KR950007808A - 약물투여용 의료용구 - Google Patents
약물투여용 의료용구 Download PDFInfo
- Publication number
- KR950007808A KR950007808A KR1019940020906A KR19940020906A KR950007808A KR 950007808 A KR950007808 A KR 950007808A KR 1019940020906 A KR1019940020906 A KR 1019940020906A KR 19940020906 A KR19940020906 A KR 19940020906A KR 950007808 A KR950007808 A KR 950007808A
- Authority
- KR
- South Korea
- Prior art keywords
- drug
- gel
- medical device
- drug administration
- patch
- Prior art date
Links
- 238000001647 drug administration Methods 0.000 title claims 3
- 239000003814 drug Substances 0.000 claims abstract 7
- 229940079593 drug Drugs 0.000 claims abstract 7
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- 239000012790 adhesive layer Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000012982 microporous membrane Substances 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000001632 homeopathic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
본 발명은 극소량의 약물 또는 극소량의 유효성분, 특히 동종요법 약물(Homeopathic drugs)의 투여용 의료용구에 관한 것이다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 경피투여 패치의 단면도이다.
Claims (2)
- 극소량의 약물 또는 유효성분을 투여하기 위한 약물투여용 의료용구에 있어서, (가) 피부에 도포시키는 패치의 외피에 해당하는 지지막(1)과; (나)패치의 부착을 위한 접촉면으로서 패치 외피의 반대편에 위치하는 다공성 접작층(3)과; (다)지지막(1)과 다공성 접착층(3) 사이에 있으면서 약물의 방출을 조절하는 미세기공막(2)및; (라)투여하고자 하는 동중요법 약물(5)이 분산되어 있는 겔(6)로 이루어져 있되; 상기 미세기공막(2)의 상부에는 약물 저장고 역할을 겔영역(6a)이 있고, 그 하부는 상부 겔영역(6a)보다 약물 농도가 낮은 겔영역(6b)으로 이루어져 있는 것을 특징으로 하는 약물투여용 의료용구.
- 제1항에 있어서, 상기 겔(6)은 글리세린, 증류수, 락토스, 폴리(비닐알콜), 폴리(비닐-2-피롤리돈) 및 시트르산 나트륨으로 이루어져 있는 것을 특징으로 하는 약물투여용 의료용구.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM93A000591 | 1993-09-02 | ||
ITRM930591A IT1261849B (it) | 1993-09-02 | 1993-09-02 | Dispositivo medico per la somministrazione di principi attivi o farmaci a bassissimo dosaggio, in particolare di farmaci omeopatici. |
Publications (1)
Publication Number | Publication Date |
---|---|
KR950007808A true KR950007808A (ko) | 1995-04-15 |
Family
ID=11401933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940020906A KR950007808A (ko) | 1993-09-02 | 1994-08-24 | 약물투여용 의료용구 |
Country Status (12)
Country | Link |
---|---|
US (1) | US5683712A (ko) |
EP (1) | EP0641561B1 (ko) |
JP (1) | JPH07165566A (ko) |
KR (1) | KR950007808A (ko) |
AT (1) | ATE173162T1 (ko) |
CA (1) | CA2129760A1 (ko) |
DE (1) | DE69414502T2 (ko) |
DK (1) | DK0641561T3 (ko) |
ES (1) | ES2125380T3 (ko) |
GR (1) | GR3029308T3 (ko) |
IT (1) | IT1261849B (ko) |
ZA (1) | ZA946698B (ko) |
Families Citing this family (49)
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US6475514B1 (en) | 1998-12-03 | 2002-11-05 | Andrew Blitzer | Athletic patch |
GB2354636A (en) * | 1999-09-25 | 2001-03-28 | Ibm | Mounting chips on substrates |
FR2806910B1 (fr) * | 2000-04-03 | 2003-01-24 | Dolisos Lab | Procede d'inactivation virale de solutions hydro-alcooliques |
RU2181297C2 (ru) | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
US20030022206A1 (en) * | 2001-05-16 | 2003-01-30 | Kay Robert A. | Method of characterizing a homeopathic preparation |
US20040009180A1 (en) * | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
UA76641C2 (uk) * | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Гомеопатичний лікарський засіб та спосіб лікування захворювань передміхурової залози |
UA76639C2 (uk) * | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Гомеопатичний лікарський засіб та спосіб лікування еректильних дисфункцій |
UA76638C2 (en) * | 2002-08-02 | 2006-08-15 | Oleh Illich Epshtein | Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon |
UA76640C2 (uk) * | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Спосіб корекції патологічних імунних реакцій та гомеопатичний лікарський засіб |
US20050255139A1 (en) * | 2004-05-14 | 2005-11-17 | Hurd Jonathan L | Polymeric compositions with embedded pesticidal desiccants |
US20060188558A1 (en) * | 2005-02-18 | 2006-08-24 | Mylan Technologies, Inc. | Transdermal systems having control delivery system |
US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
TR201901443T4 (tr) | 2005-12-01 | 2019-02-21 | Univ Massachusetts Lowell | Botulinum nanoemülsiyonları. |
RU2309732C1 (ru) * | 2006-03-13 | 2007-11-10 | Олег Ильич Эпштейн | Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата |
WO2008039245A2 (en) | 2006-04-27 | 2008-04-03 | Anterios, Inc. | Assessment of the effects of topical administration of chemodenervating pharmaceuticals |
JP5687425B2 (ja) * | 2006-06-06 | 2015-03-18 | オレグ イリッチ エプシュテイン | 肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤 |
BRPI0719732A2 (pt) | 2006-12-01 | 2017-05-16 | Anterios Inc | nanopartículas de peptídeo e usos para as mesmas |
EP2494958A1 (en) | 2006-12-01 | 2012-09-05 | Anterios, Inc. | Amphiphilic Entity Nanoparticles |
US8940326B2 (en) | 2007-03-19 | 2015-01-27 | Vita Sciences Llc | Transdermal patch and method for delivery of vitamin B12 |
ES2660906T3 (es) | 2007-05-31 | 2018-03-26 | Anterios, Inc. | Nanopartículas de ácido nucleico y usos de las mismas |
US20090047334A1 (en) * | 2007-08-13 | 2009-02-19 | Patricia Williams | Transdermal patch for extended delivery of calcium |
WO2009158687A1 (en) | 2008-06-26 | 2009-12-30 | Anterios, Inc. | Dermal delivery |
KR101901465B1 (ko) | 2010-07-15 | 2018-09-21 | 올레그 일리치 엡쉬테인 | 위장관의 기능적 질환 또는 상태를 치료하는 제약학적 복합 조성물 및 방법들 |
CN103154028A (zh) | 2010-07-15 | 2013-06-12 | 奥列格·伊里奇·爱泼斯坦 | 复合药物组合物以及对神经退行性疾病相关的疾病或病症进行治疗的方法 |
SG187038A1 (en) | 2010-07-15 | 2013-02-28 | Oleg Iliich Epshtein | A method of increasing the effect of an activated-potentiated form of an antibody |
JP6158082B2 (ja) | 2010-07-17 | 2017-07-05 | メルク パテント ゲーエムベーハー | 浸透と作用の増強 |
UA112755C2 (uk) | 2010-07-21 | 2016-10-25 | Олєг Ільіч Епштейн | Метод лікування синдрому дефіциту уваги і гіперактивності |
CA2805978C (en) | 2010-07-21 | 2016-06-28 | Oleg Iliich Epshtein | Combination pharmaceutical composition and methods of treating diseases or conditions associated with respiratory disease or condition |
AU2012209274A1 (en) | 2011-01-24 | 2013-09-12 | Anterios, Inc. | Nanoparticle compositions, formulations thereof, and uses therefor |
US20120328549A1 (en) | 2011-01-24 | 2012-12-27 | Anterios, Inc. | Oil compositions |
KR20140003572A (ko) | 2011-01-24 | 2014-01-09 | 안테리오스, 인코퍼레이티드 | 나노입자 조성물 |
US20120225018A1 (en) * | 2011-03-03 | 2012-09-06 | Nancy Josephine Polich | Homeopathic therapeutic method and compositions |
US10022335B2 (en) | 2011-03-03 | 2018-07-17 | Nancy Josephine Polich | Homeopathic therapeutic method and compositions |
PT2683385T (pt) | 2011-03-10 | 2018-10-19 | Rigel Pharmaceuticals Inc | Pirimidinadiaminas 2,4-substituídas para utilização no lúpus discoide |
WO2012129519A1 (en) | 2011-03-23 | 2012-09-27 | Deseret Biologicals, Inc. | Formulations of diluted amino acid segments and methods for making same |
BE1020027A3 (fr) | 2011-06-23 | 2013-04-02 | Jean Pierre Mageren | Compositions homeopathiques pour le traitement des douleurs du dos et des sciatiques. |
WO2013163176A1 (en) | 2012-04-23 | 2013-10-31 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
KR101365321B1 (ko) * | 2012-05-22 | 2014-02-20 | 제일약품주식회사 | 매트릭스내 비스테로이드성 소염진통제의 농도구배를 이용하여 경피투과도를 향상시킨 패취제 |
WO2014043257A1 (en) | 2012-09-12 | 2014-03-20 | Rigel Pharmaceuticals, Inc. | Treatment for vitiligo |
JP2016516754A (ja) | 2013-04-03 | 2016-06-09 | アラーテイン・セラピューティクス・リミテッド・ライアビリティ・カンパニーAllertein Therapeutics, LLC | 新規のナノ粒子組成物 |
WO2015168564A1 (en) | 2014-05-01 | 2015-11-05 | Anterios, Inc. | Methods to treat, prevent, and improve skin conditions |
CA2993288A1 (en) | 2015-07-24 | 2017-02-02 | Glaxo Group Limited | Treatment for vitiligo |
KR102487144B1 (ko) | 2016-11-21 | 2023-01-12 | 에이리온 테라퓨틱스, 인코포레이티드 | 큰 물질의 경피 전달 |
CN112351992A (zh) | 2017-12-20 | 2021-02-09 | 阿勒根公司 | 肉毒杆菌毒素细胞结合结构域多肽及其用于皮肤再生的方法 |
WO2020056191A1 (en) | 2018-09-13 | 2020-03-19 | Eirion Therapeutics, Inc. | Uses of plasminogen activator inhibitor 1 (pai-1) inhibitors |
WO2020056160A1 (en) | 2018-09-13 | 2020-03-19 | Eirion Therapeutics, Inc. | Plasminogen activator inhibitor 1 (pai-1) inhibitors and uses therefor |
AU2019391791A1 (en) | 2018-12-03 | 2021-06-03 | Eirion Therapeutics, Inc. | Improved delivery of large agents |
BR112021022619A2 (pt) | 2019-05-14 | 2022-01-04 | Eirion Therapeutics Inc | Retardo de efeito de pico e/ou prolongamento de duração de resposta |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US4060084A (en) * | 1976-09-07 | 1977-11-29 | Alza Corporation | Method and therapeutic system for providing chemotherapy transdermally |
US4605548A (en) * | 1983-05-31 | 1986-08-12 | Nitto Electric Industrial Co., Ltd. | Drug administration material |
US4788064A (en) * | 1987-07-31 | 1988-11-29 | Warner-Lambert Company | Transdermal delivery system |
WO1992006701A1 (en) * | 1990-10-18 | 1992-04-30 | Huffstutler, M., Conrad, Jr. | Preparation of concentrated fluid symphytum extracts, therapeutic forms and methods of use |
-
1993
- 1993-09-02 IT ITRM930591A patent/IT1261849B/it active IP Right Grant
-
1994
- 1994-08-02 AT AT94112012T patent/ATE173162T1/de not_active IP Right Cessation
- 1994-08-02 ES ES94112012T patent/ES2125380T3/es not_active Expired - Lifetime
- 1994-08-02 EP EP94112012A patent/EP0641561B1/en not_active Expired - Lifetime
- 1994-08-02 DK DK94112012T patent/DK0641561T3/da active
- 1994-08-02 DE DE69414502T patent/DE69414502T2/de not_active Expired - Fee Related
- 1994-08-09 CA CA002129760A patent/CA2129760A1/en not_active Abandoned
- 1994-08-24 KR KR1019940020906A patent/KR950007808A/ko not_active IP Right Cessation
- 1994-09-01 ZA ZA946698A patent/ZA946698B/xx unknown
- 1994-09-02 JP JP6209599A patent/JPH07165566A/ja active Pending
-
1995
- 1995-09-14 US US08/528,162 patent/US5683712A/en not_active Expired - Fee Related
-
1999
- 1999-02-05 GR GR990400390T patent/GR3029308T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA946698B (en) | 1995-05-02 |
JPH07165566A (ja) | 1995-06-27 |
CA2129760A1 (en) | 1995-03-03 |
US5683712A (en) | 1997-11-04 |
DE69414502D1 (de) | 1998-12-17 |
IT1261849B (it) | 1996-06-03 |
EP0641561B1 (en) | 1998-11-11 |
ITRM930591A1 (it) | 1995-03-02 |
GR3029308T3 (en) | 1999-05-28 |
DK0641561T3 (da) | 1999-07-26 |
ITRM930591A0 (it) | 1993-09-02 |
EP0641561A3 (en) | 1995-09-27 |
EP0641561A2 (en) | 1995-03-08 |
ATE173162T1 (de) | 1998-11-15 |
DE69414502T2 (de) | 1999-04-08 |
ES2125380T3 (es) | 1999-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
SUBM | Surrender of laid-open application requested |