BG106822A - Близко инфрачервено флуоресцентно контрастно средство и флуоресцентно изобразяване - Google Patents
Близко инфрачервено флуоресцентно контрастно средство и флуоресцентно изобразяване Download PDFInfo
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- BG106822A BG106822A BG106822A BG10682202A BG106822A BG 106822 A BG106822 A BG 106822A BG 106822 A BG106822 A BG 106822A BG 10682202 A BG10682202 A BG 10682202A BG 106822 A BG106822 A BG 106822A
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- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 235000013557 nattō Nutrition 0.000 description 1
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000269 nucleophilic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- MHYFEEDKONKGEB-UHFFFAOYSA-N oxathiane 2,2-dioxide Chemical compound O=S1(=O)CCCCO1 MHYFEEDKONKGEB-UHFFFAOYSA-N 0.000 description 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 208000007578 phototoxic dermatitis Diseases 0.000 description 1
- 231100000018 phototoxicity Toxicity 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- 235000011056 potassium acetate Nutrition 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002207 retinal effect Effects 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical compound FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 description 1
- 229960002078 sevoflurane Drugs 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 125000004436 sodium atom Chemical group 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 125000000547 substituted alkyl group Chemical group 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 125000001174 sulfone group Chemical group 0.000 description 1
- 125000004963 sulfonylalkyl group Chemical group 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- IMFACGCPASFAPR-UHFFFAOYSA-N tributylamine Chemical class CCCCN(CCCC)CCCC IMFACGCPASFAPR-UHFFFAOYSA-N 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1999/009959 WO2001043781A1 (en) | 1999-12-15 | 1999-12-15 | Near infrared fluorescent contrast agent and fluorescence imaging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG106822A true BG106822A (bg) | 2003-01-31 |
Family
ID=8167530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG106822A BG106822A (bg) | 1999-12-15 | 2002-06-13 | Близко инфрачервено флуоресцентно контрастно средство и флуоресцентно изобразяване |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1237583A1 (tr) |
| JP (1) | JP2003517025A (tr) |
| KR (1) | KR20020082207A (tr) |
| CN (1) | CN1217701C (tr) |
| AU (1) | AU2097500A (tr) |
| BG (1) | BG106822A (tr) |
| BR (1) | BR9917587A (tr) |
| CA (1) | CA2394539C (tr) |
| EA (1) | EA200200635A1 (tr) |
| EE (1) | EE200200321A (tr) |
| HU (1) | HUP0204024A2 (tr) |
| IL (1) | IL149798A0 (tr) |
| MX (1) | MXPA02005806A (tr) |
| NO (1) | NO328630B1 (tr) |
| PL (1) | PL355891A1 (tr) |
| SK (1) | SK8142002A3 (tr) |
| TR (1) | TR200201567T2 (tr) |
| WO (1) | WO2001043781A1 (tr) |
| YU (1) | YU44402A (tr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7682602B2 (en) * | 2003-12-19 | 2010-03-23 | Konica Minolta Medical & Graphic, Inc. | Near-infrared fluorescent contrast medium |
| JP2005220045A (ja) * | 2004-02-04 | 2005-08-18 | Konica Minolta Medical & Graphic Inc | 蛍光造影剤 |
| JP5074044B2 (ja) | 2007-01-18 | 2012-11-14 | オリンパス株式会社 | 蛍光観察装置および蛍光観察装置の作動方法 |
| US8344158B2 (en) * | 2007-08-15 | 2013-01-01 | Washington University | Fluorescent polymethine cyanine dyes |
| US20090214436A1 (en) | 2008-02-18 | 2009-08-27 | Washington University | Dichromic fluorescent compounds |
| JP2011046663A (ja) | 2009-08-28 | 2011-03-10 | Fujifilm Corp | 近赤外蛍光造影剤 |
| US8401618B2 (en) | 2009-08-28 | 2013-03-19 | Visen Medical, Inc. | Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique |
| WO2011038006A1 (en) | 2009-09-22 | 2011-03-31 | Visen Medical, Inc. | Systems and methods for virtual index-matching of diffusive media |
| EP2523596A4 (en) * | 2010-01-14 | 2015-02-25 | Univ California | DEVICES, SYSTEMS AND METHODS FOR DETECTING AND REDUCING OR PREVENTING THE ENTRY OF INFLAMMATORY MEDIATORS IN LACTIFIED CONDUITS |
| GB201010878D0 (en) | 2010-06-29 | 2010-08-11 | Ge Healthcare As | Dye compositiion and dye syntheses |
| EP2806781B1 (en) | 2012-01-23 | 2018-03-21 | Washington University | Goggle imaging systems and methods |
| US10743768B2 (en) | 2012-10-15 | 2020-08-18 | Visen Medical, Inc. | Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources |
| US20170232119A1 (en) | 2013-03-15 | 2017-08-17 | Purdue Research Foundation | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors |
| JP6192799B2 (ja) | 2013-03-15 | 2017-09-06 | パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | 腫瘍の標的画像化に使用される化合物にコンジュゲートしているアミノ酸連結基の合成および組成物 |
| US10986997B2 (en) | 2013-12-31 | 2021-04-27 | Memorial Sloan Kettering Cancer Center | Systems, methods, and apparatus for multichannel imaging of fluorescent sources in real time |
| KR20170094268A (ko) | 2014-12-15 | 2017-08-17 | 메모리얼 슬로안-케터링 캔서 센터 | 향상된 신경-결합 선택성을 갖는 고리형 펩티드, 상기 고리형 펩티드와 결합된 나노입자, 및 실시간 생체내 신경 조직 영상화를 위한 이들의 용도 |
| US10806804B2 (en) | 2015-05-06 | 2020-10-20 | Washington University | Compounds having RD targeting motifs and methods of use thereof |
| TR201810532T4 (tr) * | 2015-06-03 | 2018-08-27 | Surgimab S A S | Floresan konjügatlar. |
| CN105222828B (zh) * | 2015-09-30 | 2017-05-24 | 东南大学 | 一种贴壁射流速度场和浓度场的同步测量装置与方法 |
| WO2017106525A1 (en) | 2015-12-15 | 2017-06-22 | Memorial Sloan Kettering Cancer Center | Imaging systems and methods for tissue differentiation, e.g., for intraoperative visualization |
| AU2017368005A1 (en) | 2016-11-30 | 2019-06-20 | Cornell University | Inhibitor-functionalized ultrasmall nanoparticles and methods thereof |
| US11989803B2 (en) | 2018-03-30 | 2024-05-21 | Perkinelmer Health Sciences, Inc. | Systems and methods for 3D reconstruction of anatomical organs and inclusions using short-wave infrared (SWIR) projection tomography |
| US11712482B2 (en) | 2019-12-13 | 2023-08-01 | Washington University | Near infrared fluorescent dyes, formulations and related methods |
| US11964965B2 (en) * | 2020-05-08 | 2024-04-23 | On Target Laboratories, LLC | Methods of manufacture and synthesis of fluorescent dye compounds and uses thereof |
| EP4015004A1 (en) | 2020-12-18 | 2022-06-22 | Phi Pharma SA | Proteoglycan specific branched peptides |
| CN114459862A (zh) * | 2022-01-13 | 2022-05-10 | 华腾实业（深圳）股份有限公司 | 一种高识别的真菌荧光染色液 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2163393T3 (es) * | 1990-05-15 | 2002-02-01 | Hyperion Inc | Porfirina fluorescente y ftalocianina fluorescente - derivados de polietilenglicol, poliol y sacaridos como sondas fluorescentes. |
| CN1093768C (zh) * | 1995-01-30 | 2002-11-06 | 第一化学药品株式会社 | 诊断用标记物 |
| JP2000095758A (ja) * | 1998-09-18 | 2000-04-04 | Schering Ag | 近赤外蛍光造影剤および蛍光造影方法 |
-
1999
- 1999-12-15 TR TR2002/01567T patent/TR200201567T2/tr unknown
- 1999-12-15 WO PCT/EP1999/009959 patent/WO2001043781A1/en not_active Application Discontinuation
- 1999-12-15 HU HU0204024A patent/HUP0204024A2/hu unknown
- 1999-12-15 EP EP99965468A patent/EP1237583A1/en not_active Withdrawn
- 1999-12-15 AU AU20975/00A patent/AU2097500A/en not_active Abandoned
- 1999-12-15 BR BR9917587-8A patent/BR9917587A/pt not_active Application Discontinuation
- 1999-12-15 JP JP2001544917A patent/JP2003517025A/ja active Pending
- 1999-12-15 YU YU44402A patent/YU44402A/sh unknown
- 1999-12-15 MX MXPA02005806A patent/MXPA02005806A/es unknown
- 1999-12-15 IL IL14979899A patent/IL149798A0/xx not_active IP Right Cessation
- 1999-12-15 EA EA200200635A patent/EA200200635A1/ru unknown
- 1999-12-15 SK SK814-2002A patent/SK8142002A3/sk unknown
- 1999-12-15 EE EEP200200321A patent/EE200200321A/xx unknown
- 1999-12-15 CA CA002394539A patent/CA2394539C/en not_active Expired - Fee Related
- 1999-12-15 KR KR1020027007635A patent/KR20020082207A/ko not_active Application Discontinuation
- 1999-12-15 PL PL99355891A patent/PL355891A1/xx not_active Application Discontinuation
- 1999-12-15 CN CN998170437A patent/CN1217701C/zh not_active Expired - Fee Related
-
2002
- 2002-06-13 BG BG106822A patent/BG106822A/bg unknown
- 2002-06-14 NO NO20022837A patent/NO328630B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EE200200321A (et) | 2003-10-15 |
| TR200201567T2 (tr) | 2002-11-21 |
| MXPA02005806A (es) | 2010-10-26 |
| NO20022837L (no) | 2002-06-14 |
| JP2003517025A (ja) | 2003-05-20 |
| CN1384760A (zh) | 2002-12-11 |
| NO328630B1 (no) | 2010-04-12 |
| KR20020082207A (ko) | 2002-10-30 |
| YU44402A (sh) | 2005-03-15 |
| CN1217701C (zh) | 2005-09-07 |
| SK8142002A3 (en) | 2002-12-03 |
| CA2394539C (en) | 2009-10-27 |
| EA200200635A1 (ru) | 2002-12-26 |
| AU2097500A (en) | 2001-06-25 |
| IL149798A0 (en) | 2002-11-10 |
| PL355891A1 (en) | 2004-05-31 |
| BR9917587A (pt) | 2002-08-06 |
| EP1237583A1 (en) | 2002-09-11 |
| HUP0204024A2 (en) | 2003-04-28 |
| WO2001043781A1 (en) | 2001-06-21 |
| CA2394539A1 (en) | 2001-06-21 |
| NO20022837D0 (no) | 2002-06-14 |
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