SE9600590D0 - Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris - Google Patents

Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris

Info

Publication number
SE9600590D0
SE9600590D0 SE9600590A SE9600590A SE9600590D0 SE 9600590 D0 SE9600590 D0 SE 9600590D0 SE 9600590 A SE9600590 A SE 9600590A SE 9600590 A SE9600590 A SE 9600590A SE 9600590 D0 SE9600590 D0 SE 9600590D0
Authority
SE
Sweden
Prior art keywords
pct
nucleic acid
peptides
methods
ion exchange
Prior art date
Application number
SE9600590A
Other languages
English (en)
Swedish (sv)
Inventor
Rolf Henry Berglund
Jan Erik Alfons Bergstroem
Makonnen Belew
John Lennart Soederberg
Original Assignee
Pharmacia Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Biotech Ab filed Critical Pharmacia Biotech Ab
Priority to SE9600590A priority Critical patent/SE9600590D0/xx
Publication of SE9600590D0 publication Critical patent/SE9600590D0/xx
Priority to EP97903706A priority patent/EP0888157B1/en
Priority to AT97903706T priority patent/ATE267037T1/de
Priority to CA002242927A priority patent/CA2242927C/en
Priority to AU18180/97A priority patent/AU713635B2/en
Priority to DE69729182T priority patent/DE69729182T2/de
Priority to JP52927797A priority patent/JP4422797B2/ja
Priority to PCT/SE1997/000237 priority patent/WO1997029825A1/en
Priority to US09/117,678 priority patent/US6090288A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/04—Processes using organic exchangers
    • B01J41/07—Processes using organic exchangers in the weakly basic form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
SE9600590A 1996-02-19 1996-02-19 Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris SE9600590D0 (sv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE9600590A SE9600590D0 (sv) 1996-02-19 1996-02-19 Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris
EP97903706A EP0888157B1 (en) 1996-02-19 1997-02-14 Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix
AT97903706T ATE267037T1 (de) 1996-02-19 1997-02-14 Prozess zur chromatographischen trennung von peptiden und nucleinsaure und neue ionentauschermatrix mit hoher affinitat
CA002242927A CA2242927C (en) 1996-02-19 1997-02-14 Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix
AU18180/97A AU713635B2 (en) 1996-02-19 1997-02-14 Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix
DE69729182T DE69729182T2 (de) 1996-02-19 1997-02-14 Prozess zur chromatographischen trennung von peptiden und nucleinsaure und neue ionentauschermatrix mit hoher affinität
JP52927797A JP4422797B2 (ja) 1996-02-19 1997-02-14 ペプチドおよび核酸のクロマトグラフィー的分離法、ならびに新規な高アフィニティーイオン交換マトリクス
PCT/SE1997/000237 WO1997029825A1 (en) 1996-02-19 1997-02-14 Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix
US09/117,678 US6090288A (en) 1996-02-19 1997-02-14 Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9600590A SE9600590D0 (sv) 1996-02-19 1996-02-19 Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris

Publications (1)

Publication Number Publication Date
SE9600590D0 true SE9600590D0 (sv) 1996-02-19

Family

ID=20401430

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9600590A SE9600590D0 (sv) 1996-02-19 1996-02-19 Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris

Country Status (8)

Country Link
US (1) US6090288A (enExample)
EP (1) EP0888157B1 (enExample)
JP (1) JP4422797B2 (enExample)
AT (1) ATE267037T1 (enExample)
AU (1) AU713635B2 (enExample)
DE (1) DE69729182T2 (enExample)
SE (1) SE9600590D0 (enExample)
WO (1) WO1997029825A1 (enExample)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
DE19520398B4 (de) 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
KR100463475B1 (ko) 1995-06-08 2005-06-22 로셰 디아그노스틱스 게엠베하 자기성피그먼트
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
SE9700769D0 (sv) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
DE19736366A1 (de) * 1997-08-21 1999-02-25 Ernst Prof Dr Bayer Verfahren zur Isolierung von anionischen organischen Verbindungen aus wäßrigen Systemen mit kationischen Polymernanopartikeln
US6914137B2 (en) * 1997-12-06 2005-07-05 Dna Research Innovations Limited Isolation of nucleic acids
ES2177093T3 (es) * 1997-12-06 2002-12-01 Dna Res Innovations Ltd Aislamiento de acidos nucleicos.
US7078224B1 (en) 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
SE9802214D0 (sv) * 1998-06-18 1998-06-18 Amersham Pharm Biotech Ab Jonbytare och användning därav
WO2000034521A1 (en) * 1998-12-08 2000-06-15 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
WO2000044928A2 (en) * 1999-01-27 2000-08-03 Halaka Folim G Materials and methods for the purification of polyelectrolytes
US6270970B1 (en) 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
US6310199B1 (en) 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
SE9904197D0 (sv) * 1999-11-22 1999-11-22 Amersham Pharm Biotech Ab A method for anion exchange adsorption on matrices carrying mixed mode ligands
SE9904272D0 (sv) * 1999-11-25 1999-11-25 Amersham Pharm Biotech Ab A method for selective removal of a substance from samples containing compounds having nucleic acid structure
GB9927904D0 (en) * 1999-11-25 2000-01-26 Amersham Pharm Biotech Ab A method fro obtaining a nucleic acid variant
ATE346856T1 (de) * 2000-02-08 2006-12-15 Upfront Chromatography As Neue harze und ihre verwendung zur rückgewinnung von proteinen oder peptiden
US20030066336A1 (en) * 2000-12-19 2003-04-10 Showa Denko K.K. Method for measuring anions
US20020194901A1 (en) * 2000-12-19 2002-12-26 Showa Denko K.K. Porous polymer particle, alkali-resistant anion exchanger, producing method thereof, column for ion chromatography, and method for measuring anions
SE0004932D0 (sv) * 2000-12-31 2000-12-31 Apbiotech Ab A method for mixed mode adsorption and mixed mode adsorbents
EP1267169B1 (en) * 2001-05-21 2004-12-15 Fuji Photo Film Co., Ltd. Biochemical analysis unit and method for its production
SE0103084D0 (sv) * 2001-09-14 2001-09-14 Amersham Pharm Biotech Ab Generation of ion exchange media
GB0127809D0 (en) * 2001-11-20 2002-01-09 Dna Res Innovations Ltd Purification of nucleic acid
CN1617938A (zh) 2002-01-16 2005-05-18 戴诺生物技术有限公司 从单个样品中分离核酸和蛋白质的方法
AU2003217837A1 (en) * 2002-02-28 2003-09-16 Keck Graduate Institute Cationic polyelectrolytes in biomolecule purification and analysis
US20060035224A1 (en) * 2002-03-21 2006-02-16 Johansen Jack T Purification methods for oligonucleotides and their analogs
GB0207975D0 (en) * 2002-04-05 2002-05-15 Genovision As Isolating nucleic acid
GB0212826D0 (en) 2002-05-31 2002-07-10 Dna Res Innovations Ltd Materials and methods relating to polyions and substance delivery
US6989442B2 (en) * 2002-07-12 2006-01-24 Sirna Therapeutics, Inc. Deprotection and purification of oligonucleotides and their derivatives
DE602004018616D1 (de) 2003-03-05 2009-02-05 Ge Healthcare Bio Sciences Ab Verfahren zur herstellung von multimodalen anionenaustauschliganden
SE0302911D0 (sv) * 2003-10-31 2003-10-31 Amersham Biosciences Ab Novel separation matrix
US20050106589A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Compositions and methods for releasing nucleic acids from solid phase binding materials
SE0303532D0 (sv) * 2003-12-23 2003-12-23 Amersham Biosciences Ab Purification of immunoglobulins
US7479222B2 (en) * 2004-02-05 2009-01-20 Millipore Corporation Porous adsorptive or chromatographic media
EP1693108A1 (en) * 2004-12-04 2006-08-23 MERCK PATENT GmbH Mixed-modal anion-exchange type separation material
KR100668337B1 (ko) 2005-05-21 2007-01-12 삼성전자주식회사 단백질에 비하여 핵산에 대한 결합력이 선택적으로 높은pH 의존성 이온 교환물질, 그가 고정화되어 있는 고체기판, 및 상기 물질 및 고체 기판을 이용하여 핵산을분리하는 방법
CN101258175B (zh) 2005-08-03 2011-11-16 默克专利股份公司 亲水交联聚合物
EP1754534A1 (de) 2005-08-03 2007-02-21 MERCK PATENT GmbH Hydrophiles vernetztes Polymer
GB2445442A (en) * 2006-09-26 2008-07-09 Ge Healthcare Bio Sciences Nucleic acid purification using anion exchange
GB2443505B (en) * 2006-09-26 2008-12-31 Ge Healthcare Bio Sciences Nucleic acid purification method
GB2445441B (en) 2006-09-26 2010-06-30 Ge Healthcare Bio Sciences Nucleic acid purification method
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
DE202008017854U1 (de) 2007-08-14 2010-08-19 Millipore Corp., Billerica Mittel zur Ionenaustausch-Membranchromatographie auf der Basis von primären polymerischen Aminen, Sorptionsvorrichtung mit diesem Mittel, Chromatographieverfahren und Reinigungsverfahren unter dessen Verwendung
US20090130738A1 (en) * 2007-11-19 2009-05-21 Mikhail Kozlov Media for membrane ion exchange chromatography
WO2009100172A1 (en) 2008-02-07 2009-08-13 Ge Healthcare Bio-Sciences Corp. Isolation of dna, rna and protein from a single sample
WO2009126603A1 (en) 2008-04-08 2009-10-15 Bio-Rad Laboratories, Inc. Chromatography purification of antibodies
WO2009145722A1 (en) * 2008-05-30 2009-12-03 Ge Healthcare Bio-Sciences Ab Separation method utilizing polyallylamine ligands
JP6061381B2 (ja) 2011-01-12 2017-01-18 積水メディカル株式会社 一塩基多型の検出方法
JP6090985B2 (ja) * 2011-01-12 2017-03-08 積水メディカル株式会社 核酸鎖の分離方法
CN105911183B (zh) * 2011-02-10 2019-03-22 积水医疗株式会社 离子交换色谱法用填充剂以及核酸链的分离检测方法
CN104812491B (zh) 2012-03-08 2018-06-19 生物辐射实验室股份有限公司 阴离子交换-疏水性混合模式
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
MY195756A (en) * 2012-09-17 2023-02-09 Grace W R & Co Functionalized Particulate Support Material and Methods of Making and Using the Same
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
EP2925432A4 (en) * 2012-11-29 2016-08-31 Affigel Ab SUPER-HYDROXYLATED ADSORBENTS AND USES THEREOF
JP6853670B2 (ja) 2014-01-16 2021-04-07 ダブリュー・アール・グレース・アンド・カンパニー−コーンW R Grace & Co−Conn 親和性クロマトグラフィー媒体及びクロマトグラフィーデバイス
WO2015137860A1 (en) * 2014-03-14 2015-09-17 Ge Healthcare Bio-Sciences Ab Separation matrices for purification of biological particles
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンW R Grace & Co−Conn 官能化担体材料並びに官能化担体材料を作製及び使用する方法
SG11201609908VA (en) 2014-05-28 2016-12-29 Agency Science Tech & Res Virus reduction method
EP3286172B1 (en) 2015-04-23 2019-06-12 Constellation Pharmaceuticals, Inc. Lsd1 inhibitors and uses thereof
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
US11059856B2 (en) * 2016-09-15 2021-07-13 Klawego Gmbh & Co. Kg Use of a polymeric mesh for the purification of macromolecules
LT3532459T (lt) 2016-10-26 2023-11-10 Constellation Pharmaceuticals, Inc. Lsd1 inhibitoriai ir jų medicininis panaudojimas
EP3644055B1 (en) * 2017-06-22 2022-04-13 Showa Denko K.K. Separation/analysis method for mixture of oligonucleotides
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
CN111818980B (zh) 2018-03-08 2022-10-11 生物辐射实验室股份有限公司 阴离子交换-疏水混合模式色谱树脂
CN114040815B (zh) 2019-09-05 2024-06-28 生物辐射实验室股份有限公司 阴离子交换-疏水混合模式色谱树脂
WO2021111418A1 (en) 2019-12-05 2021-06-10 Waters Technologies Corporation Polyphosphonic acids for improving recovery and minimizing system loss
US20220017887A1 (en) * 2020-07-14 2022-01-20 Waters Technologies Corporation Compositions, kits and methods useful for separating oligonucleotides from matrix components

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767670A (en) * 1987-01-21 1988-08-30 E. I. Du Pont De Nemours And Company Chromatographic supports for separation of oligonucleotides
SE8902315D0 (sv) * 1989-06-27 1989-06-27 Pharmacia Ab Anjonbytare
US5087359A (en) * 1989-08-07 1992-02-11 J. T. Baker Inc. Quaternized PEI silica solid supports for chromatography
EP0416748B1 (en) * 1989-08-07 1994-03-30 J.T. Baker Inc. Quaternised pei silica solid supports for chromatography
SE9004129D0 (sv) * 1990-12-21 1990-12-21 Pharmacia Lkb Biotech Anion exchanger

Also Published As

Publication number Publication date
EP0888157A1 (en) 1999-01-07
DE69729182T2 (de) 2005-01-27
ATE267037T1 (de) 2004-06-15
DE69729182D1 (de) 2004-06-24
WO1997029825A1 (en) 1997-08-21
AU713635B2 (en) 1999-12-09
US6090288A (en) 2000-07-18
EP0888157B1 (en) 2004-05-19
JP2000504625A (ja) 2000-04-18
AU1818097A (en) 1997-09-02
JP4422797B2 (ja) 2010-02-24

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