IT1215581B - Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali. - Google Patents
Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali.Info
- Publication number
- IT1215581B IT1215581B IT8721046A IT2104687A IT1215581B IT 1215581 B IT1215581 B IT 1215581B IT 8721046 A IT8721046 A IT 8721046A IT 2104687 A IT2104687 A IT 2104687A IT 1215581 B IT1215581 B IT 1215581B
- Authority
- IT
- Italy
- Prior art keywords
- carbon atoms
- alcoss
- pyrolidine
- oxo
- benzyl
- Prior art date
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 206010003549 asthenia Diseases 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 possibly substituted Chemical group 0.000 abstract 1
- 230000009758 senescence Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8721046A IT1215581B (it) | 1987-06-25 | 1987-06-25 | Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali. |
| MX1197788A MX11977A (es) | 1987-06-25 | 1988-06-20 | Derivados de 1-bencil-2-oxo-5-alcoxi-pirrolidina y procedimiento para su preparacion. |
| ES198888401586T ES2037855T3 (es) | 1987-06-25 | 1988-06-23 | Procedimiento para preparar nuevos derivados de 1-bencil-2-oxo-5-alcoxi-pirrolidina. |
| DE8888401586T DE3864760D1 (de) | 1987-06-25 | 1988-06-23 | 1-benzyl 2-oxo 5-alkoxy pyrrolidin-derivate, verfahren zur herstellung, zusammenstellungen, die sie enthalten, und ihre verwendung als heilmittel. |
| AT88401586T ATE67183T1 (de) | 1987-06-25 | 1988-06-23 | 1-benzyl 2-oxo 5-alkoxy pyrrolidin-derivate, verfahren zur herstellung, zusammenstellungen, die sie enthalten, und ihre verwendung als heilmittel. |
| EP88401586A EP0296978B1 (fr) | 1987-06-25 | 1988-06-23 | Nouveaux dérivés de 1-benzyl 2-oxo 5-alcoxy pyrrolidine, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant |
| CA000570245A CA1311487C (fr) | 1987-06-25 | 1988-06-23 | Derives de 1-benzyl 2-oxo 5-alcoxy pyrrolidine, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
| PT87818A PT87818B (pt) | 1987-06-25 | 1988-06-24 | Processo para a preparacao de novos derivados de 1-benzil 2-oxo-5-alcoxi-pirrolidina |
| JP63155077A JPS6426553A (en) | 1987-06-25 | 1988-06-24 | Novel derivative of 1-benzyl-2-oxo-5-alkoxy- pyrrolidine, manufacture, use as drug and composition |
| US07/211,288 US4882350A (en) | 1987-06-25 | 1988-06-24 | Derivatives of 1-benzyl-2-oxo-5-alkoxy-pyrrolidine, and medicament compositions containing them |
| GR91400802T GR3002695T3 (en) | 1987-06-25 | 1991-09-12 | 1-benzyl 2-oxo 5-alkoxy pyrrolidine derivatives, process for their preparation, compositions containing them and their use in medicines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8721046A IT1215581B (it) | 1987-06-25 | 1987-06-25 | Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8721046A0 IT8721046A0 (it) | 1987-06-25 |
| IT1215581B true IT1215581B (it) | 1990-02-14 |
Family
ID=11175908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8721046A IT1215581B (it) | 1987-06-25 | 1987-06-25 | Derivati della 1-benzil 2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro applicazione come prodotti medicinali. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4882350A (it) |
| EP (1) | EP0296978B1 (it) |
| JP (1) | JPS6426553A (it) |
| AT (1) | ATE67183T1 (it) |
| CA (1) | CA1311487C (it) |
| DE (1) | DE3864760D1 (it) |
| ES (1) | ES2037855T3 (it) |
| GR (1) | GR3002695T3 (it) |
| IT (1) | IT1215581B (it) |
| MX (1) | MX11977A (it) |
| PT (1) | PT87818B (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0557186U (ja) * | 1991-12-27 | 1993-07-30 | ミサワホーム株式会社 | 畳敷き構造 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3117975A (en) * | 1960-04-22 | 1964-01-14 | Rohm & Haas | Substituted pyrrolidinones and piperidinones |
| NL263867A (it) * | 1960-04-22 | |||
| US3423426A (en) * | 1966-01-25 | 1969-01-21 | Chevron Res | N-(polyhaloalkylthio) alkenylsuccinimides |
| US3686169A (en) * | 1970-07-20 | 1972-08-22 | Monsanto Co | Thiocycloamides |
| US4138408A (en) * | 1975-12-20 | 1979-02-06 | Hoechst Aktiengesellschaft | ω-Alkoxy derivatives of lactams and process for their manufacture |
| IT1075280B (it) * | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| FR2553409B1 (fr) * | 1983-10-18 | 1986-04-18 | Choay Sa | Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques |
| JP3027332B2 (ja) * | 1996-06-14 | 2000-04-04 | ハウス食品株式会社 | ペースト状ケーキの素又はルウ、およびその製造方法 |
-
1987
- 1987-06-25 IT IT8721046A patent/IT1215581B/it active
-
1988
- 1988-06-20 MX MX1197788A patent/MX11977A/es unknown
- 1988-06-23 CA CA000570245A patent/CA1311487C/fr not_active Expired - Fee Related
- 1988-06-23 AT AT88401586T patent/ATE67183T1/de active
- 1988-06-23 ES ES198888401586T patent/ES2037855T3/es not_active Expired - Lifetime
- 1988-06-23 DE DE8888401586T patent/DE3864760D1/de not_active Expired - Fee Related
- 1988-06-23 EP EP88401586A patent/EP0296978B1/fr not_active Expired - Lifetime
- 1988-06-24 US US07/211,288 patent/US4882350A/en not_active Expired - Fee Related
- 1988-06-24 JP JP63155077A patent/JPS6426553A/ja active Pending
- 1988-06-24 PT PT87818A patent/PT87818B/pt not_active IP Right Cessation
-
1991
- 1991-09-12 GR GR91400802T patent/GR3002695T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3864760D1 (de) | 1991-10-17 |
| ES2037855T3 (es) | 1993-07-01 |
| CA1311487C (fr) | 1992-12-15 |
| MX11977A (es) | 1993-11-01 |
| IT8721046A0 (it) | 1987-06-25 |
| PT87818A (pt) | 1989-05-31 |
| GR3002695T3 (en) | 1993-01-25 |
| EP0296978B1 (fr) | 1991-09-11 |
| US4882350A (en) | 1989-11-21 |
| EP0296978A3 (en) | 1989-08-09 |
| ATE67183T1 (de) | 1991-09-15 |
| JPS6426553A (en) | 1989-01-27 |
| EP0296978A2 (fr) | 1988-12-28 |
| PT87818B (pt) | 1992-10-30 |
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