BG63573B1 - Теломераза при бозайници - Google Patents
Теломераза при бозайници Download PDFInfo
- Publication number
- BG63573B1 BG63573B1 BG101103A BG10110397A BG63573B1 BG 63573 B1 BG63573 B1 BG 63573B1 BG 101103 A BG101103 A BG 101103A BG 10110397 A BG10110397 A BG 10110397A BG 63573 B1 BG63573 B1 BG 63573B1
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- BG
- Bulgaria
- Prior art keywords
- telomerase
- rna component
- sequence
- rna
- human
- Prior art date
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Mechanical Engineering (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Extrusion Moulding Of Plastics Or The Like (AREA)
- Shaping Of Tube Ends By Bending Or Straightening (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27210294A | 1994-07-07 | 1994-07-07 | |
| US08/330,123 US5583016A (en) | 1994-07-07 | 1994-10-27 | Mammalian telomerase |
| US08/482,115 US5776679A (en) | 1994-07-07 | 1995-06-07 | Assays for the DNA component of human telomerase |
| US08/472,802 US5958680A (en) | 1994-07-07 | 1995-06-07 | Mammalian telomerase |
| PCT/US1995/008530 WO1996001835A1 (en) | 1994-07-07 | 1995-07-06 | Mammalian telomerase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG101103A BG101103A (en) | 1997-10-31 |
| BG63573B1 true BG63573B1 (bg) | 2002-05-31 |
Family
ID=27501040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG101103A BG63573B1 (bg) | 1994-07-07 | 1997-01-04 | Теломераза при бозайници |
Country Status (23)
| Country | Link |
|---|---|
| EP (2) | EP0778842B1 (es) |
| JP (2) | JPH10505488A (es) |
| KR (1) | KR100789741B1 (es) |
| CN (1) | CN1231491C (es) |
| AT (1) | ATE308554T1 (es) |
| AU (1) | AU696702B2 (es) |
| BG (1) | BG63573B1 (es) |
| BR (1) | BR9508254A (es) |
| CA (1) | CA2194393C (es) |
| CZ (1) | CZ3497A3 (es) |
| DE (1) | DE69534568T2 (es) |
| DK (1) | DK0778842T3 (es) |
| ES (1) | ES2251720T3 (es) |
| FI (1) | FI970026A (es) |
| HK (1) | HK1011691A1 (es) |
| HU (1) | HUT78054A (es) |
| IS (1) | IS4408A (es) |
| NO (1) | NO970041L (es) |
| NZ (1) | NZ289720A (es) |
| PL (1) | PL181019B1 (es) |
| RO (1) | RO117328B1 (es) |
| UA (1) | UA47407C2 (es) |
| WO (1) | WO1996001835A1 (es) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7067497B2 (en) | 1992-09-29 | 2006-06-27 | Isis Pharmaceuticals, Inc. | Modulation of telomere length by oligonucleotides having a G-core sequence |
| US5972605A (en) * | 1994-07-07 | 1999-10-26 | Geron Corporation | Assays for regulators of mammalian telomerase expression |
| US5958680A (en) | 1994-07-07 | 1999-09-28 | Geron Corporation | Mammalian telomerase |
| US5968506A (en) * | 1995-08-04 | 1999-10-19 | Geron Corporation | Purified telomerase |
| US6545133B1 (en) | 1995-08-04 | 2003-04-08 | Geron Corporation | Methods for purifying telomerase |
| US6517834B1 (en) | 1995-08-04 | 2003-02-11 | Geron Corporation | Purified telomerase |
| US5858777A (en) | 1995-09-08 | 1999-01-12 | Geron Corporation | Methods and reagents for regulating telomere length and telomerase activity |
| ATE219151T1 (de) * | 1995-11-16 | 2002-06-15 | Michael W Dahm | Verfahren zur quantifizierung von tumorzellen in einer körperflüssigkeit und dazu geeignete testkits |
| WO1997035967A2 (en) * | 1996-03-28 | 1997-10-02 | Cold Spring Harbor Laboratory | Transgenic organisms with altered telomerase activity |
| US6015710A (en) * | 1996-04-09 | 2000-01-18 | The University Of Texas System | Modulation of mammalian telomerase by peptide nucleic acids |
| JPH1052300A (ja) * | 1996-06-03 | 1998-02-24 | Kyowa Hakko Kogyo Co Ltd | 細胞内テロメラーゼ活性の測定法 |
| JPH1028600A (ja) * | 1996-07-17 | 1998-02-03 | Kyowa Hakko Kogyo Co Ltd | テロメラーゼ活性の測定法 |
| US6093809A (en) | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| GB2321642B8 (en) | 1996-10-01 | 2006-08-22 | Geron Corp | Human telomerase reverse transcriptase promoter |
| US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
| US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| US6808880B2 (en) | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
| US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
| US7390891B1 (en) * | 1996-11-15 | 2008-06-24 | Amgen Inc. | Polynucleotides encoding a telomerase component TP2 |
| US5919656A (en) * | 1996-11-15 | 1999-07-06 | Amgen Canada Inc. | Genes encoding telomerase protein 1 |
| US5846723A (en) * | 1996-12-20 | 1998-12-08 | Geron Corporation | Methods for detecting the RNA component of telomerase |
| WO1998028442A1 (en) * | 1996-12-20 | 1998-07-02 | Geron Corporation | Methods for detecting and inhibiting the rna component of telomerase |
| WO1998037181A2 (en) * | 1997-02-20 | 1998-08-27 | Whitehead Institute For Biomedical Research | Telomerase catalytic subunit gene and encoded protein |
| WO1998045450A1 (en) * | 1997-04-04 | 1998-10-15 | Geron Corporation | Purified telomerase |
| US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
| US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
| AU745420B2 (en) * | 1997-06-20 | 2002-03-21 | Bayer Aktiengesellschaft | Human catalytic telomerase sub-unit and its diagnostic and therapeutic use |
| EP1571215A3 (en) * | 1997-07-01 | 2007-10-31 | Cambia Biosystems LLC | Vertebrate telomerase genes and proteins and uses thereof |
| CN1270634A (zh) * | 1997-07-01 | 2000-10-18 | 卡姆比亚生物系统有限责任公司 | 脊椎动物端粒酶基因和蛋白质及其用途 |
| US7378244B2 (en) | 1997-10-01 | 2008-05-27 | Geron Corporation | Telomerase promoters sequences for screening telomerase modulators |
| DE19757300A1 (de) * | 1997-12-22 | 1999-06-24 | Roche Diagnostics Gmbh | Nachweis von Harnblasenkarzinom in einer Urinprobe |
| GB9801902D0 (en) * | 1998-01-29 | 1998-03-25 | Cancer Res Campaign Tech | A gene promoter |
| DE19804372A1 (de) | 1998-02-04 | 1999-08-05 | Michael W Dr Dr Dahm | Verfahren zur quantitativen Bestimmung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits |
| US7402307B2 (en) * | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
| US6358739B1 (en) * | 1999-04-12 | 2002-03-19 | Modex Therapeutiques, S.A. | Transiently immortalized cells |
| WO2000074667A2 (en) * | 1999-06-04 | 2000-12-14 | Au Jessie L S | Compositions active in telomere damage comprising a taxane and telomerase inhibitor |
| US6995145B1 (en) | 1999-06-04 | 2006-02-07 | Au Jessie L-S | Methods and compositions for modulating drug activity through telomere damage |
| EP1992634A1 (en) | 1999-09-10 | 2008-11-19 | Geron Corporation | Oligonucleotide n3'- p5' thiophosphoramidates: their synthesis and use |
| AU1309101A (en) * | 1999-11-16 | 2001-05-30 | Kyowa Hakko Kogyo Co. Ltd. | Method of searching for substance inhibiting binding between telomerase subunits |
| AP2280A (en) * | 2003-06-23 | 2011-10-31 | Geron Corp | Compositions and methods for increasing telomeraseactivity. |
| BRPI0414222B8 (pt) | 2003-09-09 | 2021-05-25 | Geron Corp | compostos oligonucleotídeos modificados para inibição da telomerase, métodos, composição farmacêutica e usos relacionados |
| JP4635196B2 (ja) * | 2005-03-04 | 2011-02-16 | 国立大学法人広島大学 | 遺伝子導入細胞、及びそれを用いたテロメラーゼ誘導物質の検出方法 |
| WO2008094640A2 (en) | 2007-01-30 | 2008-08-07 | Geron Corporation | Compounds having anti-adhesive effects on cancer cells |
| AU2010239131A1 (en) | 2009-04-21 | 2011-11-17 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
| WO2012165653A1 (ja) * | 2011-05-30 | 2012-12-06 | 国立大学法人豊橋技術科学大学 | 改良されたオリゴヌクレオチドおよびそのオリゴヌクレオチドを含む医薬組成物 |
| US20150125438A1 (en) * | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
| US9200327B2 (en) | 2012-11-30 | 2015-12-01 | Geron Corporation | Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors |
| JP6556728B2 (ja) * | 2013-09-13 | 2019-08-07 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ポリＡ−キャリヤーにより誘導される高分子量ＰＣＲ生成物の生成を避けるためのオリゴ−ｄＴ分子の適用 |
| JOP20200257A1 (ar) | 2014-05-01 | 2017-06-16 | Geron Corp | تركيبات أوليجو نوكليوتيد وطرق لتحضيرها |
| KR101628890B1 (ko) * | 2015-09-03 | 2016-06-09 | 주식회사 학표벽지 | 엠보싱 벽지 제조 장치 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4312686A (en) * | 1980-02-11 | 1982-01-26 | American Biltrite Inc. | Printed and embossed floor covering and method and apparatus for its manufacture |
| JPH02179729A (ja) * | 1988-12-30 | 1990-07-12 | Shinetsu Kogyo Kk | ゲートル巻きするラッピングフィルムの製造法 |
| US5489508A (en) * | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
| WO1995013382A1 (en) * | 1993-11-12 | 1995-05-18 | Geron Corporation | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
| EP0666313A3 (en) * | 1994-01-27 | 1996-03-06 | Univ Iowa State Res Found Inc | Targeting telomerase in gene therapy for cancer. |
| US5876979A (en) * | 1994-07-07 | 1999-03-02 | Cold Spring Harbor Laboratory | RNA component of mouse, rat, Chinese hamster and bovine telomerase |
| JPH08294966A (ja) * | 1995-04-26 | 1996-11-12 | Nippon Shokubai Co Ltd | 樹脂成形品の連続成形方法 |
| JPH10119130A (ja) | 1996-10-22 | 1998-05-12 | Japan Steel Works Ltd:The | 連続発泡体の製造方法及び装置 |
| KR100815605B1 (ko) * | 2002-02-18 | 2008-03-20 | 바프렉스 주식회사 | 공압출 다층필름의 제조방법 및 장치 |
-
1995
- 1995-07-06 AT AT95925552T patent/ATE308554T1/de active
- 1995-07-06 RO RO97-00016A patent/RO117328B1/ro unknown
- 1995-07-06 AU AU29647/95A patent/AU696702B2/en not_active Expired
- 1995-07-06 NZ NZ289720A patent/NZ289720A/xx not_active IP Right Cessation
- 1995-07-06 EP EP95925552A patent/EP0778842B1/en not_active Expired - Lifetime
- 1995-07-06 DK DK95925552T patent/DK0778842T3/da active
- 1995-07-06 DE DE69534568T patent/DE69534568T2/de not_active Expired - Lifetime
- 1995-07-06 CZ CZ9734A patent/CZ3497A3/cs unknown
- 1995-07-06 PL PL95318169A patent/PL181019B1/pl unknown
- 1995-07-06 EP EP02080023A patent/EP1293565A3/en not_active Withdrawn
- 1995-07-06 ES ES95925552T patent/ES2251720T3/es not_active Expired - Lifetime
- 1995-07-06 HU HU9700035A patent/HUT78054A/hu unknown
- 1995-07-06 UA UA97010079A patent/UA47407C2/uk unknown
- 1995-07-06 WO PCT/US1995/008530 patent/WO1996001835A1/en active IP Right Grant
- 1995-07-06 CA CA002194393A patent/CA2194393C/en not_active Expired - Lifetime
- 1995-07-06 CN CNB951949527A patent/CN1231491C/zh not_active Expired - Lifetime
- 1995-07-06 BR BR9508254A patent/BR9508254A/pt not_active IP Right Cessation
- 1995-07-06 JP JP8504403A patent/JPH10505488A/ja not_active Withdrawn
-
1997
- 1997-01-03 IS IS4408A patent/IS4408A/is unknown
- 1997-01-03 FI FI970026A patent/FI970026A/fi unknown
- 1997-01-04 BG BG101103A patent/BG63573B1/bg unknown
- 1997-01-06 NO NO970041A patent/NO970041L/no not_active Application Discontinuation
-
1998
- 1998-11-30 HK HK98112580A patent/HK1011691A1/xx not_active IP Right Cessation
-
2002
- 2002-03-06 JP JP2002061125A patent/JP4068861B2/ja not_active Expired - Lifetime
-
2003
- 2003-12-11 KR KR1020030090113A patent/KR100789741B1/ko active IP Right Grant
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