AU680629B2 - Method of obtaining 10-deacetylbaccatine III - Google Patents

Method of obtaining 10-deacetylbaccatine III Download PDF

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Publication number
AU680629B2
AU680629B2 AU51155/93A AU5115593A AU680629B2 AU 680629 B2 AU680629 B2 AU 680629B2 AU 51155/93 A AU51155/93 A AU 51155/93A AU 5115593 A AU5115593 A AU 5115593A AU 680629 B2 AU680629 B2 AU 680629B2
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AU
Australia
Prior art keywords
process according
butyl
ether
acetate
ethyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU51155/93A
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English (en)
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AU5115593A (en
Inventor
Jean-Claude Gaullier
Bernadette Mandard
Rodolphe Margraff
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Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
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Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of AU5115593A publication Critical patent/AU5115593A/en
Application granted granted Critical
Publication of AU680629B2 publication Critical patent/AU680629B2/en
Assigned to AVENTIS PHARMA S.A. reassignment AVENTIS PHARMA S.A. Request to Amend Deed and Register Assignors: RHONE-POULENC RORER S.A.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Fats And Perfumes (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU51155/93A 1992-10-05 1993-10-04 Method of obtaining 10-deacetylbaccatine III Expired AU680629B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9211746A FR2696463B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.
FR9211746 1992-10-05
PCT/FR1993/000972 WO1994007882A1 (fr) 1992-10-05 1993-10-04 Procede d'obtention de la desacetyl-10 baccatine iii

Publications (2)

Publication Number Publication Date
AU5115593A AU5115593A (en) 1994-04-26
AU680629B2 true AU680629B2 (en) 1997-08-07

Family

ID=9434124

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51155/93A Expired AU680629B2 (en) 1992-10-05 1993-10-04 Method of obtaining 10-deacetylbaccatine III

Country Status (30)

Country Link
US (1) US5393895A (esLanguage)
EP (1) EP0663910B1 (esLanguage)
JP (1) JP3299754B2 (esLanguage)
KR (1) KR100301236B1 (esLanguage)
CN (1) CN1043530C (esLanguage)
AT (1) ATE148883T1 (esLanguage)
AU (1) AU680629B2 (esLanguage)
CA (1) CA2146373C (esLanguage)
CZ (2) CZ284615B6 (esLanguage)
DE (1) DE69308155T2 (esLanguage)
DK (1) DK0663910T3 (esLanguage)
EE (1) EE03126B1 (esLanguage)
ES (1) ES2098061T3 (esLanguage)
FI (1) FI109794B (esLanguage)
FR (1) FR2696463B1 (esLanguage)
GE (1) GEP20001937B (esLanguage)
GR (1) GR3022617T3 (esLanguage)
HU (1) HU226862B1 (esLanguage)
LT (1) LT3398B (esLanguage)
LV (1) LV10621B (esLanguage)
MX (1) MX9305771A (esLanguage)
NO (1) NO310413B1 (esLanguage)
NZ (1) NZ256450A (esLanguage)
PL (1) PL177316B1 (esLanguage)
RU (1) RU2107065C1 (esLanguage)
SK (1) SK280949B6 (esLanguage)
TW (1) TW255890B (esLanguage)
UA (1) UA44227C2 (esLanguage)
WO (1) WO1994007882A1 (esLanguage)
ZA (1) ZA937313B (esLanguage)

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FR2696462B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
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FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
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FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5750736A (en) * 1996-07-11 1998-05-12 Napro Biotherapeutics, Inc. Method for acylating 10-deacetylbaccatin III selectively at the c-10 position
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DE69812395T2 (de) * 1997-08-21 2004-02-05 Florida State University, Tallahassee Verfahren zur synthese von taxanen
US6002024A (en) * 1998-07-27 1999-12-14 Dabur Research Foundation Process for the isolation of 14β-hydroxy-10-deacetyl baccatin-III
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US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
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CN103804326A (zh) * 2012-11-15 2014-05-21 刘胜远 一种从含10-去乙酰基巴卡亭ⅲ的浸膏分离和提纯10-去乙酰基巴卡亭ⅲ的方法
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Citations (2)

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Publication number Priority date Publication date Assignee Title
AU1888792A (en) * 1991-04-19 1992-11-17 University Of Mississippi, The Methods and compositions for isolating taxanes
EP0553780A1 (en) * 1992-01-31 1993-08-04 INDENA S.p.A. A process for the extraction of taxol and derivatives thereof from plants of the genus taxus

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1888792A (en) * 1991-04-19 1992-11-17 University Of Mississippi, The Methods and compositions for isolating taxanes
EP0553780A1 (en) * 1992-01-31 1993-08-04 INDENA S.p.A. A process for the extraction of taxol and derivatives thereof from plants of the genus taxus

Also Published As

Publication number Publication date
HU226862B1 (en) 2009-12-28
CZ284615B6 (cs) 1999-01-13
LTIP1397A (en) 1994-11-25
SK280949B6 (sk) 2000-09-12
FR2696463A1 (fr) 1994-04-08
US5393895A (en) 1995-02-28
CZ287065B6 (cs) 2000-08-16
HU9500973D0 (en) 1995-06-28
AU5115593A (en) 1994-04-26
KR950703550A (ko) 1995-09-20
DE69308155D1 (de) 1997-03-27
LV10621B (en) 1995-10-20
KR100301236B1 (ko) 2001-11-22
EP0663910B1 (fr) 1997-02-12
NZ256450A (en) 1996-11-26
JPH08501792A (ja) 1996-02-27
PL177316B1 (pl) 1999-10-29
CZ84595A3 (en) 1995-09-13
RU95110687A (ru) 1996-12-27
FR2696463B1 (fr) 1994-11-25
MX9305771A (es) 1994-05-31
EE03126B1 (et) 1998-10-15
RU2107065C1 (ru) 1998-03-20
DK0663910T3 (da) 1997-03-10
SK43395A3 (en) 1995-08-09
JP3299754B2 (ja) 2002-07-08
NO951282L (no) 1995-04-03
ZA937313B (en) 1994-04-25
LT3398B (en) 1995-09-25
HUT72449A (en) 1996-04-29
CA2146373C (fr) 2006-08-29
UA44227C2 (uk) 2002-02-15
GR3022617T3 (en) 1997-05-31
FI951596A0 (fi) 1995-04-04
FI109794B (fi) 2002-10-15
FI951596L (fi) 1995-04-04
LV10621A (lv) 1995-04-20
NO310413B1 (no) 2001-07-02
CA2146373A1 (fr) 1994-04-14
DE69308155T2 (de) 1997-08-07
ES2098061T3 (es) 1997-04-16
EP0663910A1 (fr) 1995-07-26
GEP20001937B (en) 2000-02-05
NO951282D0 (no) 1995-04-03
TW255890B (esLanguage) 1995-09-01
PL308244A1 (en) 1995-07-24
WO1994007882A1 (fr) 1994-04-14
CN1085551A (zh) 1994-04-20
ATE148883T1 (de) 1997-02-15
CN1043530C (zh) 1999-06-02

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