NO167737C - Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydroimidazo(1,4)benzodiazepin-2-oner. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydroimidazo(1,4)benzodiazepin-2-oner.

Info

Publication number
NO167737C
NO167737C NO891176A NO891176A NO167737C NO 167737 C NO167737 C NO 167737C NO 891176 A NO891176 A NO 891176A NO 891176 A NO891176 A NO 891176A NO 167737 C NO167737 C NO 167737C
Authority
NO
Norway
Prior art keywords
6alkyl
hydrogen
benzodiazepin
tetrahydroimidazo
oner
Prior art date
Application number
NO891176A
Other languages
English (en)
Other versions
NO167737B (no
NO891176L (no
NO891176D0 (no
Inventor
Alfons Herman Marg Raeymaekers
Josephus Ludovicus Hube Gelder
Michael Joseph Kukla
Henry Joseph Breslin
Paul Adriaan Jan Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO891176D0 publication Critical patent/NO891176D0/no
Publication of NO891176L publication Critical patent/NO891176L/no
Priority to NO911970A priority Critical patent/NO179369C/no
Publication of NO167737B publication Critical patent/NO167737B/no
Publication of NO167737C publication Critical patent/NO167737C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO891176A 1988-03-18 1989-03-17 Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydroimidazo(1,4)benzodiazepin-2-oner. NO167737C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO911970A NO179369C (no) 1988-03-18 1991-05-22 Reaksjonsblanding for fremstilling av antivirale tetrahydroimidazo[1,4Åbenzodiazepin-2-oner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888806449A GB8806449D0 (en) 1988-03-18 1988-03-18 Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Publications (4)

Publication Number Publication Date
NO891176D0 NO891176D0 (no) 1989-03-17
NO891176L NO891176L (no) 1989-09-19
NO167737B NO167737B (no) 1991-08-26
NO167737C true NO167737C (no) 1991-12-04

Family

ID=10633662

Family Applications (1)

Application Number Title Priority Date Filing Date
NO891176A NO167737C (no) 1988-03-18 1989-03-17 Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydroimidazo(1,4)benzodiazepin-2-oner.

Country Status (26)

Country Link
EP (1) EP0336466B1 (no)
JP (1) JP2693559B2 (no)
KR (1) KR0133073B1 (no)
CN (1) CN1031058C (no)
AT (1) ATE84035T1 (no)
AU (2) AU617435B2 (no)
BG (1) BG51251A3 (no)
CA (1) CA1310964C (no)
DE (1) DE68904102T2 (no)
DK (1) DK130989A (no)
ES (1) ES2053946T3 (no)
FI (1) FI89800C (no)
GB (1) GB8806449D0 (no)
GR (1) GR3006728T3 (no)
HU (2) HU203757B (no)
IE (1) IE63108B1 (no)
IL (1) IL89633A (no)
JO (1) JO1589B1 (no)
MY (1) MY104942A (no)
NO (1) NO167737C (no)
NZ (1) NZ228216A (no)
PH (1) PH27044A (no)
PT (1) PT90034B (no)
SU (1) SU1748647A3 (no)
TN (1) TNSN89039A1 (no)
ZA (1) ZA892062B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270464A (en) * 1989-03-14 1993-12-14 Janssen Pharmaceutica N.V. Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
NZ235137A (en) * 1989-09-13 1992-02-25 Janssen Pharmaceutica Nv Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
US5164376A (en) * 1989-10-30 1992-11-17 Hoffmann-Laroche Inc. Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
EP0436245A1 (en) * 1989-12-27 1991-07-10 Duphar International Research B.V Substituted 3,4-annelated benzimidazol-2(1H)-ones
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
NZ238664A (en) * 1990-07-06 1992-12-23 Janssen Pharmaceutica Nv Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
DE4036552C1 (no) * 1990-11-16 1992-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9109557D0 (en) 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
EP0639971B1 (en) * 1992-05-13 1999-09-22 The Wellcome Foundation Limited Therapeutic combinations
US20100234359A1 (en) 2007-08-20 2010-09-16 Evotec Neurosciences Gmbh Treatment of sleep disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534257A1 (fr) * 1982-10-12 1984-04-13 Roussel Uclaf Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
HU911782D0 (en) 1991-12-30
TNSN89039A1 (fr) 1991-02-04
FI891279A (fi) 1989-09-19
AU3131089A (en) 1989-09-21
CN1036957A (zh) 1989-11-08
JPH01275582A (ja) 1989-11-06
MY104942A (en) 1994-07-30
PT90034A (pt) 1989-11-10
DE68904102T2 (de) 1993-05-06
FI89800B (fi) 1993-08-13
JP2693559B2 (ja) 1997-12-24
NO167737B (no) 1991-08-26
DK130989D0 (da) 1989-03-17
ES2053946T3 (es) 1994-08-01
SU1748647A3 (ru) 1992-07-15
EP0336466A1 (en) 1989-10-11
BG51251A3 (en) 1993-03-15
HU206873B (en) 1993-01-28
HUT52099A (en) 1990-06-28
ATE84035T1 (de) 1993-01-15
JO1589B1 (en) 1989-12-16
AU617435B2 (en) 1991-11-28
KR890014546A (ko) 1989-10-24
AU8360291A (en) 1991-11-07
AU630575B2 (en) 1992-10-29
CA1310964C (en) 1992-12-01
PT90034B (pt) 1994-05-31
IE63108B1 (en) 1995-03-22
KR0133073B1 (en) 1998-04-17
DE68904102D1 (de) 1993-02-11
DK130989A (da) 1989-09-19
ZA892062B (en) 1990-11-28
GR3006728T3 (no) 1993-06-30
PH27044A (en) 1993-02-01
HU203757B (en) 1991-09-30
FI891279A0 (fi) 1989-03-17
GB8806449D0 (en) 1988-04-20
IL89633A0 (en) 1989-09-28
NO891176L (no) 1989-09-19
NO891176D0 (no) 1989-03-17
EP0336466B1 (en) 1992-12-30
CN1031058C (zh) 1996-02-21
FI89800C (fi) 1993-11-25
IE890851L (en) 1989-09-18
IL89633A (en) 1994-02-27
NZ228216A (en) 1991-01-29

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