BG51251A3 - Method for the preparetion of tetrahydroimidazo /1,4/-benzodiazepine (?)-2-ketons - Google Patents

Method for the preparetion of tetrahydroimidazo /1,4/-benzodiazepine (?)-2-ketons Download PDF

Info

Publication number
BG51251A3
BG51251A3 BG087682A BG8768289A BG51251A3 BG 51251 A3 BG51251 A3 BG 51251A3 BG 087682 A BG087682 A BG 087682A BG 8768289 A BG8768289 A BG 8768289A BG 51251 A3 BG51251 A3 BG 51251A3
Authority
BG
Bulgaria
Prior art keywords
residue
hydrogen
benzodiazepine
preparetion
ketons
Prior art date
Application number
BG087682A
Other languages
Bulgarian (bg)
English (en)
Inventor
Alfons Raeymaekers
Josephus Ludovicus Gelder
Michael Kukla
Henry Breslin
Paul Adriaan Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BG51251A3 publication Critical patent/BG51251A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG087682A 1988-03-18 1989-03-16 Method for the preparetion of tetrahydroimidazo /1,4/-benzodiazepine (?)-2-ketons BG51251A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888806449A GB8806449D0 (en) 1988-03-18 1988-03-18 Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Publications (1)

Publication Number Publication Date
BG51251A3 true BG51251A3 (en) 1993-03-15

Family

ID=10633662

Family Applications (1)

Application Number Title Priority Date Filing Date
BG087682A BG51251A3 (en) 1988-03-18 1989-03-16 Method for the preparetion of tetrahydroimidazo /1,4/-benzodiazepine (?)-2-ketons

Country Status (26)

Country Link
EP (1) EP0336466B1 (zh)
JP (1) JP2693559B2 (zh)
KR (1) KR0133073B1 (zh)
CN (1) CN1031058C (zh)
AT (1) ATE84035T1 (zh)
AU (2) AU617435B2 (zh)
BG (1) BG51251A3 (zh)
CA (1) CA1310964C (zh)
DE (1) DE68904102T2 (zh)
DK (1) DK130989A (zh)
ES (1) ES2053946T3 (zh)
FI (1) FI89800C (zh)
GB (1) GB8806449D0 (zh)
GR (1) GR3006728T3 (zh)
HU (2) HU206873B (zh)
IE (1) IE63108B1 (zh)
IL (1) IL89633A (zh)
JO (1) JO1589B1 (zh)
MY (1) MY104942A (zh)
NO (1) NO167737C (zh)
NZ (1) NZ228216A (zh)
PH (1) PH27044A (zh)
PT (1) PT90034B (zh)
SU (1) SU1748647A3 (zh)
TN (1) TNSN89039A1 (zh)
ZA (1) ZA892062B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270464A (en) * 1989-03-14 1993-12-14 Janssen Pharmaceutica N.V. Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
NZ235137A (en) * 1989-09-13 1992-02-25 Janssen Pharmaceutica Nv Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
US5164376A (en) * 1989-10-30 1992-11-17 Hoffmann-Laroche Inc. Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
EP0436245A1 (en) * 1989-12-27 1991-07-10 Duphar International Research B.V Substituted 3,4-annelated benzimidazol-2(1H)-ones
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
NZ238664A (en) * 1990-07-06 1992-12-23 Janssen Pharmaceutica Nv Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
DE4036552C1 (zh) * 1990-11-16 1992-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9109557D0 (en) 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
ES2138624T3 (es) * 1992-05-13 2000-01-16 Wellcome Found Combinaciones terapeuticas.
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
KR101589314B1 (ko) 2007-08-20 2016-01-28 에보텍 인터내셔널 게엠베하 수면 장애의 치료

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534257A1 (fr) * 1982-10-12 1984-04-13 Roussel Uclaf Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
KR0133073B1 (en) 1998-04-17
PT90034A (pt) 1989-11-10
AU630575B2 (en) 1992-10-29
CN1036957A (zh) 1989-11-08
GB8806449D0 (en) 1988-04-20
DE68904102D1 (de) 1993-02-11
NO167737C (no) 1991-12-04
JPH01275582A (ja) 1989-11-06
JP2693559B2 (ja) 1997-12-24
IE890851L (en) 1989-09-18
ZA892062B (en) 1990-11-28
PT90034B (pt) 1994-05-31
DK130989D0 (da) 1989-03-17
FI891279A0 (fi) 1989-03-17
CN1031058C (zh) 1996-02-21
KR890014546A (ko) 1989-10-24
AU8360291A (en) 1991-11-07
NO891176L (no) 1989-09-19
HUT52099A (en) 1990-06-28
EP0336466B1 (en) 1992-12-30
IE63108B1 (en) 1995-03-22
MY104942A (en) 1994-07-30
IL89633A0 (en) 1989-09-28
ES2053946T3 (es) 1994-08-01
AU3131089A (en) 1989-09-21
FI89800B (fi) 1993-08-13
NO167737B (no) 1991-08-26
NZ228216A (en) 1991-01-29
DK130989A (da) 1989-09-19
PH27044A (en) 1993-02-01
CA1310964C (en) 1992-12-01
EP0336466A1 (en) 1989-10-11
DE68904102T2 (de) 1993-05-06
NO891176D0 (no) 1989-03-17
FI89800C (fi) 1993-11-25
HU911782D0 (en) 1991-12-30
JO1589B1 (en) 1989-12-16
SU1748647A3 (ru) 1992-07-15
AU617435B2 (en) 1991-11-28
HU206873B (en) 1993-01-28
IL89633A (en) 1994-02-27
HU203757B (en) 1991-09-30
GR3006728T3 (zh) 1993-06-30
ATE84035T1 (de) 1993-01-15
FI891279A (fi) 1989-09-19
TNSN89039A1 (fr) 1991-02-04

Similar Documents

Publication Publication Date Title
ES2070175T3 (es) Derivados de acido 4-oxoquinolino-3-carboxilico, su preparacion y su uso.
BG51251A3 (en) Method for the preparetion of tetrahydroimidazo /1,4/-benzodiazepine (?)-2-ketons
DK114783D0 (da) Hidtil ukendte forbindelser, fremgangsmader til deres fremstilling samt deres anvendelse som laegemidler
FI865269A0 (fi) Kvaevehaltiga heterocykliska foereningar.
AR248135A1 (es) N-amino-1, 2, 4-triazinonas, su preparacion, intermediarios usados en el procedimiento, agentes antiparasitarios derivados de aminotriazinonas y el procedimiento de su obtencion.
DK633088D0 (da) Hidtil ukendte forbindelser
NO170685C (no) Optisk aktive alkyl-aryl-ketaler
ES2057126T3 (es) Metodo de tratamiento de la caquexia y algunos nuevos compuestos para utilizar en este metodo.
ES2087854T3 (es) Nuevos oxatiolanos y derivados de los mismos, composiciones farmaceuticas que los contienen y el uso de los mismos como medicamentos.
SE8604950L (sv) Demensforbettrande och terapeutiska medel
TW240227B (zh)
DE3372364D1 (en) 1-carboxyalkanoylperhydroindole-2-carboxylic acids and derivatives
AR241136A2 (es) Procedimiento para preparar esteres de 6-hidroxi-2-benzotiazolsulfonamida para tratamiento topicode presion intraocular elevada"
ATE44028T1 (de) Kronenaether-derivate.
ATE27806T1 (de) Norbornan- und norbornencarbonsaeureamide und verfahren zu deren herstellung.
AR241502A1 (es) Benzoil-ureas de accion insecticida. preparacion de las mismas. nueva amina aromatica para la preparacion de las benzoil-ureas y preparacion de la misma.
GB1513948A (en) Thiazolidine derivatives and process for their manufactur
HUT50464A (en) Process for producing phenothiazin derivatives
CA1267150C (en) THIABICYCLOHEPTANE SUBSTITUTION DERIVATIVES OF AMINO-PROSTAGLANDIN ANALOGS
CA1267906C (en) PROSTAGLANDIN ANALOGS WITH 7-OXABICYCLOHEPTANE SUBSTITUTE
ES8702392A1 (es) Un procedimiento para preparar compuestos heterociclicos, en particular compuestos con un anillo de tiadiazinona
ATE60779T1 (de) N-glykolylneuraminsaeurederivat.
ES485392A1 (es) Un procedimiento para la preparacion de derivados de amino- alcoholes.
ATE55388T1 (de) Heterocyclische aminoverbindungen.
ATE17000T1 (de) Substituierte azolylethyl-oximinoalkyl-ether, verfahren zu ihrer herstellung und ihre verwendung als fungizide.