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Method of production of the bis-/dihydrixypropylamides/ of the acid 5-hydroxypropionylamino-2,4,6-troiodisophtale

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A61K49/0433 X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
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Chemical & Material Sciences Organic Chemistry
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CS194234B2

Czechoslovakia

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English
Inventor
Ernst Felder
Davide Pitre
Worldwide applications
1974 CH 1975 NL BG ES IL ZA US IN GB CA AR MX AT BE SU PL HU FR DD IE CS NO RO YU DK SE AU JP PH AT 1983 YU
Application CS758475A events
1975-12-12
Application filed by Savac Ag
1979-11-30
Publication of CS194234B2
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Patent citations (5)
Cited by (104)
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Patent Citations (5)

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US4256729A * 1979-03-23 1981-03-17 Mallinckrodt, Inc. N,N'-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-L-gulonamido)isophthalamide and radiological compositions containing same
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IT1207226B * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
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DE3150917A1 * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
DE3150916A1 * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
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IT1256248B * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5424056A * 1993-03-01 1995-06-13 Sterling Wintrhop Inc. X-ray contrast compositions containing iodoaniline derivatives and pharmaceutically acceptable clays
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IT1288114B1 * 1996-06-13 1998-09-10 Fructamine Spa Processo per la purificazione di un intermedio
GB9618056D0 * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US5705692A * 1996-09-27 1998-01-06 Abbott Laboratories Process for the preparation of iohexol
US5861140A * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Tripodal paramagnetic contrast agents for MR imaging
US5861138A * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Ligands for MRI contrast agent
GB9624612D0 * 1996-11-26 1997-01-15 Nycomed Imaging As Process
IT1286522B1 * 1996-12-04 1998-07-15 Dibra Spa Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico
IT1289520B1 * 1996-12-24 1998-10-15 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
IT1289521B1 * 1996-12-24 1998-10-15 Zambon Spa Processo per la purificazione di un intermedio
IT1289519B1 * 1996-12-24 1998-10-15 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
KR100758741B1 * 1997-02-11 2007-09-14 브라코 인터내셔날 비이.브이. 선형 또는 분지형 (ｃ5-ｃ6) 알콜 또는 그의 혼합물로부터 (ｓ)-ｎ,ｎ'-비스[2-히드록시-1-(히드록시메틸)에틸]-5-[(2-히드록시-1-옥소프로필)아미노]-2,4,6-트리요오도-1,3-벤젠디카르복스아미드의 결정화 방법
IT1292037B1 * 1997-05-30 1999-01-25 Bracco Spa Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
US5824288A * 1997-08-21 1998-10-20 Hoechst Celanese Corporation Thio-substituted pyridines as MRI ligand precursors
US5858329A * 1997-08-21 1999-01-12 Hoechst Celanese Corporation MRI diagnostic procedures using tripodal pyridinyl metal complexes
US5869026A * 1997-08-21 1999-02-09 Hoechst Celanese Corp. Tripodal carboxamide ligands for MRI contrast agents
US5820851A * 1997-08-21 1998-10-13 Hoechst Celanese Corporation Tripodal pyridine ligands as MRI contrast agents
US5869025A * 1997-08-21 1999-02-09 Hoechst Celanese Corporation Tripodal aromatic heterocycle carboxamide MRI contrast agents
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IT1302200B1 * 1998-09-11 2000-07-31 Dibra Spa PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1-
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Priority And Related Applications

Applications Claiming Priority (1)

Application Filing date Title
CH1658874A 1974-12-13

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