BG40965A3 - Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines - Google Patents
Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidinesInfo
- Publication number
- BG40965A3 BG40965A3 BG8568329A BG6832985A BG40965A3 BG 40965 A3 BG40965 A3 BG 40965A3 BG 8568329 A BG8568329 A BG 8568329A BG 6832985 A BG6832985 A BG 6832985A BG 40965 A3 BG40965 A3 BG 40965A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- piperidines
- hetero
- methyl
- preparing
- bicyclic heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56936984A | 1984-01-09 | 1984-01-09 | |
US67113584A | 1984-11-13 | 1984-11-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
BG40965A3 true BG40965A3 (en) | 1987-03-14 |
Family
ID=27075046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG8568329A BG40965A3 (en) | 1984-01-09 | 1985-01-09 | Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0151826B1 (no) |
JP (1) | JPH0768240B2 (no) |
KR (2) | KR870001169B1 (no) |
AU (1) | AU573673B2 (no) |
BG (1) | BG40965A3 (no) |
CA (1) | CA1259609A (no) |
DE (1) | DE3486121T2 (no) |
DK (1) | DK8985A (no) |
ES (1) | ES8706668A1 (no) |
FI (1) | FI83867C (no) |
GR (1) | GR850060B (no) |
HU (1) | HU200338B (no) |
IE (1) | IE59707B1 (no) |
IL (1) | IL74018A (no) |
MA (1) | MA20323A1 (no) |
NO (1) | NO160849C (no) |
NZ (1) | NZ210776A (no) |
PH (1) | PH23995A (no) |
PT (1) | PT79809B (no) |
RO (1) | RO90622A (no) |
ZW (1) | ZW485A1 (no) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3484096D1 (de) * | 1983-11-30 | 1991-03-14 | Janssen Pharmaceutica Nv | Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine. |
US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
CA1260474A (en) * | 1984-12-03 | 1989-09-26 | Raymond A. Stokbroekx | Benzoxazol- and benzothiazolamine derivatives |
US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
FR2587029B1 (fr) * | 1985-09-11 | 1987-10-30 | Synthelabo | Derives de benzimidazole, leur preparation et leur application en therapeutique |
KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
ATE79620T1 (de) * | 1986-02-03 | 1992-09-15 | Janssen Pharmaceutica Nv | N-heterozyklische-4-piperidinamine enthaltende anti-histaminische zusammensetzungen. |
US4804658A (en) * | 1986-09-15 | 1989-02-14 | G. D. Searle & Co. | Imidazopyridine derivatives and pharmaceutical compositions |
US4943580A (en) * | 1987-03-09 | 1990-07-24 | Janssen Pharmaceutica N.V. | Anti-histaminic benzimidazole, imidazopyridine and purine derivatives |
NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
GB8716313D0 (en) * | 1987-07-10 | 1987-08-19 | Janssen Pharmaceutica Nv | 2-(heterocyclylalkyl)imidazopyridines |
US4908372A (en) * | 1988-10-13 | 1990-03-13 | Merrell Dow Pharmaceuticals Inc. | Antihistaminic piperidinyl benzimidazoles |
GB8900380D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
PH30434A (en) * | 1989-04-07 | 1997-05-09 | Janssen Pharmaceutica Nv | Hydroxyalkylfuranyl derivatives |
IT1229230B (it) * | 1989-05-08 | 1991-07-26 | Dompe Farmaceutici Spa | Piperidinilimidazopiridine farmacologicamente attive. |
JP2679745B2 (ja) * | 1989-06-29 | 1997-11-19 | 明治製菓株式会社 | アゾール誘導体及びそれらを有効成分とする抗潰瘍剤 |
US5200407A (en) * | 1989-06-29 | 1993-04-06 | Meiji Seika Kaburhiki Kaisha | Azole derivatives and anti-ulcerative composition containing same |
CA2022451C (en) * | 1989-08-03 | 2001-01-23 | Albert Anthony Carr | Anti-psychotic piperidynl benzimidazole compounds |
GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
KR100190299B1 (ko) * | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
US5217980A (en) * | 1990-07-19 | 1993-06-08 | Janssen Pharmaceutica N.V. | Oxazolyl and piperidinyl substituted benimidazolyl compounds |
WO1992006086A1 (en) * | 1990-10-01 | 1992-04-16 | Janssen Pharmaceutica N.V. | Novel 4-piperidinylcarbonyl derivatives |
EP0561973A1 (en) * | 1990-12-14 | 1993-09-29 | Merrell Dow Pharmaceuticals Inc. | Antiallergic compounds |
WO1993014083A1 (en) * | 1992-01-09 | 1993-07-22 | Janssen Pharmaceutica N.V. | Pharmaceutically active substituted benzimidazole derivatives |
ES2163407T3 (es) * | 1992-02-13 | 2002-02-01 | Merrell Pharma Inc | Derivados piperidinilos tiaciclicos. |
CA2091204C (en) * | 1992-03-11 | 1997-04-08 | Ronald J. Mattson | Antiischemic-piperazinyl and piperidinyl-cyclohexanes |
ES2048109B1 (es) * | 1992-07-20 | 1994-12-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. |
JPH08508030A (ja) * | 1993-03-18 | 1996-08-27 | メルク シヤープ エンド ドーム リミテツド | ベンゾイミダゾール誘導体 |
US5521183A (en) * | 1994-08-30 | 1996-05-28 | Allergan | Use of 5-HT ligands as anti-pruritic agents |
TW429256B (en) * | 1995-12-27 | 2001-04-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives |
KR20010032968A (ko) * | 1998-03-06 | 2001-04-25 | 디르크 반테 | 글리신 수송 저해제 |
EP1400519B1 (en) * | 1999-06-28 | 2007-03-07 | Janssen Pharmaceutica N.V. | Respiratory syncytial virus replication inhibitors |
KR100731276B1 (ko) * | 1999-06-28 | 2007-06-21 | 얀센 파마슈티카 엔.브이. | 호흡기 신시티움 바이러스 복제 억제제 |
US6747028B1 (en) | 1999-06-28 | 2004-06-08 | Hanssen Pharmaceutica, N.V. | Respiratory syncytial virus replication inhibitors |
TWI225488B (en) * | 1999-12-21 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivatives of homopiperidinyl substituted benzimidazole analogues |
AR033517A1 (es) | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
NZ528216A (en) * | 2001-02-24 | 2006-12-22 | Boehringer Ingelheim Pharma | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions |
US7030150B2 (en) | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
DK1404667T3 (da) | 2001-07-02 | 2006-07-10 | Astrazeneca Ab | Piperidinderivater, der er anvendelige som modulatorer af chemokinreceptoraktivitet |
US6530660B1 (en) | 2001-08-16 | 2003-03-11 | Contour Optik, Inc. | Eyeglass frame with a reversible arm |
GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
GB0122503D0 (en) | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
EP1465635A4 (en) * | 2002-01-10 | 2005-04-13 | Neurogen Corp | MELANIN-CONCENTRATING HORMONIC RECEPTOR LIGANDS: SUBSTITUTED 2- (4-BENZYL-PIPERAZIN-1-YLMETHYL) AND 2- (4-BENZYL-DIAZEPAN-1-YLMETHYL) -1H-BENZOIMIDAZOLE ANALOGUES |
SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
US6939877B2 (en) | 2002-09-12 | 2005-09-06 | Wyeth | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
WO2004069818A1 (en) * | 2003-01-17 | 2004-08-19 | Cv Therapeutics Inc. | Substituted heterocyclic compounds useful in the treatment of cardiovascular diseases |
SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
KR100640783B1 (ko) | 2004-10-30 | 2006-11-01 | 주식회사 하이닉스반도체 | 노이즈를 줄일 수 있는 데이터 출력 드라이버 |
WO2006094948A1 (en) | 2005-03-08 | 2006-09-14 | Janssen Pharmaceutica N.V. | Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists |
RU2008105987A (ru) | 2005-07-21 | 2009-08-27 | Астразенека Аб (Se) | Новые пиперидиновые производные |
ES2369320T3 (es) * | 2007-10-11 | 2011-11-29 | Glaxo Group Limited | Compuestos de ftalazina y pirido(3,4-d)piridazina como antagonistas del receptor h1. |
HUE028435T2 (en) | 2010-09-02 | 2016-12-28 | Suven Life Sciences Ltd | Heterocyclic compounds as histamine H3 receptor ligands |
US10913736B2 (en) * | 2014-08-22 | 2021-02-09 | University Of Washington | Specific inhibitors of methionyl-tRNA synthetase |
BR112017028448A2 (pt) | 2015-07-02 | 2018-08-28 | Horizon Orphan Llc | análogos de cisteamina resistentes a ado e usos dos mesmos |
WO2017207340A1 (de) * | 2016-05-31 | 2017-12-07 | Bayer Pharma Aktiengesellschaft | Neue substituierte benzimidazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2857391A (en) * | 1955-04-15 | 1958-10-21 | Merck & Co Inc | Aminomethylbenzimidazoles |
GB1260857A (en) * | 1968-07-10 | 1972-01-19 | Hexachimie | IMIDAZO-3H-(4,5-b)-PYRIDINE DERIVATIVES |
DE2334009A1 (de) * | 1973-07-04 | 1975-01-23 | Boehringer Mannheim Gmbh | Purin-derivate sowie verfahren zu ihrer herstellung |
SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
US4342870A (en) * | 1980-03-28 | 1982-08-03 | Janssen Pharmaceutica N.V. | Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives |
PL129612B1 (en) * | 1980-07-24 | 1984-05-31 | Rhone Poulenc Ind | Process for preparing novel derivatives of 2,3,6,7-tetrahydrothiazole/3,2-a/pirymidin-5-one |
US4443451A (en) * | 1981-07-15 | 1984-04-17 | Janssen Pharmaceutica N.V. | Bicyclic pyrimidin-5-one derivatives |
US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
DE3484096D1 (de) * | 1983-11-30 | 1991-03-14 | Janssen Pharmaceutica Nv | Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine. |
US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
-
1984
- 1984-11-16 PH PH31450A patent/PH23995A/en unknown
- 1984-12-13 KR KR1019840007901A patent/KR870001169B1/ko not_active IP Right Cessation
- 1984-12-13 DE DE8484201851T patent/DE3486121T2/de not_active Expired - Fee Related
- 1984-12-13 EP EP84201851A patent/EP0151826B1/en not_active Expired - Lifetime
- 1984-12-31 ES ES539281A patent/ES8706668A1/es not_active Expired
-
1985
- 1985-01-07 CA CA000471589A patent/CA1259609A/en not_active Expired
- 1985-01-07 AU AU37364/85A patent/AU573673B2/en not_active Ceased
- 1985-01-07 NZ NZ210776A patent/NZ210776A/en unknown
- 1985-01-08 DK DK8985A patent/DK8985A/da not_active Application Discontinuation
- 1985-01-08 NO NO850085A patent/NO160849C/no unknown
- 1985-01-08 JP JP60000479A patent/JPH0768240B2/ja not_active Expired - Lifetime
- 1985-01-08 IL IL74018A patent/IL74018A/xx unknown
- 1985-01-08 ZW ZW4/85A patent/ZW485A1/xx unknown
- 1985-01-08 FI FI850079A patent/FI83867C/fi not_active IP Right Cessation
- 1985-01-08 HU HU8561A patent/HU200338B/hu not_active IP Right Cessation
- 1985-01-08 IE IE4285A patent/IE59707B1/en not_active IP Right Cessation
- 1985-01-08 RO RO85117252A patent/RO90622A/ro unknown
- 1985-01-08 MA MA20547A patent/MA20323A1/fr unknown
- 1985-01-08 PT PT79809A patent/PT79809B/pt not_active IP Right Cessation
- 1985-01-09 BG BG8568329A patent/BG40965A3/xx unknown
- 1985-01-09 GR GR850060A patent/GR850060B/el unknown
-
1987
- 1987-08-13 KR KR1019870008895A patent/KR900001545B1/ko not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BG40965A3 (en) | Method for preparing 4- [(bicyclic heterocyclic)- methyl and -hetero]- piperidines | |
PT81000A (en) | Process for the preparation of heterocyclic derivatives | |
YU44632B (en) | Process for obtaining new 2-(n-substituted-guanidine)-4-heteroarylthiazole | |
PL265151A1 (en) | Method for manufacturing new heterocyclic carboxyamides | |
BG45698A3 (en) | Method for preparing of dimethyltherephthalate | |
PL279345A1 (en) | Method for manufacturing new heterocyclic compounds | |
PL252743A1 (en) | Method of obtaining heterocyclic compounds | |
GR82451B (en) | Method of preparing heterocyclic compounds | |
PT81510B (en) | Process for preparing v1-vasopressin antagonists | |
BG44203A3 (en) | Method for preparing of 2- oxyindol- 1- carboxamides | |
HU9201172D0 (en) | Method for producing 5-substituted hydantoin derivatives | |
GR860718B (en) | Method for the preparation of heterocyclic compounds | |
PT80327B (en) | Process for preparing 3-substituted thiopyrones | |
GR861806B (en) | Method for the preparation of heterocyclic compounds | |
GR861906B (en) | Method for preparing heterocyclic compounds | |
BG39193A1 (en) | Method for preparing 2- [(n- 2- pyridylcarbamoyl)- methyl]- saccharin | |
BG38699A1 (en) | Method for preparing triacetonamine | |
PL245781A1 (en) | Method of obtaining novel heterocyclic compounds | |
PL255306A1 (en) | Method of obtaining novel heterocyclic compounds | |
PL251480A1 (en) | Method of obtaining novel heterocyclic compounds | |
BG42834A3 (en) | Method for preparing azole compounds | |
GR860095B (en) | Method for the preparation of novel heterocyclic compounds | |
GR80572B (en) | Method for the preparation of heterocyclic compounds | |
GR860039B (en) | Method for the preparation of heterocyclic compounds | |
BG38361A1 (en) | Method for preparing substituted aminonitrobenzenes |