention, l'anxiété et l'insomnie à l'aide de compositions transdermiques de dexmédétomidine
KR101827980B1 (ko) * 2013-10-07 2018-02-13 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
CN113975273B (zh) * 2020-07-27 2023-07-11 宜昌人福药业有限责任公司 一种抗焦虑用纳米混悬鼻腔喷雾剂及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4544664A (en) * 1981-07-10 1985-10-01 Farmos Group, Ltd. Antihypertensive substituted imidazole derivatives
US4670455A (en) * 1984-12-04 1987-06-02 Farmos-Yhtyma Oy Method of bringing about sedation and/or analgesia in a mammal
US4910214A (en) * 1987-07-16 1990-03-20 Farmos Yhtyma Oy Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist
US5344840A (en) * 1988-02-29 1994-09-06 Orion-Yhtyma Oy 4-substituted imidazole derivatives useful in perioperative care
US5712301A (en) * 1993-08-25 1998-01-27 Orion-yhtyma Oy Use of dexmedetomidine for treating ethanol-induced neurodegeneration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4544664A (en) * 1981-07-10 1985-10-01 Farmos Group, Ltd. Antihypertensive substituted imidazole derivatives
US4670455A (en) * 1984-12-04 1987-06-02 Farmos-Yhtyma Oy Method of bringing about sedation and/or analgesia in a mammal
US4910214A (en) * 1987-07-16 1990-03-20 Farmos Yhtyma Oy Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist
US5344840A (en) * 1988-02-29 1994-09-06 Orion-Yhtyma Oy 4-substituted imidazole derivatives useful in perioperative care
US5712301A (en) * 1993-08-25 1998-01-27 Orion-yhtyma Oy Use of dexmedetomidine for treating ethanol-induced neurodegeneration

Also Published As

Publication number Publication date
IL138416A (en) 2005-07-25
CA2326339A1 (fr) 1999-10-07
TR200002837T2 (tr) 2001-01-22
CN1295473A (zh) 2001-05-16
DK1069893T3 (da) 2007-03-19
WO1999049854A3 (fr) 1999-11-18
SI1069893T1 (sl) 2007-04-30
CA2326339C (fr) 2008-12-23
DE69934305T2 (de) 2007-07-12
WO1999049854A2 (fr) 1999-10-07
SK286160B6 (sk) 2008-04-07
NO20004931L (no) 2000-09-29
EP1069893A2 (fr) 2001-01-24
CZ301013B6 (cs) 2009-10-14
GB2352972A (en) 2001-02-14
NZ507203A (en) 2003-03-28
EA200001010A1 (ru) 2001-02-26
AU754484B2 (en) 2002-11-14
ATE347359T1 (de) 2006-12-15
AU3149499A (en) 1999-10-18
JP2002509880A (ja) 2002-04-02
EA005524B1 (ru) 2005-04-28
NO329194B1 (no) 2010-09-13
EP1069893B1 (fr) 2006-12-06
KR20010034728A (ko) 2001-04-25
HU229162B1 (hu) 2013-09-30
GB2352972B (en) 2003-05-21
HUP0101498A1 (hu) 2002-03-28
ES2278441T3 (es) 2007-08-01
PT1069893E (pt) 2007-01-31
AR015744A1 (es) 2001-05-16
PL192517B1 (pl) 2006-10-31
BG104797A (en) 2001-07-31
JP4606581B2 (ja) 2011-01-05
DE69934305D1 (de) 2007-01-18
PL343553A1 (en) 2001-08-27
TW552136B (en) 2003-09-11
NO20004931D0 (no) 2000-09-29
SK14362000A3 (sk) 2002-03-05
CZ20003484A3 (cs) 2002-01-16
HUP0101498A3 (en) 2002-06-28
BR9909872A (pt) 2007-11-20
GB0024932D0 (en) 2000-11-29
IL138416A0 (en) 2001-10-31
CN1168441C (zh) 2004-09-29

Similar Documents

Publication Publication Date Title
BG64540B1 (bg) Използване на дексмедетомидин за постигане на седативен ефект в отделение за интензивна терапия
Hofer et al. Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics
Pain Pain management
US6716867B1 (en) Use of dexmedetomidine for ICU sedation
Cromhout Ketamine: its use in the emergency department
JP2013541583A (ja) 組み合わせ組成物
Hellyer Pain management
Imbelloni et al. Low dose of isobaric bupivacaine provides lower incidence of spinal hypotension for hip surgery in elderly patients
Ali et al. Dexmedetomidine versus ketofol effect on the incidence of emergence agitation associated with sevoflurane-based anesthesia in children undergoing orthopedic surgery
US20130123298A1 (en) Pharmaceutical composition for the prevention of perioperative arterial hypotension in humans
Walder et al. Propofol and midazolam versus propofol alone for sedation following coronary artery bypass grafting: a randomized, placebo-controlled trial
Flaherty Anaesthetic drugs
Esmat et al. Comparative study between transdermal fentanyl and melatonin patches on postoperative pain relief after lumber laminectomy, a double-blind, placebo-controlled trial
RU2664693C1 (ru) Способ предоперационной подготовки пациентов к офтальмологическим операциям
RU2557882C1 (ru) Способ проведения премедикации при плановом хирургическом лечении
Mamatha Comparative Study Between Dexmedetomidine and Midazolam in Inducing Conscious Sedation in Patient Undergoing Cataract Surgery
Ramya A Comparative Study Of Dexmedetomidine Versus Midazolam For Monitored Anaesthesia Care In Middle Ear Surgeries
Marechal et al. Choice of sedation in neurointensive care
Jurakulovich et al. The Role of Carrying Out Combined Unilateral Spinal and Epidural Anesthesia Using Low Doses of Local Anesthetics in Elderly Patients in Lower Limb Joint Arthroplasty
WO2023201390A1 (fr) Solutions aqueuses de quétiapine
FRH Comparison of Intrathecal Dexmedetomidine and Buprenorphine as Adjuvant to Bupivacaine for Lower Limb Surgeries
Raghuram A Comparative Study of Efficacy of Dexmedetomidine and Propofol for Conscious Sedation in Remote Location
Hiremath A Clinical Comparative Study of Propofol and Ketamine Combination (Ketofol) Versus Either Drug Alone in Short Surgeries and Procedures
WO2005074928A1 (fr) Remede pour l'hypertension
Joffe et al. Transient anesthetic-induced worsening of existing left-sided weakness in a patient undergoing elective anterior cervical discectomy