DK1067910T3 - Komposition med styret afgivelse - Google Patents
Komposition med styret afgivelseInfo
- Publication number
- DK1067910T3 DK1067910T3 DK99911627T DK99911627T DK1067910T3 DK 1067910 T3 DK1067910 T3 DK 1067910T3 DK 99911627 T DK99911627 T DK 99911627T DK 99911627 T DK99911627 T DK 99911627T DK 1067910 T3 DK1067910 T3 DK 1067910T3
- Authority
- DK
- Denmark
- Prior art keywords
- composition
- matrix
- water
- aqueous medium
- erosion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98610009 | 1998-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1067910T3 true DK1067910T3 (da) | 2004-10-04 |
Family
ID=8235847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99911627T DK1067910T3 (da) | 1998-04-03 | 1999-03-25 | Komposition med styret afgivelse |
Country Status (10)
Country | Link |
---|---|
US (1) | US7883722B2 (da) |
EP (1) | EP1067910B1 (da) |
JP (1) | JP4533531B2 (da) |
AT (1) | ATE267589T1 (da) |
AU (1) | AU3024399A (da) |
CA (1) | CA2327685C (da) |
DE (1) | DE69917618T2 (da) |
DK (1) | DK1067910T3 (da) |
ES (1) | ES2221370T3 (da) |
WO (1) | WO1999051208A1 (da) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2221370T3 (es) | 1998-04-03 | 2004-12-16 | Egalet A/S | Composicion de liberacion controlada. |
DE60224293T2 (de) * | 2001-09-21 | 2008-12-11 | Egalet A/S | Feste dispersionen mit kontrollierter freisetzung von carvedilol |
US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
GB0203296D0 (en) | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
US8637512B2 (en) | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
GB0222612D0 (en) * | 2002-09-30 | 2002-11-06 | Univ Gent | Controlled delivery system for bioactive substances |
MY148805A (en) * | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
WO2004041252A1 (en) | 2002-11-08 | 2004-05-21 | Egalet A/S | Controlled release carvedilol compositions |
DE602004025159D1 (de) | 2003-03-26 | 2010-03-04 | Egalet As | Matrixzubereitungen für die kontrollierte Darreichung von Arzneistoffen |
EP2301526B1 (en) | 2003-03-26 | 2016-03-23 | Egalet Ltd. | Morphine controlled release system |
JP4790597B2 (ja) | 2003-04-24 | 2011-10-12 | ヤゴテック アーゲー | 規定されたコア幾何学的配置を有する遅延放出錠 |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
GB0318824D0 (en) * | 2003-08-11 | 2003-09-10 | Glaxo Group Ltd | Novel composition |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
JP2008509933A (ja) * | 2004-08-13 | 2008-04-03 | エミスフェアー・テクノロジーズ・インク | 送達剤のマイクロ粒子またはナノ粒子を含む医薬製剤 |
DE102004043863A1 (de) | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
DE14172396T1 (de) * | 2004-10-08 | 2015-01-08 | Forward Pharma A/S | Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester |
US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
NZ555693A (en) * | 2004-12-27 | 2010-10-29 | Eisai R&D Man Co Ltd | Matrix type sustained-release preparation containing donepezil |
US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
EP1895989A2 (en) * | 2005-06-03 | 2008-03-12 | Egalet A/S | A solid pharmaceutical composition with a first fraction of a dispersion medium and a second fraction of a matrix, the latter being at least partially first exposed to gastrointestinal fluids |
EP2049123B2 (en) | 2006-08-03 | 2016-08-24 | Horizon Pharma AG | Delayed-release glucocorticoid treatment of rheumatoid disease |
EP1920767A1 (en) * | 2006-11-09 | 2008-05-14 | Abbott GmbH & Co. KG | Melt-processed imatinib dosage form |
NZ577560A (en) * | 2007-01-16 | 2012-01-12 | Egalet Ltd | Use of i) a polyglycol and ii) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse |
NZ580972A (en) | 2007-06-04 | 2012-02-24 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
JP5774853B2 (ja) | 2008-01-25 | 2015-09-09 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 医薬投薬形 |
CA2716872C (en) | 2008-02-29 | 2015-02-10 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
WO2009135680A1 (en) | 2008-05-09 | 2009-11-12 | Grünenthal GmbH | Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step |
CA2734095A1 (en) * | 2008-08-14 | 2010-02-18 | Bioneer A/S | Coated tablets with a remaining degradation surface over the time |
NZ594208A (en) | 2009-02-06 | 2012-10-26 | Egalet Ltd | Pharmaceutical compositions resistant to abuse |
AU2010211220B2 (en) | 2009-02-06 | 2013-08-01 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
CN102458368B (zh) * | 2009-05-13 | 2014-02-26 | 巴斯夫欧洲公司 | 含有基于聚醚的共聚物与微水溶性聚合物组合的固体药物制剂 |
CA2766179A1 (en) | 2009-06-24 | 2010-12-29 | Egalet Ltd. | Controlled release formulations |
CA2765971C (en) | 2009-07-22 | 2017-08-22 | Gruenenthal Gmbh | Hot-melt extruded controlled release dosage form |
AU2010275755B2 (en) | 2009-07-22 | 2014-04-24 | Grünenthal GmbH | Oxidation-stabilized tamper-resistant dosage form |
TW201132646A (en) * | 2010-02-22 | 2011-10-01 | Daiichi Sankyo Co Ltd | Oral solid extended release dosage form |
JP2013522246A (ja) | 2010-03-15 | 2013-06-13 | フェロサン メディカル デバイシーズ エイ/エス | 止血および/または創傷治癒を促進するための方法 |
US8961917B2 (en) | 2010-05-12 | 2015-02-24 | Spectrum Pharmaceuticals, Inc. | Lanthanum carbonate hydroxide, lanthanum oxycarbonate and methods of their manufacture and use |
EP2611426B1 (en) | 2010-09-02 | 2014-06-25 | Grünenthal GmbH | Tamper resistant dosage form comprising inorganic salt |
PL2611425T3 (pl) | 2010-09-02 | 2014-09-30 | Gruenenthal Gmbh | Odporna na ingerencję postać dawki zawierająca polimer anionowy |
HUE034710T2 (hu) | 2011-07-29 | 2018-02-28 | Gruenenthal Gmbh | Visszaéléssel szemben ellenálló, azonnali hatóanyagfelszabadulást biztosító tabletta |
PT2736495T (pt) | 2011-07-29 | 2017-11-30 | Gruenenthal Gmbh | Comprimido resistente à adulteração proporcionando libertação imediata de fármaco |
WO2013127831A1 (en) | 2012-02-28 | 2013-09-06 | Grünenthal GmbH | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
IN2014DN08122A (da) | 2012-03-06 | 2015-05-01 | Ferrosan Medical Devices As | |
MX362357B (es) | 2012-04-18 | 2019-01-14 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis. |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
RU2636240C2 (ru) | 2012-06-12 | 2017-11-21 | Ферросан Медикал Дивайсиз А/С | Сухая гемостатическая композиция |
CA2877183A1 (en) | 2012-07-06 | 2014-01-09 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
EP3003279A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
EP3003283A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
CA2912357C (en) | 2013-06-21 | 2019-12-31 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
JP6449871B2 (ja) | 2013-07-12 | 2019-01-09 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | エチレン−酢酸ビニルポリマーを含有する改変防止剤形 |
WO2015078891A1 (en) | 2013-11-26 | 2015-06-04 | Farmaceutici Formenti S.P.A. | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
US10111980B2 (en) | 2013-12-11 | 2018-10-30 | Ferrosan Medical Devices A/S | Dry composition comprising an extrusion enhancer |
CA2933983A1 (en) | 2013-12-16 | 2015-06-25 | Grunenthal Gmbh | Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion |
EP3106152B1 (en) * | 2014-02-12 | 2021-02-17 | Sawai Pharmaceutical Co., Ltd. | Orally disintegrating tablet coated with film |
CN106572980A (zh) | 2014-05-12 | 2017-04-19 | 格吕伦塔尔有限公司 | 包含他喷他多的防篡改即释胶囊制剂 |
EP3148512A1 (en) | 2014-05-26 | 2017-04-05 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
AU2015333206B2 (en) | 2014-10-13 | 2019-07-11 | Ferrosan Medical Devices A/S. | Dry composition for use in haemostasis and wound healing |
BR112017013565B1 (pt) | 2014-12-24 | 2021-12-28 | Ferrosan Medical Devices A/S | Seringa para retenção e mistura de primeira e segunda substâncias |
EP3285745A1 (en) | 2015-04-24 | 2018-02-28 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
BR112017027695A2 (pt) | 2015-07-03 | 2018-09-04 | Ferrosan Medical Devices As | seringa para retenção e mistura de primeira e segunda substâncias |
JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
WO2019215274A1 (en) | 2018-05-09 | 2019-11-14 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
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CA1018456A (en) | 1972-06-26 | 1977-10-04 | Hans Lowey | Prolonged release lozenges |
US4330338A (en) * | 1978-10-02 | 1982-05-18 | Purdue Research Foundation | Pharmaceutical coating composition, and preparation and dosages so coated |
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DE3320583A1 (de) * | 1983-06-08 | 1984-12-13 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung |
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ES2221370T3 (es) | 1998-04-03 | 2004-12-16 | Egalet A/S | Composicion de liberacion controlada. |
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IN191028B (da) | 2001-05-17 | 2003-09-13 | Sun Pharmaceutical Ind Ltd | |
DE60224293T2 (de) * | 2001-09-21 | 2008-12-11 | Egalet A/S | Feste dispersionen mit kontrollierter freisetzung von carvedilol |
US20040253310A1 (en) * | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
US20040234602A1 (en) * | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
BR0212946A (pt) * | 2001-09-28 | 2004-10-26 | Mcneil Ppc Inc | Formas de dosagens de liberação modificada |
WO2004041252A1 (en) * | 2002-11-08 | 2004-05-21 | Egalet A/S | Controlled release carvedilol compositions |
DE602004025159D1 (de) * | 2003-03-26 | 2010-03-04 | Egalet As | Matrixzubereitungen für die kontrollierte Darreichung von Arzneistoffen |
EP2301526B1 (en) * | 2003-03-26 | 2016-03-23 | Egalet Ltd. | Morphine controlled release system |
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-
1999
- 1999-03-25 ES ES99911627T patent/ES2221370T3/es not_active Expired - Lifetime
- 1999-03-25 JP JP2000541979A patent/JP4533531B2/ja not_active Expired - Fee Related
- 1999-03-25 AU AU30243/99A patent/AU3024399A/en not_active Abandoned
- 1999-03-25 CA CA002327685A patent/CA2327685C/en not_active Expired - Fee Related
- 1999-03-25 DE DE69917618T patent/DE69917618T2/de not_active Expired - Lifetime
- 1999-03-25 AT AT99911627T patent/ATE267589T1/de active
- 1999-03-25 EP EP99911627A patent/EP1067910B1/en not_active Expired - Lifetime
- 1999-03-25 DK DK99911627T patent/DK1067910T3/da active
- 1999-03-25 WO PCT/DK1999/000174 patent/WO1999051208A1/en active IP Right Grant
-
2004
- 2004-05-14 US US10/845,522 patent/US7883722B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1067910A1 (en) | 2001-01-17 |
DE69917618D1 (de) | 2004-07-01 |
CA2327685A1 (en) | 1999-10-14 |
ES2221370T3 (es) | 2004-12-16 |
ATE267589T1 (de) | 2004-06-15 |
AU3024399A (en) | 1999-10-25 |
WO1999051208A1 (en) | 1999-10-14 |
JP4533531B2 (ja) | 2010-09-01 |
US7883722B2 (en) | 2011-02-08 |
US20050089569A1 (en) | 2005-04-28 |
DE69917618T2 (de) | 2005-06-23 |
EP1067910B1 (en) | 2004-05-26 |
JP2002510616A (ja) | 2002-04-09 |
CA2327685C (en) | 2008-11-18 |
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