AU614209B2 - Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof - Google Patents

Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof Download PDF

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Publication number
AU614209B2
AU614209B2 AU46845/89A AU4684589A AU614209B2 AU 614209 B2 AU614209 B2 AU 614209B2 AU 46845/89 A AU46845/89 A AU 46845/89A AU 4684589 A AU4684589 A AU 4684589A AU 614209 B2 AU614209 B2 AU 614209B2
Authority
AU
Australia
Prior art keywords
transdermal
therapeutical system
polymeric material
transdermal therapeutical
reservoir layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU46845/89A
Other languages
English (en)
Other versions
AU4684589A (en
Inventor
Thomas Hille
Hans-Rainer Hoffmann
Hans-Joachim Huber
Axel Knoch
Gerhard Schneider
Fritz Stanislaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of AU4684589A publication Critical patent/AU4684589A/en
Application granted granted Critical
Publication of AU614209B2 publication Critical patent/AU614209B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AU46845/89A 1988-12-22 1989-12-18 Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof Ceased AU614209B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3843239 1988-12-22
DE3843239A DE3843239C1 (ja) 1988-12-22 1988-12-22

Publications (2)

Publication Number Publication Date
AU4684589A AU4684589A (en) 1990-06-28
AU614209B2 true AU614209B2 (en) 1991-08-22

Family

ID=6369855

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46845/89A Ceased AU614209B2 (en) 1988-12-22 1989-12-18 Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof

Country Status (29)

Country Link
US (1) US5089267A (ja)
EP (1) EP0376067B1 (ja)
JP (1) JPH0784379B2 (ja)
KR (1) KR950015058B1 (ja)
CN (1) CN1045355A (ja)
AT (1) ATE105488T1 (ja)
AU (1) AU614209B2 (ja)
CA (1) CA2006404C (ja)
CS (1) CS277066B6 (ja)
DD (1) DD290580A5 (ja)
DE (2) DE3843239C1 (ja)
DK (1) DK651289A (ja)
ES (1) ES2056185T3 (ja)
FI (1) FI95775C (ja)
GE (1) GEP19960440B (ja)
HU (1) HU205252B (ja)
IE (1) IE64200B1 (ja)
IL (1) IL92680A (ja)
LT (1) LT3785B (ja)
MY (1) MY104491A (ja)
NO (1) NO180072C (ja)
NZ (1) NZ231907A (ja)
PH (1) PH25853A (ja)
PL (1) PL162690B1 (ja)
PT (1) PT92652B (ja)
RU (1) RU2011384C1 (ja)
UA (1) UA18868A (ja)
YU (1) YU47077B (ja)
ZA (1) ZA899878B (ja)

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Publication number Priority date Publication date Assignee Title
DE3843238C1 (ja) * 1988-12-22 1990-02-22 Lohmann Therapie Syst Lts
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
NZ237241A (en) * 1990-03-02 1993-11-25 Pharmetrix Corp Method for increasing the storage stability of physostigmine
DE4010079A1 (de) * 1990-03-29 1991-10-02 Lohmann Therapie Syst Lts Pharmazeutische formulierung zur behandlung des alkoholismus
WO1991015176A1 (en) * 1990-04-06 1991-10-17 Pharmetrix Corporation Device and method for enhanced administration of physostigmine
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
DE4238223C1 (de) * 1992-11-12 1994-05-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Verabreichung von Physostigmin an die Haut und Verfahren zu dessen Herstellung
US5409948A (en) * 1992-11-23 1995-04-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method for treating cognitive disorders with phenserine
DE4301782C1 (de) * 1993-01-23 1994-08-25 Lohmann Therapie Syst Lts Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit
DE4301783C1 (de) * 1993-01-23 1994-02-03 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil
DE4342174C1 (de) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System sowie ein Verfahren zur Herstellung eines transdermalen therapeutischen Systems zur kombinierten transdermalen Anwendung von Physostigmin und Scopolamin für die Prophylaxe und zur Vorbehandlung einer Vergiftung durch hochtoxische phosphororganische Nervengifte, insbesondere Soman und seine Verwendung
DE4400770C1 (de) * 1994-01-13 1995-02-02 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
JP3947564B2 (ja) 1994-10-28 2007-07-25 キンバリー クラーク ワールドワイド インコーポレイテッド 接着剤付き吸収性物品
TW304167B (ja) * 1995-01-30 1997-05-01 Lilly Co Eli
US5810960A (en) * 1995-03-08 1998-09-22 Nitto Denko Corporation Paint film-protective sheet
DE19706824C1 (de) * 1997-02-21 1998-03-26 Lohmann Therapie Syst Lts Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften
DE19906979B4 (de) 1999-02-19 2004-07-08 Lts Lohmann Therapie-Systeme Ag Verwendung von Desoxypeganin zur Behandlung der Nikotinabhängigkeit
DE10119862A1 (de) 2001-04-24 2002-11-07 Hf Arzneimittelforsch Gmbh Verwendung von Galanthamin zur Behandlung von Krankheitserscheinungen des zentralen Nervensystems aufgrund von Intoxikationen mit psychotropen Substanzen
DE10119863A1 (de) * 2001-04-24 2002-11-07 Hf Arzneimittelforsch Gmbh Verwendung von Desoxypeganin zur Behandlung von psychiatrischen oder zerebralen Krankheitserscheinungen
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
DE10134038A1 (de) * 2001-07-12 2003-02-06 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
DE10159745A1 (de) * 2001-12-05 2003-07-03 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit verbessertem Langzeittragekomfort
KR20050059072A (ko) * 2002-08-30 2005-06-17 알자 코포레이션 엠보싱 및 기록가능한 다층 지지 구조물
DE10318714B4 (de) * 2003-04-25 2006-03-23 Hf Arzneimittelforschung Gmbh Wirkstoff-Kombinationen und Therapien zur Bekämpfung des Alkoholmissbrauches
US20050182044A1 (en) * 2004-02-17 2005-08-18 Bruinsma Gosse B. Combinatorial therapy with an acetylcholinesterase inhibitor and (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3,-b]indol-5-yl phenylcarbamate
AT500143A1 (de) * 2004-04-22 2005-11-15 Sanochemia Pharmazeutika Ag Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung
CA2508585A1 (en) * 2004-06-01 2005-12-01 Axonyx, Inc. Transdermal delivery system for treatment of cognitive disorders
WO2005123068A2 (en) * 2004-06-08 2005-12-29 Axonyx, Inc. Methods of dealying alzheimer’s disease progression using a beta-amyloid precursor protein inhibitor and a hmg coa reductase inhibitor
CN1320005C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带烷烃基的丙烯酸酯的组合物
CN1320009C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带羟基基团的丙烯酸酯的组合物
CN1320008C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带羧基基团的丙烯酸酯的组合物
CN1320006C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带酯基基团的丙烯酸酯的组合物
CN1326894C (zh) * 2005-03-24 2007-07-18 上海交通大学 包含酯基部分带烷氧基的丙烯酸酯的组合物
CN1994290B (zh) * 2006-01-04 2011-03-16 上海医药工业研究院 卡巴拉汀透皮贴剂及其制备方法
GB0809905D0 (en) * 2008-06-02 2008-07-09 Secr Defence A Transdermal drug delivery device
KR101317158B1 (ko) 2011-02-18 2013-10-15 조선대학교산학협력단 갈란타민 또는 그의 염을 함유하는 경피흡수제제
DE102019201430A1 (de) 2019-02-05 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit Transportmedium
DE102019201431A1 (de) 2019-02-05 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit Feststoffreservoir

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US3921363A (en) 1974-05-17 1975-11-25 Preston Metal & Roofing Prod Cross member with end connector
JPS5620514A (en) * 1979-07-27 1981-02-26 Nitto Electric Ind Co Ltd Plaster for remedy of skin disease
JPS596285B2 (ja) * 1980-09-22 1984-02-10 日東電工株式会社 外用部材
JPS57116011A (en) * 1981-01-08 1982-07-19 Nitto Electric Ind Co Ltd Pharmaceutical preparation
JPS6066758A (ja) * 1983-09-21 1985-04-16 日東電工株式会社 医薬製剤
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IL72684A (en) * 1984-08-14 1989-02-28 Israel State Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs
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US4765985A (en) * 1985-03-05 1988-08-23 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
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US4911707A (en) * 1987-02-13 1990-03-27 Ciba-Geigy Corporation Monolithic user-activated transdermal therapeutic system
DE3743945A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung
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Also Published As

Publication number Publication date
AU4684589A (en) 1990-06-28
CS719189A3 (en) 1992-06-17
JPH0315477A (ja) 1991-01-23
IE894079L (en) 1990-06-22
FI896099A0 (fi) 1989-12-19
LT3785B (en) 1996-03-25
JPH0784379B2 (ja) 1995-09-13
MY104491A (en) 1994-04-30
CA2006404C (en) 1995-10-24
US5089267A (en) 1992-02-18
IE64200B1 (en) 1995-07-12
NO895171D0 (no) 1989-12-21
NO180072C (no) 1997-02-12
NO180072B (no) 1996-11-04
DE58907647D1 (de) 1994-06-16
DE3843239C1 (ja) 1990-02-22
HUT54889A (en) 1991-04-29
KR900009065A (ko) 1990-07-02
PT92652A (pt) 1990-06-29
CA2006404A1 (en) 1990-06-22
GEP19960440B (en) 1996-08-30
ZA899878B (en) 1990-09-26
IL92680A0 (en) 1990-09-17
UA18868A (uk) 1997-12-25
ES2056185T3 (es) 1994-10-01
NO895171L (no) 1990-06-25
EP0376067A2 (de) 1990-07-04
HU205252B (en) 1992-04-28
YU240789A (en) 1991-04-30
PL162690B1 (pl) 1993-12-31
FI95775C (fi) 1996-03-25
DK651289A (da) 1990-06-23
EP0376067A3 (en) 1990-12-27
CN1045355A (zh) 1990-09-19
FI95775B (fi) 1995-12-15
NZ231907A (en) 1991-10-25
PT92652B (pt) 1995-09-12
IL92680A (en) 1993-06-10
ATE105488T1 (de) 1994-05-15
YU47077B (sh) 1994-12-28
DK651289D0 (da) 1989-12-20
PH25853A (en) 1991-12-02
HU896713D0 (en) 1990-02-28
KR950015058B1 (ko) 1995-12-21
RU2011384C1 (ru) 1994-04-30
CS277066B6 (en) 1992-11-18
EP0376067B1 (de) 1994-05-11
DD290580A5 (de) 1991-06-06
LTIP1842A (en) 1995-08-25

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired