BG64278B1 - 2--ианиминоимидазолови производни, 'ъ''ав, м...'оди за пол"-аван...'о им и 'яхно'о използван... - Google Patents
2--ианиминоимидазолови производни, 'ъ''ав, м...'оди за пол"-аван...'о им и 'яхно'о използван... Download PDFInfo
- Publication number
- BG64278B1 BG64278B1 BG103220A BG10322099A BG64278B1 BG 64278 B1 BG64278 B1 BG 64278B1 BG 103220 A BG103220 A BG 103220A BG 10322099 A BG10322099 A BG 10322099A BG 64278 B1 BG64278 B1 BG 64278B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl
- substituted
- formula
- hydrogen
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96202749 | 1996-10-02 | ||
| PCT/EP1997/005322 WO1998014432A1 (en) | 1996-10-02 | 1997-09-24 | Pde iv inhibiting 2-cyanoiminoimidazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG103220A BG103220A (en) | 1999-11-30 |
| BG64278B1 true BG64278B1 (bg) | 2004-08-31 |
Family
ID=8224456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103220A BG64278B1 (bg) | 1996-10-02 | 1999-03-01 | 2--ианиминоимидазолови производни, 'ъ''ав, м...'оди за пол"-аван...'о им и 'яхно'о използван... |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6051718A (de) |
| EP (1) | EP0934280B1 (de) |
| JP (1) | JP3068208B2 (de) |
| KR (1) | KR100520002B1 (de) |
| CN (1) | CN1106387C (de) |
| AR (1) | AR008875A1 (de) |
| AT (1) | ATE236884T1 (de) |
| AU (1) | AU719561B2 (de) |
| BG (1) | BG64278B1 (de) |
| BR (1) | BR9712256B1 (de) |
| CA (1) | CA2267322C (de) |
| CY (1) | CY2380B1 (de) |
| CZ (1) | CZ297474B6 (de) |
| DE (1) | DE69720757T2 (de) |
| DK (1) | DK0934280T3 (de) |
| EE (1) | EE03825B1 (de) |
| ES (1) | ES2196308T3 (de) |
| HK (1) | HK1020344A1 (de) |
| HU (1) | HU225158B1 (de) |
| IL (2) | IL129298A0 (de) |
| MY (1) | MY116980A (de) |
| NO (1) | NO312960B1 (de) |
| NZ (1) | NZ334971A (de) |
| PL (1) | PL194673B1 (de) |
| PT (1) | PT934280E (de) |
| RU (1) | RU2180902C2 (de) |
| SI (1) | SI0934280T1 (de) |
| SK (1) | SK285878B6 (de) |
| TR (1) | TR199900732T2 (de) |
| UA (1) | UA62939C2 (de) |
| WO (1) | WO1998014432A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69912590T2 (de) | 1998-04-01 | 2004-09-16 | Janssen Pharmaceutica N.V. | Pde-iv-hemmende pyridin-derivate |
| US6953774B2 (en) | 2000-08-11 | 2005-10-11 | Applied Research Systems Ars Holding N.V. | Methods of inducing ovulation |
| US20040242627A1 (en) | 2001-04-19 | 2004-12-02 | Shuichi Suzuki | 2-Iminoimidazole derivatives (1) |
| KR20040007583A (ko) | 2001-05-23 | 2004-01-24 | 다나베 세이야꾸 가부시키가이샤 | 연골 질환의 재생치료용 조성물 |
| WO2003006000A1 (fr) * | 2001-07-11 | 2003-01-23 | Nikken Chemicals Co., Ltd. | Remedes pour maladies oculaires allergiques |
| TWI221838B (en) | 2001-08-09 | 2004-10-11 | Tanabe Seiyaku Co | Pyrazinoisoquinoline compound or naphthalene compound |
| ATE526013T1 (de) | 2001-12-14 | 2011-10-15 | Merck Serono Sa | Verfahren zur herbeiführung einer ovulation über einen nicht-polypeptid-camp-spiegel-modulator |
| AU2004218187C1 (en) | 2003-02-19 | 2011-04-07 | Eisai R&D Management Co., Ltd. | Methods for producing cyclic benzamidine derivatives |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| EP2258359A3 (de) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin |
| AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2377531A2 (de) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenese mittels Angiotensin-Modulation |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP2804603A1 (de) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Betazellen-replikation für promoterverbindungen und verwendungsverfahren dafür |
| CA2875964C (en) * | 2012-06-07 | 2018-01-02 | Georgia State University Research Foundation, Inc. | Seca inhibitors and methods of making and using thereof |
| GB2533925A (en) * | 2014-12-31 | 2016-07-13 | Univ Bath | Antimicrobial compounds, compositions and methods |
| CN109438434B (zh) * | 2018-11-19 | 2021-05-04 | 华南农业大学 | 一种含噁唑环的2-氰基亚氨基噻唑烷类化合物及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0784461B2 (ja) * | 1986-12-19 | 1995-09-13 | 日本バイエルアグロケム株式会社 | 殺虫性ニトロイミノ又はシアノイミノ化合物 |
| JPH05310650A (ja) * | 1991-08-22 | 1993-11-22 | Nippon Soda Co Ltd | 新規なアミン誘導体、その製造方法及び殺虫剤 |
| CA2140441C (en) * | 1992-07-28 | 2006-11-21 | Garry Fenton | Inhibitors of c-amp phosphodiesterase and tnf |
| CZ141795A3 (en) * | 1992-12-02 | 1995-11-15 | Pfizer | 4-substituted catechol diethers as such and for treating diseases and pharmaceutical preparations based thereon |
| GB9304919D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| CA2160928C (en) * | 1993-07-28 | 2005-07-05 | Garry Fenton | Compounds as pde iv and tnf inhibitors |
| JPH09502170A (ja) * | 1993-08-19 | 1997-03-04 | スミスクライン・ビーチャム・コーポレイション | フェネチルアミン化合物 |
| GB9401460D0 (en) * | 1994-01-26 | 1994-03-23 | Rhone Poulenc Rorer Ltd | Compositions of matter |
| DE69526790T2 (de) * | 1994-06-24 | 2003-03-06 | Euro Celtique Sa | Verbindungen zur hemmung von phosphodiesrerase iv |
| TW424087B (en) * | 1995-04-06 | 2001-03-01 | Janssen Pharmaceutica Nv | 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives |
| TW375612B (en) * | 1995-04-06 | 1999-12-01 | Janssen Pharmaceutica Nv | 1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same |
| TW332201B (en) * | 1995-04-06 | 1998-05-21 | Janssen Pharmaceutica Nv | 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives |
-
1997
- 1997-09-24 PL PL97332573A patent/PL194673B1/pl unknown
- 1997-09-24 WO PCT/EP1997/005322 patent/WO1998014432A1/en active IP Right Grant
- 1997-09-24 CZ CZ0102899A patent/CZ297474B6/cs not_active IP Right Cessation
- 1997-09-24 CA CA002267322A patent/CA2267322C/en not_active Expired - Lifetime
- 1997-09-24 SK SK344-99A patent/SK285878B6/sk not_active IP Right Cessation
- 1997-09-24 TR TR1999/00732T patent/TR199900732T2/xx unknown
- 1997-09-24 SI SI9730550T patent/SI0934280T1/xx unknown
- 1997-09-24 PT PT97910380T patent/PT934280E/pt unknown
- 1997-09-24 UA UA99031702A patent/UA62939C2/uk unknown
- 1997-09-24 DE DE69720757T patent/DE69720757T2/de not_active Expired - Lifetime
- 1997-09-24 EE EEP199900112A patent/EE03825B1/xx unknown
- 1997-09-24 CN CN97198460A patent/CN1106387C/zh not_active Expired - Lifetime
- 1997-09-24 DK DK97910380T patent/DK0934280T3/da active
- 1997-09-24 NZ NZ334971A patent/NZ334971A/xx not_active IP Right Cessation
- 1997-09-24 AU AU47792/97A patent/AU719561B2/en not_active Expired
- 1997-09-24 AT AT97910380T patent/ATE236884T1/de active
- 1997-09-24 US US09/147,925 patent/US6051718A/en not_active Expired - Lifetime
- 1997-09-24 HU HU9904063A patent/HU225158B1/hu unknown
- 1997-09-24 EP EP97910380A patent/EP0934280B1/de not_active Expired - Lifetime
- 1997-09-24 KR KR10-1999-7001204A patent/KR100520002B1/ko not_active IP Right Cessation
- 1997-09-24 JP JP10516215A patent/JP3068208B2/ja not_active Expired - Lifetime
- 1997-09-24 RU RU99109032/04A patent/RU2180902C2/ru active
- 1997-09-24 BR BRPI9712256-4A patent/BR9712256B1/pt not_active IP Right Cessation
- 1997-09-24 IL IL12929897A patent/IL129298A0/xx active IP Right Grant
- 1997-09-24 ES ES97910380T patent/ES2196308T3/es not_active Expired - Lifetime
- 1997-10-01 AR ARP970104528A patent/AR008875A1/es active IP Right Grant
- 1997-10-02 MY MYPI97004600A patent/MY116980A/en unknown
-
1999
- 1999-03-01 BG BG103220A patent/BG64278B1/bg unknown
- 1999-03-30 NO NO19991560A patent/NO312960B1/no not_active IP Right Cessation
- 1999-03-31 IL IL129298A patent/IL129298A/en not_active IP Right Cessation
- 1999-11-27 HK HK99105520A patent/HK1020344A1/xx not_active IP Right Cessation
-
2003
- 2003-11-04 CY CY0300074A patent/CY2380B1/xx unknown
Also Published As
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| BG64278B1 (bg) | 2--ианиминоимидазолови производни, 'ъ''ав, м...'оди за пол"-аван...'о им и 'яхно'о използван... | |
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