IT1215587B - Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale. - Google Patents

Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.

Info

Publication number
IT1215587B
IT1215587B IT8721079A IT2107987A IT1215587B IT 1215587 B IT1215587 B IT 1215587B IT 8721079 A IT8721079 A IT 8721079A IT 2107987 A IT2107987 A IT 2107987A IT 1215587 B IT1215587 B IT 1215587B
Authority
IT
Italy
Prior art keywords
carbon atoms
radical containing
benzoil2
alcossi
pirrolidina
Prior art date
Application number
IT8721079A
Other languages
English (en)
Other versions
IT8721079A0 (it
Inventor
Giuliano Galliani
Fernando Barzaghi
Carlo Zirotti
Emilio Toja
Original Assignee
Roussel Maestretti Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Maestretti Spa filed Critical Roussel Maestretti Spa
Publication of IT8721079A0 publication Critical patent/IT8721079A0/it
Priority to IT8721079A priority Critical patent/IT1215587B/it
Priority to MX1197688A priority patent/MX11976A/es
Priority to CA000570244A priority patent/CA1308728C/fr
Priority to EP88401587A priority patent/EP0296979B1/fr
Priority to DE8888401587T priority patent/DE3866603D1/de
Priority to ES198888401587T priority patent/ES2039284T3/es
Priority to AT88401587T priority patent/ATE70050T1/de
Priority to JP63155078A priority patent/JPS6426554A/ja
Priority to US07/211,287 priority patent/US4948804A/en
Priority to PT87819A priority patent/PT87819B/pt
Application granted granted Critical
Publication of IT1215587B publication Critical patent/IT1215587B/it
Priority to GR91402207T priority patent/GR3003472T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT8721079A 1987-06-26 1987-06-26 Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale. IT1215587B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT8721079A IT1215587B (it) 1987-06-26 1987-06-26 Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.
MX1197688A MX11976A (es) 1987-06-26 1988-06-20 Procedimiento para preparar derivados de 1-benzoil-2-oxo-5-alcoxi-pirrolidina y producto obtenido.
DE8888401587T DE3866603D1 (de) 1987-06-26 1988-06-23 1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten.
EP88401587A EP0296979B1 (fr) 1987-06-26 1988-06-23 Dérivés de la 1-benzoyl 2-oxo 5-alcoxy pyrrolidine, leur préparation, leur application comme médicament et les compositions les renfermant
CA000570244A CA1308728C (fr) 1987-06-26 1988-06-23 Derives de la 1-benzoyl 2-oxo 5-alcoxy pyrrolidine, leur preparation, leur application comme medicament et les compositions les renfermant
ES198888401587T ES2039284T3 (es) 1987-06-26 1988-06-23 Un procedimiento para preparar derivados de la 1-benzoil-2-oxo-5-alcoxi-pirrolidina.
AT88401587T ATE70050T1 (de) 1987-06-26 1988-06-23 1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten.
JP63155078A JPS6426554A (en) 1987-06-26 1988-06-24 Novel derivative of 1-benzoyl-2-oxo-5-alkoxy pyrrolidine, manufacture, use as drug and composition
US07/211,287 US4948804A (en) 1987-06-26 1988-06-24 Derivatives of 1-benzoyl 2-oxo 5-alkoxy pyrrolidine, their preparation, their use as medicaments and the compositions containing them
PT87819A PT87819B (pt) 1987-06-26 1988-06-24 Processo para a preparacao de novos derivados de 1-benzoil 2-oxo-5-alcoxi pirrolidina
GR91402207T GR3003472T3 (en) 1987-06-26 1991-12-30 1-benzoyl-2-oxo-5-alkoxy-pyrrolidine derivatives, their preparation, their use and preparations containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721079A IT1215587B (it) 1987-06-26 1987-06-26 Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.

Publications (2)

Publication Number Publication Date
IT8721079A0 IT8721079A0 (it) 1987-06-26
IT1215587B true IT1215587B (it) 1990-02-14

Family

ID=11176429

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8721079A IT1215587B (it) 1987-06-26 1987-06-26 Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.

Country Status (11)

Country Link
US (1) US4948804A (it)
EP (1) EP0296979B1 (it)
JP (1) JPS6426554A (it)
AT (1) ATE70050T1 (it)
CA (1) CA1308728C (it)
DE (1) DE3866603D1 (it)
ES (1) ES2039284T3 (it)
GR (1) GR3003472T3 (it)
IT (1) IT1215587B (it)
MX (1) MX11976A (it)
PT (1) PT87819B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720930B2 (ja) * 1988-07-09 1995-03-08 明治製菓株式会社 ピロリジノン化合物及び脳機能障害改善剤
PT651746E (pt) * 1992-07-24 2002-09-30 Univ California Drogas que intensificam as respostas sinapticas mediadas por receptores de ampa
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
JPH09145713A (ja) * 1995-11-21 1997-06-06 Asahi Optical Co Ltd 抗原又は抗体の検査材の評価方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2915430A (en) * 1958-09-30 1959-12-01 Gen Aniline & Film Corp Method of controlling nematodes with n-acylpyrrolidones
US3117975A (en) * 1960-04-22 1964-01-14 Rohm & Haas Substituted pyrrolidinones and piperidinones
US3423426A (en) * 1966-01-25 1969-01-21 Chevron Res N-(polyhaloalkylthio) alkenylsuccinimides
US3686169A (en) * 1970-07-20 1972-08-22 Monsanto Co Thiocycloamides
NL7609725A (nl) * 1975-09-06 1977-03-08 Hoechst Ag Alkoxyderivaten van aan de n gesubstitueerde cyclische aminen en werkwijze voor hun be- reiding.
CA1115212A (en) * 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
CA1124247A (en) * 1979-08-09 1982-05-25 Hoffmann-La Roche Limited Pyrrolidine derivatives
CH646149A5 (de) * 1981-02-05 1984-11-15 Hoffmann La Roche Pyrrolidin-derivat.
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
US4772601A (en) * 1988-01-25 1988-09-20 Hoechst-Roussel Pharmaceuticals, Inc. 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use

Also Published As

Publication number Publication date
PT87819B (pt) 1992-10-30
IT8721079A0 (it) 1987-06-26
DE3866603D1 (de) 1992-01-16
GR3003472T3 (en) 1993-02-17
US4948804A (en) 1990-08-14
ES2039284T3 (es) 1993-09-16
EP0296979A2 (fr) 1988-12-28
EP0296979B1 (fr) 1991-12-04
EP0296979A3 (en) 1989-08-16
CA1308728C (fr) 1992-10-13
PT87819A (pt) 1989-05-31
MX11976A (es) 1993-11-01
ATE70050T1 (de) 1991-12-15
JPS6426554A (en) 1989-01-27

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