ATE49957T1 - Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel. - Google Patents

Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel.

Info

Publication number
ATE49957T1
ATE49957T1 AT85401976T AT85401976T ATE49957T1 AT E49957 T1 ATE49957 T1 AT E49957T1 AT 85401976 T AT85401976 T AT 85401976T AT 85401976 T AT85401976 T AT 85401976T AT E49957 T1 ATE49957 T1 AT E49957T1
Authority
AT
Austria
Prior art keywords
derivatives
adamantanamine
preparation
medications containing
medications
Prior art date
Application number
AT85401976T
Other languages
English (en)
Inventor
Claude Laruelle
Marcel Lepant
Bernard Raynier
Original Assignee
Panmedica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panmedica Sa filed Critical Panmedica Sa
Application granted granted Critical
Publication of ATE49957T1 publication Critical patent/ATE49957T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT85401976T 1984-10-31 1985-10-10 Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel. ATE49957T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8416656A FR2572399B1 (fr) 1984-10-31 1984-10-31 Nouveaux derives de l'adamantanamine, leurs procedes de preparation et medicaments les contenant
EP85401976A EP0187052B1 (de) 1984-10-31 1985-10-10 Adamantanamin-Derivate, Verfahren zur Herstellung und diese enthaltende Heilmittel

Publications (1)

Publication Number Publication Date
ATE49957T1 true ATE49957T1 (de) 1990-02-15

Family

ID=9309181

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85401976T ATE49957T1 (de) 1984-10-31 1985-10-10 Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel.

Country Status (10)

Country Link
US (1) US4661512A (de)
EP (1) EP0187052B1 (de)
JP (1) JPS61109766A (de)
KR (1) KR920003837B1 (de)
AT (1) ATE49957T1 (de)
AU (1) AU583543B2 (de)
DE (1) DE3575715D1 (de)
ES (1) ES8702888A1 (de)
FR (1) FR2572399B1 (de)
ZA (1) ZA858169B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609152A1 (de) * 1986-03-19 1987-09-24 Bayer Ag Verfahren zur herstellung des (-)-antipoden des (e)-1-cyclohexyl-4,4-dimethyl- 3-hydroxy-2-(1,2,4-triazol-1-yl)-pent-1-ens
US5236946A (en) * 1986-09-16 1993-08-17 Panmedica S.A. Amino acid esters of cycloaliphatic alcohols and their use in treating lipemic disorders
FR2603888B1 (fr) * 1986-09-16 1990-12-21 Panmedica Sa Esters d'amino acides du trimethyl cyclohexanol, procede de preparation et utilisation comme medicaments
US5652335A (en) * 1990-02-28 1997-07-29 Teikoku Seiyaku Kabushiki Kaisha Physiologically active substance well capable of permeating biomembrane
DE69130489T2 (de) * 1990-02-28 1999-05-12 Teikoku Seiyaku Kk Physiologisch aktive Substanz die fähig ist Biomembran zu permeieren
AU6391594A (en) * 1994-02-01 1995-08-21 Board Of Regents Of The University Of Nebraska, The Polymeric adamantane analogues
US5880154A (en) * 1994-02-01 1999-03-09 The Board Of Regents Of The University Of Nebraska Polymeric adamantane analogues
EP0842164A4 (de) * 1995-07-07 1998-10-07 Durham Pharmaceuticals Llc Cyclische amide und derivate davon
ES2175614T3 (es) * 1997-04-10 2002-11-16 Pfizer Derivados fluorosustituidos de adamantano.
CO5150173A1 (es) * 1998-12-10 2002-04-29 Novartis Ag Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
US6159485A (en) 1999-01-08 2000-12-12 Yugenic Limited Partnership N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use
US6808716B2 (en) * 1999-01-08 2004-10-26 Ruey J. Yu N-acetylamino acids, related N-acetyl compounds and their topical use
DE60326232D1 (de) * 2002-06-03 2009-04-02 Novartis Ag Verwendung von substituierten cyanopyrrolidinen zur behandlung von hyperlipidämie
WO2005108359A1 (en) * 2004-05-06 2005-11-17 Pfizer Inc. Novel compounds of proline and morpholine derivatives
JP2007102047A (ja) * 2005-10-07 2007-04-19 Dainippon Printing Co Ltd 商品管理用タグ

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3152180A (en) * 1960-08-25 1964-10-06 Studiengesellschaft Kohle Mbh Process for the production of nu-tert-alkyl amides and, if desired, nu-tert. alkyl amines
FR2622M (fr) * 1962-12-29 1964-06-29 Mundipharma Ag Nouveaux composés thérapeutiques.
US3345399A (en) * 1965-01-21 1967-10-03 Lilly Co Eli Carbamate esters of adamantane, mono-and di-methyladamantane and homoadamantane
US3374244A (en) * 1966-06-13 1968-03-19 Searle & Co N-(dialkylaminoalkyl)adamantanecarboxamides and related compounds
US3478055A (en) * 1966-06-15 1969-11-11 Tanabe Seiyaku Co Production of optically active n-acylprolines and prolines
US3682922A (en) * 1969-01-16 1972-08-08 Searle & Co N-acyl-n-{8 (n{40 ,n{40 -disubstituted amino)-alkyl{9 -1-adamantylmethylamines
BE754823A (fr) * 1969-08-13 1971-01-18 Merz & Co Derives de l'amonioadamantane et leur procede de preparation
JPS5581857A (en) * 1978-12-15 1980-06-20 Kyowa Hakko Kogyo Co Ltd Modifier of citrus fruit
US4273704A (en) * 1979-12-03 1981-06-16 G. D. Searle & Co. N-Adamantane-substituted tetrapeptide amides
US4296110A (en) * 1980-10-28 1981-10-20 E. I. Du Pont De Nemours And Company Antihypertensive I-substituted cyclic lactam-2-carboxylic acids
JPS5865269A (ja) * 1981-10-12 1983-04-18 Suntory Ltd ４置換（２ｓ，３ｓ，４ｓ）−２−カルボキシピロリジン−３−酢酸およびそのエステル
US4448972A (en) * 1982-02-22 1984-05-15 Smithkline Beckman Corporation Adamantyl containing intermediates
CS231221B1 (en) * 1982-06-29 1984-10-15 Martin Flegel L-alanyl-d-isoglutamine adamantylamide

Also Published As

Publication number Publication date
FR2572399A1 (fr) 1986-05-02
DE3575715D1 (de) 1990-03-08
AU583543B2 (en) 1989-05-04
US4661512A (en) 1987-04-28
ES8702888A1 (es) 1987-01-16
FR2572399B1 (fr) 1987-01-16
EP0187052A1 (de) 1986-07-09
AU4884685A (en) 1986-05-08
KR920003837B1 (ko) 1992-05-15
JPS61109766A (ja) 1986-05-28
KR860003219A (ko) 1986-05-21
ZA858169B (en) 1986-06-25
EP0187052B1 (de) 1990-01-31
ES548357A0 (es) 1987-01-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee