AU713635B2 - Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix - Google Patents
Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix Download PDFInfo
- Publication number
- AU713635B2 AU713635B2 AU18180/97A AU1818097A AU713635B2 AU 713635 B2 AU713635 B2 AU 713635B2 AU 18180/97 A AU18180/97 A AU 18180/97A AU 1818097 A AU1818097 A AU 1818097A AU 713635 B2 AU713635 B2 AU 713635B2
- Authority
- AU
- Australia
- Prior art keywords
- chohch
- ligand
- anion
- anion exchanger
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/04—Processes using organic exchangers
- B01J41/07—Processes using organic exchangers in the weakly basic form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9600590A SE9600590D0 (sv) | 1996-02-19 | 1996-02-19 | Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris |
| SE9600590 | 1996-02-19 | ||
| PCT/SE1997/000237 WO1997029825A1 (en) | 1996-02-19 | 1997-02-14 | Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1818097A AU1818097A (en) | 1997-09-02 |
| AU713635B2 true AU713635B2 (en) | 1999-12-09 |
Family
ID=20401430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU18180/97A Ceased AU713635B2 (en) | 1996-02-19 | 1997-02-14 | Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6090288A (enExample) |
| EP (1) | EP0888157B1 (enExample) |
| JP (1) | JP4422797B2 (enExample) |
| AT (1) | ATE267037T1 (enExample) |
| AU (1) | AU713635B2 (enExample) |
| DE (1) | DE69729182T2 (enExample) |
| SE (1) | SE9600590D0 (enExample) |
| WO (1) | WO1997029825A1 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9425138D0 (en) * | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| KR100463475B1 (ko) | 1995-06-08 | 2005-06-22 | 로셰 디아그노스틱스 게엠베하 | 자기성피그먼트 |
| DE19520398B4 (de) | 1995-06-08 | 2009-04-16 | Roche Diagnostics Gmbh | Magnetisches Pigment |
| US6027945A (en) | 1997-01-21 | 2000-02-22 | Promega Corporation | Methods of isolating biological target materials using silica magnetic particles |
| SE9700769D0 (sv) | 1997-03-04 | 1997-03-04 | Pharmacia Biotech Ab | Matriser för separation och separation som utnyttjar matriserna |
| DE19736366A1 (de) * | 1997-08-21 | 1999-02-25 | Ernst Prof Dr Bayer | Verfahren zur Isolierung von anionischen organischen Verbindungen aus wäßrigen Systemen mit kationischen Polymernanopartikeln |
| KR20010032806A (ko) * | 1997-12-06 | 2001-04-25 | 매튜 존 베이커 | 핵산 분리방법 |
| US6914137B2 (en) * | 1997-12-06 | 2005-07-05 | Dna Research Innovations Limited | Isolation of nucleic acids |
| US7078224B1 (en) | 1999-05-14 | 2006-07-18 | Promega Corporation | Cell concentration and lysate clearance using paramagnetic particles |
| SE9802214D0 (sv) * | 1998-06-18 | 1998-06-18 | Amersham Pharm Biotech Ab | Jonbytare och användning därav |
| US6441152B1 (en) * | 1998-12-08 | 2002-08-27 | Boston Probes, Inc. | Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices |
| AU2862100A (en) * | 1999-01-27 | 2000-08-18 | Folim G. Halaka | Materials and methods for the purification of polyelectrolytes |
| US6310199B1 (en) | 1999-05-14 | 2001-10-30 | Promega Corporation | pH dependent ion exchange matrix and method of use in the isolation of nucleic acids |
| US6270970B1 (en) | 1999-05-14 | 2001-08-07 | Promega Corporation | Mixed-bed solid phase and its use in the isolation of nucleic acids |
| SE9904197D0 (sv) * | 1999-11-22 | 1999-11-22 | Amersham Pharm Biotech Ab | A method for anion exchange adsorption on matrices carrying mixed mode ligands |
| SE9904272D0 (sv) * | 1999-11-25 | 1999-11-25 | Amersham Pharm Biotech Ab | A method for selective removal of a substance from samples containing compounds having nucleic acid structure |
| GB9927904D0 (en) * | 1999-11-25 | 2000-01-26 | Amersham Pharm Biotech Ab | A method fro obtaining a nucleic acid variant |
| DK1257562T3 (da) * | 2000-02-08 | 2007-04-02 | Upfront Chromatography As | Hidtil ukendte harpiksmaterialer og anvendelsen deraf til isolering af proteiner eller peptider |
| US20020194901A1 (en) * | 2000-12-19 | 2002-12-26 | Showa Denko K.K. | Porous polymer particle, alkali-resistant anion exchanger, producing method thereof, column for ion chromatography, and method for measuring anions |
| US20030066336A1 (en) * | 2000-12-19 | 2003-04-10 | Showa Denko K.K. | Method for measuring anions |
| SE0004932D0 (sv) * | 2000-12-31 | 2000-12-31 | Apbiotech Ab | A method for mixed mode adsorption and mixed mode adsorbents |
| DE60202240T2 (de) * | 2001-05-21 | 2005-12-15 | Fuji Photo Film Co., Ltd., Minami-Ashigara | Vorrichtung zur Durchführung biochemischer Analysen und Verfahren zu ihrer Herstellung |
| SE0103084D0 (sv) * | 2001-09-14 | 2001-09-14 | Amersham Pharm Biotech Ab | Generation of ion exchange media |
| GB0127809D0 (en) * | 2001-11-20 | 2002-01-09 | Dna Res Innovations Ltd | Purification of nucleic acid |
| CA2473376A1 (en) | 2002-01-16 | 2003-07-31 | Invitrogen Dynal As | Method for isolating nucleic acids and protein from a single sample |
| WO2003074571A2 (en) * | 2002-02-28 | 2003-09-12 | Keck Graduate Institute | Cationic polyelectrolytes in biomolecule purification and analysis |
| US20060035224A1 (en) * | 2002-03-21 | 2006-02-16 | Johansen Jack T | Purification methods for oligonucleotides and their analogs |
| GB0207975D0 (en) * | 2002-04-05 | 2002-05-15 | Genovision As | Isolating nucleic acid |
| GB0212826D0 (en) * | 2002-05-31 | 2002-07-10 | Dna Res Innovations Ltd | Materials and methods relating to polyions and substance delivery |
| US6989442B2 (en) * | 2002-07-12 | 2006-01-24 | Sirna Therapeutics, Inc. | Deprotection and purification of oligonucleotides and their derivatives |
| WO2004078349A1 (en) * | 2003-03-05 | 2004-09-16 | Amersham Biosciences Ab | A method of preparing multi-modal anion-exchange ligands |
| SE0302911D0 (sv) * | 2003-10-31 | 2003-10-31 | Amersham Biosciences Ab | Novel separation matrix |
| US20050106589A1 (en) * | 2003-11-17 | 2005-05-19 | Hashem Akhavan-Tafti | Compositions and methods for releasing nucleic acids from solid phase binding materials |
| SE0303532D0 (sv) * | 2003-12-23 | 2003-12-23 | Amersham Biosciences Ab | Purification of immunoglobulins |
| US7479222B2 (en) * | 2004-02-05 | 2009-01-20 | Millipore Corporation | Porous adsorptive or chromatographic media |
| EP1693108A1 (en) * | 2004-12-04 | 2006-08-23 | MERCK PATENT GmbH | Mixed-modal anion-exchange type separation material |
| KR100668337B1 (ko) | 2005-05-21 | 2007-01-12 | 삼성전자주식회사 | 단백질에 비하여 핵산에 대한 결합력이 선택적으로 높은pH 의존성 이온 교환물질, 그가 고정화되어 있는 고체기판, 및 상기 물질 및 고체 기판을 이용하여 핵산을분리하는 방법 |
| EP1754534A1 (de) | 2005-08-03 | 2007-02-21 | MERCK PATENT GmbH | Hydrophiles vernetztes Polymer |
| WO2007014591A1 (de) | 2005-08-03 | 2007-02-08 | Merck Patent Gmbh | Hydrophiles vernetztes polymer |
| GB2443505B (en) | 2006-09-26 | 2008-12-31 | Ge Healthcare Bio Sciences | Nucleic acid purification method |
| GB2445441B (en) | 2006-09-26 | 2010-06-30 | Ge Healthcare Bio Sciences | Nucleic acid purification method |
| GB2445442A (en) * | 2006-09-26 | 2008-07-09 | Ge Healthcare Bio Sciences | Nucleic acid purification using anion exchange |
| US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
| DE202008017854U1 (de) | 2007-08-14 | 2010-08-19 | Millipore Corp., Billerica | Mittel zur Ionenaustausch-Membranchromatographie auf der Basis von primären polymerischen Aminen, Sorptionsvorrichtung mit diesem Mittel, Chromatographieverfahren und Reinigungsverfahren unter dessen Verwendung |
| US20090130738A1 (en) * | 2007-11-19 | 2009-05-21 | Mikhail Kozlov | Media for membrane ion exchange chromatography |
| EP2250182B1 (en) * | 2008-02-07 | 2015-12-02 | GE Healthcare Bio-Sciences Corp. | Isolation of dna, rna and protein from a single sample |
| JP5999899B2 (ja) | 2008-04-08 | 2016-09-28 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | 抗体のクロマトグラフィー精製法 |
| US20110065900A1 (en) * | 2008-05-30 | 2011-03-17 | Ge Healthcare Bio-Science Ab | Separation method utilizing polyallylamine ligands |
| CN103348242B (zh) | 2011-01-12 | 2016-08-17 | 积水医疗株式会社 | 单核苷酸多态性的检测方法 |
| US9481881B2 (en) | 2011-01-12 | 2016-11-01 | Sekisui Medical Co., Ltd. | Eluent for ion-exchange chromatography, and method of analyzing nucleic acid chains |
| KR102088639B1 (ko) * | 2011-02-10 | 2020-03-16 | 세키스이 메디칼 가부시키가이샤 | 이온 교환 크로마토그래피용 충전제 및 핵산 사슬의 분리 검출 방법 |
| WO2013134251A2 (en) | 2012-03-08 | 2013-09-12 | Bio-Rad Laboratories, Inc. | Anionic exchange-hydrophobic mixed mode |
| US9169304B2 (en) | 2012-05-01 | 2015-10-27 | Pfenex Inc. | Process for purifying recombinant Plasmodium falciparum circumsporozoite protein |
| IN2015DN02055A (enExample) | 2012-09-17 | 2015-08-14 | Grace W R & Co | |
| MY195756A (en) * | 2012-09-17 | 2023-02-09 | Grace W R & Co | Functionalized Particulate Support Material and Methods of Making and Using the Same |
| WO2014084790A1 (en) * | 2012-11-29 | 2014-06-05 | Jerker Porath | Superhydroxylated adsorbents and uses thereof |
| EP3094390B1 (en) | 2014-01-16 | 2021-07-07 | W.R. Grace & CO. - CONN. | Affinity chromatography media and chromatography devices |
| CN106102903A (zh) * | 2014-03-14 | 2016-11-09 | 通用电气医疗集团生物工艺研发股份公司 | 用于生物颗粒纯化的分离基质 |
| EP3137209B1 (en) | 2014-05-02 | 2022-10-05 | W.R. Grace & CO. - CONN. | Functionalized support material and methods of making and using functionalized support material |
| SG11201609908VA (en) | 2014-05-28 | 2016-12-29 | Agency Science Tech & Res | Virus reduction method |
| US10526287B2 (en) | 2015-04-23 | 2020-01-07 | Constellation Pharmaceuticals, Inc. | LSD1 inhibitors and uses thereof |
| SG10201911134QA (en) | 2015-06-05 | 2020-01-30 | Grace W R & Co | Adsorbent bioprocessing clarification agents and methods of making and using the same |
| CN109715648A (zh) * | 2016-09-15 | 2019-05-03 | 克拉维格两合股份有限公司 | 聚合网状物用于大分子纯化的用途 |
| MD3532459T2 (ro) | 2016-10-26 | 2024-06-30 | Constellation Pharmaceuticals Inc | Inhibitori ai LSD1 și utilizările medicale ale acestora |
| CN110709696B (zh) * | 2017-06-22 | 2022-01-04 | 昭和电工株式会社 | 寡核苷酸的混合物的分离分析方法 |
| EP3749697A4 (en) | 2018-02-05 | 2021-11-03 | Bio-Rad Laboratories, Inc. | CHROMATOGRAPHY RESIN WITH LIGAND MIXED MODE ANIONIC / HYDROPHOBIC EXCHANGE |
| CN111818980B (zh) | 2018-03-08 | 2022-10-11 | 生物辐射实验室股份有限公司 | 阴离子交换-疏水混合模式色谱树脂 |
| US11896969B2 (en) | 2019-09-05 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Anionic exchange-hydrophobic mixed mode chromatography resins |
| CN114787622B (zh) | 2019-12-05 | 2025-03-25 | 沃特世科技公司 | 用于提高回收率并将系统损失减到最小的聚膦酸 |
| EP4182460A1 (en) * | 2020-07-14 | 2023-05-24 | Waters Technologies Corporation | Kits and methods useful for separating oligonucleotides from matrix components |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0276138A2 (en) * | 1987-01-21 | 1988-07-27 | E.I. Du Pont De Nemours And Company | Chromatographic supports for separation of oligonucleotides |
| EP0416748A1 (en) * | 1989-08-07 | 1991-03-13 | J.T. Baker Inc. | Quaternised pei silica solid supports for chromatography |
| WO1992011088A1 (en) * | 1990-12-21 | 1992-07-09 | Pharmacia Lkb Biotechnology Ab | Anion exchanger |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8902315D0 (sv) * | 1989-06-27 | 1989-06-27 | Pharmacia Ab | Anjonbytare |
| US5087359A (en) * | 1989-08-07 | 1992-02-11 | J. T. Baker Inc. | Quaternized PEI silica solid supports for chromatography |
-
1996
- 1996-02-19 SE SE9600590A patent/SE9600590D0/xx unknown
-
1997
- 1997-02-14 AU AU18180/97A patent/AU713635B2/en not_active Ceased
- 1997-02-14 EP EP97903706A patent/EP0888157B1/en not_active Expired - Lifetime
- 1997-02-14 DE DE69729182T patent/DE69729182T2/de not_active Expired - Lifetime
- 1997-02-14 US US09/117,678 patent/US6090288A/en not_active Expired - Lifetime
- 1997-02-14 WO PCT/SE1997/000237 patent/WO1997029825A1/en not_active Ceased
- 1997-02-14 JP JP52927797A patent/JP4422797B2/ja not_active Expired - Lifetime
- 1997-02-14 AT AT97903706T patent/ATE267037T1/de not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0276138A2 (en) * | 1987-01-21 | 1988-07-27 | E.I. Du Pont De Nemours And Company | Chromatographic supports for separation of oligonucleotides |
| EP0416748A1 (en) * | 1989-08-07 | 1991-03-13 | J.T. Baker Inc. | Quaternised pei silica solid supports for chromatography |
| WO1992011088A1 (en) * | 1990-12-21 | 1992-07-09 | Pharmacia Lkb Biotechnology Ab | Anion exchanger |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0888157A1 (en) | 1999-01-07 |
| ATE267037T1 (de) | 2004-06-15 |
| DE69729182T2 (de) | 2005-01-27 |
| WO1997029825A1 (en) | 1997-08-21 |
| DE69729182D1 (de) | 2004-06-24 |
| AU1818097A (en) | 1997-09-02 |
| JP4422797B2 (ja) | 2010-02-24 |
| EP0888157B1 (en) | 2004-05-19 |
| JP2000504625A (ja) | 2000-04-18 |
| SE9600590D0 (sv) | 1996-02-19 |
| US6090288A (en) | 2000-07-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0888157B1 (en) | Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix | |
| Alpert et al. | Preparation of a porous microparticulatee anion-exchange chromatography support for proteins | |
| JP5051957B2 (ja) | アニオン交換吸着方法およびアニオン交換体 | |
| EP1003599B1 (en) | An adsorption/separation method | |
| EP0464187A1 (en) | Coated media for chromatography | |
| JP2004516928A5 (enExample) | ||
| US5801237A (en) | Method for the purification of short nucleic acids | |
| JPS6225102A (ja) | 多孔性ポリサツカライドの架橋方法 | |
| EP0436684B1 (en) | Anion exchanger | |
| EP1345694B1 (en) | A method for the manufacture of compositions containing low concentrations of salts | |
| JP4044048B2 (ja) | エナンチオ選択的カチオン交換材料 | |
| KR20050105496A (ko) | 금속 킬레이트 친화성 리간드의 형성 방법 | |
| JP2004532182A5 (enExample) | ||
| JP4643006B2 (ja) | カチオン交換体による分離方法 | |
| US20050267295A1 (en) | Method for selective removal of a substance from samples containing compounds having nucleic acid structure | |
| JP2006523220A (ja) | マルチモードアニオン交換リガンドの製造法 | |
| CA2242927C (en) | Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix | |
| US7368561B2 (en) | Isolation of antisense oligonucleotides | |
| JPS60169427A (ja) | タンパク質の分離方法 | |
| EP1455920A1 (en) | Separation method | |
| KR20250078450A (ko) | 크로마토그래피 리간드 및 크로마토그래피 재료, 및 그의 용도 | |
| JPH08259497A (ja) | アニオン交換樹脂を用いたアナカルド酸の分離精製方法 | |
| EP1007201A1 (en) | Chromatography materials, a process for their preparation and use of the materials | |
| Outumuro et al. | Preparation and characterization of macromolecular dyes obtained by copolymerization of new acrylic derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |