DE69805926D1 - Verfahren zur Herstellung von Sevoflurane - Google Patents
Verfahren zur Herstellung von SevofluraneInfo
- Publication number
- DE69805926D1 DE69805926D1 DE69805926T DE69805926T DE69805926D1 DE 69805926 D1 DE69805926 D1 DE 69805926D1 DE 69805926 T DE69805926 T DE 69805926T DE 69805926 T DE69805926 T DE 69805926T DE 69805926 D1 DE69805926 D1 DE 69805926D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- sevoflurane
- mixture
- 2choch2cl
- 2choch2f
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/912,520 US5969193A (en) | 1997-08-18 | 1997-08-18 | Method for the preparation of sevoflurane |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69805926D1 true DE69805926D1 (de) | 2002-07-18 |
DE69805926T2 DE69805926T2 (de) | 2002-09-26 |
Family
ID=25432067
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69805926T Revoked DE69805926T2 (de) | 1997-08-18 | 1998-08-18 | Verfahren zur Herstellung von Sevoflurane |
Country Status (6)
Country | Link |
---|---|
US (4) | US5969193A (de) |
EP (1) | EP0901999B1 (de) |
JP (1) | JP4166870B2 (de) |
AT (1) | ATE219040T1 (de) |
DE (1) | DE69805926T2 (de) |
ES (1) | ES2155278T3 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69725172T2 (de) * | 1996-03-08 | 2004-04-08 | Motorola, Inc., Schaumburg | Verfahren und gerät zum erkennen von geräuschsignalproben aus einem geräusch |
US5969193A (en) * | 1997-08-18 | 1999-10-19 | Medeva Pharmaceuticals Pa, Inc. | Method for the preparation of sevoflurane |
US6100434A (en) * | 1999-03-26 | 2000-08-08 | Abbott Laboratories | Method for synthesizing sevoflurane and an intermediate thereof |
WO2001017931A2 (de) | 1999-09-04 | 2001-03-15 | Solvay Fluor Und Derivate Gmbh | Regenerierung von oniumfluorid-hf-addukten |
US6469219B1 (en) | 2000-03-16 | 2002-10-22 | Halocarbon Products Corporation | Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether |
US6245949B1 (en) * | 2000-06-01 | 2001-06-12 | Abbott Laboratories | Synthetic method for the fluoromethylation of alcohols |
US6271422B1 (en) * | 2000-06-01 | 2001-08-07 | Abbott Laboratories | Method for fluoromethylation of alcohols via halogenative decarboxylation |
CZ2006444A3 (cs) * | 2004-01-05 | 2007-02-07 | Halocarbon Products Corporation | Chromatografický postup analýzy sevofluranu behemprípravy a konecného sevofluranu |
EP1871734A4 (de) * | 2005-04-18 | 2010-08-04 | Piramal Critical Care Inc | Herstellung von sevofluran mit geringfügigem wassergehalt |
WO2007019161A2 (en) | 2005-08-04 | 2007-02-15 | Halocarbon Products Corporation | Purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane) |
JP5315609B2 (ja) * | 2006-06-05 | 2013-10-16 | ダイキン工業株式会社 | 新規カルボン酸化合物、その用途及びその製造方法 |
JP5114880B2 (ja) * | 2006-07-06 | 2013-01-09 | ダイキン工業株式会社 | 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法 |
JP5163064B2 (ja) * | 2007-11-13 | 2013-03-13 | ダイキン工業株式会社 | 新規カルボン酸エステル、その用途及びその製造方法 |
US20090275785A1 (en) * | 2008-05-01 | 2009-11-05 | Barry Jones | Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process |
CN102498085A (zh) | 2009-08-10 | 2012-06-13 | 苏威氟有限公司 | 用于制造七氟烷的方法 |
US9102604B1 (en) | 2010-02-15 | 2015-08-11 | Baxter International Inc. | Methods for cleaning distilling columns |
EP2673256B1 (de) | 2011-02-10 | 2015-04-08 | Solvay SA | Verfahren zur herstellung von fluormethoxymalonsäurederivaten |
US8729313B2 (en) * | 2011-08-15 | 2014-05-20 | Baxter International Inc. | Process for the manufacturing of sevoflurane |
RU2479566C1 (ru) * | 2012-01-11 | 2013-04-20 | Общество с ограниченной ответственностью "Пермская химическая компания" | Способ получения севофлурана |
CN103804151A (zh) * | 2012-11-07 | 2014-05-21 | 东莞市长安东阳光铝业研发有限公司 | 一种七氟醚的制备方法 |
CN103173889B (zh) * | 2013-04-16 | 2015-01-14 | 江苏江南高纤股份有限公司 | 仿羊毛涤纶短纤维及其制备方法 |
RU2656210C1 (ru) * | 2017-10-17 | 2018-06-01 | Федеральное государственное унитарное предприятие "Российский научный центр "Прикладная химия" | Способ получения 2-(фторметокси)-1,1,1,3,3,3-гексафторизопропана (севофлурана) |
CN113943214B (zh) * | 2021-11-11 | 2023-12-19 | 福建海西联合药业有限公司 | 一种运用于七氟烷生产的工艺 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3911024A (en) * | 1966-12-08 | 1975-10-07 | Louise S Croix | Fluorinated isopropyl derivatives |
US3683092A (en) * | 1970-07-31 | 1972-08-08 | Baxter Laboratories Inc | Method of anesthesia |
US3897502A (en) * | 1971-10-22 | 1975-07-29 | Airco Inc | Process for making fluorinated ethers |
DE2823969A1 (de) * | 1978-06-01 | 1979-12-13 | Hoechst Ag | Verfahren zur herstellung organischer fluorverbindungen |
US4250334A (en) * | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
US4328376A (en) * | 1980-03-31 | 1982-05-04 | Baxter Travenol Laboratories, Inc. | Method of removing fluorinated olefin byproduct formed during the synthesis of a fluorinated ether |
US4874901A (en) * | 1988-05-06 | 1989-10-17 | Boc, Inc. | Process for the production of polyfluorinated ethers |
US4874902A (en) * | 1988-05-20 | 1989-10-17 | Boc, Inc. | Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether |
US4996371A (en) * | 1990-01-16 | 1991-02-26 | Boc, Inc. | Method for fluorodecarboxylation |
GB9023370D0 (en) * | 1990-10-26 | 1990-12-05 | Rhone Poulenc Chemicals | Synthesis of fluorinated substituted ethanes |
US5969193A (en) * | 1997-08-18 | 1999-10-19 | Medeva Pharmaceuticals Pa, Inc. | Method for the preparation of sevoflurane |
US5886239A (en) * | 1997-11-21 | 1999-03-23 | Baxter International Inc. | Method of preparing monofluoromethyl ethers |
-
1997
- 1997-08-18 US US08/912,520 patent/US5969193A/en not_active Expired - Lifetime
-
1998
- 1998-08-18 AT AT98306585T patent/ATE219040T1/de not_active IP Right Cessation
- 1998-08-18 EP EP98306585A patent/EP0901999B1/de not_active Revoked
- 1998-08-18 JP JP23131898A patent/JP4166870B2/ja not_active Expired - Fee Related
- 1998-08-18 DE DE69805926T patent/DE69805926T2/de not_active Revoked
- 1998-08-26 ES ES98306858T patent/ES2155278T3/es not_active Expired - Lifetime
-
1999
- 1999-06-21 US US09/337,019 patent/US20010056213A1/en not_active Abandoned
-
2002
- 2002-07-11 US US10/193,786 patent/US20020177739A1/en not_active Abandoned
-
2003
- 2003-08-20 US US10/644,500 patent/US7202386B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5969193A (en) | 1999-10-19 |
DE69805926T2 (de) | 2002-09-26 |
US20020177739A1 (en) | 2002-11-28 |
ATE219040T1 (de) | 2002-06-15 |
JPH11116521A (ja) | 1999-04-27 |
US7202386B2 (en) | 2007-04-10 |
JP4166870B2 (ja) | 2008-10-15 |
EP0901999B1 (de) | 2002-06-12 |
EP0901999A1 (de) | 1999-03-17 |
US20010056213A1 (en) | 2001-12-27 |
ES2155278T3 (es) | 2001-05-01 |
US20040087817A1 (en) | 2004-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8331 | Complete revocation |