BG63259B1 - Тропан-2-алдоксинови производни като невротрансмитерни инхибитори на обратното поемане (реъптейк) - Google Patents
Тропан-2-алдоксинови производни като невротрансмитерни инхибитори на обратното поемане (реъптейк) Download PDFInfo
- Publication number
- BG63259B1 BG63259B1 BG100883A BG10088396A BG63259B1 BG 63259 B1 BG63259 B1 BG 63259B1 BG 100883 A BG100883 A BG 100883A BG 10088396 A BG10088396 A BG 10088396A BG 63259 B1 BG63259 B1 BG 63259B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- tropan
- dichlorophenyl
- aldoxime
- cycloalkyl
- alkyl
- Prior art date
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- YHWZJYKIOUHJGH-CAOSSQGBSA-N methyl (1s,3s,4r,5r)-3-benzyl-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C([C@@H]1[C@H]([C@]2(CC[C@@](C1)(N2C)[H])[H])C(=O)OC)C1=CC=CC=C1 YHWZJYKIOUHJGH-CAOSSQGBSA-N 0.000 description 1
- YHWZJYKIOUHJGH-JONQDZQNSA-N methyl (1s,3s,4s,5r)-3-benzyl-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C([C@@H]1[C@@H]([C@]2(CC[C@@](C1)(N2C)[H])[H])C(=O)OC)C1=CC=CC=C1 YHWZJYKIOUHJGH-JONQDZQNSA-N 0.000 description 1
- WXEMSGQRTGSYOG-PMDVUHRTSA-N methyl (1s,5r)-8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1C(=O)C(C(=O)OC)[C@@]2([H])CC[C@]1([H])N2C WXEMSGQRTGSYOG-PMDVUHRTSA-N 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 125000002950 monocyclic group Chemical group 0.000 description 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
- KVBGVZZKJNLNJU-UHFFFAOYSA-N naphthalene-2-sulfonic acid Chemical compound C1=CC=CC2=CC(S(=O)(=O)O)=CC=C21 KVBGVZZKJNLNJU-UHFFFAOYSA-N 0.000 description 1
- 235000021096 natural sweeteners Nutrition 0.000 description 1
- 230000010807 negative regulation of binding Effects 0.000 description 1
- 210000001577 neostriatum Anatomy 0.000 description 1
- 239000003176 neuroleptic agent Substances 0.000 description 1
- 229960001158 nortriptyline Drugs 0.000 description 1
- 210000001009 nucleus accumben Anatomy 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 125000004287 oxazol-2-yl group Chemical group [H]C1=C([H])N=C(*)O1 0.000 description 1
- 125000003145 oxazol-4-yl group Chemical group O1C=NC(=C1)* 0.000 description 1
- 125000004304 oxazol-5-yl group Chemical group O1C=NC=C1* 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000006201 parenteral dosage form Substances 0.000 description 1
- 239000003182 parenteral nutrition solution Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 description 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 230000001242 postsynaptic effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000003518 presynaptic effect Effects 0.000 description 1
- ALDITMKAAPLVJK-UHFFFAOYSA-N prop-1-ene;hydrate Chemical group O.CC=C ALDITMKAAPLVJK-UHFFFAOYSA-N 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N propylene glycol Substances CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 1
- 238000000159 protein binding assay Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229960002601 protriptyline Drugs 0.000 description 1
- BWPIARFWQZKAIA-UHFFFAOYSA-N protriptyline Chemical compound C1=CC2=CC=CC=C2C(CCCNC)C2=CC=CC=C21 BWPIARFWQZKAIA-UHFFFAOYSA-N 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000012312 sodium hydride Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 229940086735 succinate Drugs 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 230000003319 supportive effect Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 150000003899 tartaric acid esters Chemical class 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 125000000437 thiazol-2-yl group Chemical group [H]C1=C([H])N=C(*)S1 0.000 description 1
- 125000004495 thiazol-4-yl group Chemical group S1C=NC(=C1)* 0.000 description 1
- 125000004496 thiazol-5-yl group Chemical group S1C=NC=C1* 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- NAUWTFJOPJWYOT-UHFFFAOYSA-N vanoxerine Chemical compound C1=CC(F)=CC=C1C(C=1C=CC(F)=CC=1)OCCN1CCN(CCCC=2C=CC=CC=2)CC1 NAUWTFJOPJWYOT-UHFFFAOYSA-N 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK44794 | 1994-04-19 | ||
| DK133894 | 1994-11-24 | ||
| PCT/EP1995/001358 WO1995028401A1 (en) | 1994-04-19 | 1995-04-12 | Tropane-2-aldoxine derivatives as neurotransmitter reuptake inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG100883A BG100883A (en) | 1998-03-31 |
| BG63259B1 true BG63259B1 (bg) | 2001-07-31 |
Family
ID=26064021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG100883A BG63259B1 (bg) | 1994-04-19 | 1996-10-02 | Тропан-2-алдоксинови производни като невротрансмитерни инхибитори на обратното поемане (реъптейк) |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5736556A (cs) |
| EP (1) | EP0756596B1 (cs) |
| JP (1) | JP2899418B2 (cs) |
| KR (1) | KR100210417B1 (cs) |
| CN (1) | CN1043763C (cs) |
| AT (1) | ATE222587T1 (cs) |
| AU (1) | AU690257B2 (cs) |
| BG (1) | BG63259B1 (cs) |
| BR (1) | BR9507489A (cs) |
| CA (1) | CA2187309C (cs) |
| CZ (1) | CZ284379B6 (cs) |
| DE (1) | DE69527839T2 (cs) |
| DK (1) | DK0756596T3 (cs) |
| EE (1) | EE03877B1 (cs) |
| FI (1) | FI965074A0 (cs) |
| GE (1) | GEP19991749B (cs) |
| HU (1) | HU215830B (cs) |
| LV (1) | LV11738B (cs) |
| NO (1) | NO964180L (cs) |
| NZ (1) | NZ284075A (cs) |
| PL (1) | PL183025B1 (cs) |
| RU (1) | RU2134264C1 (cs) |
| SK (1) | SK280875B6 (cs) |
| UA (1) | UA49801C2 (cs) |
| WO (1) | WO1995028401A1 (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69637097T2 (de) * | 1995-10-13 | 2007-09-20 | Neurosearch A/S | 8-Azabicyclo(3.2.1)Oct-2-en-Derivate, deren Herstellung und Anwendung |
| US6241963B1 (en) * | 1995-10-19 | 2001-06-05 | The Trustees Of The University Of Pennsylvania | Dopamine and serotonin transporter ligands and imaging agents |
| SK282944B6 (sk) * | 1995-11-02 | 2003-01-09 | Neurosearch A/S | Tavené tropánové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie |
| US5948933A (en) * | 1997-07-11 | 1999-09-07 | Organix, Inc. | Tropane analogs and methods for inhibition of monoamine transport |
| DK0885220T3 (da) * | 1996-02-22 | 2001-10-15 | Neurosearch As | Tropanderivater, deres fresmtilling og anvendelse |
| US6232326B1 (en) | 1998-07-14 | 2001-05-15 | Jodi A. Nelson | Treatment for schizophrenia and other dopamine system dysfunctions |
| US20040229908A1 (en) * | 1999-07-13 | 2004-11-18 | Jodi Nelson | Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias |
| WO2001003649A2 (en) | 1999-07-13 | 2001-01-18 | Alpha Research Group, Llc | Compositions and methods for the treatment of parkinson's disease |
| DE60135685D1 (de) * | 2000-05-26 | 2008-10-16 | Pfizer | Triazolyltropanderivate als ccr5-modulatoren |
| US6667314B2 (en) | 2000-05-26 | 2003-12-23 | Pfizer, Inc. | Tropane derivatives useful in therapy |
| US20040106643A1 (en) * | 2001-05-23 | 2004-06-03 | Gouliaev Alex Haarh | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| US6610849B2 (en) * | 2001-06-28 | 2003-08-26 | Boehringer Ingelheim Pharma Kg | Process for the manufacture of tropenol |
| EP1453511B1 (en) * | 2001-11-30 | 2006-11-15 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| DE10200943A1 (de) * | 2002-01-12 | 2003-07-24 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Scopinestern |
| CA2480742A1 (en) * | 2002-03-28 | 2003-12-04 | President And Fellows Of Harvard College | Tropane compounds |
| MXPA06003749A (es) | 2003-10-03 | 2006-06-14 | Pfizer | Derivados de tropano. |
| EP1675591B1 (en) * | 2003-10-16 | 2011-08-10 | NeuroSearch A/S | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor |
| WO2005070429A1 (en) * | 2004-01-22 | 2005-08-04 | Neurosearch A/S | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an n-methyl-d-aspartate (nmda) receptors antagonist |
| JP2007519646A (ja) * | 2004-01-22 | 2007-07-19 | ノイロサーチ アクティーゼルスカブ | 体重の持続的低減のための化合物 |
| RU2352332C1 (ru) * | 2005-01-14 | 2009-04-20 | Частное Предприятие "Славянская Клиника" | Применение местного анестетика для коррекции пищевого поведения человека и способ применения |
| EP1779851A1 (en) | 2005-10-31 | 2007-05-02 | Boehringer Ingelheim Pharma GmbH & Co.KG | Treatment of diabetes |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3813404A (en) * | 1972-11-15 | 1974-05-28 | Sterling Drug Inc | Tropane-2-carboxylates and derivatives |
| SU941369A1 (ru) * | 1978-12-29 | 1982-07-07 | Научно-исследовательский институт фармакологии АМН СССР | Хлоргидраты W-аминоацильных эфиров тропан-3-ола как стимул торы центральной нервной системы |
| AT397962B (de) * | 1985-12-27 | 1994-08-25 | Madaus & Co Dr | Verfahren zur herstellung von azoniaspironortropanolestern |
| AU671163B2 (en) * | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
| AU672052B2 (en) * | 1992-12-23 | 1996-09-19 | Neurosearch A/S | Antidepressant and antiparkinsonian compounds |
-
1995
- 1995-04-12 UA UA96103884A patent/UA49801C2/uk unknown
- 1995-04-12 KR KR1019960705823A patent/KR100210417B1/ko not_active Expired - Fee Related
- 1995-04-12 PL PL95316876A patent/PL183025B1/pl unknown
- 1995-04-12 NZ NZ284075A patent/NZ284075A/en unknown
- 1995-04-12 CN CN95193151A patent/CN1043763C/zh not_active Expired - Fee Related
- 1995-04-12 AU AU22575/95A patent/AU690257B2/en not_active Ceased
- 1995-04-12 DE DE69527839T patent/DE69527839T2/de not_active Expired - Lifetime
- 1995-04-12 RU RU96121937A patent/RU2134264C1/ru active
- 1995-04-12 CA CA002187309A patent/CA2187309C/en not_active Expired - Fee Related
- 1995-04-12 EE EE9600132A patent/EE03877B1/xx not_active IP Right Cessation
- 1995-04-12 WO PCT/EP1995/001358 patent/WO1995028401A1/en not_active Ceased
- 1995-04-12 CZ CZ962982A patent/CZ284379B6/cs not_active IP Right Cessation
- 1995-04-12 AT AT95915869T patent/ATE222587T1/de not_active IP Right Cessation
- 1995-04-12 GE GEAP19953459A patent/GEP19991749B/en unknown
- 1995-04-12 US US08/722,010 patent/US5736556A/en not_active Expired - Lifetime
- 1995-04-12 SK SK1288-96A patent/SK280875B6/sk unknown
- 1995-04-12 JP JP7526700A patent/JP2899418B2/ja not_active Expired - Fee Related
- 1995-04-12 BR BR9507489A patent/BR9507489A/pt not_active Application Discontinuation
- 1995-04-12 EP EP95915869A patent/EP0756596B1/en not_active Expired - Lifetime
- 1995-04-12 DK DK95915869T patent/DK0756596T3/da active
- 1995-04-12 HU HU9602707A patent/HU215830B/hu not_active IP Right Cessation
-
1996
- 1996-10-02 BG BG100883A patent/BG63259B1/bg unknown
- 1996-10-02 NO NO964180A patent/NO964180L/no not_active Application Discontinuation
- 1996-11-11 LV LVP-96-428A patent/LV11738B/en unknown
- 1996-12-17 FI FI965074A patent/FI965074A0/fi active IP Right Revival
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