AU684877B2 - Indoline derivatives, method of preparation and their use as pharmaceuticals - Google Patents
Indoline derivatives, method of preparation and their use as pharmaceuticals Download PDFInfo
- Publication number
- AU684877B2 AU684877B2 AU12743/95A AU1274395A AU684877B2 AU 684877 B2 AU684877 B2 AU 684877B2 AU 12743/95 A AU12743/95 A AU 12743/95A AU 1274395 A AU1274395 A AU 1274395A AU 684877 B2 AU684877 B2 AU 684877B2
- Authority
- AU
- Australia
- Prior art keywords
- formula
- compound
- compounds
- international
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939326192A GB9326192D0 (en) | 1993-12-22 | 1993-12-22 | Chemical compounds |
| GB9326192 | 1993-12-22 | ||
| PCT/EP1994/004220 WO1995017405A1 (en) | 1993-12-22 | 1994-12-20 | Indoline derivatives, method of preparation and their use as pharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1274395A AU1274395A (en) | 1995-07-10 |
| AU684877B2 true AU684877B2 (en) | 1998-01-08 |
Family
ID=10747030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU12743/95A Ceased AU684877B2 (en) | 1993-12-22 | 1994-12-20 | Indoline derivatives, method of preparation and their use as pharmaceuticals |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5633276A (online.php) |
| EP (1) | EP0736028A1 (online.php) |
| JP (1) | JPH09507057A (online.php) |
| AP (1) | AP535A (online.php) |
| AU (1) | AU684877B2 (online.php) |
| CA (1) | CA2179402A1 (online.php) |
| CO (1) | CO4340623A1 (online.php) |
| GB (1) | GB9326192D0 (online.php) |
| IL (1) | IL112097A (online.php) |
| IS (1) | IS4244A (online.php) |
| MY (1) | MY131641A (online.php) |
| SV (1) | SV1994000083A (online.php) |
| TW (1) | TW291479B (online.php) |
| WO (1) | WO1995017405A1 (online.php) |
| ZA (1) | ZA9410056B (online.php) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2741799B1 (fr) * | 1995-12-04 | 1998-01-02 | Oreal | Utilisation de melatonine dans une composition pour traiter les signes cutanes des etats de fatigue |
| US6034239A (en) * | 1996-03-08 | 2000-03-07 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| CA2241666C (en) * | 1996-03-08 | 2007-11-06 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| EP1199304A1 (en) * | 1997-03-05 | 2002-04-24 | Takeda Chemical Industries, Ltd. | Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders |
| RU2190609C2 (ru) * | 1996-12-10 | 2002-10-10 | Бристол-Маерс Сквибб Компани | Производные бензодиоксола, бензофурана, дигидробензофурана и бензодиоксана и содержащие их композиции |
| US5948817A (en) * | 1997-03-05 | 1999-09-07 | Bristol-Myers Squibb Company | Polycyclic ethyl alkylamide melatonergic agents |
| FR2763335B1 (fr) * | 1997-05-16 | 2000-11-24 | Adir | Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| AU727654B2 (en) * | 1997-06-13 | 2000-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Tricyclic pyrazole derivative |
| EP1082115A4 (en) * | 1998-06-05 | 2002-10-24 | Bristol Myers Squibb Co | MELATONERGICS BASED ON HETEROCYCLIC CIS DERIVATIVES OF CYCLOPROPANE |
| ES2213022T3 (es) | 1999-06-30 | 2004-08-16 | Bristol-Myers Squibb Company | Derivados de aminopirrolidina heterociclicos utiles como agentes melatonergicos. |
| GB9918965D0 (en) * | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxi |
| WO2001014385A1 (en) | 1999-08-20 | 2001-03-01 | Takeda Chemical Industries, Ltd. | Dihydrobenzofuran derivatives, process for the preparation thereof and agents |
| US7012090B1 (en) | 2000-03-17 | 2006-03-14 | Alcon, Inc. | Pyranoindoles for treating glaucoma |
| DK1268482T3 (da) * | 2000-03-17 | 2003-12-22 | Alcon Inc | Pyranoindoler til behandling af glaukom |
| ES2172415B2 (es) | 2000-07-28 | 2003-11-16 | Univ Madrid Complutense | Tratamiento del glaucoma y la hipertension ocular por medio de un analogo de la melatonina. |
| US6743448B2 (en) * | 2000-12-11 | 2004-06-01 | Abraham H. Kryger | Topical testosterone formulations and associated methods |
| US20030096379A1 (en) * | 2001-03-28 | 2003-05-22 | Kilgore James L. | Method for producing tryptamine derivatives |
| CA2644181A1 (en) * | 2006-03-20 | 2007-09-27 | Takeda Pharmaceutical Company Limited | Prophylactic or therapeutic agent for irritable bowel syndrome |
| WO2008069311A1 (ja) | 2006-12-08 | 2008-06-12 | Takeda Pharmaceutical Company Limited | 三環性化合物およびその医薬用途 |
| ES2331274B1 (es) * | 2007-10-25 | 2010-10-21 | Ferrer Internacional, S.A. | Compuesto de indolina. |
| MX2011001062A (es) * | 2008-07-30 | 2011-03-24 | Ferrer Int | Compuestos de 1,6-dihidro-2h-3-oxa-6-aza-as-indaceno. |
| BR102016024814A2 (pt) | 2016-10-24 | 2018-05-08 | Aché Laboratórios Farmacêuticos S.A. | composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0043752A1 (fr) * | 1980-06-26 | 1982-01-13 | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: | Dérivé de pyranno-indole et son procédé de préparation |
| EP0207605A1 (en) * | 1985-05-21 | 1987-01-07 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
-
1993
- 1993-12-22 GB GB939326192A patent/GB9326192D0/en active Pending
-
1994
- 1994-12-08 TW TW083111439A patent/TW291479B/zh active
- 1994-12-16 IS IS4244A patent/IS4244A/is unknown
- 1994-12-19 MY MYPI94003410A patent/MY131641A/en unknown
- 1994-12-19 ZA ZA9410056A patent/ZA9410056B/xx unknown
- 1994-12-20 AP APAP/P/1994/000706A patent/AP535A/en active
- 1994-12-20 WO PCT/EP1994/004220 patent/WO1995017405A1/en not_active Ceased
- 1994-12-20 JP JP7517174A patent/JPH09507057A/ja active Pending
- 1994-12-20 US US08/652,460 patent/US5633276A/en not_active Expired - Fee Related
- 1994-12-20 CA CA002179402A patent/CA2179402A1/en not_active Abandoned
- 1994-12-20 AU AU12743/95A patent/AU684877B2/en not_active Ceased
- 1994-12-20 EP EP95903817A patent/EP0736028A1/en not_active Ceased
- 1994-12-21 SV SV1994000083A patent/SV1994000083A/es unknown
- 1994-12-21 IL IL112097A patent/IL112097A/en not_active IP Right Cessation
- 1994-12-21 CO CO94057739A patent/CO4340623A1/es unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0043752A1 (fr) * | 1980-06-26 | 1982-01-13 | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: | Dérivé de pyranno-indole et son procédé de préparation |
| EP0207605A1 (en) * | 1985-05-21 | 1987-01-07 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
Also Published As
| Publication number | Publication date |
|---|---|
| IL112097A (en) | 1998-06-15 |
| JPH09507057A (ja) | 1997-07-15 |
| IS4244A (is) | 1995-06-23 |
| AP9400706A0 (en) | 1995-01-31 |
| AP535A (en) | 1996-09-16 |
| WO1995017405A1 (en) | 1995-06-29 |
| SV1994000083A (es) | 1995-07-24 |
| EP0736028A1 (en) | 1996-10-09 |
| GB9326192D0 (en) | 1994-02-23 |
| TW291479B (online.php) | 1996-11-21 |
| MY131641A (en) | 2007-08-30 |
| AU1274395A (en) | 1995-07-10 |
| ZA9410056B (en) | 1995-10-18 |
| CA2179402A1 (en) | 1995-06-29 |
| US5633276A (en) | 1997-05-27 |
| IL112097A0 (en) | 1995-03-15 |
| CO4340623A1 (es) | 1996-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |