ATE84035T1 - Antivirale tetrahydroimidazo(1,4)benzodiazepin-2- one. - Google Patents

Antivirale tetrahydroimidazo(1,4)benzodiazepin-2- one.

Info

Publication number
ATE84035T1
ATE84035T1 AT89200575T AT89200575T ATE84035T1 AT E84035 T1 ATE84035 T1 AT E84035T1 AT 89200575 T AT89200575 T AT 89200575T AT 89200575 T AT89200575 T AT 89200575T AT E84035 T1 ATE84035 T1 AT E84035T1
Authority
AT
Austria
Prior art keywords
6alkyl
hydrogen
6alkenyl
benzodiazepin
compounds
Prior art date
Application number
AT89200575T
Other languages
English (en)
Inventor
Alfons H M Raeymaekers
Gelder Josephus L H Van
Michael J Kukla
Henry J Breslin
Paul A J Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE84035T1 publication Critical patent/ATE84035T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT89200575T 1988-03-18 1989-03-08 Antivirale tetrahydroimidazo(1,4)benzodiazepin-2- one. ATE84035T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888806449A GB8806449D0 (en) 1988-03-18 1988-03-18 Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
EP89200575A EP0336466B1 (de) 1988-03-18 1989-03-08 Antivirale Tetrahydroimidazo(1,4)benzodiazepin-2-one

Publications (1)

Publication Number Publication Date
ATE84035T1 true ATE84035T1 (de) 1993-01-15

Family

ID=10633662

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89200575T ATE84035T1 (de) 1988-03-18 1989-03-08 Antivirale tetrahydroimidazo(1,4)benzodiazepin-2- one.

Country Status (26)

Country Link
EP (1) EP0336466B1 (de)
JP (1) JP2693559B2 (de)
KR (1) KR0133073B1 (de)
CN (1) CN1031058C (de)
AT (1) ATE84035T1 (de)
AU (2) AU617435B2 (de)
BG (1) BG51251A3 (de)
CA (1) CA1310964C (de)
DE (1) DE68904102T2 (de)
DK (1) DK130989A (de)
ES (1) ES2053946T3 (de)
FI (1) FI89800C (de)
GB (1) GB8806449D0 (de)
GR (1) GR3006728T3 (de)
HU (2) HU206873B (de)
IE (1) IE63108B1 (de)
IL (1) IL89633A (de)
JO (1) JO1589B1 (de)
MY (1) MY104942A (de)
NO (1) NO167737C (de)
NZ (1) NZ228216A (de)
PH (1) PH27044A (de)
PT (1) PT90034B (de)
SU (1) SU1748647A3 (de)
TN (1) TNSN89039A1 (de)
ZA (1) ZA892062B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270464A (en) * 1989-03-14 1993-12-14 Janssen Pharmaceutica N.V. Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
NZ235137A (en) * 1989-09-13 1992-02-25 Janssen Pharmaceutica Nv Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
US5164376A (en) * 1989-10-30 1992-11-17 Hoffmann-Laroche Inc. Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
EP0436245A1 (de) * 1989-12-27 1991-07-10 Duphar International Research B.V Substituierte 3,4-annelierte Benzimidazol-2(1H)-one
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
NZ238664A (en) * 1990-07-06 1992-12-23 Janssen Pharmaceutica Nv Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
DE4036552C1 (de) * 1990-11-16 1992-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9109557D0 (en) 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
DK0639971T3 (da) * 1992-05-13 2000-03-20 Wellcome Found Terapeutiske kombinationer
CA2696703C (en) 2007-08-20 2016-07-26 Evotec Neurosciences Gmbh Treatment of sleep disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534257A1 (fr) * 1982-10-12 1984-04-13 Roussel Uclaf Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
FI891279A (fi) 1989-09-19
AU8360291A (en) 1991-11-07
JPH01275582A (ja) 1989-11-06
TNSN89039A1 (fr) 1991-02-04
ES2053946T3 (es) 1994-08-01
SU1748647A3 (ru) 1992-07-15
DE68904102D1 (de) 1993-02-11
NO167737B (no) 1991-08-26
AU630575B2 (en) 1992-10-29
HU203757B (en) 1991-09-30
DK130989D0 (da) 1989-03-17
PT90034A (pt) 1989-11-10
FI89800B (fi) 1993-08-13
CN1036957A (zh) 1989-11-08
AU617435B2 (en) 1991-11-28
EP0336466B1 (de) 1992-12-30
JP2693559B2 (ja) 1997-12-24
KR0133073B1 (en) 1998-04-17
IE63108B1 (en) 1995-03-22
HU911782D0 (en) 1991-12-30
BG51251A3 (en) 1993-03-15
IL89633A0 (en) 1989-09-28
AU3131089A (en) 1989-09-21
FI89800C (fi) 1993-11-25
GB8806449D0 (en) 1988-04-20
NO891176L (no) 1989-09-19
JO1589B1 (en) 1989-12-16
NO891176D0 (no) 1989-03-17
HU206873B (en) 1993-01-28
CA1310964C (en) 1992-12-01
FI891279A0 (fi) 1989-03-17
PH27044A (en) 1993-02-01
MY104942A (en) 1994-07-30
KR890014546A (ko) 1989-10-24
EP0336466A1 (de) 1989-10-11
DK130989A (da) 1989-09-19
PT90034B (pt) 1994-05-31
IE890851L (en) 1989-09-18
NZ228216A (en) 1991-01-29
DE68904102T2 (de) 1993-05-06
HUT52099A (en) 1990-06-28
CN1031058C (zh) 1996-02-21
NO167737C (no) 1991-12-04
GR3006728T3 (de) 1993-06-30
ZA892062B (en) 1990-11-28
IL89633A (en) 1994-02-27

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