DK3565602T3 - Hidtil ukendt fremgangsmåde til fremstilling af vandopløselig forskolin - Google Patents

Hidtil ukendt fremgangsmåde til fremstilling af vandopløselig forskolin Download PDF

Info

Publication number
DK3565602T3
DK3565602T3 DK18700143.3T DK18700143T DK3565602T3 DK 3565602 T3 DK3565602 T3 DK 3565602T3 DK 18700143 T DK18700143 T DK 18700143T DK 3565602 T3 DK3565602 T3 DK 3565602T3
Authority
DK
Denmark
Prior art keywords
novel method
producing water
soluble forskolin
forskolin
soluble
Prior art date
Application number
DK18700143.3T
Other languages
English (en)
Inventor
Andreas Kubin
Original Assignee
Scipharm S A R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scipharm S A R L filed Critical Scipharm S A R L
Application granted granted Critical
Publication of DK3565602T3 publication Critical patent/DK3565602T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
DK18700143.3T 2017-01-09 2018-01-09 Hidtil ukendt fremgangsmåde til fremstilling af vandopløselig forskolin DK3565602T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17150644 2017-01-09
PCT/EP2018/050447 WO2018127600A1 (en) 2017-01-09 2018-01-09 Novel process for preparing water soluble forskolin

Publications (1)

Publication Number Publication Date
DK3565602T3 true DK3565602T3 (da) 2021-06-07

Family

ID=57868023

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18700143.3T DK3565602T3 (da) 2017-01-09 2018-01-09 Hidtil ukendt fremgangsmåde til fremstilling af vandopløselig forskolin

Country Status (17)

Country Link
US (1) US11234957B2 (da)
EP (1) EP3565602B1 (da)
JP (1) JP7138643B2 (da)
KR (1) KR102583356B1 (da)
CN (1) CN110325217B (da)
CY (1) CY1124325T1 (da)
DK (1) DK3565602T3 (da)
ES (1) ES2872223T3 (da)
HR (1) HRP20210863T1 (da)
HU (1) HUE054617T2 (da)
LT (1) LT3565602T (da)
PL (1) PL3565602T3 (da)
PT (1) PT3565602T (da)
RS (1) RS61915B1 (da)
SG (1) SG11201906321WA (da)
SI (1) SI3565602T1 (da)
WO (1) WO2018127600A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI4093374T1 (sl) 2020-01-23 2024-03-29 Scipharm S.A.R.L. Kompleks 7-deacetilforskolina in (pvp)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199444B (en) * 1985-09-10 1990-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom
JP3040015B2 (ja) * 1991-08-21 2000-05-08 日研化学株式会社 フォルスコリンの包接化合物
IT1294205B1 (it) 1997-07-23 1999-03-24 Farmigea Spa Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive
US6884885B2 (en) * 2000-12-21 2005-04-26 Cerestar Holding B.V. Production of cyclodextrin complexes
GB0127677D0 (en) * 2001-11-19 2002-01-09 Vianex S A Inclusion complex
KR101195114B1 (ko) 2003-05-20 2012-10-25 (주)하야시바라 생물화학연구소 수 가용성 이소플라본 조성물 및 그 제조 방법 및 그 용도
US6960300B2 (en) 2003-09-08 2005-11-01 Sami Labs Limited Process for preparing water soluble diterpenes and their applications
KR20070038109A (ko) * 2004-08-02 2007-04-09 키에시 파르마슈티시 엣스. 피. 에이. 피록시캠: 베타사이클로덱스트린 포접화합물의 제조방법
BRPI0705319A2 (pt) * 2007-07-23 2009-07-21 Uniao Brasileira De Educacao Manedora Da Pucrs processo para obtenção de um complexo solúvel de resveratrol e/ou seus derivados; complexo de resveratrol e/ou seus derivados; composição nutracêutica
EP2253627A1 (en) 2009-05-21 2010-11-24 ERREGIERRE S.p.A. Inclusion complex of raloxifene hydrochloride and beta-cyclodextrin.
CN103768616B (zh) * 2014-01-08 2015-08-05 中国科学院昆明植物研究所 毛萼乙素环糊精包合物、含有该包合物的药物组合物、其制备方法及应用

Also Published As

Publication number Publication date
CN110325217B (zh) 2023-08-08
SI3565602T1 (sl) 2021-07-30
WO2018127600A1 (en) 2018-07-12
PL3565602T3 (pl) 2021-09-13
KR102583356B1 (ko) 2023-09-26
US20210145791A1 (en) 2021-05-20
EP3565602A1 (en) 2019-11-13
ES2872223T3 (es) 2021-11-02
HUE054617T2 (hu) 2021-09-28
PT3565602T (pt) 2021-05-26
EP3565602B1 (en) 2021-03-03
RS61915B1 (sr) 2021-06-30
LT3565602T (lt) 2021-06-25
US11234957B2 (en) 2022-02-01
JP2020505339A (ja) 2020-02-20
CY1124325T1 (el) 2022-07-22
KR20190107690A (ko) 2019-09-20
CN110325217A (zh) 2019-10-11
SG11201906321WA (en) 2019-08-27
HRP20210863T1 (hr) 2021-08-20
JP7138643B2 (ja) 2022-09-16

Similar Documents

Publication Publication Date Title
DK3315610T3 (da) Fremgangsmåde til fremstilling af fucosylerede oligosaccharider
DK3294700T3 (da) Fremgangsmåde til fremstilling af limonen-4-ol
DK3402773T3 (da) Fremgangsmåde til fremstilling af methanol
DK3473621T3 (da) Fremgangsmåde til fremstilling af diphenylmethan-derivat
DK3126373T3 (da) Fremgangsmåde til fremstilling af amg 416
DK3122444T3 (da) Fremgangsmåde til fremstilling af membraner
DK3397294T3 (da) Fremgangsmåde til fremstilling af 3d-bruskorganoidblok
DK3515990T3 (da) Fremgangsmåde til fremstilling af lignocellulosematerialer
DK3728585T3 (da) Hidtil ukendte fremgangsmåder til fremstilling af oligonukleotider
DK3529233T3 (da) Fremgangsmåde til fremstilling af 3-alkylsulfanyl-2-chlor-n-(1-alkyl-1h-tetrazol-5-yl)-4-trifluoromethyl-benzamider
DK3520591T3 (da) Fremgangsmåde til spredning af gødningsmidler
DK3191498T3 (da) Fremgangsmåde til fremstilling af 2'-o-fucosyllactose
DK3487443T3 (da) Fremgangsmåde til opmåling af en implantat-implantat-situation
DK3534709T3 (da) Substituerede sulfonylamider til bekæmpelse af skadedyr
DK3519394T3 (da) Fremgangsmåde til fremstilling af den krystallinske form af modifikation a af calcobutrol
DK3265443T3 (da) Pyrrolidincarboxamidderivater og fremgangsmåde til fremstilling og anvendelse af samme
DK3423714T3 (da) Fremgangsmåde til generering af elektricitet
DK3252143T3 (da) Metode til produktion af en platelet-lysat-indeholdende gel
DK3507282T3 (da) Fremgangsmåde til fremstilling af indolcarboxamidforbindelser
DK3467005T3 (da) Fremgangsmåde til opnåelse af bionedbrydeligt polyesteretheramid
DK3253743T3 (da) Syntetisk fremgangsmåde til fremstilling af 2-furansyre-derivater
DK3519381T3 (da) Fremgangsmåde til fremstilling af calciumdiglyceroxid
DK3523270T3 (da) Fremgangsmåde til fremstilling af cyclopropyl-substituerede acetophenoner
DK3362405T3 (da) Fremgangsmåde og produktionsenhed til fremstilling af methanol
DK3652187T3 (da) Forbedret fremgangsmåde til fremstilling af imetelstat