BE798403A - Esters basiques d'acides 1,4-dihydropyridine-carboxyliques et leur obtention - Google Patents

Esters basiques d'acides 1,4-dihydropyridine-carboxyliques et leur obtention

Info

Publication number
BE798403A
BE798403A BE130166A BE130166A BE798403A BE 798403 A BE798403 A BE 798403A BE 130166 A BE130166 A BE 130166A BE 130166 A BE130166 A BE 130166A BE 798403 A BE798403 A BE 798403A
Authority
BE
Belgium
Prior art keywords
dihydropyridine
obtaining
carboxylic acids
basic esters
esters
Prior art date
Application number
BE130166A
Other languages
English (en)
French (fr)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE798403A publication Critical patent/BE798403A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
BE130166A 1972-04-18 1973-04-18 Esters basiques d'acides 1,4-dihydropyridine-carboxyliques et leur obtention BE798403A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2218644A DE2218644C3 (de) 1972-04-18 1972-04-18 Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
BE798403A true BE798403A (fr) 1973-10-18

Family

ID=5842285

Family Applications (1)

Application Number Title Priority Date Filing Date
BE130166A BE798403A (fr) 1972-04-18 1973-04-18 Esters basiques d'acides 1,4-dihydropyridine-carboxyliques et leur obtention

Country Status (22)

Country Link
US (1) US3905970A (he)
JP (2) JPS4914614A (he)
AT (7) ATA45775A (he)
AU (1) AU467406B2 (he)
BE (1) BE798403A (he)
CA (1) CA1006515A (he)
CH (6) CH591445A5 (he)
CS (6) CS174248B2 (he)
DD (1) DD107275A5 (he)
DE (1) DE2218644C3 (he)
DK (1) DK137753C (he)
ES (1) ES413809A1 (he)
FI (1) FI55997C (he)
FR (1) FR2182983B1 (he)
GB (1) GB1383625A (he)
HU (1) HU167989B (he)
IE (1) IE37538B1 (he)
IL (1) IL42044A (he)
NL (1) NL176942C (he)
SE (1) SE398876B (he)
SU (6) SU518127A3 (he)
ZA (1) ZA732633B (he)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038399A (en) * 1972-04-18 1977-07-26 Bayer Aktiengesellschaft 1,4-dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives
FR2218107A1 (en) * 1973-02-20 1974-09-13 Yamanouchi Pharma Co Ltd Amino alkyl 2,6-dialkyl-4-aryl-1,4 dihydropyridine-3, carboxylates - useful as cerebral vasodilators and musculotropic spasmolytic agents
US3985758A (en) * 1973-02-20 1976-10-12 Yamanouchi Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2738153A1 (de) * 1977-08-24 1979-03-08 Bayer Ag 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2847237A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Verfahren zur herstellung von 1,4-dihydropyridincarbonsaeuren sowie ihre verwendung als arzneimittel
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
JPS57171968A (en) * 1981-04-17 1982-10-22 Kyowa Hakko Kogyo Co Ltd 1,4-dihydropyridine derivative
JPS57200386A (en) * 1981-06-04 1982-12-08 Yoshitomi Pharmaceut Ind Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
GB2108108B (en) * 1981-08-12 1985-08-07 Tokyo Tanabe Co Novel 1 4-dihydropyridine derivatives
JPS58131982A (ja) * 1982-02-01 1983-08-06 Tokyo Tanabe Co Ltd 新規なる1.4−ジヒドロピリジン誘導体
JPS58159490A (ja) * 1982-02-23 1983-09-21 Nikken Kagaku Kk 1,4−ジヒドロピリジン化合物
WO1983003249A1 (en) * 1982-03-17 1983-09-29 Yoshitomi Pharmaceutical 1,4-dihydropyridine-3,5-dicarboxylate derivatives
JPS58201765A (ja) * 1982-05-10 1983-11-24 Takeda Chem Ind Ltd ジヒドロピリジン誘導体,その製造法および用途
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
DE3377352D1 (en) * 1982-06-03 1988-08-18 Pierrel Spa Dihydropyridines with an antagonistic activity to calcium, process for their preparation, and pharmaceutical compositions containing them
US4419518A (en) * 1982-07-26 1983-12-06 Tokyo Tanabe Co. L.T.D. 1,4-Dihydropyridine derivatives
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
JPS5951281A (ja) * 1982-09-17 1984-03-24 Yoshitomi Pharmaceut Ind Ltd 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体
DE3234684A1 (de) * 1982-09-18 1984-03-22 Bayer Ag, 5090 Leverkusen Neue dihydropyrimidine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
JPS5970667A (ja) * 1982-10-15 1984-04-21 Kyowa Hakko Kogyo Co Ltd 1,4−ジヒドロピリジン誘導体
JPS5970666A (ja) * 1982-10-15 1984-04-21 Kyowa Hakko Kogyo Co Ltd 1,4−ジヒドロピリジン誘導体
DE3382204D1 (de) * 1982-10-15 1991-04-18 Kyowa Hakko Kogyo Kk 1,4-dihydropyridin-derivate.
JPS59225162A (ja) * 1983-06-03 1984-12-18 Kyowa Hakko Kogyo Co Ltd 1,4−ジヒドロピリジン誘導体
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
US4491582A (en) * 1983-03-03 1985-01-01 Usv Pharmaceutical Corporation N-(substituted piperazino)-1,4-dihydropyridine-3,5-carboxylic acid
AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
US4603135A (en) * 1983-10-17 1986-07-29 Takeda Chemical Industries, Ltd. Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates
JPS6092266A (ja) * 1983-10-27 1985-05-23 Teijin Ltd 1,4−ジヒドロピリジン−3,5−ジカルボン酸ジエステル誘導体,その製造法及びそれを有効成分とする薬剤
JPS60120861A (ja) * 1983-12-02 1985-06-28 Otsuka Pharmaceut Co Ltd ジヒドロピリジン誘導体
DE4342196A1 (de) * 1993-12-10 1995-06-14 Bayer Ag Neue 4-Phenyl-substituierte 1,4-Dihydropyridine
JPS60156671A (ja) * 1984-01-25 1985-08-16 Yamanouchi Pharmaceut Co Ltd ジヒドロピリジン誘導体およびその製造法
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
US4895846A (en) * 1984-04-11 1990-01-23 Bristol-Myers Company Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moieties
US4755512A (en) * 1984-04-11 1988-07-05 Bristol-Myers Company Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities
KR890004904B1 (ko) * 1984-08-03 1989-11-30 미쓰이 붓상 가부시기 가이샤 식품의 동결 방법 및 그 장치
JPS6147477A (ja) * 1984-08-14 1986-03-07 Kowa Co 新規1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体
JPH0676405B2 (ja) * 1986-06-13 1994-09-28 日清製粉株式会社 1,4―ジヒドロピリジン誘導体およびそれを含有する医薬組成物
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
US4833150A (en) * 1985-03-14 1989-05-23 Nelson Research & Development Co. 1,4-dihydropyridines
US4652573A (en) * 1985-03-14 1987-03-24 Nelson Research & Development Co. Calcium antagonist N-hetero ester 1,4-dihydropyridines
US4593033A (en) * 1985-04-24 1986-06-03 Merck & Co., Inc. Substituted indeno[2,1-c] pyridines useful as calcium channel blockers
DK8602336A (he) * 1985-05-21 1986-11-22
US4605660A (en) * 1985-06-03 1986-08-12 Merck & Co., Inc. Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers
US4670443A (en) * 1985-07-02 1987-06-02 Merck & Co., Inc. Benzo(f)isoquinoline compounds useful as calcium entry blockers
US4735956A (en) * 1985-09-13 1988-04-05 Merck & Co., Inc. Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers
DE3682857D1 (en) * 1985-09-13 1992-01-23 Green Cross Corp Dihydropyridinderivate.
IT1201476B (it) * 1985-10-04 1989-02-02 Yason Srl Derivato diidropiridinico,procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
US4721708A (en) * 1985-11-26 1988-01-26 Merck & Co., Inc. Cyclized N-substituted-tetrahydropyridine compounds and cardiovascular use
US4788203A (en) * 1985-11-26 1988-11-29 Merck & Co., Inc. Cyclized N-substituted-tetrahydropyridine compounds, useful in the treatment of cardiovascular disorders
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
US4849436A (en) * 1986-03-11 1989-07-18 Nelson Research & Development Co. 1,4-dihydropyridines
HU196755B (en) * 1986-09-16 1989-01-30 Gyogyszerkutato Intezet Process for production of new substituated amilid derivatives and medical compositions containing them
EP0394243A1 (de) * 1987-05-22 1990-10-31 Byk Gulden Lomberg Chemische Fabrik GmbH Verfahren zur herstellung von carbonsäuren
DE3732380A1 (de) * 1987-09-25 1989-04-06 Bayer Ag Dihydropyridinether, verfahren zu ihrer herstellung und ihre verwendung
EP0330470A3 (en) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. 1,4-dihydropyridine derivatives useful against tumour cells
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
EP0359377B1 (en) * 1988-07-28 1993-10-13 Nikken Chemicals Co., Ltd. 1,4-dihydropyridine derivative
DE4342195A1 (de) * 1993-12-10 1995-06-14 Bayer Ag Dihydropyridine mit heterocyclisch substituierten Estern

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545873A1 (de) * 1965-11-10 1970-02-26 Bayer Ag Verfahren zur Herstellung von Dihydrodipyridylderivaten
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE1963185A1 (de) * 1969-12-17 1971-06-24 Bayer Ag Neue Nitrophenyl-1,4-dihydropyridinderivate
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
IE37538B1 (en) 1977-08-17
ATA337373A (de) 1975-04-15
SU513620A3 (ru) 1976-05-05
CS174250B2 (he) 1977-03-31
DE2218644B2 (de) 1980-04-30
ZA732633B (en) 1974-03-27
ES413809A1 (es) 1976-01-16
AU5449173A (en) 1974-10-17
AT329560B (de) 1976-05-25
DD107275A5 (he) 1974-07-20
CH591446A5 (he) 1977-09-15
CH591445A5 (he) 1977-09-15
SU516352A3 (ru) 1976-05-30
CH590842A5 (he) 1977-08-31
ATA45775A (de) 1975-05-15
SU518127A3 (ru) 1976-06-15
CS174246B2 (he) 1977-03-31
CH590841A5 (he) 1977-08-31
FR2182983A1 (he) 1973-12-14
CS174248B2 (he) 1977-03-31
DE2218644A1 (de) 1973-10-25
HU167989B (he) 1976-02-28
GB1383625A (en) 1974-02-12
FI55997C (fi) 1979-11-12
JPS5024277A (he) 1975-03-15
DE2218644C3 (de) 1982-08-19
NL7305479A (he) 1973-10-22
ATA45875A (de) 1975-08-15
AT329559B (de) 1976-05-25
CS174249B2 (he) 1977-03-31
DK137753C (da) 1978-10-09
IL42044A0 (en) 1973-06-29
IE37538L (en) 1973-10-18
JPS4914614A (he) 1974-02-08
CA1006515A (en) 1977-03-08
SU513621A3 (ru) 1976-05-05
CS174201B2 (he) 1977-03-31
AU467406B2 (en) 1975-11-27
DK137753B (da) 1978-05-01
CS174247B2 (he) 1977-03-31
FI55997B (fi) 1979-07-31
IL42044A (en) 1976-09-30
FR2182983B1 (he) 1976-12-03
SU516351A3 (ru) 1976-05-30
CH588464A5 (he) 1977-06-15
NL176942B (nl) 1985-02-01
ATA45975A (de) 1975-08-15
NL176942C (nl) 1985-07-01
SU515452A3 (ru) 1976-05-25
CH589627A5 (he) 1977-07-15
US3905970A (en) 1975-09-16
AT327905B (de) 1976-02-25
SE398876B (sv) 1978-01-23
JPS5637225B2 (he) 1981-08-29
AT327191B (de) 1976-01-26

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: BAYER A.G.

Effective date: 19930418