DE69901567D1 - Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs - Google Patents

Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs

Info

Publication number
DE69901567D1
DE69901567D1 DE69901567T DE69901567T DE69901567D1 DE 69901567 D1 DE69901567 D1 DE 69901567D1 DE 69901567 T DE69901567 T DE 69901567T DE 69901567 T DE69901567 T DE 69901567T DE 69901567 D1 DE69901567 D1 DE 69901567D1
Authority
DE
Germany
Prior art keywords
composition
microemulsible
formation
polymeric matrix
ingestion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69901567T
Other languages
English (en)
Other versions
DE69901567T2 (de
Inventor
Philippe Barthelemy
Hassan Benameur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GATTEFOSSE HOLDING SAINT PRIES
Original Assignee
GATTEFOSSE HOLDING SAINT PRIES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GATTEFOSSE HOLDING SAINT PRIES filed Critical GATTEFOSSE HOLDING SAINT PRIES
Publication of DE69901567D1 publication Critical patent/DE69901567D1/de
Application granted granted Critical
Publication of DE69901567T2 publication Critical patent/DE69901567T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69901567T 1998-08-07 1999-07-30 Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs Expired - Lifetime DE69901567T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9810313A FR2782006B1 (fr) 1998-08-07 1998-08-07 Composition a liberation prolongee apte a former une micro-emulsion
PCT/FR1999/001889 WO2000007573A1 (fr) 1998-08-07 1999-07-30 Composition a liberation prolongee de principe actif apte a former une micro-emulsion

Publications (2)

Publication Number Publication Date
DE69901567D1 true DE69901567D1 (de) 2002-06-27
DE69901567T2 DE69901567T2 (de) 2002-10-31

Family

ID=9529608

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69901567T Expired - Lifetime DE69901567T2 (de) 1998-08-07 1999-07-30 Zur bildung einer mikroemulsion fähigen zusammensetzung mit verlängerter freisetzung des wirkstoffs

Country Status (10)

Country Link
US (1) US6309665B2 (de)
EP (1) EP1102581B1 (de)
JP (1) JP2002522379A (de)
KR (1) KR20010072292A (de)
AT (1) ATE217791T1 (de)
AU (1) AU5047099A (de)
DE (1) DE69901567T2 (de)
ES (1) ES2176001T3 (de)
FR (1) FR2782006B1 (de)
WO (1) WO2000007573A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2838349B1 (fr) * 2002-04-15 2004-06-25 Laurence Paris Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
DE10226990A1 (de) * 2002-06-18 2004-03-18 Sanguibiotech Ag Topisch applizierbare Mikro-Emulsionen mit binärer Phasen- und Wirkstoffdifferenzierbarkeit, deren Herstellung und deren Verwendung, insbesondere zur Versorgung der Haut mit bioverfügbarem Sauerstoff
GB0222612D0 (en) * 2002-09-30 2002-11-06 Univ Gent Controlled delivery system for bioactive substances
US20040115226A1 (en) * 2002-12-12 2004-06-17 Wenji Li Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
US9364569B2 (en) 2003-02-04 2016-06-14 Bracco Suisse S.A. Ultrasound contrast agents and process for the preparation thereof
CA2547024C (en) * 2003-12-22 2013-12-17 Bracco Research Sa Gas-filled microvesicle assembly for contrast imaging
US20080249147A1 (en) * 2004-03-24 2008-10-09 Takeda Pharmaceutical Company Limited Emulsion-Stabilized Preparation
US20050220866A1 (en) * 2004-04-02 2005-10-06 Dr. Reddy's Laboratories Limited Novel capsule formulations of etoposide for oral use
US20050238675A1 (en) * 2004-04-26 2005-10-27 Wenjie Li Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications
WO2006018433A1 (en) 2004-08-18 2006-02-23 Bracco Research Sa Gas-filled microvesicles composition for contrast imaging
EP2985026B1 (de) 2005-04-15 2022-08-03 Clarus Therapeutics, Inc. Systeme zur pharmazeutischen verabreichung hydrophober wirkstoffe und zusammensetzungen damit
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
US8333989B2 (en) * 2005-10-26 2012-12-18 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
JP5406529B2 (ja) * 2005-10-26 2014-02-05 バナー ファーマキャプス， インコーポレイテッド カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム
DE102008015299A1 (de) 2008-03-18 2009-09-24 Pkh Gmbh Halle Kolloidales Trägersystem
ES2675316T3 (es) 2010-08-04 2018-07-10 Grünenthal GmbH Dosificación farmacéutica que comprende 6'-fluoro-(n-metil- o n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-espiro[ciclohexano-1,1'-pirano[3,4,b]indol]-4-amina para el tratamiento del dolor neuropático
CN102846544B (zh) * 2011-08-29 2014-01-15 华北制药集团新药研究开发有限责任公司 一种难溶药物的自微乳组合物
DE102012019029A1 (de) 2012-09-27 2014-03-27 Alf Lamprecht Arzneiformulierungen zur oralen Gabe von therapeutischen Substanzen und Verfahren zur Herstellung
US10245273B2 (en) 2013-12-26 2019-04-02 Clarus Therapeutics, Inc. Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents
US10245034B2 (en) * 2015-08-31 2019-04-02 Ethicon Llc Inducing tissue adhesions using surgical adjuncts and medicants
US10569071B2 (en) 2015-08-31 2020-02-25 Ethicon Llc Medicant eluting adjuncts and methods of using medicant eluting adjuncts
KR101679380B1 (ko) * 2015-09-10 2016-11-25 주식회사 유유제약 두타스테리드를 포함하는 약학적 조성물 및 이를 포함하는 캡슐 제형
WO2024142045A1 (en) * 2022-12-28 2024-07-04 Bsd Science Ltd. Controlled-release oral formulations of lipophilic drugs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797286A (en) * 1985-11-12 1989-01-10 Eli Lilly And Company Orally administerable sustained release pharmaceutical formulations
FR2629363B1 (fr) * 1988-03-29 1991-10-11 Rubinstein Inc H Particules d'emulsion gelifiees et leur utilisation, notamment en cosmetologie
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments
US6054136A (en) * 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
FR2710535B1 (fr) * 1993-09-30 1995-11-24 Gattefosse Ets Sa Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion.
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5545628A (en) * 1995-01-10 1996-08-13 Galephar P.R. Inc. Pharmaceutical composition containing fenofibrate
FR2748209B1 (fr) * 1996-05-06 1998-06-05 Adir Composition pharmaceutique a base de matrices lipophiles stabilisees pour la liberation controlee de principes actifs
US5993858A (en) * 1996-06-14 1999-11-30 Port Systems L.L.C. Method and formulation for increasing the bioavailability of poorly water-soluble drugs
BE1011363A3 (fr) * 1997-09-11 1999-08-03 Smb Technology Capsules semi-solides autoemulsionnables matricielles a action prolongee.

Also Published As

Publication number Publication date
WO2000007573A1 (fr) 2000-02-17
AU5047099A (en) 2000-02-28
EP1102581A1 (de) 2001-05-30
ATE217791T1 (de) 2002-06-15
JP2002522379A (ja) 2002-07-23
US6309665B2 (en) 2001-10-30
FR2782006A1 (fr) 2000-02-11
US20010004459A1 (en) 2001-06-21
FR2782006B1 (fr) 2002-04-19
KR20010072292A (ko) 2001-07-31
EP1102581B1 (de) 2002-05-22
DE69901567T2 (de) 2002-10-31
ES2176001T3 (es) 2002-11-16

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