PT994727E - Processo para solubilizar ingredientes farmaceuticamente activos em agua e noutros veiculos aquosos - Google Patents

Processo para solubilizar ingredientes farmaceuticamente activos em agua e noutros veiculos aquosos

Info

Publication number
PT994727E
PT994727E PT98937757T PT98937757T PT994727E PT 994727 E PT994727 E PT 994727E PT 98937757 T PT98937757 T PT 98937757T PT 98937757 T PT98937757 T PT 98937757T PT 994727 E PT994727 E PT 994727E
Authority
PT
Portugal
Prior art keywords
water
pharmaceutically active
complex
aqueous vehicles
solubilizing
Prior art date
Application number
PT98937757T
Other languages
English (en)
Inventor
Marco Fabrizio Saettone
Boris Giannaccini
Enrico Boldrini
Pietro Bianchini
Original Assignee
Farmigea Spa
Marco Fabrizio Saettone
Boris Giannaccini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmigea Spa, Marco Fabrizio Saettone, Boris Giannaccini filed Critical Farmigea Spa
Publication of PT994727E publication Critical patent/PT994727E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
PT98937757T 1997-07-23 1998-07-22 Processo para solubilizar ingredientes farmaceuticamente activos em agua e noutros veiculos aquosos PT994727E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000456A IT1294205B1 (it) 1997-07-23 1997-07-23 Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive

Publications (1)

Publication Number Publication Date
PT994727E true PT994727E (pt) 2003-03-31

Family

ID=11405192

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98937757T PT994727E (pt) 1997-07-23 1998-07-22 Processo para solubilizar ingredientes farmaceuticamente activos em agua e noutros veiculos aquosos

Country Status (11)

Country Link
US (1) US6346273B1 (pt)
EP (1) EP0994727B1 (pt)
JP (1) JP2001510810A (pt)
AT (1) ATE226451T1 (pt)
AU (1) AU8645098A (pt)
DE (1) DE69808911T2 (pt)
EA (1) EA002326B1 (pt)
ES (1) ES2186197T3 (pt)
IT (1) IT1294205B1 (pt)
PT (1) PT994727E (pt)
WO (1) WO1999004823A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19845305A1 (de) * 1998-10-01 2000-04-06 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Flavonen, Flavanonen bzw. Flavonoiden, synergistische Gemische aus Flavonen, Flavanonen bzw. Flavonoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
AU2001269672A1 (en) * 2000-10-05 2002-04-15 Unimed Pharma Spol. S.R.O. Eye instillation with decongestant effect
US6866396B2 (en) * 2002-10-09 2005-03-15 Jji Lighting Group, Inc. Illuminating device with rotatably adjustable support
US20040115226A1 (en) * 2002-12-12 2004-06-17 Wenji Li Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same
SG178721A1 (en) * 2003-07-29 2012-03-29 Signature R & D Holdings Llc Amino acid prodrugs
US6960300B2 (en) * 2003-09-08 2005-11-01 Sami Labs Limited Process for preparing water soluble diterpenes and their applications
US20050238675A1 (en) * 2004-04-26 2005-10-27 Wenjie Li Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications
WO2006007354A2 (en) * 2004-06-28 2006-01-19 Alza Corporation A drug/polymer complex, preferably ciprofloxacin/hpmc, its method of manufacturing using lyophilization and its use in an osmotic device
US20100260691A1 (en) * 2006-07-31 2010-10-14 Narayanan Kolazi S Aqueous compositions containing a hydrophobic material
US20100239629A1 (en) * 2006-07-31 2010-09-23 Isp Investments Inc. Delivery system for delivering bioactive materials
KR101667534B1 (ko) 2006-09-22 2016-10-19 씨아이피엘에이 엘티디. 리팍시민
US8747871B2 (en) * 2006-09-28 2014-06-10 Isp Investments Inc. Synergistic matrix composite for making stable microemulsions of active ingredients
US9717584B2 (en) * 2007-04-13 2017-08-01 W. L. Gore & Associates, Inc. Medical apparatus and method of making the same
CA2745980C (en) * 2008-12-10 2017-10-31 Cipla Limited Rifaximin complexes
RU2523562C1 (ru) * 2013-05-23 2014-07-20 Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) Способ получения таблеток рутина
US9814560B2 (en) 2013-12-05 2017-11-14 W. L. Gore & Associates, Inc. Tapered implantable device and methods for making such devices
AU2016270380B2 (en) 2015-06-05 2019-04-04 W. L. Gore & Associates, Inc. A low bleed implantable prosthesis with a taper
WO2017103840A1 (en) * 2015-12-16 2017-06-22 MOHAMED ABDULLA ANZAR, Cheppattu A water soluble 10% w/w forskolin composition and a method of synthesizing the same
DK3565602T3 (da) * 2017-01-09 2021-06-07 Scipharm S A R L Hidtil ukendt fremgangsmåde til fremstilling af vandopløselig forskolin
JP6506787B2 (ja) 2017-03-06 2019-04-24 ストローブ株式会社 成膜方法
DK4093374T3 (da) 2020-01-23 2024-02-05 Scipharm Sarl Kompleks af 7-deacetylforskolin og PVP
KR20220149987A (ko) * 2021-05-03 2022-11-10 연세대학교 산학협력단 안구건조증 또는 안구건조증 연관 안과 질환의 예방, 개선 또는 치료용 조성물
WO2023027670A2 (en) * 2021-08-23 2023-03-02 Tum Ekip Ilac Anonim Sirketi Lyophilized levosimendan compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883785A (en) * 1984-07-27 1989-11-28 Chow Wing Sun Complex of anti-fungal agent and cyclodextrin and method
US4900775A (en) * 1988-02-29 1990-02-13 Gaf Chemicals Corporation Solubilization of complexes of water-insoluble organic compounds by aqueous solutions of polyvinylpyrrolidone
AU5036590A (en) 1989-02-24 1990-09-26 Gaf Chemicals Corporation Solubilization of indomethacin and piroxicam by a quaternized polymer
IL89530A0 (en) 1989-03-08 1989-09-10 Jeffrey J Feigenbaum Compositions containing forskolin
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
AU2531295A (en) 1994-05-27 1995-12-21 Farmarc Nederland Bv Pharmaceutical composition
IL131609A0 (en) * 1997-03-12 2001-01-28 Abbott Lab Hydrophilic binary systems for the administration of cyclosporine

Also Published As

Publication number Publication date
EA002326B1 (ru) 2002-04-25
ES2186197T3 (es) 2003-05-01
EP0994727B1 (en) 2002-10-23
JP2001510810A (ja) 2001-08-07
ITRM970456A1 (it) 1999-01-23
ITRM970456A0 (pt) 1997-07-23
DE69808911D1 (de) 2002-11-28
ATE226451T1 (de) 2002-11-15
EA200000154A1 (ru) 2000-10-30
AU8645098A (en) 1999-02-16
IT1294205B1 (it) 1999-03-24
WO1999004823A1 (en) 1999-02-04
EP0994727A1 (en) 2000-04-26
US6346273B1 (en) 2002-02-12
DE69808911T2 (de) 2003-06-12

Similar Documents

Publication Publication Date Title
PT994727E (pt) Processo para solubilizar ingredientes farmaceuticamente activos em agua e noutros veiculos aquosos
NO971898D0 (no) Farmasöytiske preparater
ES2110377T1 (es) Formulacion galenica de fenofibrato y aplicacion de la misma.
CY1114631T1 (el) Φαρμακοτεχνικες μορφες εχινοκανδινης που περιεχουν επιφανειοδραστικα που σχηματιζουν μικκυλιο
ATE554750T1 (de) Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen
DE60023465D1 (de) Pharmazeutische formulierungen mit verbesserter löslichkeit in wasser
BR9912975A (pt) Composto e composições para liberação de agentes ativos, método para sua obtenção e seu uso
DE69812343D1 (de) Feste pharmazeutische formulierungen enthaltend eine physische mischung aus sulphoalkylethercyclodextrin und einem therapeutischen wirkstoff
HUP0200114A2 (hu) Bioaktív komplexek kapszulázása liposzómákba
KR970061270A (ko) 히토성장호르몬을 함유하는 의약제제
EE200000466A (et) Omeprasooli mikrograanulid, nende valmistamismeetod ja farmatseutilised preparaadid
NO974868L (no) Preparater omfattende lipofile forbindelser
AU5047099A (en) Composition with prolonged release of active principle capable of forming a micro-emulsion
BRPI0413957A (pt) processo para preparar diterpenos solúveis em água, solução aquosa e suas aplicações
CA2426852A1 (en) Formulation containing phosphate derivatives of electron transfer agents
ES2179103T3 (es) Composicion detergente.
IT1314185B1 (it) Composizione farmaceutica per somministrazione di sostanze attivescarsamente solubili in mezzi acquosi
ES2137635T3 (es) Composicion liquida estable que contiene urato oxidasa y composicion liofilizada para su preparacion.
BR9611343A (pt) Processo de solubilização d eum agente em um anfifìlico, composição, e, uso da mesma.
PT90991A (pt) Processo para a preparacao de composicoes pesticidas em pastilhas
SE9902742D0 (sv) New pharmaceutical formultion
TH41442A (th) ระบบตัวทำละลายสำหรับทำให้สารประกอบทางเภสัชแทรกซึมได้มากขึ้น
TH40972A3 (th) สารประกอบอินทรีย์