HUP0204024A2 - Near infrared fluorescent contrast agent and fluorescence imaging - Google Patents

Near infrared fluorescent contrast agent and fluorescence imaging

Info

Publication number
HUP0204024A2
HUP0204024A2 HU0204024A HUP0204024A HUP0204024A2 HU P0204024 A2 HUP0204024 A2 HU P0204024A2 HU 0204024 A HU0204024 A HU 0204024A HU P0204024 A HUP0204024 A HU P0204024A HU P0204024 A2 HUP0204024 A2 HU P0204024A2
Authority
HU
Hungary
Prior art keywords
contrast agent
near infrared
fluorescence imaging
infrared fluorescent
fluorescent contrast
Prior art date
Application number
HU0204024A
Other languages
Hungarian (hu)
Inventor
Hiroaki Eguchi
Toru Harada
Michihito Inagaki
Yoshio Inagaki
Naoto Miwa
Masafumi Okumura
Original Assignee
Fuji Photo Film Co Ltd
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Photo Film Co Ltd, Schering Ag filed Critical Fuji Photo Film Co Ltd
Publication of HUP0204024A2 publication Critical patent/HUP0204024A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes

Abstract

A találmány tárgya a közeli infravörösben fluoreszkáló kontrasztanyagés fluoreszcens leképezés az említett kontrasztanyag segítségével. Atalálmány tárgyát képező kontrasztanyag alacsony toxicitással éskiváló vízoldhatósággal rendelkezik, és fluoreszcenciát bocsát ki aközeli infravörös tartományban, amely képes áthatolni az élőszöveteken, és lehetővé teszi a tumor és/vagy véredény-specifikusleképezését. ÓThe subject of the invention is fluorescence imaging of a contrast material that fluoresces in the near infrared using said contrast material. The contrast agent of the invention has low toxicity and excellent water solubility, and emits fluorescence in the near-infrared range, which can penetrate living tissues and enable tumor and/or vessel-specific imaging. HE

HU0204024A 1999-12-15 1999-12-15 Near infrared fluorescent contrast agent and fluorescence imaging HUP0204024A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1999/009959 WO2001043781A1 (en) 1999-12-15 1999-12-15 Near infrared fluorescent contrast agent and fluorescence imaging

Publications (1)

Publication Number Publication Date
HUP0204024A2 true HUP0204024A2 (en) 2003-04-28

Family

ID=8167530

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0204024A HUP0204024A2 (en) 1999-12-15 1999-12-15 Near infrared fluorescent contrast agent and fluorescence imaging

Country Status (19)

Country Link
EP (1) EP1237583A1 (en)
JP (1) JP2003517025A (en)
KR (1) KR20020082207A (en)
CN (1) CN1217701C (en)
AU (1) AU2097500A (en)
BG (1) BG106822A (en)
BR (1) BR9917587A (en)
CA (1) CA2394539C (en)
EA (1) EA200200635A1 (en)
EE (1) EE200200321A (en)
HU (1) HUP0204024A2 (en)
IL (1) IL149798A0 (en)
MX (1) MXPA02005806A (en)
NO (1) NO328630B1 (en)
PL (1) PL355891A1 (en)
SK (1) SK8142002A3 (en)
TR (1) TR200201567T2 (en)
WO (1) WO2001043781A1 (en)
YU (1) YU44402A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7682602B2 (en) * 2003-12-19 2010-03-23 Konica Minolta Medical & Graphic, Inc. Near-infrared fluorescent contrast medium
JP2005220045A (en) * 2004-02-04 2005-08-18 Konica Minolta Medical & Graphic Inc Fluorescent contrast agent
JP5074044B2 (en) * 2007-01-18 2012-11-14 オリンパス株式会社 Fluorescence observation apparatus and method of operating fluorescence observation apparatus
US8344158B2 (en) * 2007-08-15 2013-01-01 Washington University Fluorescent polymethine cyanine dyes
US20090214436A1 (en) 2008-02-18 2009-08-27 Washington University Dichromic fluorescent compounds
JP2011046663A (en) 2009-08-28 2011-03-10 Fujifilm Corp Near infrared fluorescent imaging agent
AU2010286592B2 (en) 2009-08-28 2015-08-13 Visen Medical, Inc. Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique
JP5945226B2 (en) 2009-09-22 2016-07-05 ビセン メディカル， インコーポレイテッド System and method for virtual refractive index matching of diffusing media
CN102711595A (en) * 2010-01-14 2012-10-03 加利福尼亚大学董事会 Devices, systems and methods to detect and reduce or prevent entry of inflammatory mediators into milk ducts
GB201010878D0 (en) 2010-06-29 2010-08-11 Ge Healthcare As Dye compositiion and dye syntheses
EP2806781B1 (en) 2012-01-23 2018-03-21 Washington University Goggle imaging systems and methods
US10743768B2 (en) 2012-10-15 2020-08-18 Visen Medical, Inc. Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources
US9333270B2 (en) 2013-03-15 2016-05-10 Purdue Research Foundation Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors
AU2014373656B2 (en) 2013-12-31 2019-12-05 Cornell University Systems, methods, and apparatus for multichannel imaging of fluorescent sources in real time
JP6751715B2 (en) 2014-12-15 2020-09-09 メモリアル スローン ケタリング キャンサー センター Cyclic peptide with enhanced neural binding selectivity, nanoparticles bound to the cyclic peptide, and use of the cyclic peptide for real-time in vivo neural tissue imaging.
US10806804B2 (en) 2015-05-06 2020-10-20 Washington University Compounds having RD targeting motifs and methods of use thereof
KR20180014027A (en) * 2015-06-03 2018-02-07 서지마브 에스.에이.에스. Fluorescent conjugate
CN105222828B (en) * 2015-09-30 2017-05-24 东南大学 Synchronization measurement device for wall-adherent jet speed field and concentration field and method
JP2019509252A (en) 2015-12-15 2019-04-04 メモリアル スローン ケタリング キャンサー センター Imaging systems and methods for tissue differentiation, eg, visualization during surgery
CN110167601A (en) 2016-11-30 2019-08-23 纪念斯隆凯特琳癌症中心 Inhibitor-small nanoparticle of functionalization ultra micro and its method
EP4072598A4 (en) 2019-12-13 2024-02-21 Washington University St Louis Near infrared fluorescent dyes, formulations and related methods
EP4015004A1 (en) 2020-12-18 2022-06-22 Phi Pharma SA Proteoglycan specific branched peptides
CN114459862A (en) * 2022-01-13 2022-05-10 华腾实业（深圳）股份有限公司 High-identification fungus fluorescent staining solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018006A1 (en) * 1990-05-15 1991-11-28 Diatron Corporation Fluorescent porphyrin, and fluorescent phthalocyanine - polyethylene glycol, polyol, and saccharide derivatives as fluorescent probes
ATE264694T1 (en) * 1995-01-30 2004-05-15 Daiichi Pure Chemicals Co Ltd DIAGNOSTIC MARKER
JP2000095758A (en) * 1998-09-18 2000-04-04 Schering Ag Near-infrared, fluorescent contrast medium, and its production

Also Published As

Publication number Publication date
KR20020082207A (en) 2002-10-30
CN1384760A (en) 2002-12-11
EA200200635A1 (en) 2002-12-26
CA2394539A1 (en) 2001-06-21
WO2001043781A1 (en) 2001-06-21
YU44402A (en) 2005-03-15
EE200200321A (en) 2003-10-15
SK8142002A3 (en) 2002-12-03
IL149798A0 (en) 2002-11-10
CA2394539C (en) 2009-10-27
TR200201567T2 (en) 2002-11-21
NO20022837L (en) 2002-06-14
BG106822A (en) 2003-01-31
NO328630B1 (en) 2010-04-12
EP1237583A1 (en) 2002-09-11
CN1217701C (en) 2005-09-07
AU2097500A (en) 2001-06-25
BR9917587A (en) 2002-08-06
PL355891A1 (en) 2004-05-31
JP2003517025A (en) 2003-05-20
NO20022837D0 (en) 2002-06-14
MXPA02005806A (en) 2010-10-26

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