ATE219040T1 - Verfahren zur herstellung von sevoflurane - Google Patents
Verfahren zur herstellung von sevofluraneInfo
- Publication number
- ATE219040T1 ATE219040T1 AT98306585T AT98306585T ATE219040T1 AT E219040 T1 ATE219040 T1 AT E219040T1 AT 98306585 T AT98306585 T AT 98306585T AT 98306585 T AT98306585 T AT 98306585T AT E219040 T1 ATE219040 T1 AT E219040T1
- Authority
- AT
- Austria
- Prior art keywords
- producing sevoflurane
- sevoflurane
- producing
- mixture
- 2choch2cl
- Prior art date
Links
- DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical compound FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960002078 sevoflurane Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- HHYFUCXZHKDNPT-UHFFFAOYSA-N 2-(chloromethoxy)-1,1,1,3,3,3-hexafluoropropane Chemical compound FC(F)(F)C(C(F)(F)F)OCCl HHYFUCXZHKDNPT-UHFFFAOYSA-N 0.000 abstract 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Artificial Filaments (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/912,520 US5969193A (en) | 1997-08-18 | 1997-08-18 | Method for the preparation of sevoflurane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE219040T1 true ATE219040T1 (de) | 2002-06-15 |
Family
ID=25432067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98306585T ATE219040T1 (de) | 1997-08-18 | 1998-08-18 | Verfahren zur herstellung von sevoflurane |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US5969193A (de) |
| EP (1) | EP0901999B1 (de) |
| JP (1) | JP4166870B2 (de) |
| AT (1) | ATE219040T1 (de) |
| DE (1) | DE69805926T2 (de) |
| ES (1) | ES2155278T3 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE250801T1 (de) * | 1996-03-08 | 2003-10-15 | Motorola Inc | Verfahren und gerät zum erkennen von geräuschsignalproben aus einem geräusch |
| US5969193A (en) * | 1997-08-18 | 1999-10-19 | Medeva Pharmaceuticals Pa, Inc. | Method for the preparation of sevoflurane |
| US6100434A (en) * | 1999-03-26 | 2000-08-08 | Abbott Laboratories | Method for synthesizing sevoflurane and an intermediate thereof |
| ATE267785T1 (de) | 1999-09-04 | 2004-06-15 | Solvay Fluor & Derivate | Regenerierung von oniumfluorid-hf-addukten |
| US6469219B1 (en) * | 2000-03-16 | 2002-10-22 | Halocarbon Products Corporation | Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
| US6271422B1 (en) * | 2000-06-01 | 2001-08-07 | Abbott Laboratories | Method for fluoromethylation of alcohols via halogenative decarboxylation |
| US6245949B1 (en) * | 2000-06-01 | 2001-06-12 | Abbott Laboratories | Synthetic method for the fluoromethylation of alcohols |
| PL380525A1 (pl) * | 2004-01-05 | 2007-02-19 | Halocarbon Products Corporation | Chromatograficzna metoda analizy zarówno w sposobie wytwarzania sewofluranu, jak też w końcowym sewofluranie |
| CN102631335A (zh) * | 2005-04-18 | 2012-08-15 | 皮拉莫危急护理有限公司 | 含水量可忽略的七氟烷的制备方法 |
| KR100997836B1 (ko) * | 2005-08-04 | 2010-12-01 | 할로카본 프로덕츠 코포레이션 | 플루오로메틸 1,1,1,3,3,3-헥사플루오로이소프로필에테르(세보플루란)의 정제 방법 |
| JP5315609B2 (ja) | 2006-06-05 | 2013-10-16 | ダイキン工業株式会社 | 新規カルボン酸化合物、その用途及びその製造方法 |
| JP5114880B2 (ja) | 2006-07-06 | 2013-01-09 | ダイキン工業株式会社 | 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法 |
| RU2368597C2 (ru) * | 2007-08-06 | 2009-09-27 | Закрытое акционерное общество Научно-производственное объединение "ПиМ-Инвест" | Двухстадийный способ получения 2-(фторметокси)-1,1,1,3,3,3-гексафторизопропана (севофлурана) |
| JP5163064B2 (ja) | 2007-11-13 | 2013-03-13 | ダイキン工業株式会社 | 新規カルボン酸エステル、その用途及びその製造方法 |
| US20090275785A1 (en) * | 2008-05-01 | 2009-11-05 | Barry Jones | Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process |
| CA2769797A1 (en) | 2009-08-10 | 2011-02-17 | Solvay Fluor Gmbh | Process for the manufacture of sevoflurane |
| US9102604B1 (en) | 2010-02-15 | 2015-08-11 | Baxter International Inc. | Methods for cleaning distilling columns |
| WO2012107438A1 (en) | 2011-02-10 | 2012-08-16 | Solvay Sa | Process for the manufacture of fluoromethoxymalonic acid derivatives |
| US8729313B2 (en) * | 2011-08-15 | 2014-05-20 | Baxter International Inc. | Process for the manufacturing of sevoflurane |
| RU2479566C1 (ru) * | 2012-01-11 | 2013-04-20 | Общество с ограниченной ответственностью "Пермская химическая компания" | Способ получения севофлурана |
| CN103804151A (zh) * | 2012-11-07 | 2014-05-21 | 东莞市长安东阳光铝业研发有限公司 | 一种七氟醚的制备方法 |
| CN103173889B (zh) * | 2013-04-16 | 2015-01-14 | 江苏江南高纤股份有限公司 | 仿羊毛涤纶短纤维及其制备方法 |
| RU2656210C1 (ru) * | 2017-10-17 | 2018-06-01 | Федеральное государственное унитарное предприятие "Российский научный центр "Прикладная химия" | Способ получения 2-(фторметокси)-1,1,1,3,3,3-гексафторизопропана (севофлурана) |
| CN113943214B (zh) * | 2021-11-11 | 2023-12-19 | 福建海西联合药业有限公司 | 一种运用于七氟烷生产的工艺 |
| WO2025041740A1 (ja) * | 2023-08-21 | 2025-02-27 | セントラル硝子株式会社 | 組成物、脱水剤及び脱水方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3911024A (en) * | 1966-12-08 | 1975-10-07 | Louise S Croix | Fluorinated isopropyl derivatives |
| US3683092A (en) * | 1970-07-31 | 1972-08-08 | Baxter Laboratories Inc | Method of anesthesia |
| US3897502A (en) * | 1971-10-22 | 1975-07-29 | Airco Inc | Process for making fluorinated ethers |
| DE2823969A1 (de) * | 1978-06-01 | 1979-12-13 | Hoechst Ag | Verfahren zur herstellung organischer fluorverbindungen |
| US4250334A (en) * | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
| US4328376A (en) * | 1980-03-31 | 1982-05-04 | Baxter Travenol Laboratories, Inc. | Method of removing fluorinated olefin byproduct formed during the synthesis of a fluorinated ether |
| US4874901A (en) * | 1988-05-06 | 1989-10-17 | Boc, Inc. | Process for the production of polyfluorinated ethers |
| US4874902A (en) * | 1988-05-20 | 1989-10-17 | Boc, Inc. | Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether |
| US4996371A (en) * | 1990-01-16 | 1991-02-26 | Boc, Inc. | Method for fluorodecarboxylation |
| GB9023370D0 (en) * | 1990-10-26 | 1990-12-05 | Rhone Poulenc Chemicals | Synthesis of fluorinated substituted ethanes |
| US5969193A (en) * | 1997-08-18 | 1999-10-19 | Medeva Pharmaceuticals Pa, Inc. | Method for the preparation of sevoflurane |
| US5886239A (en) * | 1997-11-21 | 1999-03-23 | Baxter International Inc. | Method of preparing monofluoromethyl ethers |
-
1997
- 1997-08-18 US US08/912,520 patent/US5969193A/en not_active Expired - Lifetime
-
1998
- 1998-08-18 AT AT98306585T patent/ATE219040T1/de not_active IP Right Cessation
- 1998-08-18 EP EP98306585A patent/EP0901999B1/de not_active Revoked
- 1998-08-18 DE DE69805926T patent/DE69805926T2/de not_active Revoked
- 1998-08-18 JP JP23131898A patent/JP4166870B2/ja not_active Expired - Fee Related
- 1998-08-26 ES ES98306858T patent/ES2155278T3/es not_active Expired - Lifetime
-
1999
- 1999-06-21 US US09/337,019 patent/US20010056213A1/en not_active Abandoned
-
2002
- 2002-07-11 US US10/193,786 patent/US20020177739A1/en not_active Abandoned
-
2003
- 2003-08-20 US US10/644,500 patent/US7202386B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7202386B2 (en) | 2007-04-10 |
| US20010056213A1 (en) | 2001-12-27 |
| US20040087817A1 (en) | 2004-05-06 |
| JP4166870B2 (ja) | 2008-10-15 |
| EP0901999A1 (de) | 1999-03-17 |
| US5969193A (en) | 1999-10-19 |
| ES2155278T3 (es) | 2001-05-01 |
| US20020177739A1 (en) | 2002-11-28 |
| DE69805926T2 (de) | 2002-09-26 |
| JPH11116521A (ja) | 1999-04-27 |
| EP0901999B1 (de) | 2002-06-12 |
| DE69805926D1 (de) | 2002-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |