GB1495679A
(en)
*
|
1974-06-17 |
1977-12-21 |
Mallinckrodt Inc |
Substituted isophthalamic acids
|
US4314055A
(en)
*
|
1975-09-29 |
1982-02-02 |
Mallinckrodt, Inc. |
3,5-Disubstituted-2,4,6-triiodoanilides of polyhydroxy-monobasic acids
|
JPS52130923A
(en)
*
|
1976-04-27 |
1977-11-02 |
Mallinckrodt Chemical Works |
Xxray photographic agent
|
CH626873A5
(sl)
*
|
1977-03-28 |
1981-12-15 |
Bracco Ind Chimica Spa |
|
DE2909439A1
(de)
*
|
1979-03-08 |
1980-09-18 |
Schering Ag |
Neue nichtionische roentgenkontrastmittel
|
US4256729A
(en)
*
|
1979-03-23 |
1981-03-17 |
Mallinckrodt, Inc. |
N,N'-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-L-gulonamido)isophthalamide and radiological compositions containing same
|
NL8002388A
(nl)
*
|
1979-05-21 |
1980-11-25 |
Mallinckrodt Inc |
Roentgencontrastmiddel.
|
IT1207226B
(it)
*
|
1979-08-09 |
1989-05-17 |
Bracco Ind Chimica Spa |
Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
|
DE3001292A1
(de)
*
|
1980-01-11 |
1981-07-16 |
Schering Ag Berlin Und Bergkamen, 1000 Berlin |
Nichtionische 5-c-substituierte 2,4,6-trijod-isophthalsaeure-derivate
|
DE3038853A1
(de)
|
1980-10-10 |
1982-05-27 |
Schering Ag, 1000 Berlin Und 4619 Bergkamen |
Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
|
DE3150916A1
(de)
*
|
1981-12-18 |
1983-06-30 |
Schering Ag, 1000 Berlin Und 4619 Bergkamen |
N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
|
US4396598A
(en)
*
|
1982-01-11 |
1983-08-02 |
Mallinckrodt, Inc. |
Triiodoisophthalamide X-ray contrast agent
|
US5204086A
(en)
*
|
1982-10-01 |
1993-04-20 |
Nycomed Imaging As |
X-ray contrast agent
|
US4584401A
(en)
*
|
1983-10-20 |
1986-04-22 |
Biophysica Foundation |
Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
|
DE3689330T2
(de)
*
|
1985-08-09 |
1994-05-19 |
Cook Imaging Corp |
Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln.
|
US5035877A
(en)
*
|
1985-08-09 |
1991-07-30 |
Cook Imaging Corporation |
Non-ionic contrast media from ionic contrast media
|
KR960016747B1
(ko)
*
|
1987-05-22 |
1996-12-20 |
브라코 인터내셔날 비. 브이 |
5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법
|
IL94718A
(en)
*
|
1989-07-05 |
1994-10-21 |
Schering Ag |
Non-ionic carboxamide contrast agent and method of preparation
|
US5698739A
(en)
*
|
1989-07-05 |
1997-12-16 |
Schering Aktiengesellschaft |
Carboxamide non-ionic contrast media
|
US5232685A
(en)
*
|
1989-11-03 |
1993-08-03 |
Schering Aktiengesellschaft |
Nonionic x-ray contrast medium with high iodine content
|
DE3937118A1
(de)
*
|
1989-11-03 |
1991-05-08 |
Schering Ag |
Nichtionische roentgenkontrastmittel mit hohem jodgehalt
|
US5614638A
(en)
*
|
1989-11-29 |
1997-03-25 |
Bracco International B.V. |
Nonionic radiographic contrast agents
|
US5075502A
(en)
*
|
1989-12-13 |
1991-12-24 |
Mallinckrodt, Inc. |
Nonionic x-ray contrast agents, compositions and methods
|
US4997983A
(en)
*
|
1990-01-31 |
1991-03-05 |
Mallinckrodt, Inc. |
Process for production of ioversol
|
IT1248741B
(it)
*
|
1991-02-26 |
1995-01-26 |
Bracco Spa |
Processo di concentrazione e di purificazione di composti organici
|
US5169864A
(en)
*
|
1991-11-15 |
1992-12-08 |
Baxter International Inc. |
Unbuffered premixed ranitidine formulation
|
US5463080A
(en)
*
|
1992-08-27 |
1995-10-31 |
Bracco International B.V. |
2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents
|
IT1256162B
(it)
*
|
1992-10-27 |
1995-11-29 |
Zambon Spa |
Processo per la preparazione di un intermedio della sintesi organica
|
IT1256163B
(it)
*
|
1992-10-27 |
1995-11-29 |
Zambon Spa |
Processo per la preparazione di un intermedio della sintesi organica
|
IT1256248B
(it)
*
|
1992-12-24 |
1995-11-29 |
Bracco Spa |
Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
|
US5424056A
(en)
*
|
1993-03-01 |
1995-06-13 |
Sterling Wintrhop Inc. |
X-ray contrast compositions containing iodoaniline derivatives and pharmaceutically acceptable clays
|
US5330740A
(en)
*
|
1993-03-01 |
1994-07-19 |
Sterling Winthrop Inc. |
Compositions of iodoaniline derivatives in film-forming materials for visualization of the gastrointestinal tract
|
IL110391A
(en)
|
1993-07-30 |
1998-12-06 |
Zambon Spa |
Process for the formation of infamidol
|
IT1271469B
(it)
*
|
1993-09-10 |
1997-05-28 |
Zambon Spa |
Processo per la preparazione di 5-ammino-2,2-dialchil-1,3 diossani
|
IT1274027B
(it)
*
|
1994-03-03 |
1997-07-14 |
Zambon Spa |
Processo per la preparazione e purificazione di mezzi di contrasto iodurati
|
IT1275429B
(it)
*
|
1995-05-18 |
1997-08-07 |
Zambon Spa |
Processo per la preparazione di un intermedio utile nella sintesi di composti organici
|
KR100255914B1
(ko)
*
|
1995-05-23 |
2000-05-01 |
안토니오 칸탈루피 |
디카르복실산 디클로라이드의 제조 방법
|
PL187308B1
(pl)
|
1995-05-23 |
2004-06-30 |
Bracco Imaging Spa |
Sposób wytwarzania dichlorku kwasu dikarboksylowego i sposób oczyszczania i izolacji dichlorku kwasu dikarboksylowego
|
PT101720A
(pt)
*
|
1995-06-08 |
1997-01-31 |
Hovione Sociedade Quimica S A |
Processo para a purificacao e cristalizacao de iopamidol
|
ATE187437T1
(de)
*
|
1995-09-08 |
1999-12-15 |
Bracco Int Bv |
Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide
|
US5866100A
(en)
*
|
1995-12-19 |
1999-02-02 |
Bracco Research S.A. |
Compositions for imaging of the gastrointestinal tract
|
IT1283319B1
(it)
*
|
1996-03-29 |
1998-04-16 |
Zambon Spa |
Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
|
IT1288114B1
(it)
*
|
1996-06-13 |
1998-09-10 |
Fructamine Spa |
Processo per la purificazione di un intermedio
|
GB9618056D0
(en)
*
|
1996-08-29 |
1996-10-09 |
Nycomed Imaging As |
Process
|
US5705692A
(en)
*
|
1996-09-27 |
1998-01-06 |
Abbott Laboratories |
Process for the preparation of iohexol
|
US5861138A
(en)
*
|
1996-11-20 |
1999-01-19 |
Hoechst Celanese Corp. |
Ligands for MRI contrast agent
|
US5861140A
(en)
*
|
1996-11-20 |
1999-01-19 |
Hoechst Celanese Corp. |
Tripodal paramagnetic contrast agents for MR imaging
|
GB9624612D0
(en)
*
|
1996-11-26 |
1997-01-15 |
Nycomed Imaging As |
Process
|
IT1286522B1
(it)
*
|
1996-12-04 |
1998-07-15 |
Dibra Spa |
Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico
|
IT1289520B1
(it)
*
|
1996-12-24 |
1998-10-15 |
Zambon Spa |
Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
|
IT1289521B1
(it)
*
|
1996-12-24 |
1998-10-15 |
Zambon Spa |
Processo per la purificazione di un intermedio
|
IT1289519B1
(it)
*
|
1996-12-24 |
1998-10-15 |
Zambon Spa |
Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
|
DE966428T1
(de)
*
|
1997-02-11 |
2000-06-29 |
Bracco International B.V., Amsterdam |
Verfahren zur kritallisation von (s)-n-n'-bis [2-hydroxy-1-(hydroxymethyl) ethyl]-5-[(2-hydroxy-1-xopropyl) amino]-2,4,6-trirodo-1,3-benzoldicarboxamid aus linearem oder verzweigtem (c5-c6) alkohol oder gemischen davon
|
IT1292037B1
(it)
*
|
1997-05-30 |
1999-01-25 |
Bracco Spa |
Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
|
US5869025A
(en)
*
|
1997-08-21 |
1999-02-09 |
Hoechst Celanese Corporation |
Tripodal aromatic heterocycle carboxamide MRI contrast agents
|
US5858329A
(en)
*
|
1997-08-21 |
1999-01-12 |
Hoechst Celanese Corporation |
MRI diagnostic procedures using tripodal pyridinyl metal complexes
|
US5820851A
(en)
*
|
1997-08-21 |
1998-10-13 |
Hoechst Celanese Corporation |
Tripodal pyridine ligands as MRI contrast agents
|
US5824288A
(en)
*
|
1997-08-21 |
1998-10-20 |
Hoechst Celanese Corporation |
Thio-substituted pyridines as MRI ligand precursors
|
US5869026A
(en)
*
|
1997-08-21 |
1999-02-09 |
Hoechst Celanese Corp. |
Tripodal carboxamide ligands for MRI contrast agents
|
US6262303B1
(en)
|
1998-05-08 |
2001-07-17 |
Dibra S.P.A. |
Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
|
IT1299202B1
(it)
*
|
1998-05-08 |
2000-02-29 |
Dibra Spa |
Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
|
IT1302200B1
(it)
*
|
1998-09-11 |
2000-07-31 |
Dibra Spa |
PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1-
|
GB9825095D0
(en)
*
|
1998-11-16 |
1999-01-13 |
Nycomed Imaging As |
Chemical process
|
US6803485B2
(en)
*
|
1999-02-26 |
2004-10-12 |
Bracco Imaging S.P.A. |
Process for the preparation of iopamidol
|
SE520688C2
(sv)
*
|
2000-04-11 |
2003-08-12 |
Bone Support Ab |
Ett injicerbart ersättningsmaterial för benmineral
|
SE517168C2
(sv)
*
|
2000-07-17 |
2002-04-23 |
Bone Support Ab |
En komposition för ett injicerbart ersättningsmaterial för benmineral
|
IT1319671B1
(it)
*
|
2000-12-01 |
2003-10-23 |
Bracco Spa |
Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino)
|
SE522098C2
(sv)
*
|
2001-12-20 |
2004-01-13 |
Bone Support Ab |
Ett nytt benmineralsubstitut
|
SE0300620D0
(sv)
*
|
2003-03-05 |
2003-03-05 |
Bone Support Ab |
A new bone substitute composition
|
SE0302983D0
(sv)
*
|
2003-11-11 |
2003-11-11 |
Bone Support Ab |
Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
|
SE527528C2
(sv)
|
2004-06-22 |
2006-04-04 |
Bone Support Ab |
Anordning för framställning av härdbar massa samt användning av anordningen
|
AU2008206953A1
(en)
*
|
2007-01-19 |
2008-07-24 |
Cinvention Ag |
Porous, non-degradable implant made by powder molding
|
US20080206862A1
(en)
*
|
2007-02-28 |
2008-08-28 |
Cinvention Ag |
High surface cultivation system bag
|
US7955234B1
(en)
|
2007-02-28 |
2011-06-07 |
Pursley Michael G |
Exercise device and method
|
EP2126040A1
(en)
*
|
2007-02-28 |
2009-12-02 |
Cinvention Ag |
High surface cultivation system
|
EP2093206A1
(en)
|
2008-02-20 |
2009-08-26 |
BRACCO IMAGING S.p.A. |
Process for the iodination of aromatic compounds
|
KR101098553B1
(ko)
*
|
2008-04-30 |
2011-12-26 |
주식회사 엘지생명과학 |
이오프로마이드의 신규한 제조방법
|
US8624061B2
(en)
*
|
2008-11-18 |
2014-01-07 |
Bracco Imaging S.P.A. |
Process for the preparation of iodinated contrast agent
|
US20110256068A1
(en)
|
2009-01-09 |
2011-10-20 |
Wistand Lars-Goeran |
Contrast media compositions
|
EP2230227A1
(en)
*
|
2009-03-20 |
2010-09-22 |
Bracco Imaging S.p.A |
Process for the preparation of triiodinated carboxylic aromatic derivatives
|
EP2243767A1
(en)
*
|
2009-04-21 |
2010-10-27 |
Bracco Imaging S.p.A |
Process for the iodination of aromatic compounds
|
DK2451994T3
(da)
|
2009-07-07 |
2014-01-20 |
Bracco Imaging Spa |
Fremgangsmåde til fremstilling af et ioderende middel
|
US9180137B2
(en)
|
2010-02-09 |
2015-11-10 |
Bone Support Ab |
Preparation of bone cement compositions
|
PT105770B
(pt)
*
|
2011-06-24 |
2013-07-08 |
Hovione Farmaciencia S A |
Novo intermediário e seu uso na preparação de agente de contrate triiodado
|
EP2931696B1
(en)
|
2012-12-11 |
2018-08-22 |
Bracco Imaging S.p.A |
Continuous process for the preparation of (s)-2-acetyloxypropionic acid
|
PT2958603T
(pt)
|
2013-02-20 |
2018-06-06 |
Bone Support Ab |
Endurecimento melhorado de substituto ósseo endurecível
|
LT3066071T
(lt)
*
|
2013-11-05 |
2018-09-10 |
Bracco Imaging S.P.A. |
Jopamidolio gamybos būdas
|
CA2949433C
(en)
|
2014-06-10 |
2022-05-03 |
Bracco Imaging Spa |
Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof
|
CN104230731B
(zh)
*
|
2014-09-24 |
2016-01-20 |
武汉理工大学 |
造影剂中间体三碘异酞酰氯的制备方法
|
PT108524B
(pt)
|
2015-06-02 |
2017-12-15 |
Hovione Farmaciência S A |
Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
|
CN105461581A
(zh)
*
|
2015-11-17 |
2016-04-06 |
浙江海洲制药有限公司 |
碘帕醇杂质a和杂质b的合成方法
|
CN107778191A
(zh)
*
|
2016-08-26 |
2018-03-09 |
正大天晴药业集团股份有限公司 |
一种碘普罗胺及其中间体的制备方法
|
WO2018104228A1
(en)
|
2016-12-05 |
2018-06-14 |
Bracco Imaging Spa |
Mechanochemical synthesis of radiographic agents intermediates
|
JP7132252B2
(ja)
|
2017-06-07 |
2022-09-06 |
ブラッコ・イメージング・ソシエタ・ペル・アチオニ |
水溶液からのヨウ素の回収方法
|
WO2022200247A1
(en)
|
2021-03-22 |
2022-09-29 |
Bracco Imaging Spa |
Industrial synthesis of serinol
|
WO2023117667A1
(en)
|
2021-12-20 |
2023-06-29 |
Bracco Imaging Spa |
Process for the preparation of 2,4,6-triiodoisophthalic bisamides
|