PT87819A - Procede de preparation de nouveaux derives de la 1-benzoyl 2-oxo 5-alcoxy pyrrolidine - Google Patents

Procede de preparation de nouveaux derives de la 1-benzoyl 2-oxo 5-alcoxy pyrrolidine

Info

Publication number
PT87819A
PT87819A PT87819A PT8781988A PT87819A PT 87819 A PT87819 A PT 87819A PT 87819 A PT87819 A PT 87819A PT 8781988 A PT8781988 A PT 8781988A PT 87819 A PT87819 A PT 87819A
Authority
PT
Portugal
Prior art keywords
carbon atoms
preparation
radical containing
procede
alcoxy
Prior art date
Application number
PT87819A
Other languages
English (en)
Other versions
PT87819B (pt
Inventor
Giulio Galliani
Fernando Barzaghi
Carlo Zirotti
Emilio Toja
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT87819A publication Critical patent/PT87819A/pt
Publication of PT87819B publication Critical patent/PT87819B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT87819A 1987-06-26 1988-06-24 Processo para a preparacao de novos derivados de 1-benzoil 2-oxo-5-alcoxi pirrolidina PT87819B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721079A IT1215587B (it) 1987-06-26 1987-06-26 Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.

Publications (2)

Publication Number Publication Date
PT87819A true PT87819A (pt) 1989-05-31
PT87819B PT87819B (pt) 1992-10-30

Family

ID=11176429

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87819A PT87819B (pt) 1987-06-26 1988-06-24 Processo para a preparacao de novos derivados de 1-benzoil 2-oxo-5-alcoxi pirrolidina

Country Status (11)

Country Link
US (1) US4948804A (pt)
EP (1) EP0296979B1 (pt)
JP (1) JPS6426554A (pt)
AT (1) ATE70050T1 (pt)
CA (1) CA1308728C (pt)
DE (1) DE3866603D1 (pt)
ES (1) ES2039284T3 (pt)
GR (1) GR3003472T3 (pt)
IT (1) IT1215587B (pt)
MX (1) MX11976A (pt)
PT (1) PT87819B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720930B2 (ja) * 1988-07-09 1995-03-08 明治製菓株式会社 ピロリジノン化合物及び脳機能障害改善剤
ES2210060T3 (es) * 1992-07-24 2004-07-01 The Regents Of The University Of California Farmacos que aumentan las respuestas sinapticas mediadas por receptores ampa.
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
JPH09145713A (ja) * 1995-11-21 1997-06-06 Asahi Optical Co Ltd 抗原又は抗体の検査材の評価方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2915430A (en) * 1958-09-30 1959-12-01 Gen Aniline & Film Corp Method of controlling nematodes with n-acylpyrrolidones
US3117975A (en) * 1960-04-22 1964-01-14 Rohm & Haas Substituted pyrrolidinones and piperidinones
US3423426A (en) * 1966-01-25 1969-01-21 Chevron Res N-(polyhaloalkylthio) alkenylsuccinimides
US3686169A (en) * 1970-07-20 1972-08-22 Monsanto Co Thiocycloamides
NL7609725A (nl) * 1975-09-06 1977-03-08 Hoechst Ag Alkoxyderivaten van aan de n gesubstitueerde cyclische aminen en werkwijze voor hun be- reiding.
CA1115212A (en) * 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
NL8004025A (nl) * 1979-08-09 1981-02-11 Hoffmann La Roche Pyrrolidinederivaten en werkwijze voor het bereiden daarvan alsmede geneesmiddel.
CH646149A5 (de) * 1981-02-05 1984-11-15 Hoffmann La Roche Pyrrolidin-derivat.
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
US4772601A (en) * 1988-01-25 1988-09-20 Hoechst-Roussel Pharmaceuticals, Inc. 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use

Also Published As

Publication number Publication date
PT87819B (pt) 1992-10-30
CA1308728C (fr) 1992-10-13
IT8721079A0 (it) 1987-06-26
ATE70050T1 (de) 1991-12-15
MX11976A (es) 1993-11-01
US4948804A (en) 1990-08-14
EP0296979B1 (fr) 1991-12-04
EP0296979A3 (en) 1989-08-16
DE3866603D1 (de) 1992-01-16
JPS6426554A (en) 1989-01-27
IT1215587B (it) 1990-02-14
ES2039284T3 (es) 1993-09-16
EP0296979A2 (fr) 1988-12-28
GR3003472T3 (en) 1993-02-17

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920416

NF3A Restitutio in integrum

Effective date: 19940315

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19951031