AU775947B2 - Process for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives thereof, and salts thereof - Google Patents

Process for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives thereof, and salts thereof Download PDF

Info

Publication number
AU775947B2
AU775947B2 AU27662/00A AU2766200A AU775947B2 AU 775947 B2 AU775947 B2 AU 775947B2 AU 27662/00 A AU27662/00 A AU 27662/00A AU 2766200 A AU2766200 A AU 2766200A AU 775947 B2 AU775947 B2 AU 775947B2
Authority
AU
Australia
Prior art keywords
alkyl
compound
formula
phenyl
aminopyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27662/00A
Other languages
English (en)
Other versions
AU2766200A (en
Inventor
Tamim Fehme Braish
Stephane Caron
Michael James Castaldi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of AU2766200A publication Critical patent/AU2766200A/en
Application granted granted Critical
Publication of AU775947B2 publication Critical patent/AU775947B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU27662/00A 1999-05-17 2000-04-11 Process for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives thereof, and salts thereof Ceased AU775947B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13455999P 1999-05-17 1999-05-17
US60/134559 1999-05-17

Publications (2)

Publication Number Publication Date
AU2766200A AU2766200A (en) 2000-11-23
AU775947B2 true AU775947B2 (en) 2004-08-19

Family

ID=22463902

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27662/00A Ceased AU775947B2 (en) 1999-05-17 2000-04-11 Process for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives thereof, and salts thereof

Country Status (25)

Country Link
US (1) US6316632B1 (enExample)
EP (1) EP1054002B1 (enExample)
JP (1) JP3837011B2 (enExample)
KR (1) KR100386226B1 (enExample)
CN (1) CN1216865C (enExample)
AR (1) AR020029A1 (enExample)
AT (1) ATE306474T1 (enExample)
AU (1) AU775947B2 (enExample)
BR (1) BR0001773A (enExample)
CA (1) CA2308817C (enExample)
CZ (1) CZ299474B6 (enExample)
DE (1) DE60023063T2 (enExample)
DK (1) DK1054002T3 (enExample)
ES (1) ES2248017T3 (enExample)
HU (1) HUP0001928A3 (enExample)
ID (1) ID26061A (enExample)
IL (1) IL136105A (enExample)
IN (1) IN192341B (enExample)
MX (1) MXPA00004790A (enExample)
PL (1) PL198153B1 (enExample)
RS (1) RS49964B (enExample)
RU (1) RU2181120C2 (enExample)
TR (1) TR200001403A2 (enExample)
TW (1) TWI286133B (enExample)
ZA (1) ZA200002375B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4058433A1 (en) 2019-11-15 2022-09-21 KaNDy Therapeutics Limited New chemical process for making 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine a key intermediate of nt-814

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
JPH0794439B2 (ja) * 1990-05-31 1995-10-11 フアイザー・インコーポレイテツド 置換ピペリジンの製造法
AU647592B2 (en) 1991-03-26 1994-03-24 Pfizer Inc. Stereoselective preparation of substituted piperidines
SK282203B6 (sk) 1991-06-20 2001-12-03 Pfizer Inc. Fluoroalkoxybenzylamínové deriváty heterocyklov obsahujúcich dusík, spôsob ich prípravy, medziprodukty, spôsob prípravy medziproduktov, použitie a farmaceutický prostriedok
JP3042894B2 (ja) 1995-07-07 2000-05-22 ファイザー製薬株式会社 サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
TW340842B (en) 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
WO1998024447A1 (en) 1996-12-02 1998-06-11 Merck Sharp & Dohme Limited Use of nk-1 receptor antagonists for treating cognitive disorders
TW426667B (en) 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
STANFORTH P. TETRAHEDRON, 1998, 54, 263-303 *
ZHANG & CHAN TETRAHEDRON LETT. 1996, 37(3) 1043-1044 *

Also Published As

Publication number Publication date
RU2181120C2 (ru) 2002-04-10
JP3837011B2 (ja) 2006-10-25
MXPA00004790A (es) 2002-03-08
AR020029A1 (es) 2002-03-27
CA2308817C (en) 2005-06-14
CN1216865C (zh) 2005-08-31
JP2000355584A (ja) 2000-12-26
DE60023063D1 (de) 2006-02-23
PL198153B1 (pl) 2008-05-30
ID26061A (id) 2000-11-23
US6316632B1 (en) 2001-11-13
BR0001773A (pt) 2001-01-02
CZ20001800A3 (cs) 2001-03-14
EP1054002A1 (en) 2000-11-22
IL136105A (en) 2006-07-05
CN1288005A (zh) 2001-03-21
ATE306474T1 (de) 2005-10-15
ZA200002375B (en) 2001-11-15
PL340157A1 (en) 2000-11-20
KR100386226B1 (ko) 2003-06-02
HUP0001928A2 (en) 2001-03-28
CZ299474B6 (cs) 2008-08-06
TWI286133B (en) 2007-09-01
HU0001928D0 (en) 2000-07-28
RS49964B (sr) 2008-09-29
HUP0001928A3 (en) 2002-05-28
AU2766200A (en) 2000-11-23
EP1054002B1 (en) 2005-10-12
IN192341B (enExample) 2004-04-10
ES2248017T3 (es) 2006-03-16
KR20010020845A (ko) 2001-03-15
HK1032397A1 (en) 2001-07-20
CA2308817A1 (en) 2000-11-17
TR200001403A2 (tr) 2000-12-21
IL136105A0 (en) 2001-05-20
YU19600A (sh) 2002-03-18
DK1054002T3 (da) 2006-02-20
DE60023063T2 (de) 2006-04-20

Similar Documents

Publication Publication Date Title
TWI312782B (en) Pyrrolo-triazine aniline compounds useful as kinase inhibitors
CN105814060B (zh) 用作tnf活性调节剂的咪唑并三嗪衍生物
CN105814045B (zh) 作为tnf活性调节剂的咪唑并吡啶衍生物
CN105814053B (zh) 作为tnf活性调节剂的咪唑并吡啶衍生物
FI78691C (fi) Foerfarande foer framstaellning av i position 3-substituerade pyridazinderivat, vilka inverkar pao det centrala nervsystemet.
CZ287613B6 (en) Pyrazolo- and pyrrolopyridines and pharmaceutical preparations based thereon
CN105814025A (zh) 用作tnf活性调节剂的四氢苯并咪唑衍生物
CZ285799B6 (cs) Indolové deriváty, způsob jejich výroby, jejich použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
CN105814065A (zh) 用作tnf活性调节剂的咪唑并噻唑衍生物
AU2241400A (en) Novel thiazolobenzoimidazole derivative
RU2162470C2 (ru) 2,7-замещенные производные октагидропирроло[1,2-а]пиразина, способ лечения, фармацевтическая композиция, промежуточные соединения
DE69528189T2 (de) Diazepinoindole inhibitoren von phosphodiesterase iv
EP1054002B1 (en) Process for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives thereof, and salts thereof
CA2215020C (en) Tetrazolyl-substituted quinuclidines as substance p antagonists
WO2001014385A1 (en) Dihydrobenzofuran derivatives, process for the preparation thereof and agents
JP2003183283A (ja) 縮合インドール化合物、その製造法および用途
CN102741261A (zh) 新的氨基酸衍生物、其制备方法及其作为由Met家族引起的致癌信号的抑制剂的治疗用途
HK1032397B (en) Process for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives thereof, and salts thereof
MXPA99010622A (en) 3-substituted 3,4 dihydro-thieno[2, 3-d]pyrimidine derivatives and production and use of the same
IE47977B1 (en) 6,7-di(loweralkoxy)-4-amino-2-(substituted piperidino)quinazolines