ATE217791T1 - Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs - Google Patents

Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs

Info

Publication number
ATE217791T1
ATE217791T1 AT99934821T AT99934821T ATE217791T1 AT E217791 T1 ATE217791 T1 AT E217791T1 AT 99934821 T AT99934821 T AT 99934821T AT 99934821 T AT99934821 T AT 99934821T AT E217791 T1 ATE217791 T1 AT E217791T1
Authority
AT
Austria
Prior art keywords
microemulsion
forming
polymeric matrix
active ingredient
ingestion
Prior art date
Application number
AT99934821T
Other languages
English (en)
Inventor
Philippe Barthelemy
Hassan Benameur
Original Assignee
Gattefosse Holding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gattefosse Holding filed Critical Gattefosse Holding
Application granted granted Critical
Publication of ATE217791T1 publication Critical patent/ATE217791T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT99934821T 1998-08-07 1999-07-30 Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs ATE217791T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9810313A FR2782006B1 (fr) 1998-08-07 1998-08-07 Composition a liberation prolongee apte a former une micro-emulsion
PCT/FR1999/001889 WO2000007573A1 (fr) 1998-08-07 1999-07-30 Composition a liberation prolongee de principe actif apte a former une micro-emulsion

Publications (1)

Publication Number Publication Date
ATE217791T1 true ATE217791T1 (de) 2002-06-15

Family

ID=9529608

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99934821T ATE217791T1 (de) 1998-08-07 1999-07-30 Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs

Country Status (10)

Country Link
US (1) US6309665B2 (de)
EP (1) EP1102581B1 (de)
JP (1) JP2002522379A (de)
KR (1) KR20010072292A (de)
AT (1) ATE217791T1 (de)
AU (1) AU5047099A (de)
DE (1) DE69901567T2 (de)
ES (1) ES2176001T3 (de)
FR (1) FR2782006B1 (de)
WO (1) WO2000007573A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2838349B1 (fr) * 2002-04-15 2004-06-25 Laurence Paris Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
DE10226990A1 (de) * 2002-06-18 2004-03-18 Sanguibiotech Ag Topisch applizierbare Mikro-Emulsionen mit binärer Phasen- und Wirkstoffdifferenzierbarkeit, deren Herstellung und deren Verwendung, insbesondere zur Versorgung der Haut mit bioverfügbarem Sauerstoff
GB0222612D0 (en) * 2002-09-30 2002-11-06 Univ Gent Controlled delivery system for bioactive substances
US20040115226A1 (en) * 2002-12-12 2004-06-17 Wenji Li Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same
US9364569B2 (en) 2003-02-04 2016-06-14 Bracco Suisse S.A. Ultrasound contrast agents and process for the preparation thereof
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
WO2005063305A1 (en) * 2003-12-22 2005-07-14 Bracco Research Sa Gas-filled microvesicle assembly for contrast imaging
JP5057779B2 (ja) * 2004-03-24 2012-10-24 武田薬品工業株式会社 エマルション安定化製剤
US20050220866A1 (en) * 2004-04-02 2005-10-06 Dr. Reddy's Laboratories Limited Novel capsule formulations of etoposide for oral use
WO2005105040A2 (en) * 2004-04-26 2005-11-10 Micelle Products, Inc. Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications
EP1784228B1 (de) 2004-08-18 2016-10-05 Bracco Suisse SA Gasgefüllte mikrovesikelzusammensetzung für kontrastbilddarstellungen
CA2604943C (en) 2005-04-15 2013-09-17 Clarus Therapeutics, Inc. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
JP5406529B2 (ja) * 2005-10-26 2014-02-05 バナー ファーマキャプス， インコーポレイテッド カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム
CA2627292C (en) * 2005-10-26 2012-04-17 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
DE102008015299A1 (de) 2008-03-18 2009-09-24 Pkh Gmbh Halle Kolloidales Trägersystem
RU2631481C2 (ru) 2010-08-04 2017-09-22 Грюненталь Гмбх ЛЕКАРСТВЕННАЯ ДОЗИРОВАННАЯ ФОРМА, КОТОРАЯ СОДЕРЖИТ 6'-ФТОР-(N-МЕТИЛ-ИЛИ N, N-ДИМЕТИЛ-)-4-ФЕНИЛ-4', 9'-ДИГИДРО-3' Н-СПИРО[ЦИКЛОГЕКСАН-1, 1'-ПИРАНО[3, 4, b] ИНДОЛ]-4-АМИН ДЛЯ ЛЕЧЕНИЯ НОЦИЦЕПТИВНОЙ БОЛИ
CN102846544B (zh) * 2011-08-29 2014-01-15 华北制药集团新药研究开发有限责任公司 一种难溶药物的自微乳组合物
DE102012019029A1 (de) 2012-09-27 2014-03-27 Alf Lamprecht Arzneiformulierungen zur oralen Gabe von therapeutischen Substanzen und Verfahren zur Herstellung
WO2015100406A1 (en) 2013-12-26 2015-07-02 Clarus Therapeutics, Inc. Use of oral pharmaceutical products combining testosterone esters with hypolipidemic agents
US10245034B2 (en) * 2015-08-31 2019-04-02 Ethicon Llc Inducing tissue adhesions using surgical adjuncts and medicants
US10569071B2 (en) 2015-08-31 2020-02-25 Ethicon Llc Medicant eluting adjuncts and methods of using medicant eluting adjuncts
KR101679380B1 (ko) 2015-09-10 2016-11-25 주식회사 유유제약 두타스테리드를 포함하는 약학적 조성물 및 이를 포함하는 캡슐 제형

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797286A (en) * 1985-11-12 1989-01-10 Eli Lilly And Company Orally administerable sustained release pharmaceutical formulations
FR2629363B1 (fr) * 1988-03-29 1991-10-11 Rubinstein Inc H Particules d'emulsion gelifiees et leur utilisation, notamment en cosmetologie
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments
FR2710535B1 (fr) * 1993-09-30 1995-11-24 Gattefosse Ets Sa Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion.
US6054136A (en) * 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5545628A (en) * 1995-01-10 1996-08-13 Galephar P.R. Inc. Pharmaceutical composition containing fenofibrate
FR2748209B1 (fr) * 1996-05-06 1998-06-05 Adir Composition pharmaceutique a base de matrices lipophiles stabilisees pour la liberation controlee de principes actifs
US5993858A (en) * 1996-06-14 1999-11-30 Port Systems L.L.C. Method and formulation for increasing the bioavailability of poorly water-soluble drugs
BE1011363A3 (fr) * 1997-09-11 1999-08-03 Smb Technology Capsules semi-solides autoemulsionnables matricielles a action prolongee.

Also Published As

Publication number Publication date
WO2000007573A1 (fr) 2000-02-17
FR2782006B1 (fr) 2002-04-19
KR20010072292A (ko) 2001-07-31
JP2002522379A (ja) 2002-07-23
AU5047099A (en) 2000-02-28
EP1102581A1 (de) 2001-05-30
EP1102581B1 (de) 2002-05-22
ES2176001T3 (es) 2002-11-16
US6309665B2 (en) 2001-10-30
FR2782006A1 (fr) 2000-02-11
US20010004459A1 (en) 2001-06-21
DE69901567T2 (de) 2002-10-31
DE69901567D1 (de) 2002-06-27

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