DE69901567T2 - Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs - Google Patents
Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffsInfo
- Publication number
- DE69901567T2 DE69901567T2 DE69901567T DE69901567T DE69901567T2 DE 69901567 T2 DE69901567 T2 DE 69901567T2 DE 69901567 T DE69901567 T DE 69901567T DE 69901567 T DE69901567 T DE 69901567T DE 69901567 T2 DE69901567 T2 DE 69901567T2
- Authority
- DE
- Germany
- Prior art keywords
- composition
- microemulsible
- formation
- polymeric matrix
- ingestion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9810313A FR2782006B1 (fr) | 1998-08-07 | 1998-08-07 | Composition a liberation prolongee apte a former une micro-emulsion |
PCT/FR1999/001889 WO2000007573A1 (fr) | 1998-08-07 | 1999-07-30 | Composition a liberation prolongee de principe actif apte a former une micro-emulsion |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69901567D1 DE69901567D1 (de) | 2002-06-27 |
DE69901567T2 true DE69901567T2 (de) | 2002-10-31 |
Family
ID=9529608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69901567T Expired - Lifetime DE69901567T2 (de) | 1998-08-07 | 1999-07-30 | Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs |
Country Status (10)
Country | Link |
---|---|
US (1) | US6309665B2 (de) |
EP (1) | EP1102581B1 (de) |
JP (1) | JP2002522379A (de) |
KR (1) | KR20010072292A (de) |
AT (1) | ATE217791T1 (de) |
AU (1) | AU5047099A (de) |
DE (1) | DE69901567T2 (de) |
ES (1) | ES2176001T3 (de) |
FR (1) | FR2782006B1 (de) |
WO (1) | WO2000007573A1 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008015299A1 (de) | 2008-03-18 | 2009-09-24 | Pkh Gmbh Halle | Kolloidales Trägersystem |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2838349B1 (fr) * | 2002-04-15 | 2004-06-25 | Laurence Paris | Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication |
DE10226990A1 (de) * | 2002-06-18 | 2004-03-18 | Sanguibiotech Ag | Topisch applizierbare Mikro-Emulsionen mit binärer Phasen- und Wirkstoffdifferenzierbarkeit, deren Herstellung und deren Verwendung, insbesondere zur Versorgung der Haut mit bioverfügbarem Sauerstoff |
GB0222612D0 (en) * | 2002-09-30 | 2002-11-06 | Univ Gent | Controlled delivery system for bioactive substances |
US20040115226A1 (en) * | 2002-12-12 | 2004-06-17 | Wenji Li | Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same |
US20070128117A1 (en) * | 2003-02-04 | 2007-06-07 | Bracco International B.V. | Ultrasound contrast agents and process for the preparation thereof |
US9364569B2 (en) | 2003-02-04 | 2016-06-14 | Bracco Suisse S.A. | Ultrasound contrast agents and process for the preparation thereof |
EP1701745B1 (de) | 2003-12-22 | 2014-12-10 | Bracco Suisse S.A. | Gasgefüllte mikrovesikel-anordnung für die kontrastdarstellung |
ES2425937T3 (es) * | 2004-03-24 | 2013-10-18 | Takeda Pharmaceutical Company Limited | Estabilizante de emulsión |
US20050220866A1 (en) * | 2004-04-02 | 2005-10-06 | Dr. Reddy's Laboratories Limited | Novel capsule formulations of etoposide for oral use |
WO2005105040A2 (en) * | 2004-04-26 | 2005-11-10 | Micelle Products, Inc. | Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications |
CA2575677C (en) | 2004-08-18 | 2013-01-22 | Bracco Research Sa | Gas-filled microvesicles composition for contrast imaging |
PT2985026T (pt) | 2005-04-15 | 2022-11-03 | Clarus Therapeutics Inc | Sistemas de distribuição farmacêuticos para fármacos hidrófobos e composições compreendendo os mesmos |
US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
US8293270B2 (en) * | 2005-10-26 | 2012-10-23 | Banner Pharmacaps, Inc. | Lipophilic vehicle-based dual controlled release matrix system |
US8333989B2 (en) * | 2005-10-26 | 2012-12-18 | Banner Pharmacaps, Inc. | Hydrophilic vehicle-based dual controlled release matrix system |
RS58017B1 (sr) | 2010-08-04 | 2019-02-28 | Gruenenthal Gmbh | Farmaceutska dozna forma koja sadrži 6'-fluoro-(n-metil- ili n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano[3,4,b]indol]-4-amin za lečenje nociceptivnog bola |
CN102846544B (zh) * | 2011-08-29 | 2014-01-15 | 华北制药集团新药研究开发有限责任公司 | 一种难溶药物的自微乳组合物 |
DE102012019029A1 (de) | 2012-09-27 | 2014-03-27 | Alf Lamprecht | Arzneiformulierungen zur oralen Gabe von therapeutischen Substanzen und Verfahren zur Herstellung |
US10245273B2 (en) | 2013-12-26 | 2019-04-02 | Clarus Therapeutics, Inc. | Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents |
US10245034B2 (en) * | 2015-08-31 | 2019-04-02 | Ethicon Llc | Inducing tissue adhesions using surgical adjuncts and medicants |
US10569071B2 (en) | 2015-08-31 | 2020-02-25 | Ethicon Llc | Medicant eluting adjuncts and methods of using medicant eluting adjuncts |
KR101679380B1 (ko) | 2015-09-10 | 2016-11-25 | 주식회사 유유제약 | 두타스테리드를 포함하는 약학적 조성물 및 이를 포함하는 캡슐 제형 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4797286A (en) * | 1985-11-12 | 1989-01-10 | Eli Lilly And Company | Orally administerable sustained release pharmaceutical formulations |
FR2629363B1 (fr) * | 1988-03-29 | 1991-10-11 | Rubinstein Inc H | Particules d'emulsion gelifiees et leur utilisation, notamment en cosmetologie |
GB9022788D0 (en) * | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
US5206219A (en) * | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
FR2710535B1 (fr) * | 1993-09-30 | 1995-11-24 | Gattefosse Ets Sa | Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion. |
US6054136A (en) * | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
US5545628A (en) * | 1995-01-10 | 1996-08-13 | Galephar P.R. Inc. | Pharmaceutical composition containing fenofibrate |
FR2748209B1 (fr) * | 1996-05-06 | 1998-06-05 | Adir | Composition pharmaceutique a base de matrices lipophiles stabilisees pour la liberation controlee de principes actifs |
US5993858A (en) * | 1996-06-14 | 1999-11-30 | Port Systems L.L.C. | Method and formulation for increasing the bioavailability of poorly water-soluble drugs |
BE1011363A3 (fr) * | 1997-09-11 | 1999-08-03 | Smb Technology | Capsules semi-solides autoemulsionnables matricielles a action prolongee. |
-
1998
- 1998-08-07 FR FR9810313A patent/FR2782006B1/fr not_active Expired - Fee Related
-
1999
- 1999-07-30 JP JP2000563259A patent/JP2002522379A/ja active Pending
- 1999-07-30 DE DE69901567T patent/DE69901567T2/de not_active Expired - Lifetime
- 1999-07-30 AT AT99934821T patent/ATE217791T1/de active
- 1999-07-30 AU AU50470/99A patent/AU5047099A/en not_active Abandoned
- 1999-07-30 WO PCT/FR1999/001889 patent/WO2000007573A1/fr not_active Application Discontinuation
- 1999-07-30 EP EP99934821A patent/EP1102581B1/de not_active Expired - Lifetime
- 1999-07-30 ES ES99934821T patent/ES2176001T3/es not_active Expired - Lifetime
- 1999-07-30 KR KR1020017001576A patent/KR20010072292A/ko not_active Application Discontinuation
-
2001
- 2001-02-02 US US09/775,782 patent/US6309665B2/en not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008015299A1 (de) | 2008-03-18 | 2009-09-24 | Pkh Gmbh Halle | Kolloidales Trägersystem |
EP2116229A1 (de) | 2008-03-18 | 2009-11-11 | PKH GmbH Halle | Kolloidales Trägersystem |
Also Published As
Publication number | Publication date |
---|---|
US6309665B2 (en) | 2001-10-30 |
FR2782006B1 (fr) | 2002-04-19 |
AU5047099A (en) | 2000-02-28 |
US20010004459A1 (en) | 2001-06-21 |
WO2000007573A1 (fr) | 2000-02-17 |
EP1102581B1 (de) | 2002-05-22 |
JP2002522379A (ja) | 2002-07-23 |
EP1102581A1 (de) | 2001-05-30 |
FR2782006A1 (fr) | 2000-02-11 |
ATE217791T1 (de) | 2002-06-15 |
DE69901567D1 (de) | 2002-06-27 |
KR20010072292A (ko) | 2001-07-31 |
ES2176001T3 (es) | 2002-11-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69901567D1 (de) | Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs | |
DK0951280T3 (da) | Hydrofile mikropartikler og fremgangsmåder til fremstilling heraf | |
AR018573A1 (es) | Metodo para microencapsular una sustancia solida y microcapsula de una sustancia solida que tiene una capa intermedia obtenida por el mismo | |
FR2767064B1 (fr) | Procede de liberation d'un principe actif contenu dans une emulsion multiple | |
NO20014859D0 (no) | Raskt dispergerbare doseringsformer inneholdende fiskegelatin | |
EP0967007A3 (de) | Verfahren zur Mikroverkapselung einer festen Substanz | |
EP1163902A3 (de) | Einen hydrophilen oder als Salz vorliegenden Arzneiwirkstoff enthaltende transdermale Zubereitung | |
NO992068L (no) | Mikroemulsjon og fremgangsmÕte for fremstilling av denne | |
ATE228822T1 (de) | Mikroemulsionen zur verwendung als träger zur verabreichung von wirkstoffen | |
ES2118677T1 (es) | Una composicion que comprende un agente activo disuelto en un vehiculo vitrificante y un procedimiento para su preparacion. | |
UY24210A1 (es) | Composicion de gel o de barra antitranspirante libre de pegajosidad, clara o translucida y metodo de fabricacion | |
ES551505A0 (es) | Un sistema osmotico lipidico para dispersar agentes farmacologicamente activos. | |
PT994727E (pt) | Processo para solubilizar ingredientes farmaceuticamente activos em agua e noutros veiculos aquosos | |
NO992908D0 (no) | Individuelt doserte folieformige administrasjonsformer som degraderer hurtig ved kontakt med vµsker og som inneholder virkestoff- og aromastoffer | |
DK1177081T3 (da) | En metode til at danne en mönstret betonoverflade | |
AU2002364979A1 (en) | Method for preparing a multiple water/oil/water emulsion | |
ES2108138T3 (es) | Matriz termocoloide controlada por la forma sol a base de gelatina para formas perorales de liberacion retardada. | |
ATE286388T1 (de) | Verfahren zur herstellung von nanokapseln des vesikulären typs | |
DE69923348D1 (de) | Transdermales arzneistoffverabreichungssystem | |
AR033979A1 (es) | Metodo para preparar un polipeptido il-18 fisiologicamente activo | |
AR034554A1 (es) | Un metodo para mejorar la distribucion de un ingrediente activo en un licor de curtido, una tableta o bloque para ser usado en dicho metodo, y el uso de dicha tableta o bloque en el curtido de cuero | |
WO2001076553A3 (en) | Method and device for enhanced transdermal drug delivery | |
JPS5517326A (en) | Creamy drug for external use, and its preparation | |
TW200722112A (en) | Microcapsule of polyvinyl alcohol copolymer | |
RU2000104807A (ru) | Способ управления активностью и стабильностью фермента |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |