ATE207482T1 - Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden - Google Patents

Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden

Info

Publication number
ATE207482T1
ATE207482T1 AT97113390T AT97113390T ATE207482T1 AT E207482 T1 ATE207482 T1 AT E207482T1 AT 97113390 T AT97113390 T AT 97113390T AT 97113390 T AT97113390 T AT 97113390T AT E207482 T1 ATE207482 T1 AT E207482T1
Authority
AT
Austria
Prior art keywords
arginine
arylsulfonyl
nitro
hydrogen atom
lower alkyl
Prior art date
Application number
AT97113390T
Other languages
English (en)
Inventor
Ryoji Kikumoto
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16550431&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE207482(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Application granted granted Critical
Publication of ATE207482T1 publication Critical patent/ATE207482T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT97113390T 1996-08-07 1997-08-04 Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden ATE207482T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20808796 1996-08-07

Publications (1)

Publication Number Publication Date
ATE207482T1 true ATE207482T1 (de) 2001-11-15

Family

ID=16550431

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97113390T ATE207482T1 (de) 1996-08-07 1997-08-04 Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden

Country Status (5)

Country Link
US (1) US5925760A (de)
EP (1) EP0823430B1 (de)
AT (1) ATE207482T1 (de)
DE (1) DE69707603T2 (de)
ES (1) ES2166937T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100465161C (zh) * 2006-11-10 2009-03-04 天津市炜杰科技有限公司 阿加曲班中间体的制备方法
ITPD20080106A1 (it) 2008-04-07 2009-10-08 Lundbeck Pharmaceuticals Italy Spa Metodo di preparazione di argatroban monoidrato
ITMI20110545A1 (it) 2011-04-04 2012-10-05 Lundbeck Pharmaceuticals Italy S P A Metodo per la preparazione di intermedi di processo per la sintesi di argatroban monoidrato
CN104672132B (zh) * 2013-11-28 2017-06-16 四川科瑞德制药股份有限公司 阿加曲班中间体的合成方法
CN109912570A (zh) * 2019-04-04 2019-06-21 天津药物研究院药业有限责任公司 一种阿加曲班中间体酰胺化物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4101653A (en) * 1974-11-08 1978-07-18 Mitsubishi Chemical Industries Limited N2 -arylsulfonyl-argininamides and the pharmaceutically acceptable salts thereof
IE48623B1 (en) * 1978-08-31 1985-03-20 Mitsubishi Chem Ind Alpha-(n-arylsulfonyl-l-argininamides,processes for their preparation and pharmaceutical compositions containing these substances
JPS60163855A (ja) * 1984-02-06 1985-08-26 Mitsubishi Chem Ind Ltd アルギニン誘導体および薬剤として許容され得るその酸付加塩
GB9505538D0 (en) * 1995-03-18 1995-05-03 Ciba Geigy Ag New compounds

Also Published As

Publication number Publication date
EP0823430B1 (de) 2001-10-24
DE69707603D1 (de) 2001-11-29
DE69707603T2 (de) 2002-07-11
ES2166937T3 (es) 2002-05-01
US5925760A (en) 1999-07-20
EP0823430A1 (de) 1998-02-11

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Legal Events

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