BG64530B1 - Метод за синтез на пироламиди - Google Patents

Метод за синтез на пироламиди Download PDF

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Publication number
BG64530B1
BG64530B1 BG104413A BG10441300A BG64530B1 BG 64530 B1 BG64530 B1 BG 64530B1 BG 104413 A BG104413 A BG 104413A BG 10441300 A BG10441300 A BG 10441300A BG 64530 B1 BG64530 B1 BG 64530B1
Authority
BG
Bulgaria
Prior art keywords
oxo
tetrahydro
methyl
carboxylic acid
phenyl
Prior art date
Application number
BG104413A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104413A (en
Inventor
John RAGAN
Teresa MAKOWSKI
Ende David Am
Pamela Clifford
Gregory Young
Alyson Conrad
Shane EISENBEIS
Douglas Allen
George Quallich
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG104413A publication Critical patent/BG104413A/xx
Publication of BG64530B1 publication Critical patent/BG64530B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Tea And Coffee (AREA)
  • Fats And Perfumes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
BG104413A 1997-11-13 2000-05-09 Метод за синтез на пироламиди BG64530B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6542297P 1997-11-13 1997-11-13
US7426698P 1998-02-10 1998-02-10

Publications (2)

Publication Number Publication Date
BG104413A BG104413A (en) 2001-02-28
BG64530B1 true BG64530B1 (bg) 2005-06-30

Family

ID=26745584

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104413A BG64530B1 (bg) 1997-11-13 2000-05-09 Метод за синтез на пироламиди

Country Status (35)

Country Link
US (1) US6262272B1 (fr)
EP (1) EP1030838B1 (fr)
JP (1) JP3497469B2 (fr)
KR (1) KR100386722B1 (fr)
CN (2) CN1280566A (fr)
AT (1) ATE231492T1 (fr)
AU (1) AU745788B2 (fr)
BG (1) BG64530B1 (fr)
BR (1) BR9814161A (fr)
CA (1) CA2310095A1 (fr)
CZ (1) CZ20001769A3 (fr)
DE (1) DE69810959T2 (fr)
DK (1) DK1030838T3 (fr)
DZ (1) DZ2651A1 (fr)
EA (1) EA002243B1 (fr)
ES (1) ES2186232T3 (fr)
HR (1) HRP20000298A2 (fr)
HU (1) HUP0100235A3 (fr)
ID (1) ID24135A (fr)
IL (1) IL135710A0 (fr)
IS (1) IS5469A (fr)
MA (1) MA24697A1 (fr)
NO (1) NO20002214L (fr)
NZ (1) NZ503916A (fr)
OA (1) OA11378A (fr)
PA (1) PA8462901A1 (fr)
PL (1) PL340554A1 (fr)
PT (1) PT1030838E (fr)
SK (1) SK6872000A3 (fr)
TN (1) TNSN98204A1 (fr)
TR (1) TR200001343T2 (fr)
TW (1) TW509675B (fr)
UY (1) UY25249A1 (fr)
WO (1) WO1999025684A1 (fr)
YU (1) YU27300A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200200111A (et) * 1999-08-31 2003-06-16 Neurogen Corporation Kondenseerunud pürroolkarboksamiidid: aju GABA-retseptori ligandid
MXPA03001945A (es) * 2000-09-06 2003-09-10 Neurogen Corp Tetrahidroindazoles sustituidos con arilo y su uso como ligandos para el receptor gaba-a.
JP2004515491A (ja) * 2000-12-04 2004-05-27 ファイザー・プロダクツ・インク 縮合ピロールカルボキサミド類の合成
US6852730B2 (en) 2002-02-07 2005-02-08 Neurogen Corporation Substituted fused pyrazolecarboxylic acid arylamides and related compounds
US20080153629A1 (en) * 2004-05-07 2008-06-26 Sullivan Michael J Thick Outer Cover Layer Golf Ball
CN102786458B (zh) * 2012-06-04 2014-02-12 天津渤海职业技术学院 吡咯甲酰胺衍生物、其制备方法和用途
SG11201605915WA (en) * 2014-01-24 2016-08-30 Abbvie Inc Furo-3-carboxamide derivatives and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750702A (en) 1993-10-27 1998-05-12 Neurogen Corporation Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands
US5484944A (en) * 1993-10-27 1996-01-16 Neurogen Corporation Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands
US5804686A (en) * 1996-01-19 1998-09-08 Neurogen Corporation fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
WO1997034870A1 (fr) 1996-03-22 1997-09-25 Neurogen Corporation Certains pyrrolecarboxamides fusionnes utilises comme ligands de recepteurs cerebraux gaba

Also Published As

Publication number Publication date
KR20010032063A (ko) 2001-04-16
DE69810959T2 (de) 2003-06-05
ATE231492T1 (de) 2003-02-15
BG104413A (en) 2001-02-28
HUP0100235A2 (hu) 2001-12-28
IL135710A0 (en) 2001-05-20
US6262272B1 (en) 2001-07-17
AU9363998A (en) 1999-06-07
YU27300A (sh) 2002-10-18
EP1030838A1 (fr) 2000-08-30
UY25249A1 (es) 1999-07-19
EA200000413A1 (ru) 2000-12-25
DK1030838T3 (da) 2003-02-24
TW509675B (en) 2002-11-11
CA2310095A1 (fr) 1999-05-27
SK6872000A3 (en) 2002-02-05
HRP20000298A2 (en) 2001-02-28
EA002243B1 (ru) 2002-02-28
AU745788B2 (en) 2002-03-28
HUP0100235A3 (en) 2002-04-29
JP2001523660A (ja) 2001-11-27
ES2186232T3 (es) 2003-05-01
DZ2651A1 (fr) 2003-03-15
DE69810959D1 (de) 2003-02-27
CN1508129A (zh) 2004-06-30
OA11378A (en) 2004-01-27
PT1030838E (pt) 2003-03-31
JP3497469B2 (ja) 2004-02-16
EP1030838B1 (fr) 2003-01-22
IS5469A (is) 2000-04-26
NO20002214D0 (no) 2000-04-28
NO20002214L (no) 2000-05-12
MA24697A1 (fr) 1999-07-01
WO1999025684A1 (fr) 1999-05-27
NZ503916A (en) 2002-08-28
CZ20001769A3 (cs) 2001-09-12
PL340554A1 (en) 2001-02-12
KR100386722B1 (ko) 2003-06-09
TNSN98204A1 (fr) 2005-03-15
BR9814161A (pt) 2000-09-26
ID24135A (id) 2000-07-06
PA8462901A1 (es) 2000-05-24
CN1280566A (zh) 2001-01-17
TR200001343T2 (tr) 2001-02-21

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