AU3024399A - Controlled release composition - Google Patents
Controlled release compositionInfo
- Publication number
- AU3024399A AU3024399A AU30243/99A AU3024399A AU3024399A AU 3024399 A AU3024399 A AU 3024399A AU 30243/99 A AU30243/99 A AU 30243/99A AU 3024399 A AU3024399 A AU 3024399A AU 3024399 A AU3024399 A AU 3024399A
- Authority
- AU
- Australia
- Prior art keywords
- composition
- matrix
- water
- aqueous medium
- erosion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000013270 controlled release Methods 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 230000003628 erosive effect Effects 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 239000002702 enteric coating Substances 0.000 abstract 1
- 238000009505 enteric coating Methods 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000003607 modifier Substances 0.000 abstract 1
- 239000012875 nonionic emulsifier Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 239000002344 surface layer Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98610009 | 1998-04-03 | ||
| EP98610009 | 1998-04-03 | ||
| PCT/DK1999/000174 WO1999051208A1 (en) | 1998-04-03 | 1999-03-25 | Controlled release composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU3024399A true AU3024399A (en) | 1999-10-25 |
Family
ID=8235847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU30243/99A Abandoned AU3024399A (en) | 1998-04-03 | 1999-03-25 | Controlled release composition |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7883722B2 (enExample) |
| EP (1) | EP1067910B1 (enExample) |
| JP (1) | JP4533531B2 (enExample) |
| AT (1) | ATE267589T1 (enExample) |
| AU (1) | AU3024399A (enExample) |
| CA (1) | CA2327685C (enExample) |
| DE (1) | DE69917618T2 (enExample) |
| DK (1) | DK1067910T3 (enExample) |
| ES (1) | ES2221370T3 (enExample) |
| WO (1) | WO1999051208A1 (enExample) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999051208A1 (en) | 1998-04-03 | 1999-10-14 | Bm Research A/S | Controlled release composition |
| WO2003024429A1 (en) * | 2001-09-21 | 2003-03-27 | Egalet A/S | Polymer release system |
| DE60224293T2 (de) | 2001-09-21 | 2008-12-11 | Egalet A/S | Feste dispersionen mit kontrollierter freisetzung von carvedilol |
| WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| GB0203296D0 (en) | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US8637512B2 (en) | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| GB0222612D0 (en) * | 2002-09-30 | 2002-11-06 | Univ Gent | Controlled delivery system for bioactive substances |
| MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
| WO2004041252A1 (en) * | 2002-11-08 | 2004-05-21 | Egalet A/S | Controlled release carvedilol compositions |
| ATE495732T1 (de) | 2003-03-26 | 2011-02-15 | Egalet As | Morphin-system mit kontrollierter freisetzung |
| CA2520312C (en) | 2003-03-26 | 2013-06-18 | Egalet A/S | Matrix compositions for controlled delivery of drug substances |
| CN102525993B (zh) | 2003-04-24 | 2017-04-12 | 佳高泰克有限公司 | 具有限定内核几何形状的缓释片剂 |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| GB0318824D0 (en) * | 2003-08-11 | 2003-09-10 | Glaxo Group Ltd | Novel composition |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| US20060078623A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
| DE102004043863A1 (de) | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
| PL2801354T3 (pl) * | 2004-10-08 | 2017-08-31 | Forward Pharma A/S | Kompozycje farmaceutyczne o kontrolowanym uwalnianiu zawierające ester kwasu fumarowego |
| US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
| WO2006070930A1 (en) * | 2004-12-27 | 2006-07-06 | Eisai R & D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
| US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| JP5161075B2 (ja) * | 2005-06-03 | 2013-03-13 | エガレット エイ/エス | 分散媒体の第1フラクションとマトリックスの第2フラクションを有し、第2フラクションが胃腸の液体に少なくとも部分的に最初に曝される固形の医薬組成物 |
| ES2400446T5 (es) | 2006-08-03 | 2017-03-13 | Horizon Pharma Ag | Tratamiento con glucocorticoides de liberación retardada de una enfermedad reumática |
| EP1920767A1 (en) * | 2006-11-09 | 2008-05-14 | Abbott GmbH & Co. KG | Melt-processed imatinib dosage form |
| CA2930487A1 (en) * | 2007-01-16 | 2008-07-24 | Egalet Ltd. | Use of i) a polyglycol and ii) an active drug substance for the preparation of a pharmaceutical composition for i)mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse |
| EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| EP2249811A1 (en) | 2008-01-25 | 2010-11-17 | Grünenthal GmbH | Pharmaceutical dosage form |
| US8642831B2 (en) | 2008-02-29 | 2014-02-04 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
| KR101690094B1 (ko) | 2008-05-09 | 2016-12-27 | 그뤼넨탈 게엠베하 | 분무 응결 단계의 사용하에 중간 분말 제형 및 최종 고체 제형을 제조하는 방법 |
| CA2734095A1 (en) * | 2008-08-14 | 2010-02-18 | Bioneer A/S | Coated tablets with a remaining degradation surface over the time |
| WO2010089132A1 (en) | 2009-02-06 | 2010-08-12 | Egalet A/S | Immediate release composition resistant to abuse by intake of alcohol |
| ES2607209T3 (es) | 2009-02-06 | 2017-03-29 | Egalet Ltd. | Composiciones farmacéuticas resistentes al abuso |
| CN102458368B (zh) * | 2009-05-13 | 2014-02-26 | 巴斯夫欧洲公司 | 含有基于聚醚的共聚物与微水溶性聚合物组合的固体药物制剂 |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
| SI2456424T1 (sl) | 2009-07-22 | 2013-10-30 | Gruenenthal Gmbh | Oksidacijsko stabilizirana odmerna oblika, varna pred zlorabo |
| AR077493A1 (es) | 2009-07-22 | 2011-08-31 | Gruenenthal Gmbh | Composicion farmaceutica extruida en caliente con liberacion controlada. procedimiento de preparacion |
| EP2540317A4 (en) * | 2010-02-22 | 2014-04-16 | Daiichi Sankyo Co Ltd | SOLID PREPARATION WITH DELAYED RELEASE FOR ORAL ADMINISTRATION |
| JP2013522246A (ja) | 2010-03-15 | 2013-06-13 | フェロサン メディカル デバイシーズ エイ/エス | 止血および/または創傷治癒を促進するための方法 |
| CN103037870B (zh) | 2010-05-12 | 2016-05-25 | 斯派克托姆制药公司 | 碱式碳酸镧、碳酸氧镧及其制造方法和用途 |
| MX2013002377A (es) | 2010-09-02 | 2013-04-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a manipulacion que comprende una sal inorganica. |
| PL2611425T3 (pl) | 2010-09-02 | 2014-09-30 | Gruenenthal Gmbh | Odporna na ingerencję postać dawki zawierająca polimer anionowy |
| JP2014524925A (ja) | 2011-07-29 | 2014-09-25 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時薬剤放出を提供するタンパーレジスタント錠剤 |
| EP2736497B1 (en) | 2011-07-29 | 2017-08-23 | Grünenthal GmbH | Tamper-resistant tablet providing immediate drug release |
| MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
| EP2822474B1 (en) | 2012-03-06 | 2018-05-02 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
| AR090695A1 (es) | 2012-04-18 | 2014-12-03 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| EP2977066A3 (en) | 2012-06-12 | 2016-07-27 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
| NZ704011A (en) | 2012-07-06 | 2016-04-29 | Egalet Ltd | Abuse deterrent pharmaceutical compositions for controlled release |
| MX371432B (es) | 2013-05-29 | 2020-01-30 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido que contiene una o mas particulas. |
| US9737490B2 (en) | 2013-05-29 | 2017-08-22 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
| WO2014202760A2 (en) | 2013-06-21 | 2014-12-24 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
| EA032465B1 (ru) | 2013-07-12 | 2019-05-31 | Грюненталь Гмбх | Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления |
| BR112016010482B1 (pt) | 2013-11-26 | 2022-11-16 | Grünenthal GmbH | Preparação de uma composição farmacêutica em pó por meio de criomoagem |
| BR112016013322B1 (pt) | 2013-12-11 | 2020-07-21 | Ferrosan Medical Devices A/S | métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit |
| EP3082781A1 (en) | 2013-12-16 | 2016-10-26 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion |
| EP3106152B1 (en) * | 2014-02-12 | 2021-02-17 | Sawai Pharmaceutical Co., Ltd. | Orally disintegrating tablet coated with film |
| MX2016014738A (es) | 2014-05-12 | 2017-03-06 | Gruenenthal Gmbh | Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol. |
| MX2016015417A (es) | 2014-05-26 | 2017-02-22 | Gruenenthal Gmbh | Multiparticulas protegidas contra vertido de dosis etanolico. |
| AU2015333206B2 (en) | 2014-10-13 | 2019-07-11 | Ferrosan Medical Devices A/S. | Dry composition for use in haemostasis and wound healing |
| EP3237041B1 (en) | 2014-12-24 | 2020-01-29 | Ferrosan Medical Devices A/S | Syringe for retaining and mixing first and second substances |
| EA035434B1 (ru) | 2015-04-24 | 2020-06-15 | Грюненталь Гмбх | Защищенная от применения не по назначению лекарственная форма с немедленным высвобождением и устойчивостью к экстракции растворителями |
| CA2986981A1 (en) | 2015-07-03 | 2017-01-12 | Ferrosan Medical Devices A/S | Syringe for mixing two components and for retaining a vacuum in a storage condition |
| WO2017042325A1 (en) | 2015-09-10 | 2017-03-16 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
| EP3790600B1 (en) | 2018-05-09 | 2023-12-27 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1430684A (en) | 1972-06-26 | 1976-03-31 | Lowey H | Prolonged release lozenges |
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| WO2003024430A1 (en) * | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| DE60224293T2 (de) * | 2001-09-21 | 2008-12-11 | Egalet A/S | Feste dispersionen mit kontrollierter freisetzung von carvedilol |
| WO2003024429A1 (en) * | 2001-09-21 | 2003-03-27 | Egalet A/S | Polymer release system |
| HUP0401686A3 (en) * | 2001-09-28 | 2008-04-28 | Mcneil Ppc Inc | Dosage forms having an inner core and outer shell with different shapes |
| WO2004041252A1 (en) * | 2002-11-08 | 2004-05-21 | Egalet A/S | Controlled release carvedilol compositions |
| ATE495732T1 (de) * | 2003-03-26 | 2011-02-15 | Egalet As | Morphin-system mit kontrollierter freisetzung |
| CA2520312C (en) * | 2003-03-26 | 2013-06-18 | Egalet A/S | Matrix compositions for controlled delivery of drug substances |
| EP1646367A4 (en) | 2003-07-21 | 2011-06-15 | Nesher Solutions Ltd | ORAL DOSAGE FORMS WITH CONTROLLED RELEASE ON GELLAN RUBBER BASE A NEW PLATFORM TECHNOLOGY FOR MAGNETIC RETENTION |
| KR100782918B1 (ko) | 2003-09-19 | 2007-12-07 | 펜웨스트 파머슈티칼즈 컴파니 | 지연 방출성 제형 |
| EP1732513A2 (en) * | 2003-12-31 | 2006-12-20 | Alpharma, Inc. | Rosiglitazone formulations |
| JP5161075B2 (ja) * | 2005-06-03 | 2013-03-13 | エガレット エイ/エス | 分散媒体の第1フラクションとマトリックスの第2フラクションを有し、第2フラクションが胃腸の液体に少なくとも部分的に最初に曝される固形の医薬組成物 |
-
1999
- 1999-03-25 WO PCT/DK1999/000174 patent/WO1999051208A1/en not_active Ceased
- 1999-03-25 CA CA002327685A patent/CA2327685C/en not_active Expired - Fee Related
- 1999-03-25 JP JP2000541979A patent/JP4533531B2/ja not_active Expired - Fee Related
- 1999-03-25 DE DE69917618T patent/DE69917618T2/de not_active Expired - Lifetime
- 1999-03-25 EP EP99911627A patent/EP1067910B1/en not_active Expired - Lifetime
- 1999-03-25 ES ES99911627T patent/ES2221370T3/es not_active Expired - Lifetime
- 1999-03-25 AT AT99911627T patent/ATE267589T1/de active
- 1999-03-25 AU AU30243/99A patent/AU3024399A/en not_active Abandoned
- 1999-03-25 DK DK99911627T patent/DK1067910T3/da active
-
2004
- 2004-05-14 US US10/845,522 patent/US7883722B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050089569A1 (en) | 2005-04-28 |
| ATE267589T1 (de) | 2004-06-15 |
| JP2002510616A (ja) | 2002-04-09 |
| ES2221370T3 (es) | 2004-12-16 |
| JP4533531B2 (ja) | 2010-09-01 |
| US7883722B2 (en) | 2011-02-08 |
| WO1999051208A1 (en) | 1999-10-14 |
| EP1067910A1 (en) | 2001-01-17 |
| DE69917618T2 (de) | 2005-06-23 |
| CA2327685C (en) | 2008-11-18 |
| EP1067910B1 (en) | 2004-05-26 |
| DE69917618D1 (de) | 2004-07-01 |
| CA2327685A1 (en) | 1999-10-14 |
| DK1067910T3 (da) | 2004-10-04 |
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Legal Events
| Date | Code | Title | Description |
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| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |