BE863883A - Procede de preparation de derives de la pyrrolidine - Google Patents
Procede de preparation de derives de la pyrrolidineInfo
- Publication number
- BE863883A BE863883A BE185100A BE185100A BE863883A BE 863883 A BE863883 A BE 863883A BE 185100 A BE185100 A BE 185100A BE 185100 A BE185100 A BE 185100A BE 863883 A BE863883 A BE 863883A
- Authority
- BE
- Belgium
- Prior art keywords
- pyrrolidine derivatives
- preparing pyrrolidine
- preparing
- derivatives
- pyrrolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B43—WRITING OR DRAWING IMPLEMENTS; BUREAU ACCESSORIES
- B43K—IMPLEMENTS FOR WRITING OR DRAWING
- B43K24/00—Mechanisms for selecting, projecting, retracting or locking writing units
- B43K24/02—Mechanisms for selecting, projecting, retracting or locking writing units for locking a single writing unit in only fully projected or retracted positions
- B43K24/08—Mechanisms for selecting, projecting, retracting or locking writing units for locking a single writing unit in only fully projected or retracted positions operated by push-buttons
- B43K24/084—Mechanisms for selecting, projecting, retracting or locking writing units for locking a single writing unit in only fully projected or retracted positions operated by push-buttons with saw-like or analogous cams
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J115/00—Adhesives based on rubber derivatives
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20227/77A IT1075280B (it) | 1977-02-11 | 1977-02-11 | Procedimento per la preparazione di derivati pirrolidinici |
Publications (1)
Publication Number | Publication Date |
---|---|
BE863883A true BE863883A (fr) | 1978-08-10 |
Family
ID=11164931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE185100A BE863883A (fr) | 1977-02-11 | 1978-02-10 | Procede de preparation de derives de la pyrrolidine |
Country Status (26)
Country | Link |
---|---|
US (1) | US4173569A (xx) |
JP (1) | JPS53101367A (xx) |
AR (1) | AR223958A1 (xx) |
AT (1) | AT362782B (xx) |
AU (1) | AU513992B2 (xx) |
BE (1) | BE863883A (xx) |
CA (1) | CA1087200A (xx) |
CH (1) | CH637928A5 (xx) |
CS (1) | CS214800B2 (xx) |
DE (2) | DE2758939A1 (xx) |
DK (1) | DK155733C (xx) |
ES (1) | ES466856A1 (xx) |
FI (1) | FI67695C (xx) |
FR (1) | FR2380257A1 (xx) |
GB (1) | GB1588075A (xx) |
HU (1) | HU178587B (xx) |
IN (1) | IN148327B (xx) |
IT (1) | IT1075280B (xx) |
MX (1) | MX5950E (xx) |
NL (1) | NL190412C (xx) |
NO (1) | NO148148C (xx) |
NZ (1) | NZ186431A (xx) |
PL (1) | PL112858B1 (xx) |
PT (1) | PT67642A (xx) |
SU (1) | SU755195A3 (xx) |
YU (1) | YU40321B (xx) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1141287B (it) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono |
FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
IT1206699B (it) * | 1984-02-27 | 1989-04-27 | Isf Spa | Procedimento per preparare derivati di pirrolidone. |
IT1173768B (it) * | 1984-04-02 | 1987-06-24 | Isf Spa | Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti |
CH666483A5 (de) * | 1985-01-16 | 1988-07-29 | Lonza Ag | Verfahren zur herstellung von thiotetronsaeure. |
EP0223328B1 (en) | 1985-07-26 | 1992-01-29 | Denki Kagaku Kogyo Kabushiki Kaisha | Process for producing oxiracetam |
CH668423A5 (de) * | 1986-06-19 | 1988-12-30 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen. |
HU195773B (en) * | 1985-09-24 | 1988-07-28 | Lonza Ag | Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid |
IL80071A0 (en) * | 1985-09-24 | 1986-12-31 | Lonza Ag | Pyrrolidine acetamide derivatives |
CH666891A5 (de) * | 1985-11-26 | 1988-08-31 | Lonza Ag | 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung. |
CH668424A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung. |
CH668422A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure. |
CH667655A5 (de) * | 1986-09-24 | 1988-10-31 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen. |
CH670644A5 (xx) * | 1986-12-18 | 1989-06-30 | Lonza Ag | |
IT1215581B (it) * | 1987-06-25 | 1990-02-14 | Roussel Maestretti Spa | Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali. |
DE3813416A1 (de) * | 1988-04-21 | 1989-11-02 | Hoechst Ag | 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte |
DE58909320D1 (de) * | 1988-09-06 | 1995-08-03 | Lonza Ag | Verfahren zur Herstellung von 5-Alkyltetramsäuren. |
FI95034C (fi) * | 1989-03-15 | 1995-12-11 | Lonza Ag | Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi |
CH680293A5 (xx) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
GB9121289D0 (en) * | 1991-10-08 | 1991-11-20 | Isf Spa | Composition and use |
JP2969616B2 (ja) * | 1994-11-24 | 1999-11-02 | 田辺製薬株式会社 | 4−メルカプトピロリジン化合物の製法 |
EP0951468A4 (en) * | 1996-11-22 | 2001-06-06 | Mona Industries Inc | SILICONE MONOMERS AND OLIGOMERS CONTAINING A CARBOXYL FUNCTIONAL GROUP |
US5679798A (en) * | 1996-11-22 | 1997-10-21 | Mona Industries, Inc. | Silicone monomers having a carboxyl functional group thereon |
KR100424393B1 (ko) * | 2001-11-26 | 2004-03-24 | 한국화학연구원 | 옥시라세탐의 제조방법 |
JP4378326B2 (ja) * | 2005-07-26 | 2009-12-02 | キヤノン株式会社 | 駆動装置及び光量調節装置 |
DK3260118T3 (da) * | 2008-10-16 | 2021-04-19 | Univ Johns Hopkins | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
CN101747259B (zh) * | 2008-12-18 | 2012-02-15 | 北京大学 | 氮杂糖类化合物及其合成方法及应用 |
CN101575309B (zh) * | 2009-04-28 | 2011-05-18 | 中国医药集团总公司四川抗菌素工业研究所 | 合成(s)-奥拉西坦的方法 |
CN101704778B (zh) * | 2009-09-30 | 2012-10-17 | 厦门市华兴化工有限公司 | 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法 |
EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
DK2968220T3 (da) | 2013-03-15 | 2021-06-14 | Agenebio Inc | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
EP3827820A1 (en) | 2013-03-15 | 2021-06-02 | The Johns Hopkins University | Brivaracetam for improving cognitive function |
CN104513189B (zh) * | 2014-12-19 | 2017-07-28 | 深圳市海滨制药有限公司 | 一种奥拉西坦中间体及其制备方法和应用 |
CN106166150A (zh) * | 2015-05-18 | 2016-11-30 | 重庆润泽医药有限公司 | 右旋奥拉西坦在制药领域中的应用 |
CN107810002B (zh) | 2015-05-22 | 2021-01-05 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
JP2019531323A (ja) * | 2016-10-24 | 2019-10-31 | チョンキン ランゼ ファーマスーティカル カンパニー リミテッド | (r)−4−ヒドロキシ−2−オキソ−1−ピロリジンアセトアミドの結晶型、調製方法、用途 |
JP2019531314A (ja) | 2016-10-24 | 2019-10-31 | チョンキン ランゼ ファーマスーティカル カンパニー リミテッド | 右旋性オキシラセタムの新しい結晶型、調製方法、用途 |
JP6957807B2 (ja) * | 2016-10-24 | 2021-11-02 | チョンキン ランゼ ファーマスーティカル カンパニー リミテッド | 右旋性オキシラセタムの2型結晶、調製方法および用途 |
CN108299267A (zh) | 2017-01-12 | 2018-07-20 | 重庆润泽医药有限公司 | (r)-4-羟基-2-氧-1-吡咯烷乙酰胺的晶型及其制备方法和用途 |
CN114621128A (zh) * | 2022-03-10 | 2022-06-14 | 成都百途医药科技有限公司 | 一种(s)-奥拉西坦的制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR211398Q (es) | 1975-08-13 | 1977-12-15 | Isf Spa | Un procedimiento para preparar derivados de ( -pirrolin -2- on -1- il)-acilamida |
IT1045043B (it) | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
-
1977
- 1977-02-11 IT IT20227/77A patent/IT1075280B/it active Protection Beyond IP Right Term
- 1977-12-30 DE DE19772758939 patent/DE2758939A1/de not_active Withdrawn
- 1977-12-30 DE DE19772758937 patent/DE2758937A1/de active Granted
-
1978
- 1978-02-08 GB GB5046/78A patent/GB1588075A/en not_active Expired
- 1978-02-08 FI FI780407A patent/FI67695C/fi not_active IP Right Cessation
- 1978-02-08 AU AU33091/78A patent/AU513992B2/en not_active Expired
- 1978-02-08 AT AT0088878A patent/AT362782B/de not_active IP Right Cessation
- 1978-02-08 CS CS78816A patent/CS214800B2/cs unknown
- 1978-02-08 AR AR271030A patent/AR223958A1/es active
- 1978-02-08 US US05/876,169 patent/US4173569A/en not_active Expired - Lifetime
- 1978-02-08 IN IN104/DEL/78A patent/IN148327B/en unknown
- 1978-02-09 NL NLAANVRAGE7801500,A patent/NL190412C/xx not_active IP Right Cessation
- 1978-02-09 MX MX786832U patent/MX5950E/es unknown
- 1978-02-09 CH CH145778A patent/CH637928A5/de not_active IP Right Cessation
- 1978-02-09 CA CA296,540A patent/CA1087200A/en not_active Expired
- 1978-02-09 HU HU78IE824A patent/HU178587B/hu not_active IP Right Cessation
- 1978-02-09 YU YU302/78A patent/YU40321B/xx unknown
- 1978-02-09 PT PT67642A patent/PT67642A/pt unknown
- 1978-02-09 NZ NZ186431A patent/NZ186431A/xx unknown
- 1978-02-10 DK DK063178A patent/DK155733C/da not_active IP Right Cessation
- 1978-02-10 ES ES466856A patent/ES466856A1/es not_active Expired
- 1978-02-10 SU SU782577623A patent/SU755195A3/ru active
- 1978-02-10 JP JP1484478A patent/JPS53101367A/ja active Granted
- 1978-02-10 PL PL1978204549A patent/PL112858B1/pl unknown
- 1978-02-10 BE BE185100A patent/BE863883A/xx not_active IP Right Cessation
- 1978-02-10 NO NO780464A patent/NO148148C/no unknown
- 1978-02-13 FR FR7803961A patent/FR2380257A1/fr active Granted
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE20 | Patent expired |
Owner name: ISF S.P.A. Effective date: 19980210 |