FI891279A0 - Antivirala tetrahydroimidazol /1,4/ benzodiazepin-2-oner. - Google Patents

Antivirala tetrahydroimidazol /1,4/ benzodiazepin-2-oner.

Info

Publication number
FI891279A0
FI891279A0 FI891279A FI891279A FI891279A0 FI 891279 A0 FI891279 A0 FI 891279A0 FI 891279 A FI891279 A FI 891279A FI 891279 A FI891279 A FI 891279A FI 891279 A0 FI891279 A0 FI 891279A0
Authority
FI
Finland
Prior art keywords
6alkyl
hydrogen
benzodiazepin
6alkenyl
tetrahydroimidazole
Prior art date
Application number
FI891279A
Other languages
English (en)
Other versions
FI89800C (fi
FI891279A (fi
FI89800B (fi
Inventor
Alfons Herman Marg Raeymaekers
Gelder Josephus Ludovicus Van
Michael Joseph Kukla
Henry Joseph Breslin
Paul Adriaan Jan Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI891279A0 publication Critical patent/FI891279A0/fi
Publication of FI891279A publication Critical patent/FI891279A/fi
Priority to FI930023A priority Critical patent/FI930023A/fi
Application granted granted Critical
Publication of FI89800B publication Critical patent/FI89800B/fi
Publication of FI89800C publication Critical patent/FI89800C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI891279A 1988-03-18 1989-03-17 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4,5,6,7-tetrahydroimidazo/4,5,1-jk//1,4/bensodiazepin-2-oner FI89800C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI930023A FI930023A (fi) 1988-03-18 1993-01-05 Mellanprodukter anvaendbara vid framstaellning av terapeutiskt vaerdefulla 4,5,6,7-tetrahydroimidazo(4,5,1-jk)(1,4)benzodiazepin-2-oner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8806449 1988-03-18
GB888806449A GB8806449D0 (en) 1988-03-18 1988-03-18 Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Publications (4)

Publication Number Publication Date
FI891279A0 true FI891279A0 (fi) 1989-03-17
FI891279A FI891279A (fi) 1989-09-19
FI89800B FI89800B (fi) 1993-08-13
FI89800C FI89800C (fi) 1993-11-25

Family

ID=10633662

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891279A FI89800C (fi) 1988-03-18 1989-03-17 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4,5,6,7-tetrahydroimidazo/4,5,1-jk//1,4/bensodiazepin-2-oner

Country Status (26)

Country Link
EP (1) EP0336466B1 (fi)
JP (1) JP2693559B2 (fi)
KR (1) KR0133073B1 (fi)
CN (1) CN1031058C (fi)
AT (1) ATE84035T1 (fi)
AU (2) AU617435B2 (fi)
BG (1) BG51251A3 (fi)
CA (1) CA1310964C (fi)
DE (1) DE68904102T2 (fi)
DK (1) DK130989A (fi)
ES (1) ES2053946T3 (fi)
FI (1) FI89800C (fi)
GB (1) GB8806449D0 (fi)
GR (1) GR3006728T3 (fi)
HU (2) HU203757B (fi)
IE (1) IE63108B1 (fi)
IL (1) IL89633A (fi)
JO (1) JO1589B1 (fi)
MY (1) MY104942A (fi)
NO (1) NO167737C (fi)
NZ (1) NZ228216A (fi)
PH (1) PH27044A (fi)
PT (1) PT90034B (fi)
SU (1) SU1748647A3 (fi)
TN (1) TNSN89039A1 (fi)
ZA (1) ZA892062B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270464A (en) * 1989-03-14 1993-12-14 Janssen Pharmaceutica N.V. Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
NZ235137A (en) * 1989-09-13 1992-02-25 Janssen Pharmaceutica Nv Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
US5164376A (en) * 1989-10-30 1992-11-17 Hoffmann-Laroche Inc. Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
EP0436245A1 (en) * 1989-12-27 1991-07-10 Duphar International Research B.V Substituted 3,4-annelated benzimidazol-2(1H)-ones
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
NZ238664A (en) * 1990-07-06 1992-12-23 Janssen Pharmaceutica Nv Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
DE4036552C1 (fi) * 1990-11-16 1992-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9109557D0 (en) 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
DK0639971T3 (da) * 1992-05-13 2000-03-20 Wellcome Found Terapeutiske kombinationer
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
EP2190435B1 (en) 2007-08-20 2018-05-30 Evotec International GmbH Treatment of sleep disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534257A1 (fr) * 1982-10-12 1984-04-13 Roussel Uclaf Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
AU630575B2 (en) 1992-10-29
KR890014546A (ko) 1989-10-24
DE68904102D1 (de) 1993-02-11
IE890851L (en) 1989-09-18
ES2053946T3 (es) 1994-08-01
CA1310964C (en) 1992-12-01
SU1748647A3 (ru) 1992-07-15
KR0133073B1 (en) 1998-04-17
CN1036957A (zh) 1989-11-08
HU911782D0 (en) 1991-12-30
IL89633A0 (en) 1989-09-28
EP0336466B1 (en) 1992-12-30
FI89800C (fi) 1993-11-25
DK130989D0 (da) 1989-03-17
HUT52099A (en) 1990-06-28
NO891176L (no) 1989-09-19
IE63108B1 (en) 1995-03-22
FI891279A (fi) 1989-09-19
DK130989A (da) 1989-09-19
BG51251A3 (en) 1993-03-15
ATE84035T1 (de) 1993-01-15
TNSN89039A1 (fr) 1991-02-04
JPH01275582A (ja) 1989-11-06
EP0336466A1 (en) 1989-10-11
PH27044A (en) 1993-02-01
HU206873B (en) 1993-01-28
IL89633A (en) 1994-02-27
NO167737C (no) 1991-12-04
JO1589B1 (en) 1989-12-16
AU8360291A (en) 1991-11-07
PT90034B (pt) 1994-05-31
NO167737B (no) 1991-08-26
MY104942A (en) 1994-07-30
NZ228216A (en) 1991-01-29
GR3006728T3 (fi) 1993-06-30
HU203757B (en) 1991-09-30
GB8806449D0 (en) 1988-04-20
ZA892062B (en) 1990-11-28
DE68904102T2 (de) 1993-05-06
JP2693559B2 (ja) 1997-12-24
FI89800B (fi) 1993-08-13
CN1031058C (zh) 1996-02-21
NO891176D0 (no) 1989-03-17
PT90034A (pt) 1989-11-10
AU3131089A (en) 1989-09-21
AU617435B2 (en) 1991-11-28

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: JANSSEN PHARMACEUTICA N.V.