ES2039284T3 - Un procedimiento para preparar derivados de la 1-benzoil-2-oxo-5-alcoxi-pirrolidina. - Google Patents

Un procedimiento para preparar derivados de la 1-benzoil-2-oxo-5-alcoxi-pirrolidina.

Info

Publication number
ES2039284T3
ES2039284T3 ES198888401587T ES88401587T ES2039284T3 ES 2039284 T3 ES2039284 T3 ES 2039284T3 ES 198888401587 T ES198888401587 T ES 198888401587T ES 88401587 T ES88401587 T ES 88401587T ES 2039284 T3 ES2039284 T3 ES 2039284T3
Authority
ES
Spain
Prior art keywords
pirrolidina
benzoil
alcoxi
oxo
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888401587T
Other languages
English (en)
Inventor
Giulio Galliani
Fernando Barzaghi
Carlo Zirotti
Emilio Toja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of ES2039284T3 publication Critical patent/ES2039284T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION TIENE POR OBJETO LOS COMPUESTOS DE FORMULA (I) EN LA QUER Y R'' TIENEN EL SIGNIFICADO QUE SE DETALLA EN LA INVENCION. APLICACION COMO MEDICAMENTOS Y LAS COMPOSICIONES QUE LAS CONTIENEN.
ES198888401587T 1987-06-26 1988-06-23 Un procedimiento para preparar derivados de la 1-benzoil-2-oxo-5-alcoxi-pirrolidina. Expired - Lifetime ES2039284T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721079A IT1215587B (it) 1987-06-26 1987-06-26 Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.

Publications (1)

Publication Number Publication Date
ES2039284T3 true ES2039284T3 (es) 1993-09-16

Family

ID=11176429

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888401587T Expired - Lifetime ES2039284T3 (es) 1987-06-26 1988-06-23 Un procedimiento para preparar derivados de la 1-benzoil-2-oxo-5-alcoxi-pirrolidina.

Country Status (11)

Country Link
US (1) US4948804A (es)
EP (1) EP0296979B1 (es)
JP (1) JPS6426554A (es)
AT (1) ATE70050T1 (es)
CA (1) CA1308728C (es)
DE (1) DE3866603D1 (es)
ES (1) ES2039284T3 (es)
GR (1) GR3003472T3 (es)
IT (1) IT1215587B (es)
MX (1) MX11976A (es)
PT (1) PT87819B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720930B2 (ja) * 1988-07-09 1995-03-08 明治製菓株式会社 ピロリジノン化合物及び脳機能障害改善剤
EP1156043B1 (en) * 1992-07-24 2003-11-12 The Regents Of The University Of California Drugs that enhance synaptic responses mediated by ampa receptors
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
JPH09145713A (ja) * 1995-11-21 1997-06-06 Asahi Optical Co Ltd 抗原又は抗体の検査材の評価方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2915430A (en) * 1958-09-30 1959-12-01 Gen Aniline & Film Corp Method of controlling nematodes with n-acylpyrrolidones
US3117975A (en) * 1960-04-22 1964-01-14 Rohm & Haas Substituted pyrrolidinones and piperidinones
US3423426A (en) * 1966-01-25 1969-01-21 Chevron Res N-(polyhaloalkylthio) alkenylsuccinimides
US3686169A (en) * 1970-07-20 1972-08-22 Monsanto Co Thiocycloamides
NL7609725A (nl) * 1975-09-06 1977-03-08 Hoechst Ag Alkoxyderivaten van aan de n gesubstitueerde cyclische aminen en werkwijze voor hun be- reiding.
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
CA1115212A (en) * 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
IT1131959B (it) * 1979-08-09 1986-06-25 Hoffmann La Roche Derivati pirrolidinici
CH646149A5 (de) * 1981-02-05 1984-11-15 Hoffmann La Roche Pyrrolidin-derivat.
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
US4772601A (en) * 1988-01-25 1988-09-20 Hoechst-Roussel Pharmaceuticals, Inc. 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use

Also Published As

Publication number Publication date
IT1215587B (it) 1990-02-14
EP0296979B1 (fr) 1991-12-04
GR3003472T3 (en) 1993-02-17
EP0296979A2 (fr) 1988-12-28
MX11976A (es) 1993-11-01
US4948804A (en) 1990-08-14
JPS6426554A (en) 1989-01-27
PT87819B (pt) 1992-10-30
ATE70050T1 (de) 1991-12-15
IT8721079A0 (it) 1987-06-26
DE3866603D1 (de) 1992-01-16
PT87819A (pt) 1989-05-31
EP0296979A3 (en) 1989-08-16
CA1308728C (fr) 1992-10-13

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