AU666819B2 - Process for producing lignan compound - Google Patents

Process for producing lignan compound Download PDF

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Publication number
AU666819B2
AU666819B2 AU64379/94A AU6437994A AU666819B2 AU 666819 B2 AU666819 B2 AU 666819B2 AU 64379/94 A AU64379/94 A AU 64379/94A AU 6437994 A AU6437994 A AU 6437994A AU 666819 B2 AU666819 B2 AU 666819B2
Authority
AU
Australia
Prior art keywords
compound
synthesis
formula
preparation
document
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU64379/94A
Other languages
English (en)
Other versions
AU6437994A (en
Inventor
Shiro Kida
Sachio Mori
Shozo Takechi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of AU6437994A publication Critical patent/AU6437994A/en
Application granted granted Critical
Publication of AU666819B2 publication Critical patent/AU666819B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
AU64379/94A 1993-04-16 1994-04-12 Process for producing lignan compound Ceased AU666819B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8994493 1993-04-16
JP5-89944 1993-04-16
PCT/JP1994/000612 WO1994024087A1 (fr) 1993-04-16 1994-04-12 Procede pour produire un compose de lignane

Publications (2)

Publication Number Publication Date
AU6437994A AU6437994A (en) 1994-11-08
AU666819B2 true AU666819B2 (en) 1996-02-22

Family

ID=13984820

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64379/94A Ceased AU666819B2 (en) 1993-04-16 1994-04-12 Process for producing lignan compound

Country Status (13)

Country Link
US (1) US5488134A (cg-RX-API-DMAC7.html)
EP (1) EP0646570B1 (cg-RX-API-DMAC7.html)
JP (1) JP3411036B2 (cg-RX-API-DMAC7.html)
KR (1) KR100277242B1 (cg-RX-API-DMAC7.html)
CN (1) CN1046937C (cg-RX-API-DMAC7.html)
AT (1) ATE167662T1 (cg-RX-API-DMAC7.html)
AU (1) AU666819B2 (cg-RX-API-DMAC7.html)
CA (1) CA2138264C (cg-RX-API-DMAC7.html)
DE (1) DE69411243T2 (cg-RX-API-DMAC7.html)
DK (1) DK0646570T3 (cg-RX-API-DMAC7.html)
ES (1) ES2119190T3 (cg-RX-API-DMAC7.html)
TW (1) TW255886B (cg-RX-API-DMAC7.html)
WO (1) WO1994024087A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU685716B2 (en) * 1993-04-16 1998-01-22 Shionogi & Co., Ltd. 3-(3,4-dialkoxyphenyl)-1(3H)-isobenzofuranone dervatives, intermediates for synthetic lignans

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
KR100376281B1 (ko) * 1995-12-26 2003-09-26 에스케이케미칼주식회사 리그난의 제조방법
CA2305307C (en) 1997-09-29 2004-11-30 Meiji Seika Kaisha, Ltd. Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents
PT1140184E (pt) 1998-12-23 2003-10-31 Searle Llc Combinacoes de inibidores de proteina de transferencia de ester de colesterilo com derivados de acido nicotinico para indicacoes cardiovasculares
PL348503A1 (en) 1998-12-23 2002-05-20 Searle Llc Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
CA2356422C (en) 1998-12-23 2008-09-16 G.D. Searle Llc Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
KR20010102964A (ko) 1998-12-23 2001-11-17 윌리암스 로저 에이 심장혈관 징후를 위한 회장 담즙산 수송 억제인자 및피브린산 유도체의 조합물
DE69908644T2 (de) 1998-12-23 2004-05-13 G.D. Searle Llc, Chicago Kombnationen von cholesteryl ester transfer protein inhibitoren und gallensäure sequestriermitteln für kardiovaskuläre indikationen
US6462091B1 (en) 1998-12-23 2002-10-08 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications
CN1338945A (zh) 1998-12-23 2002-03-06 G·D·瑟尔有限公司 适用于心血管疾病的回肠胆汁酸转运抑制剂和胆汁酸螯合剂组合
WO2001068096A2 (en) * 2000-03-10 2001-09-20 Pharmacia Corporation Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
HK1052183A1 (zh) 2000-03-10 2003-09-05 Pharmacia Corporation 制造tetrahydrobenzothiepines的方法
JP2005518347A (ja) 2001-11-02 2005-06-23 ジー．ディー． サール エルエルシー 頂端ナトリウム共依存性胆汁酸輸送（ａｓｂｔ）およびタウロコール酸塩取り込みの阻害剤としての新規一および二フッ化ベンゾチエピン化合物
JP2005521653A (ja) 2002-01-17 2005-07-21 ファルマシア コーポレイション 先端ナトリウム同時依存性胆汁酸輸送（ａｓｂｔ）およびタウロコール酸塩取込みの阻害剤としての新規アルキル／アリールヒドロキシまたはケトチエピン化合物
GB0307918D0 (en) 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
EP2995317A1 (en) 2010-05-26 2016-03-16 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
JP6217938B2 (ja) 2011-10-28 2017-10-25 ルメナ ファーマシューティカルズ エルエルシー 小児の胆汁うっ滞性肝疾患の処置のための胆汁酸再循環阻害剤
MX363161B (es) 2011-10-28 2019-03-13 Lumena Pharmaceuticals Inc Inhibidores de la recirculación de ácidos biliares para el tratamiento de hipercolemia y enfermedad hepática colestásica.
EP2968230A2 (en) 2013-03-15 2016-01-20 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
CN105228615A (zh) 2013-03-15 2016-01-06 鲁美纳医药公司 用于治疗巴雷特食管和胃食管返流疾病的胆汁酸再循环抑制剂
US20220133738A1 (en) 2019-02-12 2022-05-05 Mirum Pharmaceuticals, Inc. Genotype and dose-dependent response to an asbti in patients with bile salt export pump deficiency

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008155A1 (fr) * 1991-10-17 1993-04-29 Shionogi & Co., Ltd. Analogue de lignane, sa production et medicament hypolipidemiant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0372422A (ja) * 1989-05-16 1991-03-27 Tanabe Seiyaku Co Ltd 抗脂血剤
JPH03157351A (ja) * 1989-11-13 1991-07-05 Tanabe Seiyaku Co Ltd ナフタレン誘導体及びその製法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008155A1 (fr) * 1991-10-17 1993-04-29 Shionogi & Co., Ltd. Analogue de lignane, sa production et medicament hypolipidemiant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU685716B2 (en) * 1993-04-16 1998-01-22 Shionogi & Co., Ltd. 3-(3,4-dialkoxyphenyl)-1(3H)-isobenzofuranone dervatives, intermediates for synthetic lignans

Also Published As

Publication number Publication date
ATE167662T1 (de) 1998-07-15
DE69411243D1 (de) 1998-07-30
EP0646570A1 (en) 1995-04-05
AU6437994A (en) 1994-11-08
CN1046937C (zh) 1999-12-01
EP0646570B1 (en) 1998-06-24
EP0646570A4 (en) 1995-08-09
TW255886B (cg-RX-API-DMAC7.html) 1995-09-01
WO1994024087A1 (fr) 1994-10-27
CA2138264C (en) 2004-04-06
KR950701902A (ko) 1995-05-17
KR100277242B1 (ko) 2001-02-01
JP3411036B2 (ja) 2003-05-26
CN1109685A (zh) 1995-10-04
US5488134A (en) 1996-01-30
CA2138264A1 (en) 1994-10-27
ES2119190T3 (es) 1998-10-01
DE69411243T2 (de) 1998-11-19
DK0646570T3 (da) 1998-10-26

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