ATE295369T1 - Pharmazeutika zur bildgebung der angiogenischen krankheiten - Google Patents
Pharmazeutika zur bildgebung der angiogenischen krankheitenInfo
- Publication number
- ATE295369T1 ATE295369T1 AT99941944T AT99941944T ATE295369T1 AT E295369 T1 ATE295369 T1 AT E295369T1 AT 99941944 T AT99941944 T AT 99941944T AT 99941944 T AT99941944 T AT 99941944T AT E295369 T1 ATE295369 T1 AT E295369T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceuticals
- angiogenic diseases
- imaging angiogenic
- imaging
- diseases
- Prior art date
Links
- 230000002491 angiogenic effect Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8015098P | 1998-03-31 | 1998-03-31 | |
US11271598P | 1998-12-18 | 1998-12-18 | |
PCT/US1999/006826 WO1999058162A2 (en) | 1998-03-31 | 1999-03-29 | Pharmaceuticals for the imaging of angiogenic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE295369T1 true ATE295369T1 (de) | 2005-05-15 |
Family
ID=26763137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99941944T ATE295369T1 (de) | 1998-03-31 | 1999-03-29 | Pharmazeutika zur bildgebung der angiogenischen krankheiten |
Country Status (20)
Country | Link |
---|---|
US (2) | US6322770B1 (de) |
EP (1) | EP1068224B1 (de) |
JP (1) | JP4487019B2 (de) |
KR (1) | KR20010042288A (de) |
CN (1) | CN1295578A (de) |
AR (1) | AR020586A1 (de) |
AT (1) | ATE295369T1 (de) |
AU (1) | AU5541799A (de) |
BR (1) | BR9909420A (de) |
CA (1) | CA2324555A1 (de) |
DE (1) | DE69925262T2 (de) |
EA (1) | EA200001007A1 (de) |
EE (1) | EE200000574A (de) |
ES (1) | ES2241313T3 (de) |
HU (1) | HUP0101468A2 (de) |
IL (1) | IL138093A0 (de) |
NO (1) | NO20004917L (de) |
PL (1) | PL343804A1 (de) |
SK (1) | SK13952000A3 (de) |
WO (1) | WO1999058162A2 (de) |
Families Citing this family (60)
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---|---|---|---|---|
US5965132A (en) | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
US6749853B1 (en) * | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
US6537520B1 (en) | 1998-03-31 | 2003-03-25 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
US6794518B1 (en) * | 1998-12-18 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
US6989139B2 (en) * | 2000-02-15 | 2006-01-24 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
JP2003532877A (ja) * | 2000-05-08 | 2003-11-05 | アンテルユニヴェルシテール・ミクロ−エレクトロニカ・サントリュム・ヴェー・ゼッド・ドゥブルヴェ | ハイスループットリードプロファイリング方法 |
US8263739B2 (en) | 2000-06-02 | 2012-09-11 | Bracco Suisse Sa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
CA2410887C (en) | 2000-06-02 | 2012-07-24 | Bracco Research Usa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
AU2001268710A1 (en) * | 2000-06-21 | 2002-01-02 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders for use in combination therapy |
AU2001270025B2 (en) * | 2000-06-21 | 2005-08-18 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy |
EP1311301A2 (de) * | 2000-07-06 | 2003-05-21 | Bristol-Myers Squibb Pharma Company | Stabile radiopharmazeutische formulierungen |
CA2429956A1 (en) | 2000-11-27 | 2002-07-18 | Alan P. Carpenter, Jr. | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent |
TW593278B (en) * | 2001-01-23 | 2004-06-21 | Wyeth Corp | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands |
US7271180B2 (en) * | 2001-01-23 | 2007-09-18 | Wyeth | 1-Aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands |
EP1381396B1 (de) | 2001-04-23 | 2009-04-01 | Mallinckrodt Inc. | Tc und re markierte radioaktive glycosylierte octreotid-derivate |
WO2003013346A2 (en) * | 2001-08-08 | 2003-02-20 | Bristol-Myers Squibb Pharma Company | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent |
CN100560131C (zh) | 2001-10-22 | 2009-11-18 | 斯克里普斯研究学院 | 抗体靶向化合物 |
BR0307206A (pt) * | 2002-01-24 | 2004-12-21 | Barnes Jewish Hospital | Agentes de formação de imagem direcionados por integrina |
US7279150B2 (en) | 2002-01-24 | 2007-10-09 | Barnes-Jewish Hospital | Chelating agents with lipophilic carriers |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US20050250700A1 (en) * | 2002-03-01 | 2005-11-10 | Sato Aaron K | KDR and VEGF/KDR binding peptides |
US7666979B2 (en) | 2002-03-01 | 2010-02-23 | Bracco International B.V. | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same |
US7985402B2 (en) | 2002-03-01 | 2011-07-26 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
CA2513044A1 (en) * | 2002-03-01 | 2004-08-05 | Dyax Corp. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
US7211240B2 (en) | 2002-03-01 | 2007-05-01 | Bracco International B.V. | Multivalent constructs for therapeutic and diagnostic applications |
EP2301587B1 (de) * | 2002-03-01 | 2014-06-25 | Dyax Corp. | KDR- und VEGF/KDR-bindende Peptide sowie ihre Verwendung bei der Diagnose und Therapie |
ATE535009T1 (de) * | 2002-05-08 | 2011-12-15 | Phoseon Technology Inc | Hocheffiziente halbleiter-lichtquelle sowie verfahren zu deren verwendung und herstellung |
US6961607B2 (en) * | 2002-07-31 | 2005-11-01 | Uzgiris Egidijus E | Method for assessing myocardial angiogenesis |
US20040224986A1 (en) | 2002-08-16 | 2004-11-11 | Bart De Corte | Piperidinyl targeting compounds that selectively bind integrins |
WO2004022153A2 (en) * | 2002-09-05 | 2004-03-18 | Genentech, Inc. | Infusion catheter having an integrated doppler transducer |
US20040047917A1 (en) * | 2002-09-06 | 2004-03-11 | Stephen Wilson | Drug delivery and targeting with vitamin B12 conjugates |
DE60310958T2 (de) * | 2002-09-19 | 2007-10-11 | Centre National De La Recherche Scientifique (Cnrs) | Synthese und charakterisierung neuer systeme zum hinführen und zur vektorisierung von molekülen von therapeutischem interesse zu targetzellen |
WO2004069281A1 (en) * | 2003-01-30 | 2004-08-19 | The General Hospital Corporation | Bifunctional molecules comprising at least one integrin-binding and their use in imaging and therapy of angiogenesis and related disorders |
CA2517939C (en) | 2003-03-03 | 2015-11-24 | Dyax Corp. | Peptides that specifically bind hgf receptor (cmet) and uses thereof |
CA2525396A1 (en) * | 2003-05-12 | 2004-11-25 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist compounds and their use in the preparation of radiopharmaceuticals |
CA2534426A1 (en) * | 2003-08-08 | 2005-02-17 | Barnes-Jewish Hospital | Emulsion particles for imaging and therapy and methods of use thereof |
US20050112064A1 (en) * | 2003-08-12 | 2005-05-26 | Sonya Franklin | DNA-dependent MRI contrast agents |
CA2559889A1 (en) * | 2004-01-16 | 2005-08-25 | Barnes-Jewish Hospital | Targeted atherosclerosis treatment |
JP2007523248A (ja) * | 2004-02-23 | 2007-08-16 | ダウ グローバル テクノロジーズ インコーポレイティド | 低表面エネルギー基体接着用水性接着剤 |
AU2005253962A1 (en) | 2004-06-09 | 2005-12-29 | Kereos, Inc. | Lipophilic derivatives of chelate monoamides |
EP1612529B1 (de) * | 2004-07-02 | 2007-04-11 | Vivactis NV | Messung der Wärme erzeugt durch einen chemischen oder biologischen Prozess. |
JP2008538204A (ja) * | 2005-03-10 | 2008-10-16 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | 安定化側鎖を含む放射性標識複合体キレート剤 |
WO2006119013A2 (en) * | 2005-04-29 | 2006-11-09 | Wyeth | Nogo receptor functional motifs and peptide mimetics related thereto and methods of using the same |
WO2007048127A2 (en) * | 2005-10-20 | 2007-04-26 | The Scripps Research Institute | Fc labeling for immunostaining and immunotargeting |
WO2007070827A2 (en) * | 2005-12-15 | 2007-06-21 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardium perfusion imaging |
AU2007244705A1 (en) * | 2006-04-27 | 2007-11-08 | Barnes-Jewish Hospital | Detection and imaging of target tissue |
AU2007303465A1 (en) * | 2006-09-29 | 2008-04-10 | Washington University | Combinations for treatment of neovasculature |
WO2008073842A1 (en) * | 2006-12-08 | 2008-06-19 | Molecular Image Inc. | Methods for diagnosis and monitoring of neurologic diseases using magnetic resonance methods |
US8194963B2 (en) * | 2008-03-10 | 2012-06-05 | Siemens Medical Solutions Usa, Inc. | Efficient estimator of pharmacokinetic parameters in breast MRI |
KR20140001257A (ko) | 2008-05-13 | 2014-01-06 | 유니버시티 오브 캔사스 | 금속 추출 펩타이드(map) 태그 및 관련된 방법 |
US20100178245A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
US8518927B2 (en) | 2009-02-10 | 2013-08-27 | The Scripps Research Institute | Chemically programmed vaccination |
CN101659694B (zh) * | 2009-05-06 | 2012-12-12 | 河北科技大学 | 抗肿瘤环五肽化合物及其制备方法 |
WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
WO2014160903A2 (en) * | 2013-03-27 | 2014-10-02 | Theranos, Inc. | Biological sample processing |
AU2014251388B2 (en) * | 2013-04-12 | 2017-03-30 | Evox Therapeutics Limited | Therapeutic delivery vesicles |
DE102013113156A1 (de) * | 2013-11-28 | 2015-05-28 | Freie Universität Berlin | Verbindung und Verfahren zur selektiven Radiomarkierung von Polypeptiden mittels Festphasensynthese |
KR102548998B1 (ko) * | 2020-03-31 | 2023-06-29 | 재단법인 아산사회복지재단 | 혈전영상을 위한 방사성의약품 및 조성물 |
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US4957939A (en) | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
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ES2114209T3 (es) | 1993-07-19 | 1998-05-16 | Resolution Pharm Inc | Queladores de radionuclidos de tipo hidrazino que tienen una configuracion n3s. |
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EP0762882A4 (de) | 1994-06-29 | 2002-09-11 | Smithkline Beecham Corp | Vibronectin-rezeptor-antagonisten |
DE69519929T2 (de) | 1994-07-11 | 2001-05-23 | Univ Texas | Verfahren und zusammensetzungen für die spezifische koagulation von tumorgefässen |
ATE203234T1 (de) | 1995-08-30 | 2001-08-15 | Searle & Co | Meta-guanidine, harnstoff, thioharnstoff oder azacyklische aminobenzoesäure-derivate als integrin antagonisten |
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-
1999
- 1999-03-29 WO PCT/US1999/006826 patent/WO1999058162A2/en active IP Right Grant
- 1999-03-29 CN CN99804710A patent/CN1295578A/zh active Pending
- 1999-03-29 JP JP2000548013A patent/JP4487019B2/ja not_active Expired - Fee Related
- 1999-03-29 EE EEP200000574A patent/EE200000574A/xx unknown
- 1999-03-29 BR BR9909420-7A patent/BR9909420A/pt not_active IP Right Cessation
- 1999-03-29 AT AT99941944T patent/ATE295369T1/de not_active IP Right Cessation
- 1999-03-29 ES ES99941944T patent/ES2241313T3/es not_active Expired - Lifetime
- 1999-03-29 KR KR1020007010831A patent/KR20010042288A/ko not_active Application Discontinuation
- 1999-03-29 SK SK1395-2000A patent/SK13952000A3/sk unknown
- 1999-03-29 PL PL99343804A patent/PL343804A1/xx unknown
- 1999-03-29 EA EA200001007A patent/EA200001007A1/ru unknown
- 1999-03-29 AU AU55417/99A patent/AU5541799A/en not_active Abandoned
- 1999-03-29 CA CA002324555A patent/CA2324555A1/en not_active Abandoned
- 1999-03-29 IL IL13809399A patent/IL138093A0/xx unknown
- 1999-03-29 EP EP99941944A patent/EP1068224B1/de not_active Expired - Lifetime
- 1999-03-29 HU HU0101468A patent/HUP0101468A2/hu unknown
- 1999-03-29 DE DE69925262T patent/DE69925262T2/de not_active Expired - Lifetime
- 1999-03-30 AR ARP990101448A patent/AR020586A1/es not_active Application Discontinuation
- 1999-03-30 US US09/281,207 patent/US6322770B1/en not_active Expired - Fee Related
- 1999-03-30 US US09/281,474 patent/US20020001566A1/en not_active Abandoned
-
2000
- 2000-09-29 NO NO20004917A patent/NO20004917L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2324555A1 (en) | 1999-11-18 |
JP4487019B2 (ja) | 2010-06-23 |
KR20010042288A (ko) | 2001-05-25 |
CN1295578A (zh) | 2001-05-16 |
PL343804A1 (en) | 2001-09-10 |
ES2241313T3 (es) | 2005-10-16 |
AU5541799A (en) | 1999-11-29 |
EP1068224B1 (de) | 2005-05-11 |
US20020001566A1 (en) | 2002-01-03 |
WO1999058162A3 (en) | 2000-04-06 |
AR020586A1 (es) | 2002-05-22 |
NO20004917D0 (no) | 2000-09-29 |
HUP0101468A2 (hu) | 2001-08-28 |
JP2002514611A (ja) | 2002-05-21 |
WO1999058162A2 (en) | 1999-11-18 |
NO20004917L (no) | 2000-11-02 |
IL138093A0 (en) | 2001-10-31 |
BR9909420A (pt) | 2001-09-25 |
EP1068224A2 (de) | 2001-01-17 |
EE200000574A (et) | 2002-10-15 |
DE69925262D1 (de) | 2005-06-16 |
SK13952000A3 (sk) | 2001-12-03 |
DE69925262T2 (de) | 2006-02-23 |
EA200001007A1 (ru) | 2001-04-23 |
US6322770B1 (en) | 2001-11-27 |
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