DE69810959D1 - Verfahren zur herstellung von pyrrolamiden - Google Patents
Verfahren zur herstellung von pyrrolamidenInfo
- Publication number
- DE69810959D1 DE69810959D1 DE69810959T DE69810959T DE69810959D1 DE 69810959 D1 DE69810959 D1 DE 69810959D1 DE 69810959 T DE69810959 T DE 69810959T DE 69810959 T DE69810959 T DE 69810959T DE 69810959 D1 DE69810959 D1 DE 69810959D1
- Authority
- DE
- Germany
- Prior art keywords
- pyrrolamides
- producing
- reaction
- followed
- cycloakane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Tea And Coffee (AREA)
- Fats And Perfumes (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6542297P | 1997-11-13 | 1997-11-13 | |
| US7426698P | 1998-02-10 | 1998-02-10 | |
| PCT/IB1998/001672 WO1999025684A1 (en) | 1997-11-13 | 1998-10-21 | Method of synthesis of pyrrole amides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69810959D1 true DE69810959D1 (de) | 2003-02-27 |
| DE69810959T2 DE69810959T2 (de) | 2003-06-05 |
Family
ID=26745584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69810959T Expired - Fee Related DE69810959T2 (de) | 1997-11-13 | 1998-10-21 | Verfahren zur herstellung von pyrrolamiden |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6262272B1 (de) |
| EP (1) | EP1030838B1 (de) |
| JP (1) | JP3497469B2 (de) |
| KR (1) | KR100386722B1 (de) |
| CN (2) | CN1508129A (de) |
| AT (1) | ATE231492T1 (de) |
| AU (1) | AU745788B2 (de) |
| BG (1) | BG64530B1 (de) |
| BR (1) | BR9814161A (de) |
| CA (1) | CA2310095A1 (de) |
| CZ (1) | CZ20001769A3 (de) |
| DE (1) | DE69810959T2 (de) |
| DK (1) | DK1030838T3 (de) |
| DZ (1) | DZ2651A1 (de) |
| EA (1) | EA002243B1 (de) |
| ES (1) | ES2186232T3 (de) |
| HR (1) | HRP20000298A2 (de) |
| HU (1) | HUP0100235A3 (de) |
| ID (1) | ID24135A (de) |
| IL (1) | IL135710A0 (de) |
| IS (1) | IS5469A (de) |
| MA (1) | MA24697A1 (de) |
| NO (1) | NO20002214L (de) |
| NZ (1) | NZ503916A (de) |
| OA (1) | OA11378A (de) |
| PA (1) | PA8462901A1 (de) |
| PL (1) | PL340554A1 (de) |
| PT (1) | PT1030838E (de) |
| SK (1) | SK6872000A3 (de) |
| TN (1) | TNSN98204A1 (de) |
| TR (1) | TR200001343T2 (de) |
| TW (1) | TW509675B (de) |
| UY (1) | UY25249A1 (de) |
| WO (1) | WO1999025684A1 (de) |
| YU (1) | YU27300A (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7092800A (en) | 1999-08-31 | 2001-03-26 | Neurogen Corporation | Fused pyrrolecarboxamides: gaba brain receptor ligands |
| JP2004508359A (ja) | 2000-09-06 | 2004-03-18 | ニューロゲン コーポレイション | アリール置換テトラヒドロインダゾール、及び、ｇａｂａ−ａ受容体に対するリガンドとしてのそれらの使用 |
| BR0115874A (pt) * | 2000-12-04 | 2003-10-28 | Pfizer Prod Inc | Sìntese de pirrole-amidas |
| WO2003066634A1 (en) | 2002-02-07 | 2003-08-14 | Neurogen Corporation | Substituted fused pyrazolecarboxylic acid arylamides and related compounds |
| US20080153629A1 (en) * | 2004-05-07 | 2008-06-26 | Sullivan Michael J | Thick Outer Cover Layer Golf Ball |
| CN102786458B (zh) * | 2012-06-04 | 2014-02-12 | 天津渤海职业技术学院 | 吡咯甲酰胺衍生物、其制备方法和用途 |
| EP3097095A1 (de) * | 2014-01-24 | 2016-11-30 | AbbVie Inc. | Furo-3-carboxamid-derivate und verfahren zur verwendung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750702A (en) | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
| US5484944A (en) | 1993-10-27 | 1996-01-16 | Neurogen Corporation | Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands |
| US5804686A (en) | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
| EP0888300A1 (de) | 1996-03-22 | 1999-01-07 | Neurogen Corporation | Kondensierte pyrrolcarboxamide als gaba-gehirn-rezeptor-liganden |
-
1998
- 1998-10-21 PT PT98946678T patent/PT1030838E/pt unknown
- 1998-10-21 WO PCT/IB1998/001672 patent/WO1999025684A1/en not_active Application Discontinuation
- 1998-10-21 HU HU0100235A patent/HUP0100235A3/hu unknown
- 1998-10-21 IL IL13571098A patent/IL135710A0/xx unknown
- 1998-10-21 US US09/403,985 patent/US6262272B1/en not_active Expired - Fee Related
- 1998-10-21 PL PL98340554A patent/PL340554A1/xx not_active Application Discontinuation
- 1998-10-21 EP EP98946678A patent/EP1030838B1/de not_active Expired - Lifetime
- 1998-10-21 CN CNA031594727A patent/CN1508129A/zh active Pending
- 1998-10-21 CA CA002310095A patent/CA2310095A1/en not_active Abandoned
- 1998-10-21 KR KR10-2000-7005185A patent/KR100386722B1/ko not_active IP Right Cessation
- 1998-10-21 ID IDW20000893A patent/ID24135A/id unknown
- 1998-10-21 CZ CZ20001769A patent/CZ20001769A3/cs unknown
- 1998-10-21 AT AT98946678T patent/ATE231492T1/de not_active IP Right Cessation
- 1998-10-21 JP JP2000521068A patent/JP3497469B2/ja not_active Expired - Fee Related
- 1998-10-21 DK DK98946678T patent/DK1030838T3/da active
- 1998-10-21 NZ NZ503916A patent/NZ503916A/xx unknown
- 1998-10-21 EA EA200000413A patent/EA002243B1/ru not_active IP Right Cessation
- 1998-10-21 BR BR9814161-9A patent/BR9814161A/pt not_active Application Discontinuation
- 1998-10-21 AU AU93639/98A patent/AU745788B2/en not_active Ceased
- 1998-10-21 TR TR2000/01343T patent/TR200001343T2/xx unknown
- 1998-10-21 ES ES98946678T patent/ES2186232T3/es not_active Expired - Lifetime
- 1998-10-21 YU YU27300A patent/YU27300A/sh unknown
- 1998-10-21 CN CN98811119A patent/CN1280566A/zh active Pending
- 1998-10-21 DE DE69810959T patent/DE69810959T2/de not_active Expired - Fee Related
- 1998-10-21 SK SK687-2000A patent/SK6872000A3/sk unknown
- 1998-11-10 PA PA19988462901A patent/PA8462901A1/es unknown
- 1998-11-10 TW TW087118708A patent/TW509675B/zh not_active IP Right Cessation
- 1998-11-11 MA MA25342A patent/MA24697A1/fr unknown
- 1998-11-11 TN TNTNSN98204A patent/TNSN98204A1/fr unknown
- 1998-11-11 DZ DZ980261A patent/DZ2651A1/xx active
- 1998-11-13 UY UY25249A patent/UY25249A1/es not_active IP Right Cessation
-
2000
- 2000-04-26 IS IS5469A patent/IS5469A/is unknown
- 2000-04-28 NO NO20002214A patent/NO20002214L/no unknown
- 2000-05-09 BG BG104413A patent/BG64530B1/bg unknown
- 2000-05-12 HR HR20000298A patent/HRP20000298A2/hr not_active Application Discontinuation
- 2000-05-12 OA OA1200000136A patent/OA11378A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |