AU5541799A - Pharmaceuticals for the imaging of angiogenic disorders - Google Patents
Pharmaceuticals for the imaging of angiogenic disorders Download PDFInfo
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- AU5541799A AU5541799A AU55417/99A AU5541799A AU5541799A AU 5541799 A AU5541799 A AU 5541799A AU 55417/99 A AU55417/99 A AU 55417/99A AU 5541799 A AU5541799 A AU 5541799A AU 5541799 A AU5541799 A AU 5541799A
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Classifications
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- C07K—PEPTIDES
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- C07K7/64—Cyclic peptides containing only normal peptide links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
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- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8015098P | 1998-03-31 | 1998-03-31 | |
| US60080150 | 1998-03-31 | ||
| US11271598P | 1998-12-18 | 1998-12-18 | |
| US60112715 | 1998-12-18 | ||
| PCT/US1999/006826 WO1999058162A2 (en) | 1998-03-31 | 1999-03-29 | Pharmaceuticals for the imaging of angiogenic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU5541799A true AU5541799A (en) | 1999-11-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU55417/99A Abandoned AU5541799A (en) | 1998-03-31 | 1999-03-29 | Pharmaceuticals for the imaging of angiogenic disorders |
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|---|---|
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| EP (1) | EP1068224B1 (enExample) |
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| AT (1) | ATE295369T1 (enExample) |
| AU (1) | AU5541799A (enExample) |
| BR (1) | BR9909420A (enExample) |
| CA (1) | CA2324555A1 (enExample) |
| DE (1) | DE69925262T2 (enExample) |
| EA (1) | EA200001007A1 (enExample) |
| EE (1) | EE200000574A (enExample) |
| ES (1) | ES2241313T3 (enExample) |
| HU (1) | HUP0101468A2 (enExample) |
| IL (1) | IL138093A0 (enExample) |
| NO (1) | NO20004917L (enExample) |
| PL (1) | PL343804A1 (enExample) |
| SK (1) | SK13952000A3 (enExample) |
| WO (1) | WO1999058162A2 (enExample) |
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| US6749853B1 (en) * | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
| US5965132A (en) * | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US6537520B1 (en) | 1998-03-31 | 2003-03-25 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
| US6794518B1 (en) * | 1998-12-18 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
| US6989139B2 (en) * | 2000-02-15 | 2006-01-24 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| EP1281068B1 (en) * | 2000-05-08 | 2008-03-26 | TTP LabTech Ltd | Microphysiometer |
| EP1289565B1 (en) | 2000-06-02 | 2015-04-22 | Bracco Suisse SA | Compounds for targeting endothelial cells |
| US8263739B2 (en) | 2000-06-02 | 2012-09-11 | Bracco Suisse Sa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
| AU2001268710A1 (en) * | 2000-06-21 | 2002-01-02 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders for use in combination therapy |
| AU2001270025B2 (en) * | 2000-06-21 | 2005-08-18 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy |
| US20020122768A1 (en) * | 2000-07-06 | 2002-09-05 | Shuang Liu | Stable radiopharmaceutical compositions and methods for preparation thereof |
| JP2005506952A (ja) * | 2000-11-27 | 2005-03-10 | ブリストル−マイヤーズ・スクイブ・メディカル・イメージング・インコーポレイテッド | 心臓潅流およびビトロネクチンレセプター標的造影剤の同時造影 |
| TW593278B (en) | 2001-01-23 | 2004-06-21 | Wyeth Corp | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands |
| US7271180B2 (en) * | 2001-01-23 | 2007-09-18 | Wyeth | 1-Aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands |
| DE60231801D1 (de) | 2001-04-23 | 2009-05-14 | Mallinckrodt Inc | Tc und re markierte radioaktive glycosylierte octreotid-derivate |
| JP2004537573A (ja) * | 2001-08-08 | 2004-12-16 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | 心臓灌流およびビトロネクチン受容体を標的とするイメージング剤の同時イメージング |
| KR101159061B1 (ko) | 2001-10-22 | 2012-06-22 | 더 스크립스 리서치 인스티튜트 | 항체 표적화 화합물 |
| US7279150B2 (en) | 2002-01-24 | 2007-10-09 | Barnes-Jewish Hospital | Chelating agents with lipophilic carriers |
| JP4731117B2 (ja) | 2002-01-24 | 2011-07-20 | バーンズ−ジューイッシュ ホスピタル | インテグリン標的イメージング剤 |
| US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
| ES2506142T3 (es) * | 2002-03-01 | 2014-10-13 | Dyax Corp. | Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico |
| US20050250700A1 (en) * | 2002-03-01 | 2005-11-10 | Sato Aaron K | KDR and VEGF/KDR binding peptides |
| US7211240B2 (en) | 2002-03-01 | 2007-05-01 | Bracco International B.V. | Multivalent constructs for therapeutic and diagnostic applications |
| US7985402B2 (en) | 2002-03-01 | 2011-07-26 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
| US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| US7666979B2 (en) * | 2002-03-01 | 2010-02-23 | Bracco International B.V. | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same |
| US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
| US20050100963A1 (en) | 2002-03-01 | 2005-05-12 | Dyax Corporation | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| AU2003235489A1 (en) * | 2002-05-08 | 2003-11-11 | Tom Mcneil | High efficiency solid-state light source and methods of use and manufacture |
| US6961607B2 (en) * | 2002-07-31 | 2005-11-01 | Uzgiris Egidijus E | Method for assessing myocardial angiogenesis |
| US20040224986A1 (en) | 2002-08-16 | 2004-11-11 | Bart De Corte | Piperidinyl targeting compounds that selectively bind integrins |
| US20040122354A1 (en) * | 2002-09-05 | 2004-06-24 | Semba Charles P. | Infusion catheter having an integrated doppler transducer |
| US20040047917A1 (en) * | 2002-09-06 | 2004-03-11 | Stephen Wilson | Drug delivery and targeting with vitamin B12 conjugates |
| CA2499496C (fr) * | 2002-09-19 | 2012-04-24 | Centre National De La Recherche Scientifique - Cnrs | Synthese et caracterisation de nouveaux systemes de guidage et de vectorisation de molecules d'interet therapeutique vers des cellules cibles |
| WO2004069281A1 (en) * | 2003-01-30 | 2004-08-19 | The General Hospital Corporation | Bifunctional molecules comprising at least one integrin-binding and their use in imaging and therapy of angiogenesis and related disorders |
| EP2949658B1 (en) | 2003-03-03 | 2018-08-08 | Dyax Corp. | Peptides that specifically bind HGF receptor (cMet) and uses thereof |
| MXPA05012109A (es) * | 2003-05-12 | 2006-02-08 | Bristol Myers Squibb Pharma Co | Compuestos antagonistas del receptor de vitronectina y su uso en la preparacion de radiofarmaceuticos. |
| AU2004263136A1 (en) * | 2003-08-08 | 2005-02-17 | Barnes-Jewish Hospital | Emulsion particles for imaging and therapy and methods of use thereof |
| US20050112064A1 (en) * | 2003-08-12 | 2005-05-26 | Sonya Franklin | DNA-dependent MRI contrast agents |
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| EP1861127A1 (en) * | 2005-03-10 | 2007-12-05 | Bayer Schering Pharma Aktiengesellschaft | Chelators for radioactively labeled conjugates comprising a stabilizing sidechain |
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| CN101659694B (zh) * | 2009-05-06 | 2012-12-12 | 河北科技大学 | 抗肿瘤环五肽化合物及其制备方法 |
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| DE102013113156A1 (de) * | 2013-11-28 | 2015-05-28 | Freie Universität Berlin | Verbindung und Verfahren zur selektiven Radiomarkierung von Polypeptiden mittels Festphasensynthese |
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-
1999
- 1999-03-29 KR KR1020007010831A patent/KR20010042288A/ko not_active Withdrawn
- 1999-03-29 EP EP99941944A patent/EP1068224B1/en not_active Expired - Lifetime
- 1999-03-29 HU HU0101468A patent/HUP0101468A2/hu unknown
- 1999-03-29 CN CN99804710A patent/CN1295578A/zh active Pending
- 1999-03-29 PL PL99343804A patent/PL343804A1/xx unknown
- 1999-03-29 AU AU55417/99A patent/AU5541799A/en not_active Abandoned
- 1999-03-29 WO PCT/US1999/006826 patent/WO1999058162A2/en not_active Ceased
- 1999-03-29 EE EEP200000574A patent/EE200000574A/xx unknown
- 1999-03-29 CA CA002324555A patent/CA2324555A1/en not_active Abandoned
- 1999-03-29 SK SK1395-2000A patent/SK13952000A3/sk unknown
- 1999-03-29 EA EA200001007A patent/EA200001007A1/ru unknown
- 1999-03-29 AT AT99941944T patent/ATE295369T1/de not_active IP Right Cessation
- 1999-03-29 ES ES99941944T patent/ES2241313T3/es not_active Expired - Lifetime
- 1999-03-29 JP JP2000548013A patent/JP4487019B2/ja not_active Expired - Fee Related
- 1999-03-29 BR BR9909420-7A patent/BR9909420A/pt not_active IP Right Cessation
- 1999-03-29 DE DE69925262T patent/DE69925262T2/de not_active Expired - Lifetime
- 1999-03-29 IL IL13809399A patent/IL138093A0/xx unknown
- 1999-03-30 AR ARP990101448A patent/AR020586A1/es not_active Application Discontinuation
- 1999-03-30 US US09/281,474 patent/US20020001566A1/en not_active Abandoned
- 1999-03-30 US US09/281,207 patent/US6322770B1/en not_active Expired - Fee Related
-
2000
- 2000-09-29 NO NO20004917A patent/NO20004917L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4487019B2 (ja) | 2010-06-23 |
| US20020001566A1 (en) | 2002-01-03 |
| ES2241313T3 (es) | 2005-10-16 |
| PL343804A1 (en) | 2001-09-10 |
| EP1068224A2 (en) | 2001-01-17 |
| BR9909420A (pt) | 2001-09-25 |
| DE69925262T2 (de) | 2006-02-23 |
| IL138093A0 (en) | 2001-10-31 |
| NO20004917L (no) | 2000-11-02 |
| WO1999058162A3 (en) | 2000-04-06 |
| JP2002514611A (ja) | 2002-05-21 |
| NO20004917D0 (no) | 2000-09-29 |
| AR020586A1 (es) | 2002-05-22 |
| ATE295369T1 (de) | 2005-05-15 |
| KR20010042288A (ko) | 2001-05-25 |
| CA2324555A1 (en) | 1999-11-18 |
| CN1295578A (zh) | 2001-05-16 |
| EE200000574A (et) | 2002-10-15 |
| SK13952000A3 (sk) | 2001-12-03 |
| DE69925262D1 (de) | 2005-06-16 |
| EA200001007A1 (ru) | 2001-04-23 |
| WO1999058162A2 (en) | 1999-11-18 |
| US6322770B1 (en) | 2001-11-27 |
| HUP0101468A2 (hu) | 2001-08-28 |
| EP1068224B1 (en) | 2005-05-11 |
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